{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:21:12Z","timestamp":1760059272001,"version":"build-2065373602"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Equine Veterinary Science"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.jevs.2019.102872","type":"journal-article","created":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T20:13:31Z","timestamp":1574453611000},"page":"102872","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Persistent Bilateral Mydriasis Associated With a Pituitary Adenoma in a Horse"],"prefix":"10.1016","volume":"85","author":[{"given":"Lisa","family":"Allnoch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Peters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Wiemer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Wohlsein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"year":"2017","series-title":"Equine Ophthalmology. Equine Ophthalmology","author":"Beltran","key":"10.1016\/j.jevs.2019.102872_bib1"},{"key":"10.1016\/j.jevs.2019.102872_bib2","series-title":"AAEP Proceedings","first-page":"353","article-title":"Diseases of the brainstem and cranial nerves of the horse: relevant examination techniques and illustrative video segments","volume":"57","author":"MacKay","year":"2011"},{"year":"2003","series-title":"Lehrbuch der Anatomie der Haustiere Band IV: Nervensystem, Sinnesorgane","author":"Nickel","key":"10.1016\/j.jevs.2019.102872_bib3"},{"key":"10.1016\/j.jevs.2019.102872_bib4","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/j.1740-8261.2000.tb01885.x","article-title":"Magnetic resonance diagnosis: cavernous sinus syndrome in a dog","volume":"41","author":"Fransson","year":"2000","journal-title":"Vet Radiol Ultrasound"},{"key":"10.1016\/j.jevs.2019.102872_bib5","doi-asserted-by":"crossref","first-page":"186","DOI":"10.4314\/ovj.v8i2.12","article-title":"Cavernous sinus syndrome in dogs and cats: case series (2002-2015)","volume":"8","author":"Jones","year":"2018","journal-title":"Open Vet J"},{"key":"10.1016\/j.jevs.2019.102872_bib6","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1111\/j.2042-3306.2011.00444.x","article-title":"Circannual variation in plasma adrenocorticotropic hormone concentrations in the UK in normal horses and ponies, and those with pituitary pars intermedia dysfunction","volume":"44","author":"Copas","year":"2012","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jevs.2019.102872_bib7","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.cveq.2010.12.007","article-title":"Equine pituitary pars intermedia dysfunction","volume":"27","author":"McFarlane","year":"2011","journal-title":"Vet Clin North Am Equine Pract"},{"key":"10.1016\/j.jevs.2019.102872_bib8","series-title":"Romeis Mikroskopische Technik","first-page":"198","author":"Riedelsheimer","year":"2010"},{"key":"10.1016\/j.jevs.2019.102872_bib9","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.vetimm.2017.01.001","article-title":"Evaluation of a panel of antibodies for the immunohistochemical identification of immune cells in paraffin-embedded lymphoid tissues of new- and old-world camelids","volume":"184","author":"Uhde","year":"2017","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.jevs.2019.102872_bib10","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s004010050518","article-title":"Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper virus encephalitis","volume":"92","author":"Alldinger","year":"1996","journal-title":"Acta Neuropathol"},{"volume":"3","year":"2016","author":"Jubb","key":"10.1016\/j.jevs.2019.102872_bib11"},{"key":"10.1016\/j.jevs.2019.102872_bib12","doi-asserted-by":"crossref","first-page":"3791","DOI":"10.1210\/en.2018-00726","article-title":"Dysregulation of cortisol Metabolism in equine pituitary pars intermedia dysfunction","volume":"159","author":"Morgan","year":"2018","journal-title":"Endocrinology"},{"key":"10.1016\/j.jevs.2019.102872_bib13","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/evj.12194","article-title":"Current status and future directions: equine pituitary pars intermedia dysfunction and equine metabolic syndrome","volume":"46","author":"Sojka-Kritchevsky","year":"2014","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jevs.2019.102872_bib14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0021-9975(08)80260-5","article-title":"Equine pituitary adenoma: a functional and morphological study","volume":"109","author":"Boujon","year":"1993","journal-title":"J\u00a0Comp Pathol"},{"key":"10.1016\/j.jevs.2019.102872_bib15","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1210\/endo-110-4-1430","article-title":"Equine Cushing\u2019s disease: plasma immunoreactive proopiolipomelanocortin peptide and cortisol levels basally and in response to diagnostic tests","volume":"110","author":"Orth","year":"1982","journal-title":"Endocrinology"},{"key":"10.1016\/j.jevs.2019.102872_bib16","first-page":"742","article-title":"Treatment with pergolide or cyproheptadine of pituitary pars intermedia dysfunction (equine Cushing\u2019s disease)","volume":"16","author":"Donaldson","year":"2002","journal-title":"J\u00a0Vet Intern Med"},{"key":"10.1016\/j.jevs.2019.102872_bib17","doi-asserted-by":"crossref","first-page":"679","DOI":"10.2746\/042516402776250333","article-title":"Plasma adrenocorticotropin (ACTH) concentrations and clinical response in horses treated for equine Cushing\u2019s disease with cyproheptadine or pergolide","volume":"34","author":"Perkins","year":"2002","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jevs.2019.102872_bib18","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1111\/j.1939-1676.2007.tb03060.x","article-title":"Survival, neurologic response, and prognostic factors in dogs with pituitary masses treated with radiation therapy and untreated dogs","volume":"21","author":"Kent","year":"2007","journal-title":"J\u00a0Vet Intern Med"},{"key":"10.1016\/j.jevs.2019.102872_bib19","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1292\/jvms.13-0373","article-title":"A\u00a0case report of feline pituitary carcinoma with hypercortisolism","volume":"76","author":"Kimitsuki","year":"2014","journal-title":"J\u00a0Vet Med Sci"},{"year":"2014","series-title":"Veterinary neuroanatomy and clinical Neurology","author":"de Lahunta","key":"10.1016\/j.jevs.2019.102872_bib20"},{"key":"10.1016\/j.jevs.2019.102872_bib21","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1097\/MD.0b013e318156c67f","article-title":"Cavernous sinus syndrome: a series of 126 patients","volume":"86","author":"Fernandez","year":"2007","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jevs.2019.102872_bib22","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1939-1676.1996.tb02029.x","article-title":"A\u00a0retrospective study of cavernous sinus syndrome in 4 dogs and 8 cats","volume":"10","author":"Theisen","year":"1996","journal-title":"J\u00a0Vet Intern Med"},{"key":"10.1016\/j.jevs.2019.102872_bib23","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/vop.12127","article-title":"Cavernous sinus syndrome in a Holstein bull","volume":"18","author":"Jacob","year":"2015","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2019.102872_bib24","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/vru.12478","article-title":"Clinical and Magnetic Resonance Imaging features of Idiopathic oculomotor Neuropathy in 14 dogs","volume":"58","author":"Tetas Pont","year":"2017","journal-title":"Vet Radiol Ultrasound"},{"key":"10.1016\/j.jevs.2019.102872_bib25","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/vru.12676","article-title":"\u201cCavernous sinus syndrome\u201d or \u201cmiddle cranial fossa syndrome\u201d: Considerations on terminology","volume":"60","author":"Ricciardi","year":"2019","journal-title":"Vet Radiol Ultrasound"},{"key":"10.1016\/j.jevs.2019.102872_bib26","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.2460\/javma.2005.226.1105","article-title":"Bilateral cavernous sinus syndrome in dogs: 6 cases (1999-2004)","volume":"226","author":"Rossmeisl","year":"2005","journal-title":"J\u00a0Am Vet Med Assoc"},{"key":"10.1016\/j.jevs.2019.102872_bib27","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/S0195-5616(01)50011-X","article-title":"Hypophysectomy as a treatment for canine and feline Cushing\u2019s disease","volume":"31","author":"Meij","year":"2001","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"10.1016\/j.jevs.2019.102872_bib28","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0303-7207(02)00283-6","article-title":"Progress in transsphenoidal hypophysectomy for treatment of pituitary-dependent hyperadrenocorticism in dogs and cats","volume":"197","author":"Meij","year":"2002","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.jevs.2019.102872_bib29","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/01652176.2017.1415488","article-title":"Development of two surgical approaches to the pituitary gland in the Horse","volume":"38","author":"Carmalt","year":"2018","journal-title":"Vet Q"}],"container-title":["Journal of Equine Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0737080619306215?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0737080619306215?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:45:29Z","timestamp":1760031929000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0737080619306215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":29,"alternative-id":["S0737080619306215"],"URL":"https:\/\/doi.org\/10.1016\/j.jevs.2019.102872","relation":{},"ISSN":["0737-0806"],"issn-type":[{"type":"print","value":"0737-0806"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistent Bilateral Mydriasis Associated With a Pituitary Adenoma in a Horse","name":"articletitle","label":"Article Title"},{"value":"Journal of Equine Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jevs.2019.102872","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102872"}}