{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T04:00:00Z","timestamp":1792900800646,"version":"4.5.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010877","name":"Science, Technology and Innovation Commission of Shenzhen Municipality","doi-asserted-by":"publisher","award":["KQTD20190929172630447"],"award-info":[{"award-number":["KQTD20190929172630447"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52170156"],"award-info":[{"award-number":["52170156"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52250056"],"award-info":[{"award-number":["52250056"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52293442"],"award-info":[{"award-number":["52293442"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Environmental Sciences"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.jes.2023.04.012","type":"journal-article","created":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T00:27:15Z","timestamp":1682209635000},"page":"227-235","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["A global perspective on microbial risk factors in effluents of wastewater treatment plants"],"prefix":"10.1016","volume":"138","author":[{"given":"Kejing","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6689-4068","authenticated-orcid":false,"given":"Jinsong","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yechen","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aijie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jes.2023.04.012_bib0001","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/2049-632X.12125","article-title":"Acinetobacter baumannii: evolution of a global pathogen","volume":"71","author":"Antunes","year":"2014","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.jes.2023.04.012_bib0002","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/etc.2784","article-title":"Urban wastewater effluent increases antibiotic resistance gene concentrations in a receiving northern European river","volume":"34","author":"Berglund","year":"2015","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.jes.2023.04.012_bib0003","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.tim.2020.05.011","article-title":"The role of integrative and conjugative elements in antibiotic resistance evolution","volume":"29","author":"Botelho","year":"2021","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.jes.2023.04.012_bib0004","doi-asserted-by":"crossref","first-page":"e893","DOI":"10.1016\/S2542-5196(21)00280-1","article-title":"Global antibiotic consumption and usage in humans, 2000\u201318: a spatial modelling study","volume":"5","author":"Browne","year":"2021","journal-title":"Lancet Planet. Health"},{"key":"10.1016\/j.jes.2023.04.012_bib0005","doi-asserted-by":"crossref","first-page":"D325","DOI":"10.1093\/nar\/gki008","article-title":"VFDB: a reference database for bacterial virulence factors","volume":"33","author":"Chen","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jes.2023.04.012_bib0006","doi-asserted-by":"crossref","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","article-title":"fastp: an ultra-fast all-in-one FASTQ preprocessor","volume":"34","author":"Chen","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jes.2023.04.012_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135811","article-title":"Bacterial removal performance and community changes during advanced treatment process: A case study at a full-scale water reclamation plant","volume":"705","author":"Cui","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jes.2023.04.012_bib0008","first-page":"33","article-title":"Antimicrobial resistance in ESKAPE pathogens","author":"De Oliveira","year":"2020","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.jes.2023.04.012_bib0009","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1038\/ismej.2016.90","article-title":"Phages rarely encode antibiotic resistance genes: a cautionary tale for virome analyses","volume":"11","author":"Enault","year":"2017","journal-title":"ISME J"},{"key":"10.1016\/j.jes.2023.04.012_bib0010","doi-asserted-by":"crossref","DOI":"10.1093\/gigascience\/giz066","article-title":"PPR-Meta: a tool for identifying phages and plasmids from metagenomic fragments using deep learning","volume":"8","author":"Fang","year":"2019","journal-title":"GigaScience"},{"key":"10.1016\/j.jes.2023.04.012_bib0011","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1007\/s10142-022-00903-2","article-title":"Breaking the ICE: an easy workflow for identifying and analyzing integrative and conjugative elements in bacterial genomes","volume":"22","author":"Gon\u00e7alves","year":"2022","journal-title":"Funct. Integr. Genomics"},{"key":"10.1016\/j.jes.2023.04.012_bib0012","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.watres.2019.05.034","article-title":"Simultaneous removal of antibiotics and antibiotic resistance genes from pharmaceutical wastewater using the combinations of up-flow anaerobic sludge bed, anoxic-oxic tank, and advanced oxidation technologies","volume":"159","author":"Hou","year":"2019","journal-title":"Water Res"},{"key":"10.1016\/j.jes.2023.04.012_bib0013","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/ncomms3151","article-title":"Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota","volume":"4","author":"Hu","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jes.2023.04.012_bib0014","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1078\/1438-4221-00173","article-title":"The role of motility as a virulence factor in bacteria","volume":"291","author":"Josenhans","year":"2002","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.jes.2023.04.012_bib0015","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s11270-021-05154-8","article-title":"Wastewater treatment and reuse: a review of its applications and health implications","volume":"232","author":"Kesari","year":"2021","journal-title":"Water, Air, Soil Pollut"},{"key":"10.1016\/j.jes.2023.04.012_bib0016","doi-asserted-by":"crossref","first-page":"174","DOI":"10.3389\/fmicb.2016.00174","article-title":"Breaking the spell: combating multidrug resistant 'superbugs'","volume":"7","author":"Khan","year":"2016","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jes.2023.04.012_bib0017","series-title":"Pet-To-Man Travelling Staphylococci","first-page":"11","article-title":"Chapter 2 - Staphylococcal ecology and epidemiology","author":"Kosecka-Strojek","year":"2018"},{"key":"10.1016\/j.jes.2023.04.012_bib0018","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.envint.2018.03.019","article-title":"Phage particles harboring antibiotic resistance genes in fresh-cut vegetables and agricultural soil","volume":"115","author":"Larra\u00f1aga","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.jes.2023.04.012_bib0019","first-page":"1650","article-title":"The occurrence and diversity of antibiotic resistance and virulence factor genes in wastewater from four North American treatment plants","volume":"8","author":"Le","year":"2022","journal-title":"Environ. Sci.: Water Res. Technol."},{"key":"10.1016\/j.jes.2023.04.012_bib0020","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ymeth.2016.02.020","article-title":"MEGAHIT v1.0: A fast and scalable metagenome assembler driven by advanced methodologies and community practices","volume":"102","author":"Li","year":"2016","journal-title":"Methods"},{"key":"10.1016\/j.jes.2023.04.012_bib0021","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.watres.2017.01.010","article-title":"Removal of antibiotic resistance genes from wastewater treatment plant effluent by coagulation","volume":"111","author":"Li","year":"2017","journal-title":"Water Res"},{"key":"10.1016\/j.jes.2023.04.012_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111885","article-title":"Removal of antibiotic resistance genes from swine wastewater by membrane filtration treatment","volume":"210","author":"Liang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jes.2023.04.012_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2023.119822","article-title":"A global perspective on compositions, risks, and ecological genesis of antibiotic resistance genes in biofilters of drinking water treatment plants","volume":"233","author":"Liang","year":"2023","journal-title":"Water Res."},{"key":"10.1016\/j.jes.2023.04.012_bib0024","article-title":"Identification and quantification of bacterial genomes carrying antibiotic resistance genes and virulence factor genes for aquatic microbiological risk assessment","volume":"168","author":"Liang","year":"2019","journal-title":"Water Res."},{"key":"10.1016\/j.jes.2023.04.012_bib0025","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.1038\/s41596-022-00738-y","article-title":"Metagenome analysis using the Kraken software suite","volume":"17","author":"Lu","year":"2022","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jes.2023.04.012_bib0026","first-page":"12","article-title":"Evidence of horizontal gene transfer of 50S ribosomal genes rplB, rplD, and rplY in Neisseria gonorrhoeae","author":"Manoharan-Basil","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.jes.2023.04.012_bib0027","doi-asserted-by":"crossref","first-page":"11800","DOI":"10.1038\/s41598-021-91280-6","article-title":"Antibiogram profile and virulence signatures of Pseudomonas aeruginosa isolates recovered from selected agrestic hospital effluents","volume":"11","author":"Mapipa","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jes.2023.04.012_bib0028","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgph.0001305","article-title":"Global trends in antimicrobial use in food-producing animals: 2020 to 2030","volume":"3","author":"Mulchandani","year":"2023","journal-title":"PLOS Glob. Public Health"},{"key":"10.1016\/j.jes.2023.04.012_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146964","article-title":"Monitoring antibiotic resistance genes in wastewater treatment: Current strategies and future challenges","volume":"783","author":"Nguyen","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jes.2023.04.012_bib0030","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1146\/annurev.biochem.78.082907.145923","article-title":"Multidrug resistance in bacteria","volume":"78","author":"Nikaido","year":"2009","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.jes.2023.04.012_bib0031","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00821-19","article-title":"Coexistence of antibiotic resistance genes and virulence factors deciphered by large-scale complete genome analysis","author":"Pan","year":"2020","journal-title":"mSystems,"},{"key":"10.1016\/j.jes.2023.04.012_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154154","article-title":"The prevalence and removal of antibiotic resistance genes in full-scale wastewater treatment plants: Bacterial host, influencing factors and correlation with nitrogen metabolic pathway","volume":"827","author":"Ping","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jes.2023.04.012_bib0033","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.ARBA-0026-2017","article-title":"Antimicrobial resistance in Escherichia coli","volume":"6","author":"Poirel","year":"2018","journal-title":"Microbiol. Spectrum"},{"key":"10.1016\/j.jes.2023.04.012_bib0034","doi-asserted-by":"crossref","first-page":"e77015","DOI":"10.7554\/eLife.77015","article-title":"Ecology, more than antibiotics consumption, is the major predictor for the global distribution of aminoglycoside-modifying enzymes","volume":"12","author":"Pradier","year":"2023","journal-title":"eLife"},{"key":"10.1016\/j.jes.2023.04.012_bib0035","doi-asserted-by":"crossref","first-page":"7445","DOI":"10.1021\/es060413l","article-title":"Antibiotic resistance genes as emerging contaminants: studies in northern Colorado","volume":"40","author":"Pruden","year":"2006","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jes.2023.04.012_bib0036","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1186\/s13059-019-1891-0","article-title":"Improved metagenomic analysis with Kraken 2","volume":"20","author":"Wood","year":"2019","journal-title":"Genome Biol."},{"key":"10.1016\/j.jes.2023.04.012_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.152190","article-title":"Rapid absolute quantification of pathogens and ARGs by nanopore sequencing","volume":"809","author":"Yang","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jes.2023.04.012_bib0038","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1093\/bioinformatics\/bty053","article-title":"ARGs-OAP v2.0 with an expanded SARG database and Hidden Markov Models for enhancement characterization and quantification of antibiotic resistance genes in environmental metagenomes","volume":"34","author":"Yin","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jes.2023.04.012_bib0039","doi-asserted-by":"crossref","first-page":"4765","DOI":"10.1038\/s41467-021-25096-3","article-title":"An omics-based framework for assessing the health risk of antimicrobial resistance genes","volume":"12","author":"Zhang","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jes.2023.04.012_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122070","article-title":"Removal of antibiotic resistant bacteria and antibiotic resistance genes in wastewater effluent by UV-activated persulfate","volume":"388","author":"Zhou","year":"2020","journal-title":"J. Hazard. Mater."}],"container-title":["Journal of Environmental Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1001074223001675?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1001074223001675?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:37:14Z","timestamp":1760870234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1001074223001675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":40,"alternative-id":["S1001074223001675"],"URL":"https:\/\/doi.org\/10.1016\/j.jes.2023.04.012","relation":{},"ISSN":["1001-0742"],"issn-type":[{"value":"1001-0742","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A global perspective on microbial risk factors in effluents of wastewater treatment plants","name":"articletitle","label":"Article Title"},{"value":"Journal of Environmental Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jes.2023.04.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}