{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:01:28Z","timestamp":1790776888568,"version":"4.1.0"},"reference-count":190,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ethnopharmacology"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.jep.2026.122187","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:57:53Z","timestamp":1784044673000},"page":"122187","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Short-chain fatty acid metabolism in acute lung injury and intervention strategies from traditional Chinese medicine"],"prefix":"10.1016","volume":"372","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1726-1471","authenticated-orcid":false,"given":"Bing","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongrong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangnan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaya","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lumei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yitong","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghui","family":"Xiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzheng","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jep.2026.122187_bib1","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.semcancer.2019.08.029","article-title":"Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy","volume":"69","author":"Aiello","year":"2021","journal-title":"Semin. Cancer Biol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.clinthera.2025.07.009","article-title":"Assessing the role of cannabis in managing spasticity in multiple sclerosis: a systematic review and meta-analysis","volume":"48","author":"AlHabil","year":"2026","journal-title":"Clin. Ther."},{"issue":"12","key":"10.1016\/j.jep.2026.122187_bib3","doi-asserted-by":"crossref","first-page":"3961","DOI":"10.1080\/10408398.2022.2137776","article-title":"Beneficial effects of butyrate on brain functions: a view of epigenetic","volume":"64","author":"Alpino","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.jep.2026.122187_bib4","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/7299778","article-title":"Potential therapeutic applications of plant-derived alkaloids against inflammatory and neurodegenerative diseases","volume":"2022","author":"Aryal","year":"2022","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.jep.2026.122187_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2022.110231","article-title":"Short chain fatty acids: fundamental mediators of the gut-lung axis and their involvement in pulmonary diseases","volume":"368","author":"Ashique","year":"2022","journal-title":"Chem. Biol. Interact."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib6","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00210-024-03392-1","article-title":"Crosstalk between ROS-inflammatory gene expression axis in the progression of lung disorders","volume":"398","author":"Ashique","year":"2025","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"issue":"11","key":"10.1016\/j.jep.2026.122187_bib7","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1001\/jama.2022.2017","article-title":"Association of COVID-19 acute respiratory distress syndrome with symptoms of posttraumatic stress disorder in family members after ICU discharge","volume":"327","author":"Azoulay","year":"2022","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.jep.2026.122187_bib8","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s00134-024-07396-6","article-title":"One-year outcomes in acute respiratory distress syndrome survivors: COVID-19 versus seasonal influenza or pneumonia","volume":"50","author":"Azoulay","year":"2024","journal-title":"Intensive Care Med."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib9","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S2213-2600(21)00157-0","article-title":"Advancing precision medicine for acute respiratory distress syndrome","volume":"10","author":"Beitler","year":"2022","journal-title":"Lancet Respir. Med."},{"issue":"8","key":"10.1016\/j.jep.2026.122187_bib10","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1001\/jama.2016.0291","article-title":"Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries","volume":"315","author":"Bellani","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jep.2026.122187_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2024.1371064","article-title":"A synbiotic mixture of Bifidobacterium breve M16-V, oligosaccharides and pectin, enhances short chain fatty acid production and improves lung health in a preclinical model for pulmonary neutrophilia","volume":"11","author":"Bezemer","year":"2024","journal-title":"Front. Nutr."},{"issue":"3","key":"10.1016\/j.jep.2026.122187_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/antiox12030548","article-title":"Oxidative stress and inflammation in acute and chronic lung injuries","volume":"12","author":"Bezerra","year":"2023","journal-title":"Antioxidants"},{"issue":"10358","key":"10.1016\/j.jep.2026.122187_bib13","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/S0140-6736(22)01485-4","article-title":"Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes","volume":"400","author":"Bos","year":"2022","journal-title":"Lancet"},{"issue":"16","key":"10.1016\/j.jep.2026.122187_bib14","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.00829-17","article-title":"Heterologous expression of the Clostridium carboxidivorans CO dehydrogenase alone or together with the acetyl coenzyme A synthase enables both reduction of CO(2) and oxidation of CO by Clostridium acetobutylicum","volume":"83","author":"Carlson","year":"2017","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.jep.2026.122187_bib15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/978-3-319-68483-3_4","article-title":"Pulmonary endothelial cell apoptosis in emphysema and acute lung injury","volume":"228","author":"Chambers","year":"2018","journal-title":"Adv. Anat. Embryol. Cell Biol."},{"key":"10.1016\/j.jep.2026.122187_bib16","doi-asserted-by":"crossref","first-page":"803","DOI":"10.2147\/JIR.S303105","article-title":"Sodium propionate enhances Nrf2-Mediated protective defense against oxidative stress and inflammation in lipopolysaccharide-induced neonatal mice","volume":"14","author":"Chen","year":"2021","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.jep.2026.122187_bib17","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13020-015-0039-8","article-title":"Qing-Yi decoction in participants with severe acute pancreatitis: a randomized controlled trial","volume":"10","author":"Chen","year":"2015","journal-title":"Chin. Med."},{"issue":"9","key":"10.1016\/j.jep.2026.122187_bib18","doi-asserted-by":"crossref","DOI":"10.3390\/nu16091376","article-title":"Analysis of the protective effects of rosa roxburghii-Fermented juice on lipopolysaccharide-induced acute lung injury in mice through network pharmacology and metabolomics","volume":"16","author":"Chen","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.jep.2026.122187_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1447735","article-title":"Rosa roxburghii fermented juice mitigates LPS-induced acute lung injury by modulation of intestinal flora and metabolites","volume":"15","author":"Chen","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jep.2026.122187_bib20","article-title":"Bear bile powder ameliorates LPS-induced acute lung injury by inhibiting CD14 pathway and improving intestinal flora: exploration of \"Fei (Lung)-Dachang (Large Intestine) Interaction\"","author":"Cheng","year":"2024","journal-title":"Chin. J. Integr. Med."},{"issue":"24","key":"10.1016\/j.jep.2026.122187_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/nu14245231","article-title":"A high-fiber diet or dietary supplementation of acetate attenuate hyperoxia-induced acute lung injury","volume":"14","author":"Chu","year":"2022","journal-title":"Nutrients"},{"issue":"27","key":"10.1016\/j.jep.2026.122187_bib22","article-title":"The effect of anti-dementia drugs on Alzheimer disease-induced cognitive impairment: a network meta-analysis","volume":"98","author":"Cui","year":"2019","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.jep.2026.122187_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2025.111677","article-title":"N-acyl hydrazone derivatives reduce pro-inflammatory cytokines, iNOS and COX-2 in acute lung inflammation model","volume":"420","author":"de Lima Porto Ramos","year":"2025","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jep.2026.122187_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.114111","article-title":"Regulated programmed cell death in sepsis associated acute lung injury: from pathogenesis to therapy","volume":"148","author":"Deng","year":"2025","journal-title":"Int. Immunopharmacol."},{"issue":"5","key":"10.1016\/j.jep.2026.122187_bib25","first-page":"1319","article-title":"[Effects of total ginsenosides from Panax ginseng stems and leaves on gut microbiota and short-chain fatty acids metabolism in acute lung injury mice]","volume":"48","author":"Ding","year":"2023","journal-title":"Zhongguo Zhongyao Zazhi"},{"key":"10.1016\/j.jep.2026.122187_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114052","article-title":"Safety, tolerability, pharmacokinetics, and food effect of baicalein tablets in healthy Chinese subjects: a single-center, randomized, double-blind, placebo-controlled, single-dose phase I study","volume":"274","author":"Dong","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"42","key":"10.1016\/j.jep.2026.122187_bib27","doi-asserted-by":"crossref","first-page":"3322","DOI":"10.2174\/0113816128319149240812103715","article-title":"Network pharmacology analysis and retrospective cohort study revealing the effect of qingyi decoction on intestinal paralysis in patients with severe acute pancreatitis","volume":"30","author":"Du","year":"2024","journal-title":"Curr. Pharm. Des."},{"issue":"13","key":"10.1016\/j.jep.2026.122187_bib28","doi-asserted-by":"crossref","first-page":"7379","DOI":"10.3390\/ijms25137379","article-title":"The Role of Short Chain Fatty Acids in Inflammation and Body Health","volume":"25","author":"Du","year":"2024","journal-title":"International Journal of Molecular Sciences"},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib29","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.immuni.2024.01.002","article-title":"Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity","volume":"57","author":"Eshleman","year":"2024","journal-title":"Immunity"},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib30","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.tim.2023.07.014","article-title":"Beyond butyrate: microbial fiber metabolism supporting colonic epithelial homeostasis","volume":"32","author":"Fagundes","year":"2024","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.jep.2026.122187_bib31","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jare.2024.01.003","article-title":"Rare ginsenosides: a unique perspective of ginseng research","volume":"66","author":"Fan","year":"2024","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.jep.2026.122187_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1277102","article-title":"The role of intestinal microbes on intestinal barrier function and host immunity from a metabolite perspective","volume":"14","author":"Fu","year":"2023","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib33","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1208\/s12248-008-9022-y","article-title":"Sodium-coupled monocarboxylate transporters in normal tissues and in cancer","volume":"10","author":"Ganapathy","year":"2008","journal-title":"AAPS J."},{"key":"10.1016\/j.jep.2026.122187_bib34","article-title":"Modulatory effects of huoxiang zhengqi oral liquid on gut microbiome homeostasis based on healthy adults and antibiotic-induced gut microbial dysbiosis mice model","volume":"13","author":"Gao","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.156436","article-title":"Unveiling polysaccharides of Houttuynia cordata Thunb.: extraction, purification, structure, bioactivities, and structure-activity relationships","volume":"138","author":"Gao","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jep.2026.122187_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116876","article-title":"Butyrate improves recovery from experimental necrotizing enterocolitis by metabolite hesperetin through potential inhibition the PI3K-Akt pathway","volume":"176","author":"Gao","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2026.122187_bib37","article-title":"Cell origin and iNOS function are critical to macrophage activation following acute lung injury","volume":"12","author":"Golden","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.102165","article-title":"Short-chain fatty acids as modulators of redox signaling in health and disease","volume":"47","author":"Gonzalez-Bosch","year":"2021","journal-title":"Redox Biol."},{"issue":"Pt A","key":"10.1016\/j.jep.2026.122187_bib39","article-title":"Jingfang granule alleviates Pseudomonas aeruginosa-induced acute lung inflammation through suppression of STAT3\/IL-17\/NF-kappaB pathway based on network pharmacology analysis and experimental validation","volume":"318","author":"Gu","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"6","key":"10.1016\/j.jep.2026.122187_bib40","doi-asserted-by":"crossref","DOI":"10.1111\/apha.70051","article-title":"Sodium-coupled monocarboxylate absorption in the airway epithelium is facilitated by the SLC5A8 Co-Transporter","volume":"241","author":"Guequen","year":"2025","journal-title":"Acta Physiol."},{"key":"10.1016\/j.jep.2026.122187_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155859","article-title":"Polygala tenuifolia willd. Extract alleviates LPS-induced acute lung injury in rats via TLR4\/NF-\u03baB pathway and NLRP3 inflammasome suppression","volume":"132","author":"Guo","year":"2024","journal-title":"Phytomedicine"},{"issue":"24","key":"10.1016\/j.jep.2026.122187_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/nu16244374","article-title":"Effects of the ketogenic diet on microbiota composition and short-chain fatty acids in women with overweight\/obesity","volume":"16","author":"G\u00fczey Akansel","year":"2024","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib43","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2281011","article-title":"Butyrate reduces adherent-invasive E. Coli-evoked disruption of epithelial mitochondrial morphology and barrier function: involvement of free fatty acid receptor 3","volume":"15","author":"Hamed","year":"2023","journal-title":"Gut Microbes"},{"key":"10.1016\/j.jep.2026.122187_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.110432","article-title":"A purified membrane protein from Akkermansia muciniphila blunted the sepsis-induced acute lung injury by modulation of gut microbiota in rats","volume":"121","author":"Han","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib45","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12944-018-0797-2","article-title":"Baicalin reduces blood lipids and inflammation in patients with coronary artery disease and rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial","volume":"17","author":"Hang","year":"2018","journal-title":"Lipids Health Dis."},{"issue":"11","key":"10.1016\/j.jep.2026.122187_bib46","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1007\/s13205-024-04130-3","article-title":"Sodium propionate ameliorates lipopolysaccharide-induced acute respiratory distress syndrome in rats via the PI3K\/AKT\/mTOR signaling pathway","volume":"14","author":"He","year":"2024","journal-title":"3 Biotech"},{"key":"10.1016\/j.jep.2026.122187_bib47","article-title":"Tanreqing injection attenuates macrophage activation and the inflammatory response via the lncRNA-SNHG1\/HMGB1 axis in lipopolysaccharide-induced acute lung injury","volume":"13","author":"Hu","year":"2022","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib48","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1186\/s12967-024-05376-4","article-title":"Gut microbiota-derived acetate attenuates lung injury induced by influenza infection via protecting airway tight junctions","volume":"22","author":"Hu","year":"2024","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.jep.2026.122187_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.156049","article-title":"Baicalein ameliorates SEB-induced acute respiratory distress syndrome in a microbiota-dependent manner","volume":"135","author":"Hu","year":"2024","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib50","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1093\/cei\/uxab028","article-title":"The effect of short-chain fatty acids on M2 macrophages polarization in vitro and in vivo","volume":"207","author":"Huang","year":"2022","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.jep.2026.122187_bib51","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jpba.2018.02.020","article-title":"Structural characterization and discrimination of Chimonanthus nitens Oliv. leaf from different geographical origins based on multiple chromatographic analysis combined with chemometric methods","volume":"154","author":"Huang","year":"2018","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jep.2026.122187_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.109136","article-title":"Acetate, a gut bacterial product, ameliorates ischemia-reperfusion induced acute lung injury in rats","volume":"111","author":"Hung","year":"2022","journal-title":"Int. Immunopharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.122187_bib53","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/s41579-024-01106-1","article-title":"Akkermansia muciniphila: biology, microbial ecology, host interactions and therapeutic potential","volume":"23","author":"Ioannou","year":"2025","journal-title":"Nat. Rev. Microbiol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib54","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1021\/acs.molpharmaceut.9b00872","article-title":"5-Aminosalicylic acid azo-coupled with a GPR109A agonist is a colon-targeted anticolitic codrug with a reduced risk of skin toxicity","volume":"17","author":"Jeong","year":"2020","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jep.2026.122187_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115640","article-title":"Biotransformed bear bile powder ameliorates diet-induced nonalcoholic steatohepatitis in mice through modulating arginine biosynthesis via FXR\/PXR-PI3K-AKT-NOS3 axis","volume":"168","author":"Jiang","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2026.122187_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116232","article-title":"Elsholtzia bodinieri Vaniot ameliorated acute lung injury in mice by regulating pyroptosis, inflammation, oxidative stress and macrophage polarization","volume":"307","author":"Jiang","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib57","doi-asserted-by":"crossref","first-page":"5573","DOI":"10.2147\/DDDT.S487315","article-title":"The Clinical Efficacy of Gegen Qinlian Decoction in Treating Type 2 Diabetes is Positively Correlated with the Dose of Coptidis rhizoma: three Randomized, Doubleblind, Dose-Parallel Controlled Clinical Trials","volume":"18","author":"Kang","year":"2024","journal-title":"Drug Des. Dev. Ther."},{"issue":"6","key":"10.1016\/j.jep.2026.122187_bib58","doi-asserted-by":"crossref","DOI":"10.3390\/children12060695","article-title":"Propolis as a treatment option for hand, foot, and mouth disease (HFMD) in children: a prospective randomized clinical study","volume":"12","author":"Kara","year":"2025","journal-title":"Children"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib59","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1046\/j.1472-8206.2003.00117.x","article-title":"A clinical pharmacological study of the potential beneficial effects of a propolis food product as an adjuvant in asthmatic patients","volume":"17","author":"Khayyal","year":"2003","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajcnut.2025.10.001","article-title":"Preoperative plasma short- and branched-chain fatty acids in relation to risk of complications after colorectal cancer surgery: a prospective cohort study","author":"Klaassen-Dekker","year":"2025","journal-title":"Am. J. Clin. Nutr."},{"issue":"6","key":"10.1016\/j.jep.2026.122187_bib61","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.cell.2016.05.041","article-title":"From dietary fiber to host physiology: Short-Chain fatty acids as key bacterial metabolites","volume":"165","author":"Koh","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.jep.2026.122187_bib62","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.755845","article-title":"Distinct effects of short chain fatty acids on host energy balance and fuel homeostasis with focus on route of administration and host species","volume":"15","author":"Kong","year":"2021","journal-title":"Front. Neurosci."},{"issue":"12","key":"10.1016\/j.jep.2026.122187_bib63","doi-asserted-by":"crossref","DOI":"10.3390\/nu15122760","article-title":"Butyrate protects barrier integrity and suppresses immune activation in a Caco-2\/PBMC Co-Culture model while HDAC inhibition mimics butyrate in restoring cytokine-induced barrier disruption","volume":"15","author":"Korsten","year":"2023","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib64","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1002\/ptr.8047","article-title":"The influence of propolis plus Hyoscyamus niger L. against COVID-19: a phase II, multicenter, placebo-controlled, randomized trial","volume":"38","author":"Kosari","year":"2024","journal-title":"Phytother Res."},{"key":"10.1016\/j.jep.2026.122187_bib65","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1360370","article-title":"Alveolar-capillary endocytosis and trafficking in acute lung injury and acute respiratory distress syndrome","volume":"15","author":"Kryvenko","year":"2024","journal-title":"Front. Immunol."},{"issue":"13","key":"10.1016\/j.jep.2026.122187_bib66","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.2174\/0118715303262653231120043819","article-title":"Molecular targets of valeric acid: a bioactive natural product for endocrine, metabolic, and immunological disorders","volume":"24","author":"Kumari","year":"2024","journal-title":"Endocr. Metab. Immune Disord. Drug Targets"},{"issue":"8","key":"10.1016\/j.jep.2026.122187_bib67","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25084276","article-title":"Preventive effect of the total polyphenols from Nymphaea candida on sepsis-induced acute lung injury in mice via Gut Microbiota and NLRP3, TLR-4\/NF-kappaB pathway","volume":"25","author":"Li","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.jep.2026.122187_bib68","first-page":"783","article-title":"[Regulating effects of Rosa roxburghii tratt preparation on immune function in arseniasis patients caused by coal burning]","volume":"47","author":"Li","year":"2013","journal-title":"Zhonghua Yufang Yixue Zazhi"},{"key":"10.1016\/j.jep.2026.122187_bib69","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.ijbiomac.2019.10.010","article-title":"Protective effect of Ganoderma atrum polysaccharides in acute lung injury rats and its metabolomics","volume":"142","author":"Li","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jep.2026.122187_bib70","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.intimp.2018.01.017","article-title":"Sodium butyrate alleviates LPS-induced acute lung injury in mice via inhibiting HMGB1 release","volume":"56","author":"Li","year":"2018","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib71","article-title":"Integrated Pharmacology Reveals the Molecular Mechanism of Gegen Qinlian Decoction Against Lipopolysaccharide-induced Acute Lung Injury","volume":"13","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"21","key":"10.1016\/j.jep.2026.122187_bib72","doi-asserted-by":"crossref","first-page":"12072","DOI":"10.1021\/acs.jafc.3c08385","article-title":"Ganoderma lucidum polysaccharide supplementation significantly activates T-Cell-Mediated antitumor immunity and enhances Anti-PD-1 immunotherapy efficacy in colorectal cancer","volume":"72","author":"Li","year":"2024","journal-title":"J. Agric. Food Chem."},{"issue":"11","key":"10.1016\/j.jep.2026.122187_bib73","doi-asserted-by":"crossref","DOI":"10.3390\/nu16111598","article-title":"Propolis alleviates acute lung injury induced by heat-inactivated methicillin-resistant Staphylococcus aureus via regulating inflammatory mediators, Gut Microbiota and serum metabolites","volume":"16","author":"Li","year":"2024","journal-title":"Nutrients"},{"issue":"7","key":"10.1016\/j.jep.2026.122187_bib74","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0068786","article-title":"Sodium butyrate protects against severe burn-induced remote acute lung injury in rats","volume":"8","author":"Liang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jep.2026.122187_bib75","doi-asserted-by":"crossref","first-page":"554","DOI":"10.3389\/fimmu.2015.00554","article-title":"Redirection of epithelial immune responses by short-chain fatty acids through inhibition of histone deacetylases","volume":"6","author":"Lin","year":"2015","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib76","doi-asserted-by":"crossref","DOI":"10.1080\/21688370.2021.1883965","article-title":"Airway tight junctions as targets of viral infections","volume":"9","author":"Linfield","year":"2021","journal-title":"Tissue Barriers"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib77","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1186\/s12967-025-06994-2","article-title":"Acute lung injury: pathogenesis and treatment","volume":"23","author":"Liu","year":"2025","journal-title":"J. Transl. Med."},{"issue":"6","key":"10.1016\/j.jep.2026.122187_bib78","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1021\/acs.jafc.8b06359","article-title":"Sodium butyrate inhibits the inflammation of lipopolysaccharide-induced acute lung injury in mice by regulating the toll-like receptor 4\/Nuclear factor kappaB signaling pathway","volume":"67","author":"Liu","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2026.122187_bib79","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105420","article-title":"The role of short-chain fatty acids in intestinal barrier function, inflammation, oxidative stress, and colonic carcinogenesis","volume":"165","author":"Liu","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.jep.2026.122187_bib80","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.155329","article-title":"Study on the mechanism of modified Gegen Qinlian decoction in regulating the intestinal flora-bile acid-TGR5 axis for the treatment of type 2 diabetes mellitus based on macro genome sequencing and targeted metabonomics integration","volume":"132","author":"Liu","year":"2024","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib81","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/s41398-025-03743-3","article-title":"Alterations in short-chain fatty acid-associated gut microbiota and tight junction integrity in adolescent major depressive disorder","volume":"16","author":"Liu","year":"2025","journal-title":"Transl. Psychiatry"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib82","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s10020-025-01270-x","article-title":"ITIH4 alleviates OVA-induced asthma by regulating lung-gut microbiota","volume":"31","author":"Liu","year":"2025","journal-title":"Mol Med"},{"issue":"10","key":"10.1016\/j.jep.2026.122187_bib83","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nrmicro3344","article-title":"The gut microbiota, bacterial metabolites and colorectal cancer","volume":"12","author":"Louis","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib84","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2009.01514.x","article-title":"Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine","volume":"294","author":"Louis","year":"2009","journal-title":"FEMS Microbiol. Lett."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib85","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/1462-2920.13589","article-title":"Formation of propionate and butyrate by the human colonic microbiota","volume":"19","author":"Louis","year":"2017","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.jep.2026.122187_bib86","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116423","article-title":"Jingfang Granule alleviates bleomycin-induced acute lung injury via CD200-CD200R immunoregulatory pathway","volume":"311","author":"Lv","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib87","article-title":"Macrophages in sepsis-induced acute lung injury: exosomal modulation and therapeutic potential","volume":"15","author":"Lv","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jep.2026.122187_bib88","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117429","article-title":"Efficacy and safety of tanreqing injection for cough caused by acute trachea-bronchitis disease: a systematic review and meta-analysis of randomized controlled trials","volume":"321","author":"Ma","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib89","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155645","article-title":"Integrated pharmacokinetic properties and tissue distribution of multiple active constituents in Qing-Yi Recipe: a comparison between granules and decoction","volume":"129","author":"Ma","year":"2024","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib90","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1165\/rcmb.2020-0196TR","article-title":"The gut-lung axis in systemic inflammation. Role of mesenteric lymph as a conduit","volume":"64","author":"Ma","year":"2021","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"8","key":"10.1016\/j.jep.2026.122187_bib91","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/s41577-024-01014-8","article-title":"Short-chain fatty acids: linking diet, the microbiome and immunity","volume":"24","author":"Mann","year":"2024","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib92","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1017\/S0029665120006916","article-title":"SCFA: mechanisms and functional importance in the gut","volume":"80","author":"Martin-Gallausiaux","year":"2021","journal-title":"Proc. Nutr. Soc."},{"issue":"4","key":"10.1016\/j.jep.2026.122187_bib93","doi-asserted-by":"crossref","DOI":"10.3390\/antiox12040880","article-title":"Dietary phenolic compounds: their health benefits and Association with the Gut Microbiota","volume":"12","author":"Matsumura","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.jep.2026.122187_bib94","article-title":"In vitro colonic fermentation of dietary fibers: fermentation rate, short-chain fatty acid production and changes in microbiota","author":"Miaomiao","year":"2019","journal-title":"Trends Food Sci. Technol."},{"issue":"3","key":"10.1016\/j.jep.2026.122187_bib95","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.168443","article-title":"Abnormalities in microbiota\/butyrate\/FFAR3 signaling in aging gut impair brain function","volume":"9","author":"Mishra","year":"2024","journal-title":"JCI Insight"},{"issue":"22","key":"10.1016\/j.jep.2026.122187_bib96","doi-asserted-by":"crossref","first-page":"5078","DOI":"10.1111\/bph.15226","article-title":"Protective effects of Delta(9) -tetrahydrocannabinol against enterotoxin-induced acute respiratory distress syndrome are mediated by modulation of microbiota","volume":"177","author":"Mohammed","year":"2020","journal-title":"Br. J. Pharmacol."},{"issue":"22","key":"10.1016\/j.jep.2026.122187_bib97","doi-asserted-by":"crossref","first-page":"5078","DOI":"10.1111\/bph.15226","article-title":"Protective effects of \u0394(9) -tetrahydrocannabinol against enterotoxin-induced acute respiratory distress syndrome are mediated by modulation of microbiota","volume":"177","author":"Mohammed","year":"2020","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.jep.2026.122187_bib98","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/19490976.2015.1134082","article-title":"Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism","volume":"7","author":"Morrison","year":"2016","journal-title":"Gut Microbes"},{"issue":"11","key":"10.1016\/j.jep.2026.122187_bib99","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1097\/01.MIB.0000186408.07769.78","article-title":"Infliximab treatment does not induce organ-specific or nonorgan-specific autoantibodies other than antinuclear and anti-double-stranded DNA autoantibodies in Crohn's disease","volume":"11","author":"Nancey","year":"2005","journal-title":"Inflamm. Bowel Dis."},{"issue":"22","key":"10.1016\/j.jep.2026.122187_bib100","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.191538","article-title":"The septin cytoskeleton is a regulator of intestinal epithelial barrier integrity and mucosal inflammation","volume":"10","author":"Naydenov","year":"2025","journal-title":"JCI Insight"},{"issue":"3","key":"10.1016\/j.jep.2026.122187_bib101","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.230014","article-title":"Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections","volume":"13","author":"Ney","year":"2023","journal-title":"Open Biol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib102","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1465-9921-11-33","article-title":"Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice","volume":"11","author":"Ni","year":"2010","journal-title":"Respir. Res."},{"key":"10.1016\/j.jep.2026.122187_bib103","doi-asserted-by":"crossref","first-page":"532","DOI":"10.3389\/fendo.2020.00532","article-title":"The membrane transporter OAT7 (SLC22A9) is not a susceptibility factor for osteoporosis in Europeans","volume":"11","author":"Nies","year":"2020","journal-title":"Front. Endocrinol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib104","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/s42255-024-01191-9","article-title":"Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression","volume":"7","author":"Nshanian","year":"2025","journal-title":"Nat. Metab."},{"issue":"10","key":"10.1016\/j.jep.2026.122187_bib105","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.tcb.2020.08.004","article-title":"Tight junction structure and function revisited","volume":"30","author":"Otani","year":"2020","journal-title":"Trends Cell Biol."},{"issue":"24","key":"10.1016\/j.jep.2026.122187_bib106","doi-asserted-by":"crossref","first-page":"12621","DOI":"10.1039\/D1FO02407H","article-title":"Baicalin inhibits APEC-induced lung injury by regulating gut microbiota and SCFA production","volume":"12","author":"Peng","year":"2021","journal-title":"Food Funct."},{"issue":"6","key":"10.1016\/j.jep.2026.122187_bib107","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1038\/ismej.2014.14","article-title":"Phylogenetic distribution of three pathways for propionate production within the human gut microbiota","volume":"8","author":"Reichardt","year":"2014","journal-title":"ISME J."},{"issue":"9","key":"10.1016\/j.jep.2026.122187_bib108","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1080\/10408398.2022.2124231","article-title":"Short-chain fatty acid: an updated review on signaling, metabolism, and therapeutic effects","volume":"64","author":"Rekha","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib109","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2440125","article-title":"Role of gut microbes in acute lung injury\/acute respiratory distress syndrome","volume":"16","author":"Ren","year":"2024","journal-title":"Gut Microbes"},{"issue":"29","key":"10.1016\/j.jep.2026.122187_bib110","doi-asserted-by":"crossref","first-page":"22082","DOI":"10.1074\/jbc.M110.117713","article-title":"Dissecting the in vivo metabolic potential of two human gut acetogens","volume":"285","author":"Rey","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jep.2026.122187_bib111","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2025.123913","article-title":"GPR41 and GPR43 modulate rodent pancreatic alpha-cell function and growth","volume":"379","author":"Sanchez-Roncero","year":"2025","journal-title":"Life Sci."},{"issue":"4","key":"10.1016\/j.jep.2026.122187_bib112","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1002\/jsfa.10024","article-title":"Propolis: types, composition, biological activities, and veterinary product patent prospecting","volume":"100","author":"Santos","year":"2020","journal-title":"J. Sci. Food Agric."},{"key":"10.1016\/j.jep.2026.122187_bib113","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2024.1367864","article-title":"Fiber rich food suppressed airway inflammation, GATA3 + Th2 cells, and FcepsilonRIalpha+ eosinophils in asthma","volume":"11","author":"Schenzel","year":"2024","journal-title":"Front. Nutr."},{"issue":"12","key":"10.1016\/j.jep.2026.122187_bib114","doi-asserted-by":"crossref","first-page":"4340","DOI":"10.1128\/JB.00137-06","article-title":"Whole-genome transcription profiling reveals genes up-regulated by growth on fucose in the human gut bacterium \"Roseburia inulinivorans\"","volume":"188","author":"Scott","year":"2006","journal-title":"J. Bacteriol."},{"issue":"23","key":"10.1016\/j.jep.2026.122187_bib115","doi-asserted-by":"crossref","first-page":"10401","DOI":"10.1039\/D3FO04051H","article-title":"Akkermansia muciniphila attenuated lipopolysaccharide-induced acute lung injury by modulating the gut microbiota and SCFAs in mice","volume":"14","author":"Shen","year":"2023","journal-title":"Food Funct."},{"key":"10.1016\/j.jep.2026.122187_bib116","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ijbiomac.2020.04.211","article-title":"Regulating the balance of Th17\/Treg cells in gut-lung axis contributed to the therapeutic effect of Houttuynia cordata polysaccharides on H1N1-induced acute lung injury","volume":"158","author":"Shi","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"issue":"12","key":"10.1016\/j.jep.2026.122187_bib117","first-page":"5244","article-title":"Sodium propionate and sodium butyrate effects on histone deacetylase (HDAC) activity, histone acetylation, and inflammatory gene expression in bovine mammary epithelial cells","volume":"96","author":"Silva","year":"2018","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.jep.2026.122187_bib118","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.111526","article-title":"Efficacy of Brazilian green propolis (EPP-AF(R)) as an adjunct treatment for hospitalized COVID-19 patients: a randomized, controlled clinical trial","volume":"138","author":"Silveira","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.jep.2026.122187_bib119","article-title":"Butyrate producers, \"The Sentinel of Gut\": their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics","volume":"13","author":"Singh","year":"2022","journal-title":"Front. Microbiol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib120","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/j.2040-4603.2018.tb00009.x","article-title":"Short-Chain fatty acid transporters: role in colonic homeostasis","volume":"8","author":"Sivaprakasam","year":"2017","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.jep.2026.122187_bib121","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.112907","article-title":"Huperzine a ameliorates sepsis-induced acute lung injury by suppressing inflammation and oxidative stress via alpha7 nicotinic acetylcholine receptor","volume":"141","author":"Su","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib122","article-title":"Function of uric acid transporters and their inhibitors in hyperuricaemia","volume":"12","author":"Sun","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib123","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00535-016-1242-9","article-title":"Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases","volume":"52","author":"Sun","year":"2017","journal-title":"J. Gastroenterol."},{"key":"10.1016\/j.jep.2026.122187_bib124","article-title":"The gut-lung axis in severe pneumonia-related lung injury: mechanisms and therapeutic strategies","volume":"16","author":"Sun","year":"2025","journal-title":"Front. Immunol."},{"issue":"Pt A","key":"10.1016\/j.jep.2026.122187_bib125","article-title":"Jingfang Granules ( ) alleviates bleomycin-induced acute lung injury through regulating PI3K\/Akt\/mTOR signaling pathway","volume":"318","author":"Sun","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib126","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117789","article-title":"Anti-inflammatory, analgesic, antitussive and antipyretic activities of polyphenol-enriched fraction from Nymphaea candida","volume":"324","author":"Sun","year":"2024","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib127","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.jaci.2022.11.007","article-title":"Dietary fiber and SCFAs in the regulation of mucosal immunity","volume":"151","author":"Tan","year":"2023","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.jep.2026.122187_bib128","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1351295","article-title":"Unlocking the potential of Rosa roxburghii Tratt polyphenol: a novel approach to treating acute lung injury from a perspective of the lung-gut axis","volume":"15","author":"Tang","year":"2024","journal-title":"Front. Microbiol."},{"issue":"12","key":"10.1016\/j.jep.2026.122187_bib129","doi-asserted-by":"crossref","first-page":"4258","DOI":"10.1002\/fsn3.3019","article-title":"Analysis of protective effects of Rosa Roxburghii Tratt fruit polyphenols on lipopolysaccharide-induced acute lung injury through network pharmacology and metabolomics","volume":"10","author":"Tang","year":"2022","journal-title":"Food Sci. Nutr."},{"issue":"6","key":"10.1016\/j.jep.2026.122187_bib130","doi-asserted-by":"crossref","first-page":"3079","DOI":"10.1021\/acs.jafc.2c04344","article-title":"Integrated proteomics and metabolomics analysis to explore the amelioration mechanisms of Rosa roxburghii Tratt fruit polyphenols on lipopolysaccharide-induced acute lung injury mice","volume":"71","author":"Tang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2026.122187_bib131","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/6183551","article-title":"Huoxiang zhengqi oral liquid attenuates LPS-induced acute lung injury by modulating short-chain fatty acid levels and TLR4\/NF-kappaB p65 pathway","volume":"2023","author":"Tang","year":"2023","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.jep.2026.122187_bib132","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.72171","article-title":"Short-chain fatty acids activate acetyltransferase p300","volume":"10","author":"Thomas","year":"2021","journal-title":"eLife"},{"key":"10.1016\/j.jep.2026.122187_bib133","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113663","article-title":"Ambient ozone exposure induces ROS related-mitophagy and pyroptosis via NLRP3 inflammasome activation in rat lung cells","volume":"240","author":"Tian","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"15","key":"10.1016\/j.jep.2026.122187_bib134","doi-asserted-by":"crossref","DOI":"10.3390\/cells12151981","article-title":"The role of cytokines in neutrophil development, tissue homing, function and plasticity in health and disease","volume":"12","author":"Tsioumpekou","year":"2023","journal-title":"Cells"},{"issue":"10","key":"10.1016\/j.jep.2026.122187_bib135","doi-asserted-by":"crossref","DOI":"10.1111\/obr.13498","article-title":"Butyrate to combat obesity and obesity-associated metabolic disorders: current status and future implications for therapeutic use","volume":"23","author":"van Deuren","year":"2022","journal-title":"Obes. Rev."},{"key":"10.1016\/j.jep.2026.122187_bib136","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6646923","article-title":"Oxidative imbalance as a crucial factor in inflammatory lung diseases: could antioxidant treatment constitute a new therapeutic strategy?","volume":"2021","author":"Victoni","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib137","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/cbf.1533","article-title":"Effects of short chain fatty acids on effector mechanisms of neutrophils","volume":"27","author":"Vinolo","year":"2009","journal-title":"Cell Biochem. Funct."},{"issue":"9","key":"10.1016\/j.jep.2026.122187_bib138","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.jnutbio.2010.07.009","article-title":"Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils","volume":"22","author":"Vinolo","year":"2011","journal-title":"J. Nutr. Biochem."},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib139","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00889-14","article-title":"Revealing the bacterial butyrate synthesis pathways by analyzing (meta)genomic data","volume":"5","author":"Vital","year":"2014","journal-title":"mBio"},{"key":"10.1016\/j.jep.2026.122187_bib140","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112445","article-title":"Chimonanthus nitens oliv. essential oil mitigates lipopolysaccharide-induced acute lung injury in rats","volume":"156","author":"Wan","year":"2021","journal-title":"Food Chem. Toxicol."},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib141","first-page":"183","article-title":"Efficacy and safety of artificial bear bile powder in the treatment of acute Pharyngitis(Syndrome of Gan-Wei stagnant heat):a multicenter randomized controlled trial","volume":"45","author":"Wang","year":"2025","journal-title":"Chin. J. Integr. Tradit. West. Med."},{"issue":"40","key":"10.1016\/j.jep.2026.122187_bib142","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202203432","article-title":"Fluorous-tagged peptide nanoparticles ameliorate acute lung injury via lysosomal stabilization and inflammation inhibition in pulmonary macrophages","volume":"18","author":"Wang","year":"2022","journal-title":"Small"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib143","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.chom.2023.11.005","article-title":"Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis","volume":"32","author":"Wang","year":"2024","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.jep.2026.122187_bib144","article-title":"Targeting gut microbiota for diabetic nephropathy treatment: probiotics, dietary interventions, and fecal microbiota transplantation","volume":"16","author":"Wang","year":"2025","journal-title":"Front. Endocrinol."},{"issue":"Pt 1","key":"10.1016\/j.jep.2026.122187_bib145","article-title":"Glycyrrhizic acid and patchouli alcohol in Huoxiang Zhengqi attenuate intestinal inflammation and barrier injury via regulating endogenous corticosterone metabolism mediated by 11beta-HSD1","volume":"338","author":"Wang","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"40","key":"10.1016\/j.jep.2026.122187_bib146","doi-asserted-by":"crossref","first-page":"14638","DOI":"10.1021\/acs.jafc.3c04417","article-title":"Butyrate protects against gamma-d-Glutamyl-meso-diaminopimelic acid-induced inflammatory response and tight junction disruption through histone deacetylase 3 inhibition in bovine mammary epithelial cells","volume":"71","author":"Wang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2026.122187_bib147","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116538","article-title":"Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro","volume":"313","author":"Wang","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib148","article-title":"Intestinal microbiota - an unmissable bridge to severe acute pancreatitis-associated acute lung injury","volume":"13","author":"Wang","year":"2022","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.jep.2026.122187_bib149","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.03664-22","article-title":"Mechanisms of qingyi decoction in severe acute pancreatitis-associated acute lung injury via Gut Microbiota: targeting the short-chain fatty acids-mediated AMPK\/NF-kappaB\/NLRP3 pathway","volume":"11","author":"Wang","year":"2023","journal-title":"Microbiol. Spectr."},{"issue":"49","key":"10.1016\/j.jep.2026.122187_bib150","article-title":"The efficacy and safety of modified Gegenqinlian Fomular for advanced colorectal cancer (damp heat accumulation type): a multicenter randomized controlled trial","volume":"100","author":"Wang","year":"2021","journal-title":"Medicine (Baltim.)"},{"key":"10.1016\/j.jep.2026.122187_bib151","article-title":"Pharmacological effects of baicalin in lung diseases","volume":"14","author":"Wang","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"8","key":"10.1016\/j.jep.2026.122187_bib152","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1089\/jicm.2022.0672","article-title":"Huo Xiang Zheng Qi oral liquid combined with 5-HT3 receptor antagonists and dexamethasone can prevent chemotherapy-induced nausea and vomiting for patients receiving multiday cisplatin-based regimen: a multicenter trial","volume":"29","author":"Wei","year":"2023","journal-title":"J Integr Complement Med"},{"key":"10.1016\/j.jep.2026.122187_bib153","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.176219","article-title":"Sodium butyrate ameliorates sepsis-associated lung injury by enhancing gut and lung barrier function in combination with modulation of CD4(+)Foxp3(+) regulatory T cells","volume":"963","author":"Wei","year":"2024","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib154","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.741934","article-title":"Stigmasterol restores the balance of Treg\/Th17 cells by activating the Butyrate-PPARgamma axis in colitis","volume":"12","author":"Wen","year":"2021","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.jep.2026.122187_bib155","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1038\/s41423-021-00647-2","article-title":"The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes","volume":"18","author":"Wiechers","year":"2021","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.jep.2026.122187_bib156","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155490","article-title":"Strictosamide alleviates acute lung injury via regulating T helper 17 cells, regulatory T cells, and gut microbiota","volume":"128","author":"Wu","year":"2024","journal-title":"Phytomedicine"},{"issue":"7","key":"10.1016\/j.jep.2026.122187_bib157","first-page":"1915","article-title":"[Therapeutic effect and mechanism of Jingfang Granules on acute lung injury based on intestinal flora and fecal metabolomics]","volume":"49","author":"Xiao","year":"2024","journal-title":"Zhongguo Zhongyao Zazhi"},{"key":"10.1016\/j.jep.2026.122187_bib158","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2023.101737","article-title":"A major mechanism for immunomodulation: dietary fibres and acid metabolites","volume":"66","author":"Xie","year":"2023","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.jep.2026.122187_bib159","article-title":"Therapeutic potential of short-chain fatty acids for acute lung injury: a systematic review and meta-analysis of preclinical animal studies","volume":"11","author":"Xie","year":"2024","journal-title":"Front. Nutr."},{"key":"10.1016\/j.jep.2026.122187_bib160","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.12659\/MSM.911444","article-title":"Intraperitoneal injection of acetate protects mice against lipopolysaccharide (LPS)-induced acute lung injury through its Anti-In fl ammatory and anti-oxidative ability","volume":"25","author":"Xu","year":"2019","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.jep.2026.122187_bib161","article-title":"Short-chain fatty acids: key antiviral mediators of gut microbiota","volume":"16","author":"Xu","year":"2025","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib162","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/s00018-024-05474-y","article-title":"Gut microbiota-derived acetic acids promoted sepsis-induced acute respiratory distress syndrome by delaying neutrophil apoptosis through FABP4","volume":"81","author":"Xuan","year":"2024","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.jep.2026.122187_bib163","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132013","article-title":"Sodium butyrate alleviates deoxynivalenol-induced porcine intestinal barrier disruption by promoting mitochondrial homeostasis via PCK2 signaling","volume":"459","author":"Xue","year":"2023","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.jep.2026.122187_bib164","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2020.153403","article-title":"Effects and safety of herbal medicines among community-dwelling residents during COVID-19 pandemic: a large prospective, randomized controlled trial (RCT)","volume":"85","author":"Yan","year":"2021","journal-title":"Phytomedicine"},{"issue":"10","key":"10.1016\/j.jep.2026.122187_bib165","first-page":"2819","article-title":"[Randomized double-blind placebo-controlled trial of jingfang granules in treatment of common cold(wind-cold syndrome)]","volume":"47","author":"Yang","year":"2022","journal-title":"Zhongguo Zhongyao Zazhi"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib166","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2363020","article-title":"Microbial metabolite butyrate modulates granzyme B in tolerogenic IL-10 producing Th1 cells to regulate intestinal inflammation","volume":"16","author":"Yang","year":"2024","journal-title":"Gut Microbes"},{"key":"10.1016\/j.jep.2026.122187_bib167","doi-asserted-by":"crossref","first-page":"7323","DOI":"10.2147\/JIR.S522638","article-title":"Ethyl acetate extract of Elsholtzia bodinieri vaniot attenuates oxidative stress in ALI mice","volume":"18","author":"Yin","year":"2025","journal-title":"J. Inflamm. Res."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib168","first-page":"413","article-title":"Sodium butyrate relieves lung ischemia-reperfusion injury by inhibiting NF-kappaB and JAK2\/STAT3 signaling pathways","volume":"25","author":"Ying","year":"2021","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib169","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/s41392-025-02263-2","article-title":"Microbiota-derived butyrate alleviates asthma via inhibiting Tfh13-mediated IgE production","volume":"10","author":"Yu","year":"2025","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"Pt B","key":"10.1016\/j.jep.2026.122187_bib170","article-title":"Gut microbiota-derived autoinducer-2 regulates lung inflammation through the gut-lung axis","volume":"124","author":"Zeng","year":"2023","journal-title":"Int. Immunopharmacol."},{"issue":"8","key":"10.1016\/j.jep.2026.122187_bib171","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpha.2025.101342","article-title":"Quantifying compatibility mechanisms in traditional Chinese medicine with interpretable graph neural networks","volume":"15","author":"Zeng","year":"2025","journal-title":"J. Pharm. Anal."},{"issue":"7","key":"10.1016\/j.jep.2026.122187_bib172","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1007\/s00268-010-0493-5","article-title":"Histone deacetylase inhibitors attenuate acute lung injury during cecal ligation and puncture-induced polymicrobial sepsis","volume":"34","author":"Zhang","year":"2010","journal-title":"World J. Surg."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib173","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2025.2519706","article-title":"Gut microbial metabolite butyrate suppresses hepatocellular carcinoma growth via CXCL11-dependent enhancement of natural killer cell infiltration","volume":"17","author":"Zhang","year":"2025","journal-title":"Gut Microbes"},{"key":"10.1016\/j.jep.2026.122187_bib174","doi-asserted-by":"crossref","DOI":"10.1177\/15347354241293790","article-title":"Evaluation of the efficacy, safety, and clinical outcomes of ginsenosides as adjuvant therapy in hepatocellular carcinoma: a meta-analysis and systematic review","volume":"23","author":"Zhang","year":"2024","journal-title":"Integr. Cancer Ther."},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib175","doi-asserted-by":"crossref","first-page":"189","DOI":"10.14715\/cmb\/2022.68.2.27","article-title":"Effects of Gegen Qinlian Decoction combined with Chinese herbal hot package on the expression of PCT, CRP and IL-6 in patients with acute gastroenteritis","volume":"68","author":"Zhang","year":"2022","journal-title":"Cell. Mol. Biol. (Noisy-Le-Grand)"},{"key":"10.1016\/j.jep.2026.122187_bib176","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106749","article-title":"Baricitinib, a drug with potential effect to prevent SARS-COV-2 from entering target cells and control cytokine storm induced by COVID-19","volume":"86","author":"Zhang","year":"2020","journal-title":"Int. Immunopharmacol."},{"issue":"8","key":"10.1016\/j.jep.2026.122187_bib177","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1080\/10408398.2023.2293254","article-title":"Advances in dietary polysaccharides as hypoglycemic agents: mechanisms, structural characteristics, and innovative applications","volume":"65","author":"Zhang","year":"2025","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"6","key":"10.1016\/j.jep.2026.122187_bib178","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1165\/rcmb.2021-0515OC","article-title":"Intestinal microbiota-derived propionic acid protects against zinc oxide nanoparticle-induced lung injury","volume":"67","author":"Zhang","year":"2022","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib179","doi-asserted-by":"crossref","first-page":"7600","DOI":"10.1038\/s41467-022-35347-6","article-title":"Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis","volume":"13","author":"Zhao","year":"2022","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.jep.2026.122187_bib180","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1038\/mi.2017.118","article-title":"GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3","volume":"11","author":"Zhao","year":"2018","journal-title":"Mucosal Immunol."},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib181","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.70006","article-title":"Time-restricted feeding mitigates Alzheimer's disease-associated cognitive impairments via a B. Pseudolongum-propionic acid-FFAR3 axis","volume":"4","author":"Zhao","year":"2025","journal-title":"iMeta"},{"issue":"5","key":"10.1016\/j.jep.2026.122187_bib182","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.01987-23","article-title":"Butyrate protects against MRSA pneumonia via regulating gut-lung microbiota and alveolar macrophage M2 polarization","volume":"14","author":"Zhao","year":"2023","journal-title":"mBio"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib183","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13045-024-01529-6","article-title":"FFAR2 expressing myeloid-derived suppressor cells drive cancer immunoevasion","volume":"17","author":"Zhao","year":"2024","journal-title":"J. Hematol. Oncol."},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib184","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s40168-024-01772-6","article-title":"Intact lung tissue and bronchoalveolar lavage fluid are both suitable for the evaluation of murine lung microbiome in acute lung injury","volume":"12","author":"Zheng","year":"2024","journal-title":"Microbiome"},{"issue":"1","key":"10.1016\/j.jep.2026.122187_bib185","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202200597","article-title":"Butyrate attenuates hepatic steatosis induced by a high-fat and fiber-deficient diet via the hepatic GPR41\/43-CaMKII\/HDAC1-CREB pathway","volume":"67","author":"Zheng","year":"2023","journal-title":"Mol. Nutr. Food Res."},{"issue":"18","key":"10.1016\/j.jep.2026.122187_bib186","doi-asserted-by":"crossref","first-page":"5392","DOI":"10.1021\/acs.jafc.0c08197","article-title":"Isolated pea resistant starch substrates with different structural features modulate the production of short-chain fatty acids and metabolism of microbiota in anaerobic fermentation in vitro","volume":"69","author":"Zhou","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jep.2026.122187_bib187","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2024.113607","article-title":"Gegen Qinlian Decoction improves H1N1-induced viral pneumonia by modulating the \"gut microbiota-metabolomics-immune\/inflammation\" axis","volume":"144","author":"Zhou","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jep.2026.122187_bib188","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2025.124280","article-title":"Acetate produced by the interaction between Houttuynia pectin and Phocaeicola vulgatus alleviated H1N1-induced acute lung injury in mice through the GPR43\/JAK2\/STAT3 pathway","volume":"369","author":"Zhu","year":"2025","journal-title":"Carbohydr. Polym."},{"issue":"3","key":"10.1016\/j.jep.2026.122187_bib189","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1002\/jsfa.70269","article-title":"Synergistic regulation of crude Sphallerocarpus gracilis polysaccharides and probiotics on intestinal flora and its immune-related metabolites in rats","volume":"106","author":"Zhu","year":"2026","journal-title":"J. Sci. Food Agric."},{"issue":"2","key":"10.1016\/j.jep.2026.122187_bib190","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2249143","article-title":"Microbial metabolite butyrate promotes anti-PD-1 antitumor efficacy by modulating T cell receptor signaling of cytotoxic CD8 T cell","volume":"15","author":"Zhu","year":"2023","journal-title":"Gut Microbes"}],"container-title":["Journal of Ethnopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412601041X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037887412601041X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:37:04Z","timestamp":1790775424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S037887412601041X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":190,"alternative-id":["S037887412601041X"],"URL":"https:\/\/doi.org\/10.1016\/j.jep.2026.122187","relation":{},"ISSN":["0378-8741"],"issn-type":[{"value":"0378-8741","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Short-chain fatty acid metabolism in acute lung injury and intervention strategies from traditional Chinese medicine","name":"articletitle","label":"Article Title"},{"value":"Journal of Ethnopharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jep.2026.122187","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"122187"}}