{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:45:28Z","timestamp":1785883528454,"version":"3.56.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100011710","name":"Shaanxi Province Department of Science and Technology","doi-asserted-by":"publisher","award":["2025SF-YBXM-094"],"award-info":[{"award-number":["2025SF-YBXM-094"]}],"id":[{"id":"10.13039\/501100011710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008387","name":"Xi&apos;an Municipal Bureau of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008387","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020754","name":"Xi&apos;an Municipal Peoples Government","doi-asserted-by":"publisher","award":["25YXYJZD00006"],"award-info":[{"award-number":["25YXYJZD00006"]}],"id":[{"id":"10.13039\/501100020754","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jep.2026.122055","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T15:48:23Z","timestamp":1781624903000},"page":"122055","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Buyiniuxi pill promotes hair regrowth in a DHT-induced mouse model of androgenetic alopecia"],"prefix":"10.1016","volume":"370","author":[{"given":"Wei","family":"Pang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu Huan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Xia","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8997-7490","authenticated-orcid":false,"given":"Xiao Qiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jep.2026.122055_bib1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.jaad.2017.02.054","article-title":"The effectiveness of treatments for androgenetic alopecia: a systematic review and meta-analysis","volume":"77","author":"Adil","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"issue":"1","key":"10.1016\/j.jep.2026.122055_bib2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/s13287-023-03398-1","article-title":"Cell-free fat extract restores hair loss: a novel therapeutic strategy for androgenetic alopecia","volume":"14","author":"Cai","year":"2023","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jep.2026.122055_bib3","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.mce.2017.09.009","article-title":"Androgens and androgen receptor action in skin and hair follicles","volume":"465","author":"Ceruti","year":"2018","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.jep.2026.122055_bib4","doi-asserted-by":"crossref","first-page":"7349","DOI":"10.2147\/DDDT.S542000","article-title":"Androgenetic alopecia: an update on pathogenesis and pharmacological treatment","volume":"19","author":"Chen","year":"2025","journal-title":"Drug Des. Dev. Ther."},{"issue":"8","key":"10.1016\/j.jep.2026.122055_bib5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1007\/s40265-023-01880-x","article-title":"Androgenetic alopecia: therapy update","volume":"83","author":"Devjani","year":"2023","journal-title":"Drugs"},{"issue":"4","key":"10.1016\/j.jep.2026.122055_bib6","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/jocd.12930","article-title":"An overview of herbal alternatives in androgenetic alopecia","volume":"18","author":"Dhariwala","year":"2019","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.jep.2026.122055_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115320","article-title":"Exploring the effects of Chinese herbal ingredients on the signaling pathway of alopecia and the screening of effective Chinese herbal compounds","volume":"294","author":"Dou","year":"2022","journal-title":"J. Ethnopharmacol."},{"issue":"22","key":"10.1016\/j.jep.2026.122055_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1462399402005112","article-title":"Androgenetic alopecia: pathogenesis and potential for therapy","volume":"4","author":"Ellis","year":"2002","journal-title":"Expert Rev. Mol. Med."},{"key":"10.1016\/j.jep.2026.122055_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111247","article-title":"Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia","volume":"137","author":"Fu","year":"2021","journal-title":"Biomed. Pharmacother."},{"issue":"16","key":"10.1016\/j.jep.2026.122055_bib10","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.2174\/1381612829666230505100147","article-title":"Natural compounds used for treating hair loss","volume":"29","author":"Gasmi","year":"2023","journal-title":"Curr. Pharm. Des."},{"issue":"4","key":"10.1016\/j.jep.2026.122055_bib11","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1080\/09546634.2021.1959506","article-title":"Finasteride for hair loss: a review","volume":"33","author":"Gupta","year":"2022","journal-title":"J. Dermatol. Treat."},{"issue":"5","key":"10.1016\/j.jep.2026.122055_bib13","article-title":"Medications most commonly associated with erectile dysfunction: evaluation of the food and drug administration national pharmacovigilance database","volume":"10","author":"Kaplan-Marans","year":"2022","journal-title":"Sex. Med."},{"issue":"14","key":"10.1016\/j.jep.2026.122055_bib12","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1007\/s40265-016-0629-5","article-title":"Androgenetic alopecia: an update of treatment options","volume":"76","author":"Kelly","year":"2016","journal-title":"Drugs"},{"key":"10.1016\/j.jep.2026.122055_bib15","series-title":"Bencao Gangmu (Compendium of Materia Medica)","author":"Li","year":"2014"},{"key":"10.1016\/j.jep.2026.122055_bib16","series-title":"Yifang Leiju","year":"2022"},{"issue":"1","key":"10.1016\/j.jep.2026.122055_bib14","first-page":"223","article-title":"Antinociceptive and anti-inflammatory activities of Cuscuta chinensis seeds in mice","volume":"42","author":"Liao","year":"2014","journal-title":"Phytomedicine"},{"issue":"2","key":"10.1016\/j.jep.2026.122055_bib17","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/0976-0105.177703","article-title":"A simple practice guide for dose conversion between animals and human","volume":"7","author":"Nair","year":"2016","journal-title":"J. Basic Clin. Pharm."},{"issue":"1","key":"10.1016\/j.jep.2026.122055_bib18","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1186\/s13287-024-03906-x","article-title":"Improvement of androgenic alopecia by extracellular vesicles secreted from hyaluronic acid-stimulated induced mesenchymal stem cells","volume":"15","author":"Oh","year":"2024","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jep.2026.122055_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.119347","article-title":"Dahuang-gancao decoction ameliorates testosterone-induced androgenetic alopecia in mice","volume":"341","author":"Qian","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2026.122055_bib20","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.3390\/cells12121671","article-title":"The PI3K-Akt-mTOR and associated signaling pathways as molecular drivers of immune-mediated inflammatory skin diseases: update on therapeutic strategy using natural and synthetic compounds","volume":"12","author":"Roy","year":"2023","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.jep.2026.122055_bib21","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1111\/j.1365-2133.2003.05565.x","article-title":"Androgenetic alopecia in men aged 40-69 years: prevalence and risk factors","volume":"149","author":"Severi","year":"2003","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jep.2026.122055_bib22","series-title":"Bencao Jing Jizhu","author":"Tao","year":"2023"},{"key":"10.1016\/j.jep.2026.122055_bib25","volume":"vol. 1","year":"2016"},{"key":"10.1016\/j.jep.2026.122055_bib23","article-title":"Pilose antler extracts promotes hair growth in androgenetic alopecia mice by activating hair follicle stem cells via the AKT and Wnt pathways","volume":"15","author":"Wang","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.122055_bib24","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.freeradbiomed.2025.05.427","article-title":"Ergothioneine regulates the paracrine of dermal papilla cells through SIRT1\/Nrf2 pathway to antagonize oxidative stress and natural hair follicle aging","volume":"237","author":"Wang","year":"2025","journal-title":"Free Radic. Biol. Med."},{"issue":"5","key":"10.1016\/j.jep.2026.122055_bib26","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1080\/14656566.2020.1721463","article-title":"A review of the treatment of male pattern hair loss","volume":"21","author":"York","year":"2020","journal-title":"Expert Opin. Pharmacother."},{"key":"10.1016\/j.jep.2026.122055_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2022.120441","article-title":"Structural characterization and anti-inflammatory effects of an arabinan isolated from Rehmannia glutinosa Libosch","volume":"303","author":"Zhang","year":"2023","journal-title":"Carbohydr. Polym."},{"issue":"1","key":"10.1016\/j.jep.2026.122055_bib28","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1186\/s13287-025-04806-4","article-title":"The human umbilical cord-mesenchymal stem cell secretome regulates hair growth and cycle transition by promoting methylthioadenosine synthesis via the PI3K\/AKT\/mTOR pathway","volume":"16","author":"Zhang","year":"2025","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jep.2026.122055_bib29","series-title":"Shengji Zonglu","year":"2018"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126009098?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126009098?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:54:32Z","timestamp":1785880472000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126009098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":29,"alternative-id":["S0378874126009098"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.122055","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Buyiniuxi pill promotes hair regrowth in a DHT-induced mouse model of androgenetic alopecia","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.122055","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"122055"}}