{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:19:23Z","timestamp":1761718763006,"version":"build-2065373602"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Forensic and Legal Medicine"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.jflm.2018.07.001","type":"journal-article","created":{"date-parts":[[2018,7,7]],"date-time":"2018-07-07T15:57:57Z","timestamp":1530979077000},"page":"179-182","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Aortic dissection in cocaine abuse: A fatal case"],"prefix":"10.1016","volume":"58","author":[{"given":"S.","family":"D'Errico","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Niballi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Bonuccelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jflm.2018.07.001_bib1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/jat\/24.7.467","article-title":"ELimination of cocaine and metabolites in plasma, saliva and urine following repeated oral admnistration to human volunteers","volume":"24","author":"Jufer","year":"2000","journal-title":"J Anal Toxicol"},{"issue":"14","key":"10.1016\/j.jflm.2018.07.001_bib2","first-page":"1131","article-title":"Cocaine related acute aortic dissection: patient demographics and clinical outcomes","volume":"23","author":"Singh","year":"2007","journal-title":"Can J Cardiol"},{"issue":"11","key":"10.1016\/j.jflm.2018.07.001_bib3","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1016\/j.amjmed.2015.01.043","article-title":"Cocaine related aortic dissection: questions yet to be resolved","volume":"128","author":"Lucyk","year":"2015","journal-title":"Am J Med"},{"issue":"3","key":"10.1016\/j.jflm.2018.07.001_bib4","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1016\/j.jemermed.2015.02.006","article-title":"Cocaine-induced acute aortic dissection","volume":"49","author":"Shah","year":"2015","journal-title":"J Emerg Med"},{"issue":"10","key":"10.1016\/j.jflm.2018.07.001_bib5","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.amjmed.2013.04.020","article-title":"International Registry of cute aortic dissection (IRAD) Investigators. Acute aortic dissection in blacks: insights from the International Registry of acute Aortic Dissection","volume":"126","author":"Bosseone","year":"2013","journal-title":"Am J Med"},{"issue":"4","key":"10.1016\/j.jflm.2018.07.001_bib6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s004140050066","article-title":"Myocardial necrosis and cocaine. A quantitative morphologic study in 26 cocaine-associated deaths","volume":"110","author":"Fineschi","year":"1997","journal-title":"Int J Leg Med"},{"key":"10.1016\/j.jflm.2018.07.001_bib7","doi-asserted-by":"crossref","first-page":"44262","DOI":"10.1038\/srep44262","article-title":"Myocardial oxidative damage is induced by cardiac Fas-dependent and mitochondria-dependent apoptotic pathways in human cocaine-related overdose","volume":"7","author":"Turillazzi","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jflm.2018.07.001_bib8","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0014-2999(80)90113-2","article-title":"The effects of cocaine, chlorpheniramine and tripelennamine on the cardiac responses to sympathetic nerve stimulation","volume":"63","author":"Matsuda","year":"1980","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.jflm.2018.07.001_bib9","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0031-6997(25)06843-7","article-title":"Presynaptic regulation of the release of cathecolamines","volume":"32","author":"Langer","year":"1980","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.jflm.2018.07.001_bib10","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.jacc.2007.03.060","article-title":"Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans","volume":"50","author":"Menon","year":"2007","journal-title":"J Am Coll Cardiol"},{"issue":"33","key":"10.1016\/j.jflm.2018.07.001_bib11","doi-asserted-by":"crossref","first-page":"5619","DOI":"10.2174\/092986712803988785","article-title":"Role of oxidative stress in cocaine-induced cardiotoxicity and cocaine related death","volume":"19","author":"Cerretani","year":"2012","journal-title":"Curr Med Chem"},{"issue":"10","key":"10.1016\/j.jflm.2018.07.001_bib12","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/j.1751-7176.2011.00520.x","article-title":"Hemodynamic and arrhythmogenic effects of cocaine in hypertensive individuals","volume":"13","author":"Secemsky","year":"2011","journal-title":"J Clin Hypertens"},{"issue":"1","key":"10.1016\/j.jflm.2018.07.001_bib13","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jacc.2017.05.014","article-title":"The cardiovascular effects of cocaine","volume":"70","author":"Havakuk","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.jflm.2018.07.001_bib14","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.tcm.2014.12.013","article-title":"Cardiovascular consequences of cocaine use","volume":"25","author":"Stankowsky","year":"2015","journal-title":"Trends Cardiovasc Med"},{"issue":"959","key":"10.1016\/j.jflm.2018.07.001_bib15","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1136\/pgmj.2004.028571","article-title":"Cocaine and the heart","volume":"81","author":"Egred","year":"2005","journal-title":"Postgrad Med J"},{"issue":"6","key":"10.1016\/j.jflm.2018.07.001_bib16","first-page":"302","article-title":"Cardiovascular complications associated with cocaine use","volume":"156","author":"Velasquez","year":"2004","journal-title":"J La State Med Soc"},{"doi-asserted-by":"crossref","unstructured":"Singh A., Khaja A., Alpert AA. Cocaine and aortic dissection. Vasc Med. 15(2):127\u2013133.","key":"10.1016\/j.jflm.2018.07.001_bib17","DOI":"10.1177\/1358863X09358749"},{"key":"10.1016\/j.jflm.2018.07.001_bib18","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.jvs.2007.05.040","article-title":"Acute aortic dissection associated with use of cocaine","volume":"46","author":"Danile","year":"2007","journal-title":"J Vasc Surg"},{"issue":"1","key":"10.1016\/j.jflm.2018.07.001_bib19","first-page":"e2059","article-title":"Cocaine-induced type A aortic dissection extending to the common iliac arteries","volume":"10","author":"Mohamed","year":"2018","journal-title":"Cureus"},{"key":"10.1016\/j.jflm.2018.07.001_bib20","article-title":"Rare case of cocaine-induced aortic aneurysm: a near dissection event","volume":"2017","author":"Kunvor","year":"2017","journal-title":"Case Rep Cardiol"},{"key":"10.1016\/j.jflm.2018.07.001_bib21","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2016-218235","article-title":"Chronic hypertension, recreational cocaine use and a subsequent acute aortic dissection in a young adult","volume":"2017","author":"Dewar","year":"2017","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.jflm.2018.07.001_bib22","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1161\/01.CIR.105.13.1529","article-title":"International Registry for aortic dissection (IRAD) investigators. Cocaine related aortic dissection in perspective","volume":"105","author":"Eagle","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jflm.2018.07.001_bib23","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1161\/01.CIR.0000012524.44897.3A","article-title":"Acute aortic dissection related to crack cocaine","volume":"105","author":"Hsue","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jflm.2018.07.001_bib24","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0735-6757(97)90196-0","article-title":"Thoracic aortic dissection secondary to crack cocaine ingestion","volume":"15","author":"Perron","year":"1997","journal-title":"Am J Emerg Med"},{"issue":"12","key":"10.1016\/j.jflm.2018.07.001_bib25","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1007\/s00392-011-0363-7","article-title":"Aortic dissection after cocaine abuse","volume":"100","author":"Correale","year":"2011","journal-title":"Clin Res Cardiol"},{"issue":"7","key":"10.1016\/j.jflm.2018.07.001_bib26","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.jflm.2011.06.008","article-title":"Aortic dissection and cocaine use","volume":"18","author":"Marella","year":"2011","journal-title":"J Forensic Leg Med"},{"issue":"6","key":"10.1016\/j.jflm.2018.07.001_bib27","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s004140000194","article-title":"Markers of cardiac oxidative stress and altered morphology after intraperitoneal cocaine injection in a rat model","volume":"114","author":"Fineschi","year":"2001","journal-title":"Int J Leg Med"},{"key":"10.1016\/j.jflm.2018.07.001_bib28","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1056\/NEJM200108023450508","article-title":"Of nicks and time","volume":"345","author":"Nallamothu","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jflm.2018.07.001_bib29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/j.1875-9114.1990.tb02550.x","article-title":"Cocaine abuse and its treatment","volume":"10","author":"Hall","year":"1990","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.jflm.2018.07.001_bib30","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1161\/01.CIR.0000012524.44897.3A","article-title":"Acute aortic dissection related to crack cocaine","volume":"105","author":"Hsue","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jflm.2018.07.001_bib31","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1080\/10915810490471361","article-title":"Cocaine induces apoptosis in primary cultured rat aortic vascular smooth muscle cells: possible relationship to aortic dissection, atherosclerosis, and hypertension","volume":"23","author":"Su","year":"2004","journal-title":"Int J Toxicol"},{"key":"10.1016\/j.jflm.2018.07.001_bib32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S1054-8807(01)00074-6","article-title":"Spontaneous coronary artery dissection associated with cocaine use: a case report and brief review","volume":"10","author":"Steinhauer","year":"2001","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.jflm.2018.07.001_bib33","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.mehy.2011.04.011","article-title":"Cocaine mediated apoptosis of vascular cells as a mechanism for carotid artery dissection leading to ischemic stroke","volume":"77","author":"Dabbouseh","year":"2011","journal-title":"Med Hypotheses"},{"issue":"7","key":"10.1016\/j.jflm.2018.07.001_bib34","first-page":"448","article-title":"Carotid dissection in a cocaine-abusing patient","volume":"46","author":"Oelker-Behn","year":"2008","journal-title":"Rev Neurol"},{"key":"10.1016\/j.jflm.2018.07.001_bib35","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1540-8175.2007.00593.x","article-title":"Effect of chronic cocaine abuse on the elastic properties of aorta","volume":"25","author":"Bigi","year":"2008","journal-title":"Echocardiography"},{"key":"10.1016\/j.jflm.2018.07.001_bib36","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1006\/clim.1998.4683","article-title":"Cocaine enhances brain endothelial adhesion molecules and leukocytes migration","volume":"91","author":"Gan","year":"2001","journal-title":"Clin Immunol"},{"issue":"5","key":"10.1016\/j.jflm.2018.07.001_bib37","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/clc.20746","article-title":"Cocaine and the heart","volume":"33","author":"Maraj","year":"2010","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.jflm.2018.07.001_bib38","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1186\/1757-1626-1-369","article-title":"A case of aortic dissection in a cocaine abuser: a case report and review of literature","volume":"1","author":"Nusair","year":"2008","journal-title":"Cases J"},{"key":"10.1016\/j.jflm.2018.07.001_bib39","doi-asserted-by":"crossref","first-page":"174132","DOI":"10.1155\/2011\/174132","article-title":"Dexmedetomidine use in the setting of cocaine-induced hypertensive emergency and aortic dissection: a novel indication","volume":"2011","author":"Javed","year":"2011","journal-title":"Case Rep Med"},{"key":"10.1016\/j.jflm.2018.07.001_bib40","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/0002-8703(92)90676-M","article-title":"Transesophageal echocardiographic diagnosis of acute aortic dissection complicating cocaine abuse","volume":"123","author":"Om","year":"1992","journal-title":"Am Heart J"},{"key":"10.1016\/j.jflm.2018.07.001_bib41","first-page":"723","article-title":"Dissection of the aorta and coronary arteries with acute cocaine intoxication","volume":"10","author":"Cohle","year":"1992","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.jflm.2018.07.001_bib42","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/0002-8703(92)90676-M","article-title":"Transesophageal echocardiographic diagnosis of acute aortic dissection complicating cocaine abuse","volume":"123","author":"Om","year":"1992","journal-title":"Am Heart J"},{"key":"10.1016\/j.jflm.2018.07.001_bib43","first-page":"723","article-title":"Dissection of the aorta and coronary arteries with acute cocaine intoxication","volume":"10","author":"Cohle","year":"1992","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.jflm.2018.07.001_bib44","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/0002-9149(86)90787-3","article-title":"Rupture of the ascending aorta during cocaine intoxication","volume":"57","author":"Barth","year":"1986","journal-title":"Am J Cardiol"}],"container-title":["Journal of Forensic and Legal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1752928X1830310X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1752928X1830310X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:13:29Z","timestamp":1761696809000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1752928X1830310X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":44,"alternative-id":["S1752928X1830310X"],"URL":"https:\/\/doi.org\/10.1016\/j.jflm.2018.07.001","relation":{},"ISSN":["1752-928X"],"issn-type":[{"type":"print","value":"1752-928X"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aortic dissection in cocaine abuse: A fatal case","name":"articletitle","label":"Article Title"},{"value":"Journal of Forensic and Legal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jflm.2018.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.","name":"copyright","label":"Copyright"}]}}