{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T10:59:58Z","timestamp":1789297198275,"version":"build-2803163510"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42376234"],"award-info":[{"award-number":["42376234"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013142","name":"Key Research and Development Project of Hainan Province","doi-asserted-by":"publisher","award":["ZDYF2024SHFZ085"],"award-info":[{"award-number":["ZDYF2024SHFZ085"]}],"id":[{"id":"10.13039\/501100013142","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020760","name":"Sanya Yazhou Bay Science and Technology City","doi-asserted-by":"publisher","award":["2021CXLH0009"],"award-info":[{"award-number":["2021CXLH0009"]}],"id":[{"id":"10.13039\/100020760","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Environmental Sciences"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.jes.2025.04.060","type":"journal-article","created":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:22:51Z","timestamp":1745749371000},"page":"722-731","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Characteristics of regionalized distribution of antibiotics and ARGs in Daliao River-Liaodong Bay waters and their environmental impact factors"],"prefix":"10.1016","volume":"160","author":[{"given":"Bing","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjun","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9656-6591","authenticated-orcid":false,"given":"Ziwei","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jes.2025.04.060_bib0003","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jhazmat.2014.06.010","article-title":"The role of class I integrons in the dissemination of sulfonamide resistance genes in the Pearl River and Pearl River Estuary, South China","volume":"282","author":"Chen","year":"2015","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.jes.2025.04.060_bib0004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envint.2016.03.026","article-title":"Long-term field application of sewage sludge increases the abundance of antibiotic resistance genes in soil","volume":"92","author":"Chen","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.jes.2025.04.060_bib0005","doi-asserted-by":"crossref","first-page":"111360","DOI":"10.1016\/j.marpolbul.2020.111360","article-title":"Antibiotic resistance genes (ARGs) and their associated environmental factors in the Yangtze Estuary, China","volume":"158","author":"Chen","year":"2020","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.jes.2025.04.060_bib0006","doi-asserted-by":"crossref","DOI":"10.1002\/open.202400061","article-title":"Study on the mass Spectrometry Cleavage Pattern of Quinolone Antibiotics","volume":"13","author":"Fan","year":"2024","journal-title":"ChemistryOpen"},{"issue":"3","key":"10.1016\/j.jes.2025.04.060_bib0007","first-page":"779","article-title":"Advances in research on the presence and environmental behavior of antibiotics in the marine environment","volume":"42","author":"Gao","year":"2023","journal-title":"Environ. Chem."},{"issue":"5","key":"10.1016\/j.jes.2025.04.060_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.jece.2022.108297","article-title":"Occurrence and distribution of antibiotics and antibiotic resistance genes in water of Liaohe River Basin, China","volume":"10","author":"Gao","year":"2022","journal-title":"J. Environ. Chem. Eng."},{"key":"10.1016\/j.jes.2025.04.060_bib0009","series-title":"Master Thesis","article-title":"A LC-MS\/MS Method Developed to Detect 32 Drugs in Water Sampled from Selected Drain Outlets and Estuaries of the Bohai Sea","author":"Guan","year":"2016"},{"key":"10.1016\/j.jes.2025.04.060_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.138211","article-title":"Bioaccumulation and trophic transfer of antibiotics in aquatic and terrestrial habitats in the Yellow River Delta","volume":"323","author":"Hu","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.jes.2025.04.060_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.117022","article-title":"Concentrations, probabilistic human and ecological risks assessment attribute to antibiotics residues in river water in China: systematic review and meta-analysis","volume":"285","author":"Li","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jes.2025.04.060_bib0012","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jes.2022.07.021","article-title":"The fate of antibiotic resistance genes in the coastal lagoon with multiple functional zones","volume":"128","author":"Li","year":"2023","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.jes.2025.04.060_bib29","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.scitotenv.2017.09.328","article-title":"A duodecennial national synthesis of antibiotics in China\u2019s major rivers and seas (2005\u20132016)","volume":"615","author":"Li","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jes.2025.04.060_bib0013","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.scitotenv.2018.01.271","article-title":"Antibiotics in the aquatic environments: a review of lakes, China","volume":"627","author":"Liu","year":"2018","journal-title":"Sci. Total. Environ."},{"key":"10.1016\/j.jes.2025.04.060_bib0014","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.3390\/antibiotics11111461","article-title":"Occurrence and distribution of antibiotics in the water, sediment, and biota of freshwater and marine environments: a review","volume":"11","author":"Maghsodian","year":"2022","journal-title":"Antibiotics"},{"key":"10.1016\/j.jes.2025.04.060_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.133740","article-title":"Fate and removal of fluoroquinolone antibiotics in mesocosmic wetlands: impact on wetland performance, resistance genes and microbial communities","volume":"470","author":"Mu","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.jes.2025.04.060_bib0016","first-page":"2","article-title":"Opinions of the central committee of the communist party of china and the state council on the in-depth fight against pollution","volume":"12","author":"News","year":"2021","journal-title":"China Fisheries"},{"issue":"6","key":"10.1016\/j.jes.2025.04.060_bib0017","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.2166\/wh.2022.074","article-title":"Potential impact factors on the enhancement of antibiotic resistance in a lake environment","volume":"20","author":"Sorn","year":"2022","journal-title":"J. Water Health"},{"key":"10.1016\/j.jes.2025.04.060_bib0002","doi-asserted-by":"crossref","first-page":"112740","DOI":"10.1016\/j.marpolbul.2021.112740","article-title":"Genes associated with antibiotic tolerance and synthesis of antimicrobial compounds in a mangrove with contrasting salinities","volume":"171","author":"Sep\u00falveda-Correa","year":"2021","journal-title":"Mar. Bollut. Bull."},{"key":"10.1016\/j.jes.2025.04.060_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.soilbio.2021.108252","article-title":"Application of manure from cattle administered antibiotics has sustained multi-year impacts on soil resistome and microbial community structure","volume":"157","author":"Shawver","year":"2021","journal-title":"Soil Biol. Biochem."},{"key":"10.1016\/j.jes.2025.04.060_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2022.114490","article-title":"The reasons for the spatial and media distribution variations of ARGs in a typical semi-enclosed bay","volume":"187","author":"Shu","year":"2023","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.jes.2025.04.060_bib0020","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1021\/acs.est.3c07559","article-title":"D-ring modifications of tetracyclines determine their ability to induce resistance genes in the environment","volume":"58","author":"Tang","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jes.2025.04.060_bib0021","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1080\/1573062X.2022.2059688","article-title":"Antibiotics in shallow groundwater underlying urban informal settlements in developing countries: influence of on-site sanitation practices and risk assessment","volume":"20","author":"Twinomucunguzi","year":"2023","journal-title":"Urban Wate. J."},{"key":"10.1016\/j.jes.2025.04.060_bib0022","first-page":"240","article-title":"Migration and transformation of tetracycline antibiotics in environment","volume":"49","author":"Wang","year":"2020","journal-title":"Shandong Chem. Ind."},{"key":"10.1016\/j.jes.2025.04.060_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.158579","article-title":"Seasonal occurrence of multiple classes of antibiotics in East China rivers and their association with suspended particulate matter","volume":"853","author":"Wang","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jes.2025.04.060_bib0024","first-page":"72","article-title":"Analysis on the global use of veterinary antibiotics from 2018 to 2020","volume":"39","author":"Wang","year":"2022","journal-title":"China Anim. Health Inspect."},{"key":"10.1016\/j.jes.2025.04.060_bib0025","doi-asserted-by":"crossref","first-page":"756","DOI":"10.3724\/SP.J.1123.2012.03059","article-title":"Analysis of pollution levels of 16 antibiotics in the river water of Daliao River water system","volume":"30","author":"Yang","year":"2012","journal-title":"Chin. J. Chromatogr."},{"key":"10.1016\/j.jes.2025.04.060_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.140592","article-title":"Persistence of antibiotic resistance genes from river water to tap water in the Yangtze River Delta","volume":"742","author":"Yang","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jes.2025.04.060_bib0027","series-title":"Master Thesis","article-title":"Study on Distribution and Environmental Competition of Antibiotic-resistant Escherichia Coli in Typical Estuary Environments","author":"Zhang","year":"2018"},{"issue":"1","key":"10.1016\/j.jes.2025.04.060_bib0028","first-page":"109","article-title":"Occurrence and risk assessment of antibiotics in water of the lower reaches of typical rivers in Bohai Rim Basin, China","volume":"42","author":"Zhao","year":"2022","journal-title":"Environ. Sci."}],"container-title":["Journal of Environmental Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1001074225002451?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1001074225002451?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T15:53:19Z","timestamp":1761925999000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1001074225002451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":28,"alternative-id":["S1001074225002451"],"URL":"https:\/\/doi.org\/10.1016\/j.jes.2025.04.060","relation":{},"ISSN":["1001-0742"],"issn-type":[{"value":"1001-0742","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characteristics of regionalized distribution of antibiotics and ARGs in Daliao River-Liaodong Bay waters and their environmental impact factors","name":"articletitle","label":"Article Title"},{"value":"Journal of Environmental Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jes.2025.04.060","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}