{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T20:11:02Z","timestamp":1779826262904,"version":"3.53.1"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Fundacao para a Ciencia e a Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Equine Veterinary Science"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jevs.2026.105880","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T15:43:04Z","timestamp":1775230984000},"page":"105880","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Evaluation of episcleral silicone matrix cyclosporine implants for presumed equine immune-mediated keratitis: a retrospective study"],"prefix":"10.1016","volume":"162","author":[{"given":"Emma","family":"Bruneel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanguy","family":"Hermange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Michel","family":"Casamatta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3525-795X","authenticated-orcid":false,"given":"Alexandre","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7328-2123","authenticated-orcid":false,"given":"Jos\u00e9","family":"Pimenta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1143-2461","authenticated-orcid":false,"given":"Ana Rita","family":"Caseiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jevs.2026.105880_bib0001","series-title":"Equine ophthalmology","article-title":"Diseases of the equine cornea","author":"Brooks","year":"2022"},{"key":"10.1016\/j.jevs.2026.105880_bib0002","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1463-5224.2009.00740.x","article-title":"Equine immune-mediated keratopathies","volume":"12","author":"Matthews","year":"2009","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2026.105880_bib0003","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.2042-3306.2010.tb05632.x","article-title":"Equine immune-mediated keratopathies","volume":"37","author":"Matthews","year":"2010","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jevs.2026.105880_bib0004","first-page":"239","article-title":"Immune-mediated keratitis in horses: 19 cases (1998-2004)","volume":"4","author":"Gilger","year":"2005","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2026.105880_bib0005","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/evj.14213","article-title":"Clinical features and outcomes of horses presenting with presumed equine immune mediated keratitis to two veterinary hospitals in the United Kingdom and Finland: 94 cases (2009\u20132021)","volume":"57","author":"Preston","year":"2025","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jevs.2026.105880_bib0006","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.2460\/ajvr.73.7.1067","article-title":"Immunohistochemical and immunopathologic characterization of superficial stromal immune-mediated keratitis in horses","volume":"73","author":"Pate","year":"2012","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.jevs.2026.105880_bib0007","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.2042-3306.1995.tb04066.x","article-title":"Ophthalmic cyclosporine in equine keratitis and keratouveitis: 11 cases","volume":"27","author":"Gratzek","year":"1995","journal-title":"Equine Vet J"},{"key":"10.1016\/j.jevs.2026.105880_bib0008","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/vop.12677","article-title":"Laser scanning in vivo confocal microscopic characterization of equine immune-mediated keratitis","volume":"23","author":"Ledbetter","year":"2020","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2026.105880_bib0009","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.vetimm.2017.04.002","article-title":"Investigation of corneal autoantibodies in horses with immune mediated keratitis (IMMK)","volume":"187","author":"Braus","year":"2017","journal-title":"Vet Immunol Immunopathol"},{"key":"10.1016\/j.jevs.2026.105880_bib0010","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1463-5224.2008.00635.x","article-title":"An overview of recent developments in corneal immunobiology: potential relevance in the etiogenesis of corneal disease in the horse","volume":"11","author":"Matthews","year":"2008","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2026.105880_bib0011","series-title":"Equine ophthalmology","article-title":"Equine ocular examination and treatment techniques","author":"Dwyer","year":"2022"},{"key":"10.1016\/j.jevs.2026.105880_bib0012","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/vop.12173","article-title":"Use of episcleral cyclosporine implants in dogs with keratoconjunctivitis sicca: pilot study","volume":"18","author":"Barachetti","year":"2015","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2026.105880_bib0013","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1167\/iovs.04-1076","article-title":"Preclinical evaluation of a novel episcleral cyclosporine implant for ocular graft-versus-host disease","volume":"46","author":"Kim","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jevs.2026.105880_bib0014","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1167\/iovs.06-0985","article-title":"A pharmacokinetic and safety evaluation of an episcleral cyclosporine implant for potential use in high-risk keratoplasty rejection","volume":"48","author":"Lee","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jevs.2026.105880_bib0015","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/vop.12087","article-title":"Treatment of immune-mediated keratitis in horses with episcleral silicone matrix cyclosporine delivery devices","volume":"17","author":"Gilger","year":"2014","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2026.105880_bib0016","doi-asserted-by":"crossref","unstructured":"Beech J., Zappala R.A., Smith G., Lindborg S. Schirmer tear test results in normal horses and ponies: effect of age, season, environment, sex, time of day and placement of strips. vol. 6. 2003.","DOI":"10.1046\/j.1463-5224.2003.00302.x"},{"key":"10.1016\/j.jevs.2026.105880_bib0017","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1111\/vop.12819","article-title":"Comparison of two rebound tonometers in healthy horses","volume":"23","author":"Mustikka","year":"2020","journal-title":"Vet Ophthalmol"},{"key":"10.1016\/j.jevs.2026.105880_bib0018","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/eve.12414","article-title":"Equine ophthalmic examination: routine diagnostic techniques","volume":"28","author":"Seruca","year":"2016","journal-title":"Equine Vet Educ"},{"key":"10.1016\/j.jevs.2026.105880_bib0019","series-title":"Equine ophthalmology","article-title":"Diseases of the equine vitreous and retina","author":"Allbaugh","year":"2022"},{"key":"10.1016\/j.jevs.2026.105880_bib0020","series-title":"Equine ophthalmology","article-title":"Diseases of the uvea, uveitis, and recurrent uveitis","author":"Gilger","year":"2022"},{"key":"10.1016\/j.jevs.2026.105880_bib0021","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1638\/06-021.1","article-title":"Sustained release cyclosporine therapy for bilateral keratoconjunctivitis sicca in a red wolf (Canis rufus)","volume":"37","author":"Acton","year":"2006","journal-title":"J Zoo Wildl Med"},{"key":"10.1016\/j.jevs.2026.105880_bib0022","series-title":"Veterinary Ophthalmology","first-page":"1841","article-title":"Equine Ophthalmology","author":"Plummer","year":"2020"}],"container-title":["Journal of Equine Veterinary Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0737080626001164?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0737080626001164?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T19:54:48Z","timestamp":1779825288000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0737080626001164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":22,"alternative-id":["S0737080626001164"],"URL":"https:\/\/doi.org\/10.1016\/j.jevs.2026.105880","relation":{},"ISSN":["0737-0806"],"issn-type":[{"value":"0737-0806","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of episcleral silicone matrix cyclosporine implants for presumed equine immune-mediated keratitis: a retrospective study","name":"articletitle","label":"Article Title"},{"value":"Journal of Equine Veterinary Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jevs.2026.105880","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105880"}}