{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:47:14Z","timestamp":1761976034423,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Equine Veterinary Science"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jevs.2023.104910","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T19:52:09Z","timestamp":1692820329000},"page":"104910","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Corneal Ulcers in Critically Ill Foals in Intensive Care: Case Series of Standard Treatment and Corneal Cross-Linking"],"prefix":"10.1016","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4444-8061","authenticated-orcid":false,"given":"Ilaria","family":"Imposimato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jole","family":"Mariella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1645-2111","authenticated-orcid":false,"given":"Francesca","family":"Freccero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo","family":"Gialletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jevs.2023.104910_bib0001","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.2042-3306.1983.tb04579.x","article-title":"Ocular trauma in the horse","volume":"15","author":"Brooks","year":"1992","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jevs.2023.104910_bib0002","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/vop.12701","article-title":"Equine infectious keratitis in Finland: associated microbial isolates and susceptibility profiles","volume":"23","author":"Mustikka","year":"2019","journal-title":"Vet Ophthalmology"},{"key":"10.1016\/j.jevs.2023.104910_bib0003","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/vop.12297","article-title":"A retrospective analysis of environmental risk factors for the diagnosis of deep stromal abscess in 390 horses in North Central Florida from 1991 to 2013","volume":"19","author":"Proietto","year":"2016","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0004","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1463-5224.2010.00767.x","article-title":"Ulcerative keratitis in thoroughbred racehorses in Japan from 1997 to 2008","volume":"13","author":"Wada","year":"2010","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0005","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/j.1463-5224.2012.01063.x","article-title":"Ocular abnormalities in healthy Standardbred foals","volume":"16","author":"Barsotti","year":"2012","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0006","first-page":"134","article-title":"Corneal sensitivity and tear production in hospitalized neonatal foals","volume":"23","author":"Clark","year":"1996","journal-title":"Proc Am Coll Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0007","series-title":"Equine Ophthalmology","article-title":"Diseases of the cornea","author":"Brooks","year":"2017"},{"key":"10.1016\/j.jevs.2023.104910_bib0008","first-page":"1","article-title":"Morphological and immunohistochemical characteristics of the equine corneal epithelium","volume":"00","author":"Kammergruber","year":"2019","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.jevs.2022.104050","article-title":"Lacrimal secretion variation and menace response appearance in healthy standardbred foals from birth to four weeks of age","volume":"116","author":"Nardi","year":"2022","journal-title":"J Equine Vet Sci"},{"key":"10.1016\/j.jevs.2023.104910_bib0010","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.2042-3292.2010.00163.x","article-title":"Ocular findings in healthy newborn foals according to age","volume":"23","author":"Leiva","year":"2011","journal-title":"Equine Vet Educ"},{"key":"10.1016\/j.jevs.2023.104910_bib0011","series-title":"Equine Neonatal Medicine: A Case-Based Approach 2006 14. North Grafton","first-page":"262","article-title":"Ophthalmologic disorders of the neonate","author":"Jurk","year":"2006"},{"key":"10.1016\/j.jevs.2023.104910_bib0012","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1746-6148-9-128","article-title":"Corneal cross-linking in 9 horses with ulcerative keratitis","volume":"9","author":"Hellander-Edman","year":"2013","journal-title":"BMC Vet Res"},{"key":"10.1016\/j.jevs.2023.104910_bib0013","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/vop.12103","article-title":"Equine deep stromal abscesses (51 cases - 2004-2009)\u2013Part 1: the clinical aspects with attention to the duration of the corneal disease, treatment history, clinical appearance, and microbiology results","volume":"17","author":"de Linde Henriksen","year":"2014","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0014","doi-asserted-by":"crossref","first-page":"321","DOI":"10.17221\/60\/2020-VETMED","article-title":"Efficacy of riboflavin\/UV-A corneal phototherapy as stand-alone treatment for ulcerative keratitis in horses","volume":"66","author":"Marchegiani","year":"2021","journal-title":"Vet Med-Czech"},{"key":"10.1016\/j.jevs.2023.104910_bib0015","first-page":"1","article-title":"Corneal cross-linking as a treatment for corneal dystrophy with secondary bacterial infection in a Friesian horse","volume":"00","author":"Casola","year":"2020","journal-title":"Clin Case Rep"},{"key":"10.1016\/j.jevs.2023.104910_bib0016","doi-asserted-by":"crossref","DOI":"10.1136\/bmjophth-2017-000112","article-title":"Expert practice patterns and opinions on corneal cross-linking for infectious keratitis","volume":"3","author":"Hsia","year":"2018","journal-title":"BMJ Open Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0017","series-title":"Corneal Collagen Cross Linking","first-page":"63","article-title":"Fundamentals of corneal collagen cross linking","author":"Mc Quais","year":"2017"},{"key":"10.1016\/j.jevs.2023.104910_bib0018","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/ICO.0000000000000644","article-title":"Corneal collagen cross-linking for infectious keratitis: a systematic review and meta-analysis","volume":"35","author":"Papaioannou","year":"2016","journal-title":"Cornea"},{"key":"10.1016\/j.jevs.2023.104910_bib0019","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/ICO.0000000000001165","article-title":"Comparison of the conventional dresden protocol and accelerated protocol with higher ultraviolet intensity in corneal collagen cross-linking for keratoconus","volume":"36","author":"Choi","year":"2017","journal-title":"Cornea"},{"key":"10.1016\/j.jevs.2023.104910_bib0020","doi-asserted-by":"crossref","first-page":"730","DOI":"10.3390\/ani10040730","article-title":"An assay system to evaluate riboflavin\/UV-A corneal phototherapy efficacy in a porcine corneal organ culture model","volume":"10","author":"Perazzi","year":"2020","journal-title":"Animals"},{"key":"10.1016\/j.jevs.2023.104910_bib0021","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s40123-019-00210-3","article-title":"Combined protocols for corneal collagen cross-linking with photorefractive surgery for refractive management of keratoconus: update on techniques and review of literature","volume":"8","author":"Zhu","year":"2019","journal-title":"Ophthalmol Ther"},{"key":"10.1016\/j.jevs.2023.104910_bib0022","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1111\/vop.12662","article-title":"Corneal cross-linking (CXL)- a clinical study to evaluate CXL as a treatment in comparison with medical treatment for ulcerative keratitis in horses","volume":"22","author":"Hellander-Edman","year":"2019","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0023","doi-asserted-by":"crossref","first-page":"950","DOI":"10.3390\/ijms21030950","article-title":"Riboflavin: the health benefits of a forgotten natural vitamin","volume":"21","author":"Suwannasom","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jevs.2023.104910_bib0024","doi-asserted-by":"crossref","first-page":"574","DOI":"10.18240\/ijo.2020.04.07","article-title":"Collagen crosslinking with photoactivated riboflavin in advanced infectious keratitis with corneal melting: Electrophysiological Study","volume":"13","author":"Awad","year":"2020","journal-title":"Int J Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0025","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1111\/vop.12772","article-title":"Clinical characteristics and treatment of spontaneous chronic corneal epithelial defects (SCCEDs) with diamond burr debridement","volume":"23","author":"Hung","year":"2020","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2023.104910_bib0026","article-title":"Neonatal corneal ulcer secondary to congenital entropion","volume":"25","author":"Redd","year":"2022","journal-title":"Am J Ophthalmol Case Rep"},{"key":"10.1016\/j.jevs.2023.104910_bib0027","series-title":"Equine ophthalmology","first-page":"202","author":"Gilger","year":"2017"},{"key":"10.1016\/j.jevs.2023.104910_bib0028","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1186\/s12917-018-1598-6","article-title":"Conjunctival aerobic bacterial flora in healthy Silesian foals and adult horses in Poland","volume":"14","author":"Zak","year":"2018","journal-title":"BMC Vet Res"},{"key":"10.1016\/j.jevs.2023.104910_bib0029","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.cveq.2019.03.004","article-title":"Equine neonatal encephalopathy: facts, evidence, and opinions","volume":"35","author":"Toribio","year":"2019","journal-title":"Vet Clin North Am Equine Pract"},{"issue":"21","key":"10.1016\/j.jevs.2023.104910_bib0030","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.3390\/ani12212939","article-title":"Non-steroidal anti-inflammatory drugs and associated toxicities in horses","volume":"12","author":"Flood","year":"2022","journal-title":"Animals (Basel)"}],"container-title":["Journal of Equine Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0737080623007268?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0737080623007268?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:54:52Z","timestamp":1760032492000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0737080623007268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":30,"alternative-id":["S0737080623007268"],"URL":"https:\/\/doi.org\/10.1016\/j.jevs.2023.104910","relation":{},"ISSN":["0737-0806"],"issn-type":[{"type":"print","value":"0737-0806"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Corneal Ulcers in Critically Ill Foals in Intensive Care: Case Series of Standard Treatment and Corneal Cross-Linking","name":"articletitle","label":"Article Title"},{"value":"Journal of Equine Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jevs.2023.104910","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104910"}}