{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:22:39Z","timestamp":1783164159591,"version":"3.54.6"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2024ZD0521004"],"award-info":[{"award-number":["2024ZD0521004"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008238","name":"Hebei Provincial Department of Science And Technology","doi-asserted-by":"publisher","award":["246W7701D"],"award-info":[{"award-number":["246W7701D"]}],"id":[{"id":"10.13039\/501100008238","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008238","name":"Hebei Provincial Department of Science And Technology","doi-asserted-by":"publisher","award":["252W7712D"],"award-info":[{"award-number":["252W7712D"]}],"id":[{"id":"10.13039\/501100008238","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008238","name":"Hebei Provincial Department of Science And Technology","doi-asserted-by":"publisher","award":["262W7710D"],"award-info":[{"award-number":["262W7710D"]}],"id":[{"id":"10.13039\/501100008238","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003787","name":"Hebei Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["H2023423001"],"award-info":[{"award-number":["H2023423001"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003787","name":"Hebei Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["H2025423021"],"award-info":[{"award-number":["H2025423021"]}],"id":[{"id":"10.13039\/501100003787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013077","name":"National Science and Technology Planning Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013077","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005891","name":"National Administration of Traditional Chinese Medicine","doi-asserted-by":"publisher","award":["GZY-KJS-2023-025"],"award-info":[{"award-number":["GZY-KJS-2023-025"]}],"id":[{"id":"10.13039\/501100005891","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.jep.2026.121948","type":"journal-article","created":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T15:24:17Z","timestamp":1780327457000},"page":"121948","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Shengyang Xiehuo formula regulates lipid droplet-mitochondrial interaction via TNF-\u03b1\/PPAR\u03b3 axis to treat chronic atrophic gastritis"],"prefix":"10.1016","volume":"369","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9365-3298","authenticated-orcid":false,"given":"Yuxi","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Zhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengli","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanru","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanru","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoyi","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib1","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3390\/microorganisms12010222","article-title":"Helicobacter pylori: a contemporary perspective on pathogenesis, diagnosis and treatment strategies","volume":"12","author":"Ali","year":"2024","journal-title":"Microorganisms"},{"issue":"2","key":"10.1016\/j.jep.2026.121948_bib2","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02355-21","article-title":"Synergistic effects of licorice root and walnut leaf extracts on gastrointestinal candidiasis, inflammation and gut microbiota composition in mice","volume":"10","author":"Authier","year":"2022","journal-title":"Microbiol. Spectr."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib3","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1186\/s13048-025-01826-9","article-title":"Betaine alleviates letrozole-induced polycystic ovarian syndrome in rats by regulating oxidative stress and inflammation and restoring the proliferation- apoptosis balance","volume":"18","author":"Babaeenezhad","year":"2025","journal-title":"J. Ovarian Res."},{"issue":"3","key":"10.1016\/j.jep.2026.121948_bib4","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J. Clin."},{"issue":"48","key":"10.1016\/j.jep.2026.121948_bib7","article-title":"Clog P-guided development of multi-colored buffering fluorescent probes for super-resolution imaging of lipid droplet dynamics","volume":"11","author":"Chen","year":"2024","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.jep.2026.121948_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156346","article-title":"Xiaohuafuning tang intervenes liver-depression-and-spleen-deficiency syndrome chronic-atrophic-gastritis by reshaping amino acid metabolism through gut microbiota","volume":"136","author":"Chen","year":"2025","journal-title":"Phytomedicine: international journal of phytotherapy and phytopharmacology"},{"issue":"2","key":"10.1016\/j.jep.2026.121948_bib5","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/MCG.0000000000001663","article-title":"A randomized double-blind clinical trial of weierkang pills for the treatment of chronic atrophic gastritis","volume":"57","author":"Chen","year":"2023","journal-title":"J. Clin. Gastroenterol."},{"issue":"12","key":"10.1016\/j.jep.2026.121948_bib6","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.3390\/antiox12122117","article-title":"The impact of follicular fluid oxidative stress levels on the outcomes of assisted reproductive therapy","volume":"12","author":"Chen","year":"2023","journal-title":"Antioxidants"},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1186\/s12944-025-02782-5","article-title":"Integrative analysis of serum lipids and chronic gastritis: causal insights from Mendelian randomization and experimental models","volume":"24","author":"Chu","year":"2025","journal-title":"Lipids Health Dis."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib10","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/s43556-025-00366-4","article-title":"Long-chain acyl-CoA synthetases: biological functions, diseases and therapeutic targets","volume":"6","author":"Deng","year":"2025","journal-title":"Molecular biomedicine"},{"key":"10.1016\/j.jep.2026.121948_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2024.1342913","article-title":"Strategies of Helicobacter pylori in evading host innate and adaptive immunity: insights and prospects for therapeutic targeting","volume":"14","author":"Fan","year":"2024","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"2","key":"10.1016\/j.jep.2026.121948_bib11","doi-asserted-by":"crossref","first-page":"168","DOI":"10.21147\/j.issn.1000-9604.2021.02.05","article-title":"Screening for gastric cancer in China: advances, challenges and visions","volume":"33","author":"Fan","year":"2021","journal-title":"Chin. J. Cancer Res."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib13","article-title":"Coprevalence of modifiable gastric cancer risk factors and gastric health among Chinese high-risk groups","volume":"15","author":"Feng","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.121948_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.bpg.2025.101979","article-title":"Early diagnosis of gastric cancer: endoscopy and artificial intelligence","volume":"75","author":"Gon\u00e7alves","year":"2025","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib15","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/s13020-024-01045-2","article-title":"Integrated analysis of metabolome, lipidome, and gut microbiome reveals the immunomodulation of astragali radix in healthy human subjects","volume":"19","author":"Gui","year":"2024","journal-title":"Chin. Med."},{"issue":"10","key":"10.1016\/j.jep.2026.121948_bib16","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1038\/s42255-022-00644-3","article-title":"Cdo1 promotes PPAR\u03b3-mediated adipose tissue lipolysis in male mice","volume":"4","author":"Guo","year":"2022","journal-title":"Nat. Metab."},{"key":"10.1016\/j.jep.2026.121948_bib17","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.1009705","article-title":"Pharmacological and molecular analysis of the effects of huangqi jianzhong decoction on proliferation and apoptosis in GES-1 cells infected with H. pylori","volume":"13","author":"Hu","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"6","key":"10.1016\/j.jep.2026.121948_bib19","first-page":"1","article-title":"Atractylodin inhibits ferroptosis in sepsis-induced acute gastrointestinal injury via SIRT3\/PRDX3","volume":"32","author":"Hu","year":"2025","journal-title":"Mol. Med. Rep."},{"issue":"3","key":"10.1016\/j.jep.2026.121948_bib20","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3390\/ph18030413","article-title":"From traditional efficacy to drug design: a review of astragali radix","volume":"18","author":"Jin","year":"2025","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.jep.2026.121948_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157197","article-title":"Baicalin ameliorates high-fat diet induced MAFLD by inhibiting ERK\/PPAR\u03b3\/CD36 pathway","volume":"147","author":"Lei","year":"2025","journal-title":"Phytomedicine : international journal of phytotherapy and phytopharmacology"},{"issue":"8","key":"10.1016\/j.jep.2026.121948_bib25","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.3390\/foods12081652","article-title":"Effects of different drying methods on drying characteristics and quality of Glycyrrhiza uralensis (licorice)","volume":"12","author":"Li","year":"2023","journal-title":"Foods"},{"issue":"20","key":"10.1016\/j.jep.2026.121948_bib27","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202304326","article-title":"A natural peptide from A traditional Chinese medicine has the potential to treat chronic atrophic gastritis by activating gastric stem cells","volume":"11","author":"Li","year":"2024","journal-title":"Adv. Sci."},{"issue":"10","key":"10.1016\/j.jep.2026.121948_bib26","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1080\/15548627.2023.2213984","article-title":"Impaired lipophagy induced-microglial lipid droplets accumulation contributes to the buildup of TREM1 in diabetes-associated cognitive impairment","volume":"19","author":"Li","year":"2023","journal-title":"Autophagy"},{"key":"10.1016\/j.jep.2026.121948_bib23","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.phymed.2018.09.174","article-title":"A comprehensive review and perspectives on pharmacology and toxicology of saikosaponins","volume":"50","author":"Li","year":"2018","journal-title":"Phytomedicine: international journal of phytotherapy and phytopharmacology"},{"key":"10.1016\/j.jep.2026.121948_bib24","article-title":"Manpixiao decoction halted the malignant transformation of precancerous lesions of gastric cancer: from network prediction to In-Vivo verification","volume":"13","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.121948_bib22","article-title":"Precancerous pathways to gastric cancer: a review of experimental animal models recapitulating the correa Cascade","volume":"13","author":"Li","year":"2025","journal-title":"Front. Cell Dev. Biol."},{"issue":"5","key":"10.1016\/j.jep.2026.121948_bib28","doi-asserted-by":"crossref","first-page":"598","DOI":"10.2174\/1573409919666230720141115","article-title":"Amalgamated pharmacoinformatics study to investigate the mechanism of xiao jianzhong tang against chronic atrophic gastritis","volume":"20","author":"Lian","year":"2024","journal-title":"Curr. Comput. Aided Drug Des."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib33","article-title":"Exploring the mechanism of Notopterygii rhizoma et radix in the treatment of psoriasis using a network Pharmacology approach and experimental validation","volume":"15","author":"Liu","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.121948_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.119272","article-title":"Vitexin alleviates MNNG-induced chronic atrophic gastritis via inhibiting NLRP3 inflammasome","volume":"340","author":"Liu","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121948_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2022.106440","article-title":"Berberine for gastric cancer prevention and treatment: multi-step actions on the Correa's Cascade underlie its therapeutic effects","volume":"184","author":"Liu","year":"2022","journal-title":"Pharmacol. Res."},{"issue":"2","key":"10.1016\/j.jep.2026.121948_bib32","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.chmed.2023.10.006","article-title":"Protective role of fruits of Rosa odorata var. gigantea against WIRS-induced gastric mucosal injury in rats by modulating pathway related to inflammation, oxidative stress and apoptosis","volume":"16","author":"Liu","year":"2024","journal-title":"Chinese herbal medicines"},{"key":"10.1016\/j.jep.2026.121948_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154557","article-title":"Bile acid metabolism involved into the therapeutic action of xiaojianzhong tang via gut microbiota to treat chronic atrophic gastritis in rats","volume":"109","author":"Liu","year":"2023","journal-title":"Phytomedicine: international journal of phytotherapy and phytopharmacology"},{"key":"10.1016\/j.jep.2026.121948_bib31","first-page":"155","article-title":"Alloprevotella can be considered as a potential oral biomarker in intestinal metaphase of gastric patients","volume":"308","author":"Liu","year":"2023","journal-title":"Stud. Health Technol. Inf."},{"issue":"Pt A","key":"10.1016\/j.jep.2026.121948_bib35","article-title":"Pharmacodynamics and pharmacological mechanism of moluodan concentrated pill in the treatment of atrophic gastritis: a network pharmacological study and in vivo experiments","volume":"318","author":"Lou","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121948_bib36","article-title":"Regulating PPARG reduces lipid accumulation in microglia and promotes functional recovery after spinal cord injury","author":"Luo","year":"2025","journal-title":"Adv. Sci."},{"issue":"6","key":"10.1016\/j.jep.2026.121948_bib37","first-page":"306","article-title":"The efficacy of morodan in combination with rabeprazole for the treatment of chronic gastritis and its impact on gastric mucosal repair","volume":"29","author":"Ma","year":"2023","journal-title":"Alternative Ther. Health Med."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib38","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1186\/s12967-025-06458-7","article-title":"Changes of gastric microflora and metabolites in patients with chronic atrophic gastritis","volume":"23","author":"Ma","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.jep.2026.121948_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2023.1057216","article-title":"Cancer metabolic features allow discrimination of tumor from white blood cells by label-free multimodal optical imaging","volume":"11","author":"Mangini","year":"2023","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.jep.2026.121948_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2025.157061","article-title":"Inflammation in gastric epithelium associated with infection of Helicobacter pylori is induced by inhibited PPAR\u03b3 pathway: the key role of TLRs\/NF-\u03baB axis","volume":"196","author":"Mao","year":"2025","journal-title":"Cytokine"},{"issue":"13","key":"10.1016\/j.jep.2026.121948_bib41","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.3390\/foods12132446","article-title":"The effect of milking frequency, breed, and stage of lactation on the milk fat globule zize and fatty acid vomposition in sheep's milk","volume":"12","author":"Massouras","year":"2023","journal-title":"Foods"},{"issue":"6","key":"10.1016\/j.jep.2026.121948_bib42","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1038\/s42255-024-01047-2","article-title":"Glycolytic enzyme PFKL governs lipolysis by promoting lipid droplet-mitochondria tethering to enhance \u03b2-oxidation and tumor cell proliferation","volume":"6","author":"Meng","year":"2024","journal-title":"Nat. Metab."},{"issue":"14","key":"10.1016\/j.jep.2026.121948_bib43","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1016\/j.devcel.2023.05.006","article-title":"PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to- mitochondria fatty acid transport","volume":"58","author":"Miner","year":"2023","journal-title":"Dev. Cell"},{"issue":"11","key":"10.1016\/j.jep.2026.121948_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcmgh.2025.101593","article-title":"Hepatic ketogenesis regulates lipid homeostasis via ACSL1-mediated fatty acid partitioning","volume":"19","author":"Mooli","year":"2025","journal-title":"Cellular and molecular gastroenterology and hepatology"},{"key":"10.1016\/j.jep.2026.121948_bib45","doi-asserted-by":"crossref","first-page":"30","DOI":"10.33393\/dti.2024.2707","article-title":"Molecular targets and therapeutic potential of baicalein: a review","volume":"18","author":"Munjal","year":"2024","journal-title":"Drug Target Insights"},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib46","doi-asserted-by":"crossref","DOI":"10.3748\/wjg.v32.i1.113181","article-title":"Anwei decoction alleviates chronic atrophic gastritis by modulating the gut microbiota-metabolite axis and inflammasome activity","volume":"32","author":"Qin","year":"2026","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.jep.2026.121948_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.679897","article-title":"Kaempferol alleviates murine experimental colitis by restoring gut microbiota and inhibiting the LPS-TLR4-NF-\u03baB axis","volume":"12","author":"Qu","year":"2021","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.jep.2026.121948_bib48","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1053\/j.gastro.2018.05.026","article-title":"Cost effectiveness of gastric cancer screening according to race and ethnicity","volume":"155","author":"Saumoy","year":"2018","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib51","article-title":"Mannose-B from Codonopsis pilosula modulates LAMB1 expression to enhance trophoblast function and alleviate subchorionic hematoma","volume":"15","author":"Sun","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.121948_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.114294","article-title":"Glycyrrhizin alleviates brain injury in necrotizing enterocolitis model mice by suppressing HMGB1\/TLR4 pathway","volume":"150","author":"Sun","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2026.121948_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1257817","article-title":"Helicobacter pylori infection: a dynamic process from diagnosis to treatment","volume":"13","author":"Sun","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"22","key":"10.1016\/j.jep.2026.121948_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e40427","article-title":"Pharmacology, medical uses, and clinical translational challenges of saikosaponin A: A review","volume":"10","author":"Sun","year":"2024","journal-title":"Heliyon"},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib53","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s11655-015-2114-5","article-title":"Randomized double-blind clinical trial of moluodan for the treatment of chronic atrophic gastritis with dysplasia","volume":"22","author":"Tang","year":"2016","journal-title":"Chin. J. Integr. Med."},{"issue":"9","key":"10.1016\/j.jep.2026.121948_bib59","doi-asserted-by":"crossref","DOI":"10.3748\/wjg.v31.i9.102053","article-title":"Traditional Chinese medicine for chronic atrophic gastritis: efficacy, mechanisms and targets","volume":"31","author":"Wang","year":"2025","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib56","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s13020-024-00963-5","article-title":"Development of an artificial intelligent model for pre-endoscopic screening of precancerous lesions in gastric cancer","volume":"19","author":"Wang","year":"2024","journal-title":"Chin. Med."},{"issue":"17","key":"10.1016\/j.jep.2026.121948_bib54","doi-asserted-by":"crossref","first-page":"932","DOI":"10.21037\/atm-22-3749","article-title":"Jian-pi-yi-qi-fang ameliorates chronic atrophic gastritis in rats through promoting the proliferation and differentiation of gastric stem cells","volume":"10","author":"Wang","year":"2022","journal-title":"Ann. Transl. Med."},{"issue":"4","key":"10.1016\/j.jep.2026.121948_bib57","first-page":"853","article-title":"Research progress in pharmacological effects of gypsum fibrosum and material basis for its heat-clearing effect","volume":"49","author":"Wang","year":"2024","journal-title":"Zhongguo Zhongyao Zazhi"},{"issue":"5","key":"10.1016\/j.jep.2026.121948_bib58","article-title":"Helicobacter pylori triggers inflammation and oncogenic transformation by perturbing the immune microenvironment. Biochimica et biophysica acta","volume":"1879","author":"Wang","year":"2024","journal-title":"Reviews on cancer"},{"key":"10.1016\/j.jep.2026.121948_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154558","article-title":"Antidepressant effects of the traditional Chinese herbal formula xiao-yao-san and its bioactive ingredients","volume":"109","author":"Wang","year":"2023","journal-title":"Phytomedicine: international journal of phytotherapy and phytopharmacology"},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib60","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s13098-025-01680-1","article-title":"Plin5: a potential therapeutic target for type 2 diabetes mellitus","volume":"17","author":"Wei","year":"2025","journal-title":"Diabetol. Metab. Syndr."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib63","article-title":"Metabolomic biomarkers discovery across chronic gastritis to gastric cancer progression","volume":"15","author":"Yang","year":"2025","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib62","doi-asserted-by":"crossref","first-page":"7746","DOI":"10.1038\/s41467-024-52218-4","article-title":"Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in Male mice","volume":"15","author":"Yang","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jep.2026.121948_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118903","article-title":"Berberine regulates macrophage polarization through IL-4-STAT6 signaling pathway in helicobacter pylori-induced chronic atrophic gastritis","volume":"266","author":"Yang","year":"2021","journal-title":"Life Sci."},{"key":"10.1016\/j.jep.2026.121948_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120274","article-title":"Research progress on extraction, purification, biotransformation, pharmacological effects, toxicity, combined therapy and new dosage forms of saikosaponins","volume":"352","author":"Yang","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"8","key":"10.1016\/j.jep.2026.121948_bib65","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.3390\/molecules29081691","article-title":"The antioxidant action of astragali radix: its active components and molecular basis","volume":"29","author":"Yao","year":"2024","journal-title":"Molecules"},{"issue":"43","key":"10.1016\/j.jep.2026.121948_bib66","doi-asserted-by":"crossref","first-page":"16724","DOI":"10.1074\/jbc.RA118.004049","article-title":"Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways","volume":"293","author":"Young","year":"2018","journal-title":"J. Biol. Chem."},{"issue":"52","key":"10.1016\/j.jep.2026.121948_bib67","article-title":"Clinical efficacy of moluodan in the treatment of chronic atrophic gastritis: a protocol for systematic review and meta-analysis","volume":"101","author":"Yu","year":"2022","journal-title":"Medicine (Baltim.)"},{"issue":"3","key":"10.1016\/j.jep.2026.121948_bib69","doi-asserted-by":"crossref","DOI":"10.3748\/wjg.v31.i3.96582","article-title":"Traditional Chinese medicine in the treatment of helicobacter pylori-related gastritis: the mechanisms of signalling pathway regulations","volume":"31","author":"Zhang","year":"2025","journal-title":"World J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib68","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s13020-024-00937-7","article-title":"Traditional uses, phytochemistry, pharmacology, quality control and clinical studies of cimicifugae rhizoma: a comprehensive review","volume":"19","author":"Zhang","year":"2024","journal-title":"Chin. Med."},{"key":"10.1016\/j.jep.2026.121948_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2026.121183","article-title":"Myricanol modulates PPAR\u03b3\/ACSL1\/SCD1 metabolic signaling pathway to promote mitochondria biogenesis and fatty acid \u03b2-oxidation in high-fat diet-induced Obese mice","volume":"360","author":"Zhang","year":"2026","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.121948_bib71","doi-asserted-by":"crossref","first-page":"813","DOI":"10.2147\/JIR.S496703","article-title":"The clinical value of the combined detection of systemic immune- inflammation index (SII), systemic inflammation response index (SIRI), and prognostic nutritional index (PNI) in early diagnosis of gastric cancer","volume":"18","author":"Zheng","year":"2025","journal-title":"J. Inflamm. Res."},{"issue":"1","key":"10.1016\/j.jep.2026.121948_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2024.115203","article-title":"Ergosterol alleviates hepatic steatosis and insulin resistance via promoting fatty acid \u03b2-oxidation by activating mitochondrial ACSL1","volume":"44","author":"Zheng","year":"2025","journal-title":"Cell Rep."},{"issue":"4","key":"10.1016\/j.jep.2026.121948_bib74","first-page":"12","article-title":"Efficacy observation of modified bupiwei xieyinhuo shengyang decoction and weifuchun tablets on chronic atrophic gastritis complicated with anxiety and depression","volume":"39","author":"Zhou","year":"2023","journal-title":"Shanxi J. Traditional Chinese Med."},{"key":"10.1016\/j.jep.2026.121948_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153837","article-title":"Network pharmacology to unveil the mechanism of moluodan in the treatment of chronic atrophic gastritis","volume":"95","author":"Zhou","year":"2022","journal-title":"Phytomedicine"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126008020?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126008020?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T11:03:49Z","timestamp":1783163029000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126008020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":73,"alternative-id":["S0378874126008020"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.121948","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Shengyang Xiehuo formula regulates lipid droplet-mitochondrial interaction via TNF-\u03b1\/PPAR\u03b3 axis to treat chronic atrophic gastritis","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.121948","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"121948"}}