{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:44:05Z","timestamp":1785887045837,"version":"3.56.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010890","name":"Central People's Government of the People's Republic of China Scholarship Programme","doi-asserted-by":"publisher","award":["2025ZY01023"],"award-info":[{"award-number":["2025ZY01023"]}],"id":[{"id":"10.13039\/501100010890","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005199","name":"Chinese Medicine Research Program of Zhejiang Province","doi-asserted-by":"publisher","award":["2025E10064"],"award-info":[{"award-number":["2025E10064"]}],"id":[{"id":"10.13039\/501100005199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015308","name":"Xinjiang Uygur Autonomous Region Department of Science and Technology","doi-asserted-by":"publisher","award":["2025B04029"],"award-info":[{"award-number":["2025B04029"]}],"id":[{"id":"10.13039\/501100015308","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004863","name":"Zhejiang Chinese Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004863","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.jep.2026.122064","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T23:17:24Z","timestamp":1781651844000},"page":"122064","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Targeted discovery of anti-skin aging peptides from Camelus bactrianus placenta: Multi-activity screening, network pharmacology, and in vitro validation focusing on MMP-1 inhibition"],"prefix":"10.1016","volume":"370","author":[{"given":"Linkun","family":"Tian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingshan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hairong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengdong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheyuan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongguang","family":"Tai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeyu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luping","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1680-4869","authenticated-orcid":false,"given":"Quanlong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.jep.2026.122064_bib1","doi-asserted-by":"crossref","first-page":"3107","DOI":"10.1039\/D2FO03834J","article-title":"Characterization and anti-aging effects of Opuntia ficus-indica (L.) Miller extracts in a D-galactose-induced skin aging model","volume":"14","author":"Abbas","year":"2023","journal-title":"Food Funct."},{"issue":"14","key":"10.1016\/j.jep.2026.122064_bib2","doi-asserted-by":"crossref","first-page":"7890","DOI":"10.1002\/jsfa.70042","article-title":"Production, purification and identification of novel antioxidant peptides from Piaractus brachypomus (red-bellied pacu) using Pediococcus pentosaceus fermentation","volume":"105","author":"Babu","year":"2025","journal-title":"J. Sci. Food Agric."},{"key":"10.1016\/j.jep.2026.122064_bib3","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.ijbiomac.2020.06.072","article-title":"Marine microbial alkaline protease: an efficient and essential tool for various industrial applications","volume":"161","author":"Barzkar","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"issue":"1","key":"10.1016\/j.jep.2026.122064_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000599","article-title":"A proteomic atlas of senescence-associated secretomes for aging biomarker development","volume":"18","author":"Basisty","year":"2020","journal-title":"PLoS Biol."},{"key":"10.1016\/j.jep.2026.122064_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156010","article-title":"Panax ginseng extract prevents UVB-induced skin photodamage by modulating VMP1-mediated ER stress","volume":"134","author":"Chen","year":"2024","journal-title":"Phytomedicine : international journal of phytotherapy and phytopharmacology"},{"issue":"12","key":"10.1016\/j.jep.2026.122064_bib6","first-page":"234","article-title":"Preparation and stability study of antioxidant peptides from Camel Placenta","volume":"50","author":"Chen","year":"2024","journal-title":"Food Ferment. Ind."},{"key":"10.1016\/j.jep.2026.122064_bib7","article-title":"Advances in the pharmacology and mechanism of anti-skin aging in tonifying traditional Chinese medicines","author":"Chen","year":"2026","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2026.122064_bib8","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s12896-025-01050-9","article-title":"Recombinant type I & III chimeric collagen significantly enhances the vitality of fibroblasts and decelerates the skin aging process","volume":"25","author":"Chen","year":"2025","journal-title":"BMC Biotechnol."},{"issue":"2","key":"10.1016\/j.jep.2026.122064_bib9","first-page":"56","article-title":"Advances in camel placenta powder and its current clinical applications in Mongolian medicine","volume":"25","author":"Chen","year":"2019","journal-title":"Journal of Medicine and Pharmacy of Chinese Minorities"},{"issue":"11","key":"10.1016\/j.jep.2026.122064_bib10","first-page":"102","article-title":"Research progress and prospects of using Mongolian medicine halayazhu (dry powder of Camel Placenta) for treating diabetes","volume":"31","author":"Chen","year":"2025","journal-title":"Journal of Medicine & Pharmacy of Chinese Minorities"},{"key":"10.1016\/j.jep.2026.122064_bib11","first-page":"666","article-title":"Silk fibroin counteracts fibroblast senescence to restore ECM homeostasis in aged skin","volume":"58","author":"Cheng","year":"2026","journal-title":"Bioact. Mater."},{"issue":"26","key":"10.1016\/j.jep.2026.122064_bib12","doi-asserted-by":"crossref","first-page":"21222","DOI":"10.1007\/s11356-017-9671-4","article-title":"Effect of processing conditions on degree of hydrolysis, ACE inhibition, and antioxidant activities of protein hydrolysate from Acetes indicus","volume":"24","author":"Dhanabalan","year":"2017","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"23","key":"10.1016\/j.jep.2026.122064_bib13","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.70281","article-title":"Integrative network pharmacology and proteomics decipher the immunomodulatory mechanism of sulforaphane against intrinsic skin aging","volume":"69","author":"Du","year":"2025","journal-title":"Mol. Nutr. Food Res."},{"issue":"2","key":"10.1016\/j.jep.2026.122064_bib14","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.chembiol.2021.12.001","article-title":"Making the cut with protease engineering","volume":"29","author":"Dyer","year":"2022","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.jep.2026.122064_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.meatsci.2025.110006","article-title":"Determination of heterocyclic aromatic amine content of protein extracts and protein hydrolysates obtained from meat trimming wastes under different process conditions","volume":"233","author":"Ekiz Terzio\u011flu","year":"2026","journal-title":"Meat Sci."},{"key":"10.1016\/j.jep.2026.122064_bib16","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.ijbiomac.2019.01.081","article-title":"A systematic reconsideration on proteases","volume":"128","author":"Gurumallesh","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jep.2026.122064_bib17","article-title":"Effect of sheep placenta extract on D-galactose-induced aging mouse","volume":"16","author":"He","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.122064_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.133110","article-title":"Novel insight into the transformation of peptides and potential benefits in brown fermented goat milk by mesoporous magnetic dispersive solid phase extraction-based peptidomics","volume":"389","author":"Jia","year":"2022","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2026.122064_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157360","article-title":"Bazi Bushen capsule alleviates skin photoaging by targeting the KEAP1-NRF2 pathway","volume":"148","author":"Jiang","year":"2025","journal-title":"Phytomedicine : international journal of phytotherapy and phytopharmacology"},{"key":"10.1016\/j.jep.2026.122064_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157692","article-title":"Anwulignan mitigates UVB-induced skin photodamage by dual activation of the Nrf2\/PINK1\/Parkin and Nrf2\/SLC7A11\/GPX4 signaling pathways","volume":"150","author":"Jiang","year":"2026","journal-title":"Phytomedicine : international journal of phytotherapy and phytopharmacology"},{"issue":"2","key":"10.1016\/j.jep.2026.122064_bib21","doi-asserted-by":"crossref","first-page":"172","DOI":"10.5851\/kosfa.2020.e2","article-title":"Hydrolysis conditions of porcine blood proteins and antimicrobial effects of their hydrolysates","volume":"40","author":"Jin","year":"2020","journal-title":"Food science of animal resources"},{"issue":"10","key":"10.1016\/j.jep.2026.122064_bib22","doi-asserted-by":"crossref","first-page":"8711","DOI":"10.3168\/jds.2018-14586","article-title":"Inhibitory properties of camel whey protein hydrolysates toward liver cancer cells, dipeptidyl peptidase-IV, and inflammation","volume":"101","author":"Kamal","year":"2018","journal-title":"J. Dairy Sci."},{"issue":"21","key":"10.1016\/j.jep.2026.122064_bib23","doi-asserted-by":"crossref","first-page":"5316","DOI":"10.1021\/acs.jpcb.7b09771","article-title":"Conformational dynamics of matrix Metalloproteinase-1\u00b7Triple-Helical peptide complexes","volume":"122","author":"Karabencheva-Christova","year":"2018","journal-title":"J. Phys. Chem. B"},{"issue":"10","key":"10.1016\/j.jep.2026.122064_bib24","doi-asserted-by":"crossref","first-page":"4956","DOI":"10.1111\/jocd.14908","article-title":"A network pharmacology-based study of the potential targets and mechanisms of action of Qibao Meiran Dan in delaying skin aging","volume":"21","author":"Ke","year":"2022","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.jep.2026.122064_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118421","article-title":"Study on the anti-skin aging effect and mechanism of Sijunzi Tang based on network pharmacology and experimental validation","volume":"333","author":"Ke","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"12","key":"10.1016\/j.jep.2026.122064_bib26","doi-asserted-by":"crossref","DOI":"10.3390\/antiox14121424","article-title":"\u03b2-Nicotinamide mononucleotide enhances skin barrier function and attenuates UV-B-Induced photoaging in mice","volume":"14","author":"Kim","year":"2025","journal-title":"Antioxidants"},{"issue":"1","key":"10.1016\/j.jep.2026.122064_bib27","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s00403-025-04518-y","article-title":"From destruction to protection: rethinking MMP-1 in skin aging and anti-aging strategies","volume":"318","author":"Lai","year":"2026","journal-title":"Arch. Dermatol. Res."},{"issue":"41","key":"10.1016\/j.jep.2026.122064_bib28","doi-asserted-by":"crossref","first-page":"26190","DOI":"10.1021\/acs.jafc.5c09950","article-title":"Novel antiphotoaging peptides from Bovine Ligamentum Nuchae proteins hydrolysates: based on sprague-dawley Rat model and molecular docking","volume":"73","author":"Li","year":"2025","journal-title":"J. Agric. Food Chem."},{"issue":"10","key":"10.1016\/j.jep.2026.122064_bib29","doi-asserted-by":"crossref","first-page":"5246","DOI":"10.1002\/jsfa.14247","article-title":"Purification, characterization and protective effects on UVB-induced photoaging in zebrafish of Pleurotus citrinopileatus polysaccharide PCP-2","volume":"105","author":"Li","year":"2025","journal-title":"J. Sci. Food Agric."},{"issue":"Pt 2","key":"10.1016\/j.jep.2026.122064_bib30","article-title":"Isolation and characterization of bioactive collagen peptides from sea bass scales and their anti-photoaging effects","volume":"496","author":"Liu","year":"2025","journal-title":"Food Chem."},{"issue":"2","key":"10.1016\/j.jep.2026.122064_bib31","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s10126-022-10104-4","article-title":"Production of dual inhibitory hydrolysate by enzymatic hydrolysis of squid processing By-product","volume":"24","author":"Liu","year":"2022","journal-title":"Marine biotechnology (New York, N.Y.)"},{"issue":"4","key":"10.1016\/j.jep.2026.122064_bib32","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1038\/s41419-022-04746-4","article-title":"Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle","volume":"13","author":"Lu","year":"2022","journal-title":"Cell Death Dis."},{"issue":"11","key":"10.1016\/j.jep.2026.122064_bib33","doi-asserted-by":"crossref","DOI":"10.3390\/cimb47110895","article-title":"Eleutheroside E ameliorates D-Gal-Induced senescence in human skin fibroblasts through PI3K\/AKT signaling","volume":"47","author":"Ma","year":"2025","journal-title":"Curr. Issues Mol. Biol."},{"issue":"8","key":"10.1016\/j.jep.2026.122064_bib34","first-page":"37","article-title":"Effects of Camel Placenta extract on immune function and macrophage polarization in mice","volume":"55","author":"Mo","year":"2023","journal-title":"Anim. Husb. Vet. Med."},{"issue":"9","key":"10.1016\/j.jep.2026.122064_bib35","doi-asserted-by":"crossref","DOI":"10.3390\/molecules30092026","article-title":"Echinacoside ameliorates UVB-induced skin damage through selective inhibition of the cutaneous TRPV3 channel","volume":"30","author":"Mo","year":"2025","journal-title":"Molecules (Basel, Switzerland)"},{"issue":"7","key":"10.1016\/j.jep.2026.122064_bib37","article-title":"Research progress on the pharmacological effects of animal placentas","volume":"25","author":"Mode","year":"2019","journal-title":"Chin. J. Ethnomed. Ethnopharmacy"},{"issue":"7","key":"10.1016\/j.jep.2026.122064_bib36","article-title":"Research progress on the pharmacological efficacy of animal placentas","volume":"25","author":"MoDe","year":"2019","journal-title":"Journal of Chinese Ethnic Medicine"},{"issue":"2","key":"10.1016\/j.jep.2026.122064_bib38","doi-asserted-by":"crossref","DOI":"10.1002\/hsr2.522","article-title":"Effects of oral administration of equine placental extract supplement on the facial skin of healthy adult women: a randomized, double-blind, placebo-controlled study","volume":"5","author":"Nagae","year":"2022","journal-title":"Health Sci. Rep."},{"issue":"3","key":"10.1016\/j.jep.2026.122064_bib39","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.cardiores.2005.12.002","article-title":"Structure and function of matrix metalloproteinases and TIMPs","volume":"69","author":"Nagase","year":"2006","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.jep.2026.122064_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.ctim.2025.103271","article-title":"Porcine placenta peptides as a complementary functional food for skin rejuvenation: a 12-week randomized, double-blind, placebo-controlled trial","volume":"95","author":"Nguyen","year":"2025","journal-title":"Compl. Ther. Med."},{"key":"10.1016\/j.jep.2026.122064_bib41","doi-asserted-by":"crossref","DOI":"10.1007\/s11357-025-02067-w","article-title":"Facial skin aging: an integrative analysis of genetics, epigenetics, and lifestyle factors","author":"Noroozi","year":"2025","journal-title":"GeroScience"},{"issue":"1","key":"10.1016\/j.jep.2026.122064_bib42","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-27993-9","article-title":"Hydrolysis kinetics amino acid profiling and antioxidant properties of enzymatic hydrolysates from desalted egg white","volume":"15","author":"Rungchang","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.122064_bib43","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.matbio.2025.07.006","article-title":"Collagen diversity in human skin: aging, wound healing, and disorders. Matrix biology","volume":"140","author":"Salamito","year":"2025","journal-title":"journal of the International Society for Matrix Biology"},{"key":"10.1016\/j.jep.2026.122064_bib44","series-title":"The 4th China Camel Conference (2015)","first-page":"7","article-title":"Characteristics and utilization potential of camelid placentas","author":"Si","year":"2015"},{"issue":"22","key":"10.1016\/j.jep.2026.122064_bib45","doi-asserted-by":"crossref","first-page":"13471","DOI":"10.1021\/acs.jafc.4c13160","article-title":"Caffeoylglucaric and caffeoylquinic acids from Inula japonica leaves and their anti-skin aging effects in TNF-\u03b1-Induced normal human fibroblast damage","volume":"73","author":"Son","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2026.122064_bib46","doi-asserted-by":"crossref","DOI":"10.1111\/dom.70463","article-title":"Amino acid metabolism modulates chronic kidney disease progression by mediating the aging process: mechanistic insights and therapeutic interventions","author":"Song","year":"2026","journal-title":"Diabetes Obes. Metabol."},{"issue":"1","key":"10.1016\/j.jep.2026.122064_bib47","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1186\/s13287-025-04460-w","article-title":"Small extracellular vesicles derived from mesenchymal stromal cells loaded with \u03b2-nicotinamide mononucleotide activate NAD(+)\/SIRT3 signaling pathway-mediated mitochondrial autophagy to delay skin aging","volume":"16","author":"Sun","year":"2025","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.jep.2026.122064_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2025.152681","article-title":"A novel polypeptide inhibitor of MMP-1 attenuates the UVA-mediated skin aging","volume":"786","author":"Tang","year":"2025","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"6","key":"10.1016\/j.jep.2026.122064_bib49","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics14061221","article-title":"A novel approach for skin regeneration by a potent bioactive placental-loaded microneedle patch: comparative study of deer, goat, and porcine placentas","volume":"14","author":"Tansathien","year":"2022","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.jep.2026.122064_bib50","doi-asserted-by":"crossref","first-page":"157","DOI":"10.2147\/NSA.S508582","article-title":"Exploring anti-aging potential of dendrobium species and novel microemulsion delivery of dendrobium kentrophyllum extract for anti-aging effect","volume":"18","author":"Thungmungmee","year":"2025","journal-title":"Nanotechnol. Sci. Appl."},{"key":"10.1016\/j.jep.2026.122064_bib51","series-title":"Extraction and Application of Soluble Proteins from Camel Placenta","author":"Tong","year":"2019"},{"issue":"1","key":"10.1016\/j.jep.2026.122064_bib52","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/jidsymp.1998.10","article-title":"Molecular mechanisms of cutaneous aging: connective tissue alterations in the dermis","volume":"3","author":"Uitto","year":"1998","journal-title":"J. Invest. Dermatol. Symp. Proc."},{"issue":"12","key":"10.1016\/j.jep.2026.122064_bib53","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1080\/17460441.2025.2593382","article-title":"Discovery of novel inhibitory peptides on matrix metalloproteinases and elastase for skin antiaging using batch molecular docking strategy","volume":"20","author":"Wang","year":"2025","journal-title":"Expert Opin. Drug Discov."},{"issue":"1","key":"10.1016\/j.jep.2026.122064_bib54","article-title":"Exploring the roles of Polygonati Rhizoma in delaying skin aging using network pharmacology and molecular docking","volume":"16","author":"Wang","year":"2026","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jep.2026.122064_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2025.128285","article-title":"Skin microbiome and skin aging: emerging strategies for manipulation","volume":"300","author":"Wang","year":"2025","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.jep.2026.122064_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2025.147334","article-title":"Effects of ultrasound-assisted non-covalently bound dietary antioxidants on the structure, flavor and digest characteristics of soymilk","volume":"499","author":"Wang","year":"2026","journal-title":"Food Chem."},{"key":"10.1016\/j.jep.2026.122064_bib57","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.freeradbiomed.2025.03.024","article-title":"Imbalanced redox dynamics induce fibroblast senescence leading to impaired stem cell pools and skin aging","volume":"233","author":"Wlaschek","year":"2025","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jep.2026.122064_bib58","article-title":"Study on the effect of Pogostemon cablin Benth on skin aging based on network pharmacology","author":"Wu","year":"2022","journal-title":"Curr. Comput. Aided Drug Des."},{"key":"10.1016\/j.jep.2026.122064_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2026.116212","article-title":"18\u03b2-Glycyrrhetinic acid reduces skin damage from UVB exposure by inhibiting the MyD88\/MAPK signaling pathway","volume":"172","author":"Xie","year":"2026","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2026.122064_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156213","article-title":"Xiyangshen Sanqi Danshen granules attenuated D-gal-induced C57BL\/6J mouse aging through the AMPK\/SIRT1 signaling pathway","volume":"136","author":"Yin","year":"2025","journal-title":"Phytomedicine : international journal of phytotherapy and phytopharmacology"},{"key":"10.1016\/j.jep.2026.122064_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2024.106227","article-title":"Characterization and evaluation of the in vitro and in vivo anti-diabetic activities of camel milk protein hydrolysates derived with different protease digestions","volume":"117","author":"Yu","year":"2024","journal-title":"J. Funct.Foods"},{"issue":"Pt B","key":"10.1016\/j.jep.2026.122064_bib62","article-title":"Chymosin pretreatment accelerated papain catalysed hydrolysis for decreasing casein antigenicity by exposing the cleavage site at tyrosine residues","volume":"404","author":"Zeng","year":"2023","journal-title":"Food Chem."},{"issue":"4","key":"10.1016\/j.jep.2026.122064_bib63","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1039\/C6FO01499B","article-title":"The anti-photoaging effect of antioxidant collagen peptides from silver carp (Hypophthalmichthys molitrix) skin is preferable to tea polyphenols and casein peptides","volume":"8","author":"Zhang","year":"2017","journal-title":"Food Funct."},{"issue":"7","key":"10.1016\/j.jep.2026.122064_bib64","doi-asserted-by":"crossref","DOI":"10.1111\/jocd.70280","article-title":"Efficacy and mechanism of Bazi Bushen Capsule on skin laxity: a combination of clinical and network pharmacology study","volume":"24","author":"Zhao","year":"2025","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.jep.2026.122064_bib65","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2023.1275199","article-title":"Ameliorative effect of black tea extract on the skin of D-galactose-induced aging mice","volume":"10","author":"Zheng","year":"2023","journal-title":"Front. Nutr."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126009189?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126009189?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:47:59Z","timestamp":1785883679000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126009189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":65,"alternative-id":["S0378874126009189"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.122064","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeted discovery of anti-skin aging peptides from Camelus bactrianus placenta: Multi-activity screening, network pharmacology, and in vitro validation focusing on MMP-1 inhibition","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.122064","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"122064"}}