{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T21:00:44Z","timestamp":1780606844825,"version":"3.54.1"},"reference-count":13,"publisher":"The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA)","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T00:00:00Z","timestamp":1502323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jfda-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food and Drug Analysis"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.jfda.2017.07.009","type":"journal-article","created":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T16:00:46Z","timestamp":1503590446000},"page":"409-415","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Study of forced degradation behavior of pramlintide acetate by HPLC and LC\u2013MS"],"prefix":"10.38212","volume":"26","author":[{"given":"Yu","family":"Yuan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Bo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng-Fu","family":"Tai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Peng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-Feng","family":"Pu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"25385","reference":[{"key":"10.1016\/j.jfda.2017.07.009_bib1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/j.1552-4604.1996.tb04147.x","article-title":"Pharmacokinetics and pharmacodynamics of AC137 (25,28,29 tripro-amylin, human) after intravenous bolus and infusion doses in patients with insulin-dependent diabetes","volume":"36","author":"Colburn","year":"1996","journal-title":"J\u00a0Clin Pharmacol"},{"key":"10.1016\/j.jfda.2017.07.009_bib2","doi-asserted-by":"crossref","first-page":"S233","DOI":"10.2337\/diabetes.53.suppl_3.S233","article-title":"Amylin agonists: a novel approach in the treatment of diabetes","volume":"53","author":"Schmitz","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.jfda.2017.07.009_bib3","doi-asserted-by":"crossref","first-page":"375","DOI":"10.2165\/0063030-200822060-00004","article-title":"Pramlintide in the treatment of diabetes mellitus","volume":"22","author":"Edelman","year":"2008","journal-title":"BioDrugs"},{"key":"10.1016\/j.jfda.2017.07.009_bib4","doi-asserted-by":"crossref","first-page":"987","DOI":"10.2337\/diacare.21.6.987","article-title":"Pramlintide, a synthetic analog of human amylin, improves the metabolic profile of patients with type 2 diabetes using insulin","volume":"21","author":"Thompson","year":"1998","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jfda.2017.07.009_bib5","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/0306-9877(91)90150-W","article-title":"Amylin and insulin co-replacement therapy for insulin-dependent (type I) diabetes mellitus","volume":"36","author":"Cooper","year":"1991","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.jfda.2017.07.009_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bpc.2016.09.007","article-title":"Amyloidogenesis of the amylin analogue pramlintide","volume":"219","author":"da Silva","year":"2016","journal-title":"Biophys Chem"},{"key":"10.1016\/j.jfda.2017.07.009_bib7","doi-asserted-by":"crossref","first-page":"78","DOI":"10.2174\/1874104501105010078","article-title":"Amylin analogues in the treatment of diabetes mellitus: medicinal chemistry and structural basis of its function","volume":"5","author":"Adeghate","year":"2011","journal-title":"Open Med Chem J"},{"key":"10.1016\/j.jfda.2017.07.009_bib8","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1124\/pr.115.010629","article-title":"Amylin: pharmacology, physiology, and clinical potential","volume":"67","author":"Hay","year":"2015","journal-title":"Pharm Rev"},{"key":"10.1016\/j.jfda.2017.07.009_bib9","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/protein\/gzp029","article-title":"Solution state structures of human pancreatic amylin and pramlintide","volume":"22","author":"Cort","year":"2009","journal-title":"Protein Eng Des Sel"},{"key":"10.1016\/j.jfda.2017.07.009_bib10","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1023\/A:1011934829263","article-title":"Isolation and identification of peptide degradation products of heat stressed pramlintide injection drug product","volume":"15","author":"Hekman","year":"1998","journal-title":"Pharm Res"},{"key":"10.1016\/j.jfda.2017.07.009_bib11","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jpha.2013.09.003","article-title":"Development of forced degradation and stability indicating studies of drugs\u2014a review","volume":"4","author":"Blessy","year":"2014","journal-title":"J Pharm Anal"},{"issue":"2","key":"10.1016\/j.jfda.2017.07.009_bib12","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jfda.2013.09.015","article-title":"Forced degradation behavior of epidepride and development of a stability-indicating method based on liquid chromatography\u2013mass spectrometry","volume":"22","author":"Chen","year":"2014","journal-title":"J Food Drug Anal"},{"key":"10.1016\/j.jfda.2017.07.009_bib13","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0731-7085(99)00075-8","article-title":"Isolation and identification of cyclic imide and deamidation products in heat stressed pramlintide injection drug product","volume":"20","author":"Hekman","year":"1999","journal-title":"J Pharm Biomed Anal"}],"container-title":["Journal of Food and Drug Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1021949817301461?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1021949817301461?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1021949817301461?httpAccept=text\/plain","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T18:18:56Z","timestamp":1666635536000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1021949817301461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S1021949817301461"],"URL":"https:\/\/doi.org\/10.1016\/j.jfda.2017.07.009","relation":{},"ISSN":["1021-9498"],"issn-type":[{"value":"1021-9498","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Study of forced degradation behavior of pramlintide acetate by HPLC and LC\u2013MS","name":"articletitle","label":"Article Title"},{"value":"Journal of Food and Drug Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jfda.2017.07.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Food and Drug Administration, Taiwan. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}