{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:51:46Z","timestamp":1780051906673,"version":"3.53.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Equine Veterinary Science"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.jevs.2022.104075","type":"journal-article","created":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T17:58:27Z","timestamp":1657475907000},"page":"104075","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Luteal Tissue Area and Immunoreactive Concentration of Progesterone in Plasma of Bred and Non-bred Mares"],"prefix":"10.1016","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9024-2764","authenticated-orcid":false,"given":"Ilaria","family":"Colombo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Podico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alba","family":"Rudolf-Vegas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Bauersachs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3799-6641","authenticated-orcid":false,"given":"Igor F.","family":"Canisso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jevs.2022.104075_bib0001","doi-asserted-by":"crossref","first-page":"330","DOI":"10.2527\/jas1974.382330x","article-title":"Ovarian changes during the estrous cycle and pregnancy in mares","volume":"38","author":"Squires","year":"1974","journal-title":"J Anim Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0002","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0093-691X(85)90047-0","article-title":"Embryonic loss in mares: pregnancy rate, length of interovulatory intervals, and progesterone concentrations associated with loss during days 11 to 15","volume":"24","author":"Ginther","year":"1985","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0003","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/0093-691X(87)90059-8","article-title":"Role of progesterone in mobility, fixation, orientation, and survival of the equine embryonic vesicle","volume":"27","author":"Kastelic","year":"1987","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0004","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0093-691X(83)90181-4","article-title":"Fixation and orientation of the early equine conceptus","volume":"19","author":"Ginther","year":"1983","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0005","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/0093-691X(83)90180-2","article-title":"Mobility of the early equine conceptus","volume":"19","author":"Ginther","year":"1983","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0006","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/0093-691X(84)90460-6","article-title":"Characterization of intrauterine mobility of the early equine conceptus","volume":"22","author":"Leith","year":"1984","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0007","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1007\/PL00000622","article-title":"A novel uterine lipocalin supporting pregnancy in equids","volume":"57","author":"Stewart","year":"2000","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0008","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.theriogenology.2018.11.018","article-title":"Early luteal phase progestin concentration influences endometrial function in pregnant mares","volume":"125","author":"Beyer","year":"2019","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0009","series-title":"Reproductive biology of the mare","author":"Ginther","year":"1992"},{"key":"10.1016\/j.jevs.2022.104075_bib0010","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.2042-3306.2012.00559.x","article-title":"Premature luteal regression in a pregnant mare and subsequent pregnancy maintenance with the use of oral altrenogest","volume":"45","author":"Canisso","year":"2013","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jevs.2022.104075_bib0011","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jevs.2013.10.143","article-title":"Changes accompanying spontaneous embryonic loss in nine mares during the first month of pregnancy","volume":"34","author":"Betteridge","year":"2014","journal-title":"J Equine Vet Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0012","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/j.1439-0531.2008.01167.x","article-title":"Proteins associated with the early intrauterine equine conceptus","volume":"43","author":"Hayes","year":"2008","journal-title":"Reprod Dom Anim"},{"key":"10.1016\/j.jevs.2022.104075_bib0013","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1071\/RD11132","article-title":"Relationship between the timing of prostaglandin-induced luteolysis and effects on the conceptus during early pregnancy in mares","volume":"24","author":"Betteridge","year":"2012","journal-title":"Reprod Fertil Dev"},{"key":"10.1016\/j.jevs.2022.104075_bib0014","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.anireprosci.2005.10.008","article-title":"Controlling interrelationships of progesterone\/LH and estradiol\/LH in mares","volume":"95","author":"Ginther","year":"2006","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0015","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.anireprosci.2006.05.018","article-title":"Luteal blood flow and progesterone production in mares","volume":"99","author":"Ginther","year":"2007","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0016","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.tvjl.2012.12.028","article-title":"Pre-ovulatory progestagen treatment in mares fails to delay ovulation","volume":"197","author":"Canisso","year":"2013","journal-title":"Vet J"},{"key":"10.1016\/j.jevs.2022.104075_bib0017","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0093-691X(99)00154-5","article-title":"Relationship between ultrasonic characteristics of the corpus luteum, plasma progesterone concentration and early pregnancy diagnosis in friesian mares","volume":"52","author":"Sevinga","year":"1999","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0018","doi-asserted-by":"crossref","first-page":"512","DOI":"10.17221\/7046-CJAS","article-title":"The luteal blood flow, area and pixel intensity of corpus luteum, levels of progesterone in pregnant and nonpregnant mares in the period of 16 days after ovulation","volume":"58","author":"\u0160ichta\u0159","year":"2013","journal-title":"Czech J Anim Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0019","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.theriogenology.2021.02.004","article-title":"Concentrations of progesterone and a PGF2\u03b1 metabolite during the interovulatory interval compared to the corresponding days of pregnancy in mares","volume":"165","author":"Castro","year":"2021","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0020","first-page":"445","article-title":"Effect of uterine inflammation and ultrasonically-detected uterine pathology on fertility in the mare","volume":"35","author":"Adams","year":"1987","journal-title":"J Reprod Fertil Suppl"},{"key":"10.1016\/j.jevs.2022.104075_bib0021","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1530\/jrf.0.0950339","article-title":"Role of the embryonic vesicle and progesterone in embryonic loss in mares","volume":"95","author":"Bergfelt","year":"1992","journal-title":"Reprod"},{"key":"10.1016\/j.jevs.2022.104075_bib0022","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jevs.2014.12.002","article-title":"Equine infectious endometritis\u2014clinical and subclinical cases","volume":"35","author":"Rasmussen","year":"2015","journal-title":"J Equine Vet Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0023","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.jevs.2008.10.001","article-title":"Early embryonic loss in the mare","volume":"28","author":"Vanderwall","year":"2008","journal-title":"J Equine Vet Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0024","first-page":"723","article-title":"Changes in various endometrial proteins during cloprostenol-induced failure of early pregnancy in mares","volume":"9","author":"Hayes","year":"2012","journal-title":"Anim Reprod"},{"key":"10.1016\/j.jevs.2022.104075_bib0025","doi-asserted-by":"crossref","first-page":"22293","DOI":"10.1038\/s41598-021-01785-3","article-title":"Spatiotemporal endometrial transcriptome analysis revealed the luminal epithelium as key player during initial maternal recognition of pregnancy in the mare","volume":"11","author":"Rudolf Vegas","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.jevs.2022.104075_bib0026","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1177\/875647939000600106","article-title":"Interpretation of the correlation coefficient: a basic review","volume":"6","author":"Taylor","year":"1990","journal-title":"J Diagn Med Son"},{"key":"10.1016\/j.jevs.2022.104075_bib0027","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.theriogenology.2020.01.076","article-title":"Insights into nerve growth factor-\u03b2 role in bovine reproduction - Review","volume":"150","author":"Lima","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0028","first-page":"171","article-title":"Relationship between the morphology of and progesterone production by the corpus luteum of the mare","author":"van Niekerk","year":"1975","journal-title":"J Reprod Fertil Supplement"},{"key":"10.1016\/j.jevs.2022.104075_bib0029","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1095\/biolreprod.105.040097","article-title":"Ovulation-inducing factor in the seminal plasma of Alpacas and Llamas1","volume":"73","author":"Adams","year":"2005","journal-title":"Biol Reprod"},{"key":"10.1016\/j.jevs.2022.104075_bib0030","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.theriogenology.2017.10.007","article-title":"Nerve Growth Factor-Beta, purified from bull seminal plasma, enhances corpus luteum formation and conceptus development in Bos taurus cows","volume":"106","author":"Stewart","year":"2018","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0031","doi-asserted-by":"crossref","first-page":"70","DOI":"10.2460\/javma.245.1.70","article-title":"Success rates of various techniques for reduction of twin pregnancy in mares","volume":"245","author":"Tan","year":"2014","journal-title":"JAVMA"},{"key":"10.1016\/j.jevs.2022.104075_bib0032","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.anireprosci.2017.09.003","article-title":"Pre-ovulatory follicle affects corpus luteum diameter, blood flow, and progesterone production in mares","volume":"187","author":"Ishak","year":"2017","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0033","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.theriogenology.2007.11.019","article-title":"Repeatability of pre-ovulatory follicular diameter and uterine edema pattern in two consecutive cycles in the mare and how they are influenced by ovulation inductors","volume":"69","author":"Cuervo-Arango","year":"2008","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.jevs.2021.103691","article-title":"The combination of hCG and GnRH analog to hasten ovulation in mares does not change luteal function and pregnancy outcome in embryo recipient mares","volume":"105","author":"Segabinazzi","year":"2021","journal-title":"J Equine Vet Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0035","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.theriogenology.2022.03.003","article-title":"Ovulatory response to GnRH agonist during early and late fall in mares","volume":"185","author":"Spencer","year":"2022","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0036","series-title":"Equine breeding management and artificial insemination (second edition)","first-page":"1","article-title":"Uterine edema in the mare","author":"Samper","year":"2009"},{"key":"10.1016\/j.jevs.2022.104075_sbref0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.jevs.2021.103669","article-title":"Artificial long estrus protocols administered prior to progesterone increase endometrial uterocalin expression in anestrous mares","volume":"103","author":"Silva","year":"2021","journal-title":"J Equine Vet Sci"},{"key":"10.1016\/j.jevs.2022.104075_bib0038","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.theriogenology.2020.12.029","article-title":"Intrauterine infusion of killed semen adversely affects uterine blood flow and endometrial gene expression of inflammatory cytokines in mares susceptible to persistent breeding-induced endometritis","volume":"163","author":"L\u00fcttgenau","year":"2021","journal-title":"Theriogenology"},{"key":"10.1016\/j.jevs.2022.104075_bib0039","doi-asserted-by":"crossref","DOI":"10.3390\/antibiotics10050490","article-title":"Intrauterine blood plasma platelet-therapy mitigates persistent breeding-induced endometritis, reduces uterine infections, and improves embryo recovery in mares","volume":"10","author":"Segabinazzi","year":"2021","journal-title":"Antibiotics"}],"container-title":["Journal of Equine Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073708062200212X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073708062200212X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:52:53Z","timestamp":1760032373000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073708062200212X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":39,"alternative-id":["S073708062200212X"],"URL":"https:\/\/doi.org\/10.1016\/j.jevs.2022.104075","relation":{},"ISSN":["0737-0806"],"issn-type":[{"value":"0737-0806","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Luteal Tissue Area and Immunoreactive Concentration of Progesterone in Plasma of Bred and Non-bred Mares","name":"articletitle","label":"Article Title"},{"value":"Journal of Equine Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jevs.2022.104075","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104075"}}