{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T13:48:21Z","timestamp":1790084901447,"version":"4.0.1"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100018546","name":"Postdoctoral Innovation Project of Shandong Province","doi-asserted-by":"publisher","award":["SDCX-ZG-202203039"],"award-info":[{"award-number":["SDCX-ZG-202203039"]}],"id":[{"id":"10.13039\/501100018546","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018546","name":"Postdoctoral Innovation Project of Shandong Province","doi-asserted-by":"publisher","award":["22406114"],"award-info":[{"award-number":["22406114"]}],"id":[{"id":"10.13039\/501100018546","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2022QB231"],"award-info":[{"award-number":["ZR2022QB231"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019598","name":"Applied Basic Research Fund of Qingdao","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019598","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012620","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ts201712003"],"award-info":[{"award-number":["ts201712003"]}],"id":[{"id":"10.13039\/100012620","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22206109"],"award-info":[{"award-number":["22206109"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Environmental Sciences"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.jes.2025.06.004","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T21:48:06Z","timestamp":1749160086000},"page":"475-484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Molecular mechanisms of sulfadiazine biodegradation: The impact of intrinsic electric fields"],"prefix":"10.1016","volume":"161","author":[{"given":"Miaomiao","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2921-034X","authenticated-orcid":false,"given":"Ledong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6286-9262","authenticated-orcid":false,"given":"Qingzhu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jes.2025.06.004_bib0001","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0009-2614(89)85118-8","article-title":"Electronic structure calculations on workstation computers: the program system turbomole","volume":"162","author":"Ahlrichs","year":"1989","journal-title":"Chem. Phys. Lett."},{"issue":"25","key":"10.1016\/j.jes.2025.06.004_bib0002","doi-asserted-by":"crossref","first-page":"10580","DOI":"10.1021\/jp9536514","article-title":"Hybrid models for combined quantum mechanical and molecular mechanical approaches","volume":"100","author":"Bakowies","year":"1996","journal-title":"J. Phys. Chem."},{"issue":"10","key":"10.1016\/j.jes.2025.06.004_bib0003","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1002\/jcc.21287","article-title":"CHARMM: the biomolecular simulation program","volume":"30","author":"Brooks","year":"2009","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.jes.2025.06.004_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2024.121551","article-title":"Sulfonamide disinfection byproducts exhibited severe toxicity to human commensal bacteria","volume":"256","author":"Cai","year":"2024","journal-title":"Water Res."},{"issue":"19","key":"10.1016\/j.jes.2025.06.004_bib0005","doi-asserted-by":"crossref","first-page":"13772","DOI":"10.1039\/D3CP01899G","article-title":"Can an external electric field switch between ethylene formation and L-arginine hydroxylation in the ethylene forming enzyme?","volume":"25","author":"Chaturvedi","year":"2023","journal-title":"Phys. Chem. Chem. Phys."},{"key":"10.1016\/j.jes.2025.06.004_bib0006","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.aca.2020.02.038","article-title":"Polymerization retardation isothermal amplification strategy enables the sensitive and facile investigation of the flanking sequence preference of ten-eleven translocation 2 protein","volume":"1109","author":"Chen","year":"2020","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jes.2025.06.004_bib0007","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jes.2024.05.020","article-title":"An in-situ biochar-enhanced anaerobic membrane bioreactor for swine wastewater treatment under various organic loading rates","volume":"146","author":"Chen","year":"2024","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.jes.2025.06.004_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2023.129409","article-title":"New insight into the concentration-dependent removal of multiple antibiotics by Chlorella sorokiniana","volume":"385","author":"Chu","year":"2023","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.jes.2025.06.004_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118834","article-title":"Biotransformation of sulfamethoxazole by microalgae: removal efficiency, pathways, and mechanisms","volume":"221","author":"Chu","year":"2022","journal-title":"Water Res."},{"issue":"5","key":"10.1016\/j.jes.2025.06.004_bib0010","doi-asserted-by":"crossref","first-page":"2952","DOI":"10.1021\/acscatal.5b00423","article-title":"Benzyne formation in the mechanism-based inactivation of cytochrome P450 by 1-aminobenzotriazole and N-benzyl-1-aminobenzotriazole: computational insights","volume":"5","author":"Chuanprasit","year":"2015","journal-title":"ACS Catal."},{"issue":"2","key":"10.1016\/j.jes.2025.06.004_bib0011","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1021\/cr9002193","article-title":"Hydrocarbon hydroxylation by cytochrome P450 enzymes","volume":"110","author":"de Montellano","year":"2010","journal-title":"Chem. Rev."},{"issue":"31","key":"10.1016\/j.jes.2025.06.004_bib0012","doi-asserted-by":"crossref","first-page":"10187","DOI":"10.1021\/ja800009z","article-title":"Theory of 1,3-dipolar cycloadditions: distortion\/interaction and frontier molecular orbital models","volume":"130","author":"Ess","year":"2008","journal-title":"J. Am. Chem. Soc."},{"issue":"19","key":"10.1016\/j.jes.2025.06.004_bib0013","doi-asserted-by":"crossref","first-page":"8577","DOI":"10.1063\/1.470117","article-title":"A smooth particle mesh Ewald method","volume":"103","author":"Essmann","year":"1995","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.jes.2025.06.004_bib0014","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.cej.2017.09.024","article-title":"New insights into the chlorination of sulfonamide: smiles-type rearrangement, desulfation, and product toxicity","volume":"331","author":"Fu","year":"2018","journal-title":"Chem. Eng. J."},{"issue":"32","key":"10.1016\/j.jes.2025.06.004_bib0015","doi-asserted-by":"crossref","first-page":"11099","DOI":"10.1039\/C9DT03056E","article-title":"Coupled electron and proton transfer in the piperidine drug metabolism pathway by the active species of cytochromes P450","volume":"49","author":"Fu","year":"2020","journal-title":"Dalton Trans."},{"issue":"15","key":"10.1016\/j.jes.2025.06.004_bib0016","doi-asserted-by":"crossref","first-page":"8155","DOI":"10.1021\/acs.est.6b00524","article-title":"How PBDEs are transformed into dihydroxylated and dioxin metabolites catalyzed by the active center of cytochrome P450s: a DFT study","volume":"50","author":"Fu","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jes.2025.06.004_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.124303","article-title":"Enhanced removal of sulfadiazine by sulfidated ZVI activated persulfate process: performance, mechanisms and degradation pathways","volume":"388","author":"Guo","year":"2020","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.jes.2025.06.004_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2024.118309","article-title":"Experimental data and modeling of sulfadiazine adsorption onto raw and modified clays from Tunisia","volume":"248","author":"Hamdi","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.jes.2025.06.004_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105551","article-title":"Distribution, combined pollution and risk assessment of antibiotics in typical marine aquaculture farms surrounding the Yellow Sea, North China","volume":"138","author":"Han","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.jes.2025.06.004_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2024.121350","article-title":"Fate of sulfamethoxazole in wetland sediment under controlled redox conditions","volume":"254","author":"He","year":"2024","journal-title":"Water Res."},{"issue":"25","key":"10.1016\/j.jes.2025.06.004_bib0021","doi-asserted-by":"crossref","first-page":"8973","DOI":"10.1002\/chem.201501444","article-title":"Drug metabolism by cytochrome P450 enzymes: what distinguishes the pathways leading to substrate hydroxylation over desaturation?","volume":"21","author":"Ji","year":"2015","journal-title":"Chem. Eur. J."},{"issue":"43","key":"10.1016\/j.jes.2025.06.004_bib0022","doi-asserted-by":"crossref","first-page":"14507","DOI":"10.1039\/D1SC03489H","article-title":"MD simulations and QM\/MM calculations reveal the key mechanistic elements which are responsible for the efficient C-H amination reaction performed by a bioengineered P450 enzyme","volume":"12","author":"Kalita","year":"2021","journal-title":"Chem. Sci."},{"issue":"2","key":"10.1016\/j.jes.2025.06.004_bib0023","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1021\/acscatal.4c06278","article-title":"An asynchronous, concerted mechanism for cytochrome P450-catalyzed dehydrogenation: a combined deuterium labeling and QM\/MM study","volume":"15","author":"Kirk","year":"2025","journal-title":"ACS Catal."},{"issue":"10","key":"10.1016\/j.jes.2025.06.004_bib0024","doi-asserted-by":"crossref","first-page":"3466","DOI":"10.1039\/D3SC05974J","article-title":"Unusual catalytic strategy by non-heme Fe(II)\/2-oxoglutarate-dependent aspartyl hydroxylase AspH","volume":"15","author":"Krishnan","year":"2024","journal-title":"Chem. Sci."},{"issue":"25","key":"10.1016\/j.jes.2025.06.004_bib0025","doi-asserted-by":"crossref","first-page":"6552","DOI":"10.1021\/bi800328s","article-title":"Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1","volume":"47","author":"K\u00fchnel","year":"2008","journal-title":"Biochemistry"},{"issue":"11","key":"10.1016\/j.jes.2025.06.004_bib0026","doi-asserted-by":"crossref","first-page":"9761","DOI":"10.1074\/jbc.M211575200","article-title":"Substrate recognition and molecular mechanism of fatty acid hydroxylation by cytochrome P450 from Bacillus subtilis: crystallographic, spectroscopic, and mutational studies","volume":"278","author":"Lee","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jes.2025.06.004_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.104919","article-title":"Spatial and seasonal variations of antibiotics in river waters in the Haihe River Catchment in China and ecotoxicological risk assessment","volume":"130","author":"Lei","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.jes.2025.06.004_bib0028","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jes.2024.05.015","article-title":"Porphyrinic based hydrogen-bonded organic framework\/TiO2 nanocomposites for efficient photocatalytic degradation of sulfadiazine","volume":"152","author":"Li","year":"2025","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.jes.2025.06.004_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.108140","article-title":"Screening of priority antibiotics in Chinese seawater based on the persistence, bioaccumulation, toxicity and resistance","volume":"179","author":"Li","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.jes.2025.06.004_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126994","article-title":"Effect of pig manure-derived sulfadiazine on species distribution and bioactivities of soil ammonia-oxidizing microorganisms after fertilization","volume":"423","author":"Li","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.jes.2025.06.004_bib0031","article-title":"Rational design of CYP120A1 variants and eco-friendly alternatives for enhanced bioremediation of sulfonamide antibiotics","volume":"6","author":"Li","year":"2025","journal-title":"J. Hazard. Mater. Lett."},{"issue":"10","key":"10.1016\/j.jes.2025.06.004_bib0032","doi-asserted-by":"crossref","first-page":"7893","DOI":"10.1021\/acscatal.4c02215","article-title":"Local electric fields drives the proton-coupled electron transfer within cytochrome P450 reductase","volume":"14","author":"Li","year":"2024","journal-title":"ACS Catal."},{"issue":"6","key":"10.1016\/j.jes.2025.06.004_bib0033","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1021\/acs.chemrestox.5b00514","article-title":"Quantum mechanics\/molecular mechanics modeling of drug metabolism: mexiletine N-hydroxylation by cytochrome P450 1A2","volume":"29","author":"Lonsdale","year":"2016","journal-title":"Chem. Res. Toxicol."},{"issue":"8","key":"10.1016\/j.jes.2025.06.004_bib0034","doi-asserted-by":"crossref","DOI":"10.1063\/5.0216272","article-title":"A comprehensive electron wavefunction analysis toolbox for chemists, Multiwfn","volume":"161","author":"Lu","year":"2024","journal-title":"J. Chem. Phys."},{"issue":"5","key":"10.1016\/j.jes.2025.06.004_bib0035","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1002\/jcc.22885","article-title":"Multiwfn: a multifunctional wavefunction analyzer","volume":"33","author":"Lu","year":"2012","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.jes.2025.06.004_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2024.119225","article-title":"Exploring the influence of sulfadiazine-induced stress on antibiotic removal and transformation pathway using microalgae Chlorella sp","volume":"256","author":"Ma","year":"2024","journal-title":"Environ. Res."},{"issue":"43","key":"10.1016\/j.jes.2025.06.004_bib0037","doi-asserted-by":"crossref","first-page":"17236","DOI":"10.1021\/jacs.9b08109","article-title":"Mechanisms for hydrogen-atom abstraction by mononuclear copper(III) cores: hydrogen-atom transfer or concerted proton coupled electron transfer?","volume":"141","author":"Mandal","year":"2019","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"10.1016\/j.jes.2025.06.004_bib0038","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/wcms.1163","article-title":"ChemShell-a modular software package for QM\/MM simulations","volume":"4","author":"Metz","year":"2014","journal-title":"Wires. Comput. Mol. Sci."},{"issue":"44","key":"10.1016\/j.jes.2025.06.004_bib0039","doi-asserted-by":"crossref","first-page":"20484","DOI":"10.1021\/jacs.2c09263","article-title":"How do preorganized electric fields function in catalytic cycles? The case of the enzyme tyrosine hydroxylase","volume":"144","author":"Peng","year":"2022","journal-title":"J. Am. Chem. Soc."},{"issue":"16","key":"10.1016\/j.jes.2025.06.004_bib0040","doi-asserted-by":"crossref","first-page":"10416","DOI":"10.1021\/acscatal.1c02444","article-title":"Reaction mechanism of MHETase, a PET degrading enzyme","volume":"11","author":"Pinto","year":"2021","journal-title":"ACS Catal."},{"issue":"20","key":"10.1016\/j.jes.2025.06.004_bib0041","doi-asserted-by":"crossref","DOI":"10.1002\/qua.27193","article-title":"Regioselectivity of C-H activation in cytochrome P450-catalyzed intramolecular cyclization of alkylamine compounds","volume":"123","author":"Qin","year":"2023","journal-title":"Int. J. Quantum Chem."},{"issue":"23","key":"10.1016\/j.jes.2025.06.004_bib0042","doi-asserted-by":"crossref","first-page":"8773","DOI":"10.3390\/ijerph17238773","article-title":"The toxicity exerted by the antibiotic sulfadiazine on the growth of soil bacterial communities may increase over time","volume":"17","author":"Sant\u00e1s-Miguel","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"20","key":"10.1016\/j.jes.2025.06.004_bib0043","doi-asserted-by":"crossref","first-page":"7977","DOI":"10.1021\/ja201665x","article-title":"The directive of the protein: how does cytochrome P450 select the mechanism of dopamine formation?","volume":"133","author":"Schyman","year":"2011","journal-title":"J. Am. Chem. Soc."},{"issue":"4","key":"10.1016\/j.jes.2025.06.004_bib0044","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1021\/tx500371a","article-title":"Mechanism of the N-hydroxylation of primary and secondary amines by cytochrome P450","volume":"28","author":"Seger","year":"2015","journal-title":"Chem. Res. Toxicol."},{"issue":"2","key":"10.1016\/j.jes.2025.06.004_bib0045","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1021\/cr900121s","article-title":"P450 enzymes: their structure, reactivity, and selectivity-modeled by QM\/MM calculations","volume":"110","author":"Shaik","year":"2010","journal-title":"Chem. Rev."},{"issue":"6","key":"10.1016\/j.jes.2025.06.004_bib0046","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1021\/cr030722j","article-title":"Theoretical perspective on the structure and mechanism of cytochrome P450 enzymes","volume":"105","author":"Shaik","year":"2005","journal-title":"Chem. Rev."},{"issue":"3","key":"10.1016\/j.jes.2025.06.004_bib0047","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0263-7855(96)00043-4","article-title":"DL_POLA_2.0: a general-purpose parallel molecular dynamics simulation package","volume":"14","author":"Smith","year":"1996","journal-title":"J. Mol. Graph."},{"issue":"7","key":"10.1016\/j.jes.2025.06.004_bib0048","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1002\/jcc.540150702","article-title":"New spherical-cutoff methods for long-range forces in macromolecular simulation","volume":"15","author":"Steinbach","year":"1994","journal-title":"J. Comput. Chem."},{"issue":"2","key":"10.1016\/j.jes.2025.06.004_bib0049","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","article-title":"AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading","volume":"31","author":"Trott","year":"2010","journal-title":"J. Comput. Chem."},{"issue":"45","key":"10.1016\/j.jes.2025.06.004_bib0050","doi-asserted-by":"crossref","first-page":"9697","DOI":"10.1021\/acs.jpcb.3c04293","article-title":"Catalytic mechanism of collagen hydrolysis by zinc(II)-dependent matrix metalloproteinase-1","volume":"127","author":"Varghese","year":"2023","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.jes.2025.06.004_bib0051","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.133471","article-title":"Occurrence, spatiotemporal trends, fate, and treatment technologies for microplastics and organic contaminants in biosolids: a review","volume":"466","author":"Vo","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.jes.2025.06.004_bib0052","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132811","article-title":"Biodegradation of sulfadiazine by ryegrass (Lolium perenne L.) in a soil system: analysis of detoxification mechanisms, transcriptome, and bacterial communities","volume":"462","author":"Wang","year":"2024","journal-title":"J. Hazard. Mater."},{"issue":"7","key":"10.1016\/j.jes.2025.06.004_bib0053","doi-asserted-by":"crossref","first-page":"4175","DOI":"10.1021\/acscatal.5b00510","article-title":"Estrogen formation via H-abstraction from the O-H bond of gem-diol by compound i in the reaction of CYP19A1: mechanistic scenario derived from multiscale QM\/MM calculations","volume":"5","author":"Xu","year":"2015","journal-title":"ACS Catal."},{"key":"10.1016\/j.jes.2025.06.004_bib0054","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jes.2023.07.023","article-title":"Biodegradation pathway and mechanism of tri (2-chloropropyl) phosphate by Providencia rettgeri","volume":"144","author":"Ye","year":"2024","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.jes.2025.06.004_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.131939","article-title":"Synergistic degradation of Azure B and sulfanilamide antibiotics by the white-rot fungus Trametes versicolor with an activated ligninolytic enzyme system","volume":"458","author":"Zhang","year":"2023","journal-title":"J. Hazard. Mater."},{"issue":"14","key":"10.1016\/j.jes.2025.06.004_bib0056","doi-asserted-by":"crossref","first-page":"8774","DOI":"10.1021\/acscatal.1c02068","article-title":"H-bonding networks dictate the molecular mechanism of H2O2 activation by P450","volume":"11","author":"Zhang","year":"2021","journal-title":"ACS Catal."},{"key":"10.1016\/j.jes.2025.06.004_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127248","article-title":"Insights into removal of sulfonamides in anaerobic activated sludge system: mechanisms, degradation pathways and stress responses","volume":"423","author":"Zhao","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"35","key":"10.1016\/j.jes.2025.06.004_bib0058","doi-asserted-by":"crossref","first-page":"15681","DOI":"10.1021\/acs.est.3c10482","article-title":"Semirational design strategy to enhance the thermostability and catalytic activity of cytochrome P450 105D7 for the degradation of the pharmaceutically active compounds: diclofenac","volume":"58","author":"Zhu","year":"2024","journal-title":"Environ. Sci. Technol."},{"issue":"11","key":"10.1016\/j.jes.2025.06.004_bib0059","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1002\/jcc.21816","article-title":"Swissparam: a fast force field generation tool for small organic molecules","volume":"32","author":"Zoete","year":"2011","journal-title":"J. Comput. Chem."}],"container-title":["Journal of Environmental Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1001074225003602?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1001074225003602?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T11:37:03Z","timestamp":1766835423000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1001074225003602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":59,"alternative-id":["S1001074225003602"],"URL":"https:\/\/doi.org\/10.1016\/j.jes.2025.06.004","relation":{},"ISSN":["1001-0742"],"issn-type":[{"value":"1001-0742","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular mechanisms of sulfadiazine biodegradation: The impact of intrinsic electric fields","name":"articletitle","label":"Article Title"},{"value":"Journal of Environmental Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jes.2025.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}