{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T08:05:06Z","timestamp":1789891506324,"version":"4.0.1"},"reference-count":42,"publisher":"The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA)","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,23]],"date-time":"2018-06-23T00:00:00Z","timestamp":1529712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"National Science Centre, Poland","doi-asserted-by":"publisher","award":["2016\/23\/D\/NZ7\/00958"],"award-info":[{"award-number":["2016\/23\/D\/NZ7\/00958"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004166","name":"Medical University of Warsaw","doi-asserted-by":"publisher","award":["FW25\/NM3\/17"],"award-info":[{"award-number":["FW25\/NM3\/17"]}],"id":[{"id":"10.13039\/501100004166","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Regional Development Fund"}],"content-domain":{"domain":["jfda-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Food and Drug Analysis"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.jfda.2018.06.005","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T13:14:17Z","timestamp":1530623657000},"page":"249-258","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"title":["In\u00a0vitro \u03b1-amylase and pancreatic lipase inhibitory activity of Cornus mas L. and Cornus alba L. fruit extracts"],"prefix":"10.38212","volume":"27","author":[{"given":"Anita","family":"\u015awierczewska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Buchholz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias F.","family":"Melzig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8159-0174","authenticated-orcid":false,"given":"Monika E.","family":"Czerwi\u0144ska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"25385","reference":[{"key":"10.1016\/j.jfda.2018.06.005_bib1","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.lfs.2005.05.094","article-title":"Anthocyanins in Cornus alternifolia, Cornus controversa, Cornus kousa and Cornus Florida fruits with health benefits","volume":"78","author":"Vareed","year":"2006","journal-title":"Life Sci"},{"key":"10.1016\/j.jfda.2018.06.005_bib2","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.foodchem.2012.02.170","article-title":"Antioxidant capacity of cornelian cherry (Cornus mas L.) \u2013 comparison between permanganate reducing antioxidant capacity and other antioxidant methods","volume":"134","author":"Popovi\u0107","year":"2012","journal-title":"Food Chem"},{"key":"10.1016\/j.jfda.2018.06.005_bib3","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1007\/s00246-013-0693-5","article-title":"Investigation of the lipid-modifying and antiinflammatory effects of Cornus mas L. supplementation on dyslipidemic children and adolescents","volume":"34","author":"Asgary","year":"2013","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jfda.2018.06.005_bib4","first-page":"929","article-title":"Effects of Cornus mas L. on blood glucose, insulin and histopathology of pancreas in alloxan-induced diabetic rats. Abstract","volume":"29","author":"Shamsi","year":"2011","journal-title":"J Isfahan Med School"},{"key":"10.1016\/j.jfda.2018.06.005_bib5","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1021\/jf0520342","article-title":"Amelioration of obesity and glucose intolerance in high-fat-fed C57BL\/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas)","volume":"54","author":"Jayaprakasam","year":"2006","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jfda.2018.06.005_bib6","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1016\/j.phymed.2014.09.005","article-title":"The protective effect of the Cornus mas fruits (cornelian cherry) on hypertriglyceridemia and atherosclerosis through PPARalpha activation in hypercholesterolemic rabbits","volume":"21","author":"Soza\u0144ski","year":"2014","journal-title":"Phytomedicine \u2013 Int J Phytother Phytopharmacol"},{"key":"10.1016\/j.jfda.2018.06.005_bib7","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1021\/jf049018+","article-title":"Insulin secretion by bioactive anthocyanins and anthocyanidins present in fruits","volume":"53","author":"Jayaprakasam","year":"2005","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jfda.2018.06.005_bib8","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.foodchem.2009.07.063","article-title":"Quali-quantitative analysis of flavonoids of Cornus mas L. (Cornaceae) fruits","volume":"119","author":"Pawlowska","year":"2010","journal-title":"Food Chem"},{"key":"10.1016\/j.jfda.2018.06.005_bib9","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jfca.2014.12.016","article-title":"Iridoids and anthocyanins in cornelian cherry (Cornus mas L.) cultivars","volume":"40","author":"Kucharska","year":"2015","journal-title":"J Food Comp Anal"},{"key":"10.1016\/j.jfda.2018.06.005_bib10","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3390\/molecules21020137","article-title":"Antiproliferative effects of new dimeric ellagitannin from Cornus alba in prostate cancer cells including apoptosis-related S-phase arrest","volume":"21","author":"Park","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.jfda.2018.06.005_bib11","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.bbapap.2008.10.012","article-title":"Evidence for pentagalloyl glucose binding to human salivary alpha-amylase through aromatic amino acid residues","volume":"1794","author":"Gyemant","year":"2009","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jfda.2018.06.005_bib12","first-page":"315","article-title":"In\u00a0vitro \u03b1-amylase and \u03b1-glucosidases inhibitory effects of some plant extracts","volume":"7","author":"Amiri","year":"2015","journal-title":"Int J Pharmacogn Phytochem Res"},{"key":"10.1016\/j.jfda.2018.06.005_bib13","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3923\/ijp.2010.18.24","article-title":"Inhibitory effect of some plant extracts on pancreatic lipase","volume":"6","author":"Gholamhoseinian","year":"2010","journal-title":"Int J Pharmacol"},{"key":"10.1016\/j.jfda.2018.06.005_bib14","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/ptr.5525","article-title":"Medicinal plants traditionally used for treatment of obesity and diabetes mellitus \u2013 screening for pancreatic lipase and \u03b1-amylase inhibition","volume":"30","author":"Buchholz","year":"2016","journal-title":"Phytother Res"},{"key":"10.1016\/j.jfda.2018.06.005_bib15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.bse.2018.05.001","article-title":"The analysis of phenolic compounds from the aerial parts of Eupatorium cannabinum L. subsp. cannabinum","volume":"79","author":"Piwowarski","year":"2018","journal-title":"Biochem Sys Ecol"},{"key":"10.1016\/j.jfda.2018.06.005_bib16","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jep.2008.08.015","article-title":"Dual inhibition of metallopeptidases ACE and NEP by extracts, and iridoids from Ligustrum vulgare L.","volume":"120","author":"Kiss","year":"2008","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.jfda.2018.06.005_bib17","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.fitote.2013.08.026","article-title":"Antioxidant and anti-inflammatory flavonol glucuronides from Polygonum aviculare L.","volume":"91","author":"Granica","year":"2013","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jfda.2018.06.005_bib18","series-title":"Klucz do oznaczania ro\u015blin naczyniowych Polski ni\u017cowej","author":"Rutkowski","year":"2011"},{"key":"10.1016\/j.jfda.2018.06.005_bib19","series-title":"W\u0142a\u015bciwo\u015bci antyoksydacyjne owoc\u00f3w ba\u017cyny czarnojagodowej, bor\u00f3wki brusznicy, latoro\u015bli winnej, \u017curawiny b\u0142otnej a zawarto\u015b\u0107 zwi\u0105zk\u00f3w polifenolowych i witaminy C","author":"Markiewicz","year":"2000"},{"key":"10.1016\/j.jfda.2018.06.005_bib20","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0076-6879(99)99017-1","article-title":"Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent","volume":"299","author":"Singleton","year":"1999","journal-title":"Meth Enzymol"},{"key":"10.1016\/j.jfda.2018.06.005_bib21","doi-asserted-by":"crossref","first-page":"3251","DOI":"10.5012\/bkcs.2011.32.9.3251","article-title":"Three new iridoid glucosides from the roots Patrinia scabra","volume":"32","author":"Di","year":"2011","journal-title":"Bull Korean Chem Soc"},{"key":"10.1016\/j.jfda.2018.06.005_bib22","doi-asserted-by":"crossref","first-page":"2975","DOI":"10.1016\/0031-9422(90)87118-E","article-title":"A galloylated monoterpene glucoside and a dimeric hydrolysable tannin from Cornus officinalis","volume":"29","author":"Hatano","year":"1990","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jfda.2018.06.005_bib23","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0031-9422(00)81521-6","article-title":"Phenolic glucosides from Prunus grayana","volume":"26","author":"Shimomura","year":"1987","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jfda.2018.06.005_bib24","first-page":"710972","article-title":"UPLC-TOF-MS characterization and identification of bioactive iridoids in Cornus mas fruit","volume":"2013","author":"Deng","year":"2013","journal-title":"J\u00a0Anal Methods Chem"},{"key":"10.1016\/j.jfda.2018.06.005_bib25","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1111\/j.1365-2621.2012.02985.x","article-title":"Antioxidant, toxicity, and iridoids tests of processed Cornelian cherry fruits","volume":"47","author":"West","year":"2012","journal-title":"Int J Food Sci Technol"},{"key":"10.1016\/j.jfda.2018.06.005_bib26","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1021\/jf0115903","article-title":"Characterization, quantification, and bioactivities of anthocyanins in Cornus species","volume":"50","author":"Seeram","year":"2002","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jfda.2018.06.005_bib27","series-title":"Zwi\u0105zki aktywne owoc\u00f3w derenia (Cornus mas L","author":"Kucharska","year":"2012"},{"key":"10.1016\/j.jfda.2018.06.005_bib28","first-page":"358","article-title":"Total phenolics, flavonoid content and antioxidant power of leaf, flower and fruits from cornelian cherry (Cornus mas L.)","volume":"20","author":"Stankovic","year":"2014","journal-title":"Bulg J Agric Sci"},{"key":"10.1016\/j.jfda.2018.06.005_bib29","doi-asserted-by":"crossref","first-page":"8177","DOI":"10.3390\/molecules19068177","article-title":"Influence of temperature and preserving agents on the stability of cornelian cherries anthocyanins","volume":"19","author":"Moldovan","year":"2014","journal-title":"Molecules"},{"key":"10.1016\/j.jfda.2018.06.005_bib30","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1365-2621.2002.tb10631.x","article-title":"Degradation kinetics of anthocyanins from sour cherry, pomegranate, and strawberry juices by hydrogen peroxide","volume":"67","author":"\u00d6zkan","year":"2002","journal-title":"J Food Sci"},{"key":"10.1016\/j.jfda.2018.06.005_bib31","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.foodchem.2003.08.011","article-title":"Stability of anthocyanin-based aqueous extracts of Andean purple corn and red-fleshed sweet potato compared to synthetic and natural colorants","volume":"86","author":"Cevallos-Casalas","year":"2004","journal-title":"Food Chem"},{"key":"10.1016\/j.jfda.2018.06.005_bib32","doi-asserted-by":"crossref","first-page":"11655","DOI":"10.3390\/molecules171011655","article-title":"Degradation kinetics of anthocyanins from European cranberrybush (Viburnum opulus L.) fruit extracts. Effects of temperature, pH and storage solvent","volume":"17","author":"Moldovan","year":"2012","journal-title":"Molecules"},{"key":"10.1016\/j.jfda.2018.06.005_bib33","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1089\/jmf.2006.234","article-title":"Health benefits of traditional corn, beans, and pumpkin: in\u00a0vitro studies for hyperglycemia and hypertension management","volume":"10","author":"Kwon","year":"2007","journal-title":"J Med Food"},{"key":"10.1016\/j.jfda.2018.06.005_bib34","doi-asserted-by":"crossref","first-page":"2797","DOI":"10.1016\/j.lfs.2005.11.012","article-title":"Effects of Arachis hypogaea nutshell extract on lipid metabolic enzymes and obesity parameters","volume":"78","author":"Moreno","year":"2006","journal-title":"Life Sci"},{"key":"10.1016\/j.jfda.2018.06.005_bib35","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/sj.ijo.0802245","article-title":"Inhibitory effect of the pancreatic lipase C-terminal domain on intestinal lipolysis in rats fed a high-fat diet: chronic study","volume":"27","author":"Sebban-Kreuzer","year":"2003","journal-title":"Int J Obes Relat Metab Disord \u2013 J Int Assoc Study Obesity"},{"key":"10.1016\/j.jfda.2018.06.005_bib36","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.jff.2017.04.005","article-title":"Digestive enzyme inhibition activity of the phenolic substances in selected fruits, vegetables and tea as compared to black legumes","volume":"38","author":"Tan","year":"2017","journal-title":"J Func Foods"},{"key":"10.1016\/j.jfda.2018.06.005_bib37","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jfda.2017.03.001","article-title":"The effects of Ficus carica on the activity of enzymes related to metabolic syndrome","volume":"26","author":"Mopuri","year":"2018","journal-title":"J Food Drug Anal"},{"key":"10.1016\/j.jfda.2018.06.005_bib38","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1089\/jmf.2006.147","article-title":"Anti-obesity and hypolipidemic effects of black soybean anthocyanins","volume":"10","author":"Kwon","year":"2007","journal-title":"J Med Food"},{"key":"10.1016\/j.jfda.2018.06.005_bib39","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1358\/mf.2007.29.2.1075349","article-title":"Hypoglycemic and hypolipidemic effects of Aronia melanocarpa fruit juice in streptozotocin-induced diabetic rats","volume":"29","author":"Valcheva-Kuzmanova","year":"2007","journal-title":"Methods Find Exp Clin Pharmacol"},{"key":"10.1016\/j.jfda.2018.06.005_bib40","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1007\/s11130-008-0087-7","article-title":"Ingestion of black chokeberry fruit extract leads to intestinal and systemic changes in a rat model of prediabetes and hyperlipidemia","volume":"63","author":"Jurgo\u0144ski","year":"2008","journal-title":"Plant Foods Hum Nutr"},{"key":"10.1016\/j.jfda.2018.06.005_bib41","series-title":"Anthocyanins and human health: biomolecular and therapeutic aspects","author":"Haq","year":"2016"},{"key":"10.1016\/j.jfda.2018.06.005_bib42","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.jfda.2016.03.003","article-title":"Influence of gallic acid on alpha-amylase and alpha-glucosidase inhibitory properties of acarbose","volume":"24","author":"Oboh","year":"2016","journal-title":"J Food Drug Anal"}],"container-title":["Journal of Food and Drug Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1021949818301108?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1021949818301108?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1021949818301108?httpAccept=text\/plain","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T18:19:31Z","timestamp":1666635571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1021949818301108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S1021949818301108"],"URL":"https:\/\/doi.org\/10.1016\/j.jfda.2018.06.005","relation":{},"ISSN":["1021-9498"],"issn-type":[{"value":"1021-9498","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In\u00a0vitro \u03b1-amylase and pancreatic lipase inhibitory activity of Cornus mas L. and Cornus alba L. fruit extracts","name":"articletitle","label":"Article Title"},{"value":"Journal of Food and Drug Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jfda.2018.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Food and Drug Administration, Taiwan. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}