{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T23:11:11Z","timestamp":1790118671979,"version":"4.0.1"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81973592"],"award-info":[{"award-number":["81973592"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82574732"],"award-info":[{"award-number":["82574732"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016067","name":"Shaanxi Administration of Traditional Chinese Medicine","doi-asserted-by":"publisher","award":["2021-GJ-JC004"],"award-info":[{"award-number":["2021-GJ-JC004"]}],"id":[{"id":"10.13039\/100016067","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.jep.2026.122152","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:21:38Z","timestamp":1783009298000},"page":"122152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Taohe Chengqi Decoction ameliorates APID-related local uterine inflammatory injury through modulation of inflammation, oxidative stress, and JNK\/p38 MAPK\u2013NF-\u03baB-related signaling"],"prefix":"10.1016","volume":"371","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5306-4752","authenticated-orcid":false,"given":"Yi-Han","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Chen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Fan","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Jian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing-Tong","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Ping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9199-4124","authenticated-orcid":false,"given":"Yong-Gang","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Yan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.jep.2026.122152_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/ph16071020","article-title":"Recent advances in potential health benefits of quercetin","volume":"16","author":"Aghababaei","year":"2023","journal-title":"Pharmaceuticals"},{"issue":"18","key":"10.1016\/j.jep.2026.122152_bib2","article-title":"Relationship between oxidative stress and endometritis: exploiting knowledge gained in mares and cows","volume":"12","author":"Boni","year":"2022","journal-title":"Animals (Basel)"},{"issue":"5","key":"10.1016\/j.jep.2026.122152_bib3","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1111\/jog.14710","article-title":"The role of mitogen-activated protein kinase signaling pathway in endometriosis","volume":"47","author":"Bora","year":"2021","journal-title":"J. Obstet. Gynaecol. Res."},{"issue":"21","key":"10.1016\/j.jep.2026.122152_bib4","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1056\/NEJMra1411426","article-title":"Pelvic inflammatory disease","volume":"372","author":"Brunham","year":"2015","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jep.2026.122152_bib5","series-title":"Chinese Medicinal Material Images Database","year":"2022"},{"issue":"4","key":"10.1016\/j.jep.2026.122152_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0266144","article-title":"Anti-inflammatory effects of progesterone through NF-\u03baB and MAPK pathway in lipopolysaccharide- or escherichia coli-stimulated bovine endometrial stromal cells","volume":"17","author":"Cui","year":"2022","journal-title":"PLoS One"},{"issue":"12 Suppl. 2","key":"10.1016\/j.jep.2026.122152_bib7","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1093\/infdis\/jiab031","article-title":"Pelvic inflammatory disease due to Neisseria gonorrhoeae and chlamydia trachomatis: immune evasion mechanisms and pathogenic disease pathways","volume":"224","author":"Darville","year":"2021","journal-title":"J. Infect. Dis."},{"issue":"6","key":"10.1016\/j.jep.2026.122152_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19061812","article-title":"Anti-inflammatory effects of resveratrol: mechanistic insights","volume":"19","author":"de S\u00e1 Coutinho","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.jep.2026.122152_bib9","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1007\/s00210-019-01696-1","article-title":"Therapeutic effects of resveratrol in escherichia coli-induced rat endometritis model","volume":"392","author":"Demirel","year":"2019","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"issue":"12","key":"10.1016\/j.jep.2026.122152_bib10","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.23203","volume":"36","author":"Di","year":"2022","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.jep.2026.122152_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2020.575865","article-title":"Analysis of transcriptomic changes in bovine endometrial stromal cells treated with lipopolysaccharide","volume":"7","author":"Ding","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.jep.2026.122152_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.791373","article-title":"Combined intestinal metabolomics and microbiota analysis for acute endometritis induced by lipopolysaccharide in mice","volume":"11","author":"Dong","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"23","key":"10.1016\/j.jep.2026.122152_bib13","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.21037\/atm-21-3345","article-title":"Identifying the clinical presentations, progression, and sequela of pelvic inflammatory disease through physiological, histological and ultrastructural evaluation of a rat animal model","volume":"9","author":"Fan","year":"2021","journal-title":"Ann. Transl. Med."},{"issue":"3","key":"10.1016\/j.jep.2026.122152_bib14","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.ogc.2022.02.019","article-title":"Identification and treatment of acute pelvic inflammatory disease and associated sequelae","volume":"49","author":"Frock-Welnak","year":"2022","journal-title":"Obstet. Gynecol. Clin. N. Am."},{"issue":"3","key":"10.1016\/j.jep.2026.122152_bib15","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.fertnstert.2012.06.021","article-title":"Nuclear factor-kappaB: a main regulator of inflammation and cell survival in endometriosis pathophysiology","volume":"98","author":"Gonz\u00e1lez-Ramos","year":"2012","journal-title":"Fertil. Steril."},{"issue":"2","key":"10.1016\/j.jep.2026.122152_bib16","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1586\/14787210.4.2.235","article-title":"Epidemiology, pathogenesis and treatment of pelvic inflammatory disease","volume":"4","author":"Haggerty","year":"2006","journal-title":"Expert Rev. Anti Infect. Ther."},{"issue":"4","key":"10.1016\/j.jep.2026.122152_bib17","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1210\/en.2008-1379","article-title":"Bacterial lipopolysaccharide induces an endocrine switch from prostaglandin F2alpha to prostaglandin E2 in bovine endometrium","volume":"150","author":"Herath","year":"2009","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.jep.2026.122152_bib18","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1002\/ptr.7464","article-title":"Impact of curcumin, quercetin, or resveratrol on the pathophysiology of endometriosis: a systematic review","volume":"36","author":"Hip\u00f3lito-Reis","year":"2022","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2026.122152_bib19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13020-017-0128-y","article-title":"The neuroprotective effects of Tao-Ren-Cheng-Qi Tang against embolic stroke in rats","volume":"12","author":"Hsu","year":"2017","journal-title":"Chin. Med."},{"key":"10.1016\/j.jep.2026.122152_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2020.582520","article-title":"A systematic Study of mechanism of Sargentodoxa cuneata and Patrinia scabiosifolia against pelvic inflammatory disease with dampness-heat stasis syndrome via network pharmacology approach","volume":"11","author":"Hu","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.122152_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120057","article-title":"Integrating network pharmacology and transcriptomics reveals that bushen huoxue recipe ameliorates ferroptosis and apoptosis in granulosa cells by regulating PI3K\/Akt signaling pathway in premature ovarian insufficiency mice","volume":"351","author":"Huang","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.122152_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2022.103751","article-title":"Enhanced expression of miR-26a ameliorates lipopolysaccharide-induced endometritis by targeting MAP3K8 to inactivate MAPK signaling pathway","volume":"154","author":"Huang","year":"2022","journal-title":"J. Reprod. Immunol."},{"issue":"4","key":"10.1016\/j.jep.2026.122152_bib23","doi-asserted-by":"crossref","first-page":"215","DOI":"10.31128\/AJGP-09-22-6576","article-title":"Pelvic inflammatory disease and infertility","volume":"52","author":"Hunt","year":"2023","journal-title":"Aust J Gen Pract"},{"key":"10.1016\/j.jep.2026.122152_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.anireprosci.2024.107460","article-title":"Analysis of blood biochemistry and non-targeted metabolomics of endometritis in dairy cows","volume":"264","author":"Ji","year":"2024","journal-title":"Anim. Reprod. Sci."},{"issue":"2","key":"10.1016\/j.jep.2026.122152_bib25","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1089\/jir.2016.0058","article-title":"IFN-\u03c4 plays an anti-inflammatory role in staphylococcus aureus-Induced endometritis in mice through the suppression of NF-\u03baB pathway and MMP9 expression","volume":"37","author":"Jiang","year":"2017","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.jep.2026.122152_bib26","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.micpath.2018.06.031","article-title":"Protective effects of apigenin on LPS-induced endometritis via activating Nrf2 signaling pathway","volume":"123","author":"Jiang","year":"2018","journal-title":"Microb. Pathog."},{"issue":"3","key":"10.1016\/j.jep.2026.122152_bib27","first-page":"479","article-title":"Integration strategy of network pharmacology in Traditional Chinese Medicine: a narrative review","volume":"42","author":"Jiashuo","year":"2022","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.jep.2026.122152_bib28","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.jnutbio.2019.05.003","article-title":"Naringenin ameliorates progression of endometriosis by modulating Nrf2\/Keap1\/HO1 axis and inducing apoptosis in rats","volume":"70","author":"Kapoor","year":"2019","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.jep.2026.122152_bib29","doi-asserted-by":"crossref","first-page":"2710","DOI":"10.3389\/fimmu.2018.02710","article-title":"Pathogenesis of Neisseria gonorrhoeae and the host defense in ascending infections of human fallopian tube","volume":"9","author":"Lenz","year":"2018","journal-title":"Front. Immunol."},{"issue":"1\u20133","key":"10.1016\/j.jep.2026.122152_bib30","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ejphar.2013.02.021","article-title":"Emodin ameliorates lipopolysaccharide-induced mastitis in mice by inhibiting activation of NF-\u03baB and MAPKs signal pathways","volume":"705","author":"Li","year":"2013","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2026.122152_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113684","article-title":"Ainsliaea fragrans champ. Extract prevents cervicitis in BALB\/c mice and regulates MyD88-NF-\u03baB signaling pathway in MALP-2-stimulated RAW264.7 cells","volume":"269","author":"Lin","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.122152_bib32","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.molimm.2021.07.015","article-title":"Live S. aureus and heat-killed S. aureus induce different inflammation-associated factors in bovine endometrial tissue in vitro","volume":"139","author":"Liu","year":"2021","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.jep.2026.122152_bib33","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6620124","article-title":"Study on the bioassay of anti-inflammatory effects of fuke qianjin capsule based on COX-2 inhibiting activity","volume":"2021","author":"Ma","year":"2021","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.jep.2026.122152_bib34","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/1744754","article-title":"Enhanced expression of miR-34a enhances Escherichia coli lipopolysaccharide-mediated endometritis by targeting LGR4 to activate the NF-\u03baB pathway","volume":"2021","author":"Ma","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"3","key":"10.1016\/j.jep.2026.122152_bib35","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/humupd\/dmv060","article-title":"Kinase signalling pathways in endometriosis: potential targets for non-hormonal therapeutics","volume":"22","author":"McKinnon","year":"2016","journal-title":"Hum. Reprod. Update"},{"issue":"11","key":"10.1016\/j.jep.2026.122152_bib36","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1038\/cdd.2014.123","article-title":"TAK1 control of cell death","volume":"21","author":"Mihaly","year":"2014","journal-title":"Cell Death Differ."},{"issue":"8","key":"10.1016\/j.jep.2026.122152_bib37","doi-asserted-by":"crossref","first-page":"4075","DOI":"10.1002\/ptr.7071","article-title":"A review on the protective effects of naringenin against natural and chemical toxic agents","volume":"35","author":"Naraki","year":"2021","journal-title":"Phytother Res."},{"issue":"3","key":"10.1016\/j.jep.2026.122152_bib38","doi-asserted-by":"crossref","first-page":"413","DOI":"10.4142\/jvs.2016.17.3.413","article-title":"Establishment of hydrochloric acid\/lipopolysaccharide-induced pelvic inflammatory disease model","volume":"17","author":"Oh","year":"2016","journal-title":"J. Vet. Sci."},{"key":"10.1016\/j.jep.2026.122152_bib39","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jnutbio.2018.09.024","article-title":"Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo","volume":"63","author":"Park","year":"2019","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.jep.2026.122152_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1144323","article-title":"Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: a randomized, triple-blind placebo-controlled clinical trial","volume":"14","author":"Rostami","year":"2023","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.jep.2026.122152_bib41","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1287321","article-title":"A randomized, double-blind, positive-controlled, Phase-II clinical trial to evaluate efficacy and safety of Fuke Qianjin capsule in Pakistani patients with pelvic inflammatory disease","volume":"15","author":"Shah","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.122152_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113555","article-title":"Recent advances in the therapeutic potential of emodin for human health","volume":"154","author":"Sharifi-Rad","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"8","key":"10.1016\/j.jep.2026.122152_bib43","first-page":"972","article-title":"Influence of fuke qianjin tablets on ICAM-1 and MMP-2 in acute pelvic inflammatory models of rats","volume":"31","author":"Shi","year":"2012","journal-title":"Herald of Medicine"},{"key":"10.1016\/j.jep.2026.122152_bib44","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1186\/1472-6882-14-372","article-title":"Dohaekseunggi-tang extract inhibits obesity, hyperlipidemia, and hypertension in high-fat diet-induced obese mice","volume":"14","author":"Sung","year":"2014","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.jep.2026.122152_bib45","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/561909","article-title":"Treatment of acute pelvic inflammatory disease","volume":"2011","author":"Sweet","year":"2011","journal-title":"Infect. Dis. Obstet. Gynecol."},{"key":"10.1016\/j.jep.2026.122152_bib46","doi-asserted-by":"crossref","first-page":"9094","DOI":"10.12659\/MSM.916070","article-title":"Comparison of the analgesic and anti-inflammatory effects of Xiaoyuningkun decoction with Cynanchum paniculatum and fukeqianjin in a mouse model of pelvic inflammatory disease","volume":"25","author":"Tang","year":"2019","journal-title":"Med. Sci. Monit."},{"issue":"2","key":"10.1016\/j.jep.2026.122152_bib47","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1093\/biolre\/ioz187","article-title":"Protective effects of astaxanthin on lipopolysaccharide-induced inflammation in bovine endometrial epithelial cells","volume":"102","author":"Wan","year":"2020","journal-title":"Biol. Reprod."},{"issue":"2","key":"10.1016\/j.jep.2026.122152_bib48","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24020373","article-title":"Protective effects of astragaloside IV against LPS-Induced endometritis in mice through inhibiting activation of the NF-\u03baB, p38 and JNK signaling pathways","volume":"24","author":"Wang","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.jep.2026.122152_bib49","first-page":"135","article-title":"Historical evolution and textual research on classical prescription taohe chengqitang","author":"Wang","year":"2022","journal-title":"Chin. J. Exp. Tradit. Med. Formulae"},{"issue":"5","key":"10.1016\/j.jep.2026.122152_bib50","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1007\/s10753-018-0814-7","article-title":"Luteoloside protects the uterus from staphylococcus aureus-Induced inflammation, apoptosis, and injury","volume":"41","author":"Wang","year":"2018","journal-title":"Inflammation"},{"issue":"4","key":"10.1016\/j.jep.2026.122152_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr7004a1","article-title":"Sexually transmitted infections treatment guidelines, 2021","volume":"70","author":"Workowski","year":"2021","journal-title":"MMWR Recomm. Rep. (Morb. Mortal. Wkly. Rep.)"},{"key":"10.1016\/j.jep.2026.122152_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118659","article-title":"Luoshi neiyi Prescription inhibits estradiol synthesis and inflammation in endometriosis through the HIF1A\/EZH2\/SF-1 pathway","volume":"335","author":"Wu","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"Pt 3","key":"10.1016\/j.jep.2026.122152_bib53","article-title":"FuKe QianJin capsule alleviates endometritis via inhibiting inflammation and pyroptosis through modulating TLR4\/NF-\u03baB\/NLRP3 pathway","volume":"337","author":"Xiong","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.122152_bib54","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00409-23","article-title":"Uterine tissue metabonomics combined with 16S rRNA gene sequencing to analyze the changes of gut Microbiota in mice with endometritis and the intervention effect of tau interferon","volume":"11","author":"Xue","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.jep.2026.122152_bib55","article-title":"Metabolic Insight into the neuroprotective effect of tao-he-cheng-qi (THCQ) decoction on ICH rats using untargeted metabolomics","volume":"12","author":"Yang","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"9","key":"10.1016\/j.jep.2026.122152_bib56","first-page":"1075","article-title":"Research of the intervention of Taohechengqi Decoction on model rats with acute pelvic inflammatory disease through JAK2\/STAT1 signal pathway","volume":"19","author":"Yang","year":"2019","journal-title":"Evaluation and Analysis of Drug-Use in Hospitals of China"},{"issue":"8","key":"10.1016\/j.jep.2026.122152_bib57","doi-asserted-by":"crossref","first-page":"915","DOI":"10.2174\/156800909790192383","article-title":"Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascades","volume":"9","author":"Yang","year":"2009","journal-title":"Curr. Cancer Drug Targets"},{"issue":"15","key":"10.1016\/j.jep.2026.122152_bib59","first-page":"135","article-title":"Effect of modified taohe chengqi decoction combined with thunder-fire moxibustion in the treatment of acute pelvic inflammatory disease and its influence on serum inflammatory indexes","volume":"21","author":"Yi","year":"2024","journal-title":"China Medical. Innovation"},{"key":"10.1016\/j.jep.2026.122152_bib58","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.rvsc.2019.08.018","article-title":"Ferulic acid inhibits bovine endometrial epithelial cells against LPS-induced inflammation via suppressing NF-\u03baB and MAPK pathway","volume":"126","author":"Yin","year":"2019","journal-title":"Res. Vet. Sci."},{"issue":"3","key":"10.1016\/j.jep.2026.122152_bib60","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24032901","article-title":"The role of NF-\u03baB in endometrial diseases in humans and animals: a review","volume":"24","author":"Zdrojkowski","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jep.2026.122152_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113051","article-title":"Revealing active ingredients, potential targets, and action mechanism of Ermiao fang for treating endometritis based on network pharmacology strategy","volume":"260","author":"Zhang","year":"2020","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.122152_bib62","article-title":"Network pharmacology: a new approach for chinese herbal medicine research","volume":"2013","author":"Zhang","year":"2013","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"5","key":"10.1016\/j.jep.2026.122152_bib63","first-page":"1376","article-title":"Effect of Fu yan qing prescription on pelvic effusion, mass absorption and microenvironment of pelvic blood stasis in patients with sequelae of pelvic inflammatory disease of accumulation of dampness heat and blood stasis type","volume":"38","author":"Zhang","year":"2022","journal-title":"Pakistan J. Med. Sci."},{"key":"10.1016\/j.jep.2026.122152_bib64","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s13020-018-0217-6","article-title":"Metabonomic study of the protective effect of fukeqianjin formula on multi-pathogen induced pelvic inflammatory disease in rats","volume":"13","author":"Zhang","year":"2018","journal-title":"Chin. Med."},{"issue":"3","key":"10.1016\/j.jep.2026.122152_bib65","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s10753-014-0106-9","article-title":"Selenium deficiency facilitates inflammation through the regulation of TLR4 and TLR4-Related signaling pathways in the mice uterus","volume":"38","author":"Zhang","year":"2015","journal-title":"Inflammation"},{"key":"10.1016\/j.jep.2026.122152_bib66","article-title":"IFN-\u03c4 displays anti-inflammatory effects on Staphylococcus aureus endometritis via inhibiting the activation of the NF-\u03baB and MAPK pathways in mice","volume":"2017","author":"Zhang","year":"2017","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.jep.2026.122152_bib67","article-title":"Anticolon cancer targets and molecular mechanisms of tao-he-cheng-qi formula","volume":"2022","author":"Zhang","year":"2022","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.jep.2026.122152_bib69","series-title":"Shang Han Lun: on Cold Damage, Translation and Commentaries","author":"Zhang","year":"1999"},{"key":"10.1016\/j.jep.2026.122152_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.fitote.2026.107234","article-title":"The mechanism of taohe chengqi decoction in modulating inflammation and alleviating cerebral ischemia-reperfusion injury in rats through regulation of the arachidonic acid metabolism pathway and PI3K\/AKT\/HIF-1\u03b1 signaling pathway","volume":"191","author":"Zhang","year":"2026","journal-title":"Fitoterapia"},{"issue":"4","key":"10.1016\/j.jep.2026.122152_bib70","first-page":"405","article-title":"Application analysis of animal models for pelvic inflammatory disease based on data mining","volume":"44","author":"Zheng","year":"2024","journal-title":"Lab. Anim. Comp. Med."},{"key":"10.1016\/j.jep.2026.122152_bib71","doi-asserted-by":"crossref","first-page":"425","DOI":"10.3389\/fphar.2020.00425","article-title":"Deciphering the pharmacological mechanisms of taohe-chengqi decoction extract against renal fibrosis through integrating network pharmacology and experimental validation in vitro and in vivo","volume":"11","author":"Zhou","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.122152_bib72","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.rvsc.2015.04.004","article-title":"Sodium houttuyfonate inhibits inflammation by blocking the MAPKs\/NF-\u03baB signaling pathways in bovine endometrial epithelial cells","volume":"100","author":"Zhu","year":"2015","journal-title":"Res. Vet. Sci."},{"issue":"9","key":"10.1016\/j.jep.2026.122152_bib73","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.tim.2016.05.007","article-title":"Chlamydia trachomatis genital tract infections: when host immune response and the microbiome collide","volume":"24","author":"Ziklo","year":"2016","journal-title":"Trends Microbiol."}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126010068?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378874126010068?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T23:51:34Z","timestamp":1785973894000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378874126010068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":73,"alternative-id":["S0378874126010068"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.122152","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Taohe Chengqi Decoction ameliorates APID-related local uterine inflammatory injury through modulation of inflammation, oxidative stress, and JNK\/p38 MAPK\u2013NF-\u03baB-related signaling","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.122152","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"122152"}}