{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T15:26:17Z","timestamp":1789572377009,"version":"build-2803163510"},"reference-count":124,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Forensic and Legal Medicine"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.jflm.2023.102599","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T06:34:05Z","timestamp":1696833245000},"page":"102599","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Postmortem biochemistry in deaths from ischemic heart disease"],"prefix":"10.1016","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9359-4247","authenticated-orcid":false,"given":"Erdi","family":"Kutlu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esin","family":"Avci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kemalettin","family":"Acar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/20961790.2019.1622062","article-title":"Sudden cardiac death","volume":"4","author":"Lucena","year":"2019","journal-title":"Forensic Sci Res"},{"issue":"14","key":"10.1016\/j.jflm.2023.102599_bib2","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1016\/j.jacc.2017.10.054","article-title":"AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American college of cardiology\/American heart association Task Force on clinical practice guidelines and the hea","volume":"72","author":"Al-Khatib","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jflm.2023.102599_bib3","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.hlc.2018.08.026","article-title":"Epidemiology of sudden cardiac death: global and regional perspectives","volume":"28","author":"Wong","year":"2019","journal-title":"Heart Lung Circ"},{"issue":"6","key":"10.1016\/j.jflm.2023.102599_bib4","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s00428-017-2221-0","article-title":"Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology","volume":"471","author":"Basso","year":"2017","journal-title":"Virchows Arch"},{"key":"10.1016\/j.jflm.2023.102599_bib5","series-title":"International Statistical Classification of Diseases and Related Health Problems","year":"2015"},{"key":"10.1016\/j.jflm.2023.102599_bib6","article-title":"WHO scientific group on sudden cardiac death & world health organization","author":"Organization","year":"1985","journal-title":"Sudden cardiac death : report of a WHO scientific group"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib7","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/nrcardio.2010.3","article-title":"Sudden cardiac death: epidemiology and risk factors","volume":"7","author":"Adabag","year":"2010","journal-title":"Nat Rev Cardiol"},{"issue":"22","key":"10.1016\/j.jflm.2023.102599_bib8","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1161\/CIRCULATIONAHA.110.976092","article-title":"Sudden cardiac death prediction and prevention report from a national heart, lung, and blood institute and heart rhythm society workshop","volume":"122","author":"Fishman","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jflm.2023.102599_bib9","first-page":"1601","article-title":"ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death","volume":"17","author":"Priori","year":"2015","journal-title":"Ep Eur"},{"key":"10.1016\/j.jflm.2023.102599_bib10","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1007\/s00414-019-02225-8","article-title":"Second opinion system for sudden cardiac death cases in forensic practice","volume":"134","author":"Sabatasso","year":"2020","journal-title":"Int J Leg Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib11","doi-asserted-by":"crossref","first-page":"147","DOI":"10.31083\/j.rcm.2021.01.207","article-title":"Sudden cardiac death: epidemiology, pathogenesis and management","volume":"22","author":"Kumar","year":"2021","journal-title":"Rev Cardiovasc Med"},{"key":"10.1016\/j.jflm.2023.102599_bib12","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00414-013-0819-6","article-title":"Postmortem imaging of sudden cardiac death","volume":"128","author":"Michaud","year":"2014","journal-title":"Int J Leg Med"},{"key":"10.1016\/j.jflm.2023.102599_bib13","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/imj.14359","article-title":"Sudden cardiac death: an update","volume":"49","author":"Isbister","year":"2019","journal-title":"Intern Med J"},{"key":"10.1016\/j.jflm.2023.102599_bib14","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s00414-014-0966-4","article-title":"Negative autopsy and sudden cardiac death","volume":"128","author":"Campuzano","year":"2014","journal-title":"Int J Leg Med"},{"key":"10.1016\/j.jflm.2023.102599_bib15","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s00414-020-02481-z","article-title":"Sudden cardiac death-update","volume":"135","author":"Markwerth","year":"2021","journal-title":"Int J Leg Med"},{"key":"10.1016\/j.jflm.2023.102599_bib16","first-page":"1","article-title":"ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation","volume":"2020","author":"Collet","year":"2020","journal-title":"Eur Heart J"},{"issue":"10065","key":"10.1016\/j.jflm.2023.102599_bib17","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0140-6736(16)30677-8","article-title":"Acute myocardial infarction","volume":"389","author":"Reed","year":"2017","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib18","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/eurheartj\/ehy462","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"40","author":"Thygesen","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jflm.2023.102599_bib19","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s00414-016-1494-1","article-title":"Immunohistochemical detection of early myocardial infarction: a systematic review","volume":"131","author":"Mondello","year":"2017","journal-title":"Int J Leg Med"},{"issue":"5","key":"10.1016\/j.jflm.2023.102599_bib20","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1007\/s00414-016-1401-9","article-title":"Early markers for myocardial ischemia and sudden cardiac death","volume":"130","author":"Sabatasso","year":"2016","journal-title":"Int J Leg Med"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib21","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.legalmed.2010.12.005","article-title":"Forensic biochemistry for functional investigation of death: concept and practical application","volume":"13","author":"Maeda","year":"2011","journal-title":"Leg Med"},{"key":"10.1016\/j.jflm.2023.102599_bib22","doi-asserted-by":"crossref","first-page":"S46","DOI":"10.1016\/j.legalmed.2009.01.048","article-title":"Significance of postmortem biochemistry in determining the cause of death","volume":"11","author":"Maeda","year":"2009","journal-title":"Leg Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib23","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.legalmed.2011.10.004","article-title":"Usefulness of postmortem biochemistry in forensic pathology: illustrative case reports","volume":"14","author":"Palmiere","year":"2012","journal-title":"Leg Med"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib24","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1067\/mcp.2001.113989","article-title":"Biomarkers and surrogate endpoints: preferred definitions and conceptual framework","volume":"69","author":"Atkinson","year":"2001","journal-title":"Clin Pharmacol Ther"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cll.2013.11.005","article-title":"Overview of cardiac markers in heart disease","volume":"34","author":"Jarolim","year":"2014","journal-title":"Clin Lab Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib26","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/10408363.2018.1525335","article-title":"Novel biomarkers of cardiovascular disease: applications in clinical practice","volume":"56","author":"Lyngbakken","year":"2019","journal-title":"Crit Rev Clin Lab Sci"},{"issue":"10","key":"10.1016\/j.jflm.2023.102599_bib27","doi-asserted-by":"crossref","DOI":"10.21037\/atm.2016.05.19","article-title":"An historical approach to the diagnostic biomarkers of acute coronary syndrome","volume":"4","author":"Danese","year":"2016","journal-title":"Ann Transl Med"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib28","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.ahj.2010.06.010","article-title":"Novel biomarkers in cardiovascular disease: update 2010","volume":"160","author":"Hochholzer","year":"2010","journal-title":"Am Heart J"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib29","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s11739-017-1612-1","article-title":"Cardiac biomarkers of acute coronary syndrome: from history to high-sensitivity cardiac troponin","volume":"12","author":"Garg","year":"2017","journal-title":"Intern Emerg Med"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib30","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jacc.2010.03.037","article-title":"Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications","volume":"56","author":"Shave","year":"2010","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.jflm.2023.102599_bib31","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s40291-012-0011-6","article-title":"Cardiac troponins i and T: molecular markers for early diagnosis, prognosis, and accurate triaging of patients with acute myocardial infarction","volume":"16","author":"Tiwari","year":"2012","journal-title":"Mol Diagn Ther"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib32","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1161\/01.CIR.88.2.750","article-title":"Biochemical markers of myocardial injury is MB creatine kinase the choice for the 1990s?","volume":"88","author":"Adams","year":"1993","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.jflm.2023.102599_bib33","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1093\/eurheartj\/eht530","article-title":"Biomarkers and acute coronary syndromes: an update","volume":"35","author":"Mueller","year":"2014","journal-title":"Eur Heart J"},{"issue":"5","key":"10.1016\/j.jflm.2023.102599_bib34","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1111\/1556-4029.13397","article-title":"Use of cardiac injury markers in the postmortem diagnosis of sudden cardiac death","volume":"62","author":"Carvajal-Zarrabal","year":"2017","journal-title":"J Forensic Sci"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib35","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/PAF.0b013e3182880aa1","article-title":"Diagnostic value of cardiac troponin i in postmortem diagnosis of myocardial infarction","volume":"34","author":"Sapouna","year":"2013","journal-title":"Am J Forensic Med Pathol"},{"issue":"1-3","key":"10.1016\/j.jflm.2023.102599_bib36","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.forsciint.2013.09.010","article-title":"Cardiac troponin T in forensic autopsy cases","volume":"233","author":"Remmer","year":"2013","journal-title":"Forensic Sci Int"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib37","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1111\/j.1556-4029.2010.01368.x","article-title":"The role of postmortem cardiac markers in the diagnosis of acute myocardial infarction","volume":"55","author":"Batalis","year":"2010","journal-title":"J Forensic Sci"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.forsciint.2004.02.007","article-title":"Diagnostic efficacy of biochemical markers in diagnosis post-mortem of ischaemic heart disease","volume":"142","author":"P\u00e9rez-C\u00e1rceles","year":"2004","journal-title":"Forensic Sci Int"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib39","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s004140050143","article-title":"Cardiac troponin I (cTn I) and the postmortem diagnosis of myocardial infarction","volume":"111","author":"Osuna","year":"1998","journal-title":"Int J Leg Med"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib40","first-page":"143","article-title":"Post mortem troponin T analysis in sudden death: is it useful?","volume":"40","author":"Rahimi","year":"2018","journal-title":"Malays J Pathol"},{"issue":"5","key":"10.1016\/j.jflm.2023.102599_bib41","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.legalmed.2015.03.007","article-title":"Cardiac biomarkers in blood, and pericardial and cerebrospinal fluids of forensic autopsy cases: a reassessment with special regard to postmortem interval","volume":"17","author":"Chen","year":"2015","journal-title":"Leg Med"},{"issue":"5","key":"10.1016\/j.jflm.2023.102599_bib42","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.legalmed.2011.05.002","article-title":"Combined analyses of creatine kinase MB, cardiac troponin I and myoglobin in pericardial and cerebrospinal fluids to investigate myocardial and skeletal muscle injury in medicolegal autopsy cases","volume":"13","author":"Wang","year":"2011","journal-title":"Leg Med"},{"issue":"5","key":"10.1016\/j.jflm.2023.102599_bib43","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.legalmed.2007.01.010","article-title":"Postmortem cardiac troponin I and creatine kinase MB levels in the blood and pericardial fluid as markers of myocardial damage in medicolegal autopsy","volume":"9","author":"Zhu","year":"2007","journal-title":"Leg Med"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib44","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/00000433-199912000-00004","article-title":"A study of various morphologic variables and troponin I in pericardial fluid as possible discriminators of sudden cardiac death","volume":"20","author":"Cs","year":"1999","journal-title":"Am J Forensic Med Pathol"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib45","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/PAF.0000000000000662","article-title":"Autopsy cardiac troponin i plasma levels can Be elevated in myocardial infarction type 3: a proposal to modify the definition of myocardial infarction type 3","volume":"42","author":"Omalu","year":"2021","journal-title":"Am J Forensic Med Pathol"},{"key":"10.1016\/j.jflm.2023.102599_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2022.111506","article-title":"Cardiac troponin T as a postmortem biomarker for acute myocardial infarction","volume":"341","author":"Moridi","year":"2022","journal-title":"Forensic Sci Int"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib47","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s12024-016-9749-1","article-title":"Cardiac troponin T determination by a highly sensitive assay in postmortem serum and pericardial fluid","volume":"12","author":"Gonz\u00e1lez-Herrera","year":"2016","journal-title":"Forensic Sci Med Pathol"},{"key":"10.1016\/j.jflm.2023.102599_bib48","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.forsciint.2018.05.051","article-title":"High-sensitive cardiac troponin hs-TnT levels in sudden deaths related to atherosclerotic coronary artery disease","volume":"289","author":"Beausire","year":"2018","journal-title":"Forensic Sci Int"},{"issue":"January","key":"10.1016\/j.jflm.2023.102599_bib49","article-title":"Significance of postmortem biomarkers and multimarker strategy in sudden cardiac death","volume":"61","author":"Kutlu","year":"2023","journal-title":"Leg Med"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib50","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s11547-016-0698-2","article-title":"Diagnosis of myocardial ischemia combining multiphase postmortem CT-angiography, histology, and postmortem biochemistry","volume":"122","author":"Vanhaebost","year":"2017","journal-title":"Radiol Medica"},{"key":"10.1016\/j.jflm.2023.102599_bib51","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.forsciint.2017.11.034","article-title":"Cardiac troponins and NT-proBNP in the forensic setting: overview of sampling site, postmortem interval, cardiopulmonary resuscitation, and review of the literature","volume":"282","author":"Palmiere","year":"2018","journal-title":"Forensic Sci Int"},{"key":"10.1016\/j.jflm.2023.102599_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.jflm.2021.102127","article-title":"Diagnostic value of high-sensitivity troponin T in postmortem diagnosis of sudden cardiac death","volume":"78","author":"Zribi","year":"2021","journal-title":"J Forensic Leg Med"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib53","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/s12024-019-00150-1","article-title":"Combined determination of B-type natriuretic peptide and high-sensitivity troponin I in the postmortem diagnosis of cardiac disease","volume":"15","author":"Ba\u00f1\u00f3n","year":"2019","journal-title":"Forensic Sci Med Pathol"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/diagnostics11040614","article-title":"Diagnostic application of postmortem cardiac troponin i pericardial fluid\/serum ratio in sudden cardiac death","volume":"11","author":"Hern\u00e1ndez-Romero","year":"2021","journal-title":"Diagnostics"},{"key":"10.1016\/j.jflm.2023.102599_bib55","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.forsciint.2018.09.002","article-title":"The use of cardiac troponin T (cTnT) in the postmortem diagnosis of acute myocardial infarction and sudden cardiac death: a systematic review","volume":"292","author":"Barberi","year":"2018","journal-title":"Forensic Sci Int"},{"issue":"13","key":"10.1016\/j.jflm.2023.102599_bib56","doi-asserted-by":"crossref","first-page":"3351","DOI":"10.3390\/ijms20133351","article-title":"Diagnostic roles of postmortem cTn I and cTn T in cardiac death with special regard to myocardial infarction: a systematic literature review and meta-analysis","volume":"20","author":"Cao","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/10409230590918577","article-title":"Relating structure to mechanism in creatine kinase","volume":"40","author":"McLeish","year":"2005","journal-title":"Crit Rev Biochem Mol Biol"},{"key":"10.1016\/j.jflm.2023.102599_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2147\/VHRM.S166157","article-title":"Biomarkers in acute myocardial infarction: current perspectives","volume":"15","author":"Aydin","year":"2019","journal-title":"Vasc Health Risk Manag"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib59","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408369709038215","article-title":"Progress in myocardial damage detection: new biochemical markers for clinicians","volume":"34","author":"Mair","year":"1997","journal-title":"Crit Rev Clin Lab Sci"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib60","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0379-0738(83)90116-0","article-title":"The postmortem determination of CK isozymes in the pericardial fluid in various causes of death","volume":"22","author":"Luna","year":"1983","journal-title":"Forensic Sci Int"},{"key":"10.1016\/j.jflm.2023.102599_bib61","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jflm.2014.09.011","article-title":"Distribution & diagnostic efficacy of cardiac markers CK-MB & LDH in pericardial fluid for postmortem diagnosis of ischemic heart disease","volume":"28","author":"Ghormade","year":"2014","journal-title":"J Forensic Leg Med"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib62","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/00000433-199806000-00005","article-title":"Distribution of biochemical markers in biologic fluids: application to the postmortem diagnosis of myocardial infarction","volume":"19","author":"Osuna","year":"1998","journal-title":"Am J Forensic Med Pathol"},{"key":"10.1016\/j.jflm.2023.102599_bib63","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.legalmed.2009.01.005","article-title":"Analysis of cardiac troponins and creatine kinase MB in cerebrospinal fluid in medicolegal autopsy cases","volume":"11","author":"Maeda","year":"2009","journal-title":"Leg Med"},{"key":"10.1016\/j.jflm.2023.102599_bib64","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.forsciint.2004.09.011","article-title":"Sudden death: correlation histopathological and biochemical","volume":"146","author":"Mart\u00ednez-S\u00e1nchez","year":"2004","journal-title":"Forensic Sci Int"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib65","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s12024-020-00232-5","article-title":"Diagnostic role of postmortem CK-MB in cardiac death: a systematic review and meta-analysis","volume":"16","author":"Xu","year":"2020","journal-title":"Forensic Sci Med Pathol"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib66","first-page":"159","article-title":"Biochemical diagnosis of myocardial infarction","volume":"39","author":"Foreback","year":"1991","journal-title":"Henry Ford Hosp Med J"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib67","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1093\/ajcp\/97.2.217","article-title":"Acute myocardial infarction and coronary reperfusion Serum Cardiac Markers for the 1990s","volume":"97","author":"Apple","year":"1992","journal-title":"Am J Clin Pathol"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib68","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/BF01845610","article-title":"Usefulness of myosin in the postmortem diagnosis of myocardial damage","volume":"108","author":"P\u00e9rez-C\u00e1rceles","year":"1995","journal-title":"Int J Leg Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib69","first-page":"1","article-title":"Serum lactate dehydrogenase activities as systems biomarkers for 48 types of human diseases","volume":"11","author":"Wu","year":"2021","journal-title":"Sci Rep"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib70","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/ajcp\/82.4.411","article-title":"Postmortem diagnosis of myocardial disease by enzyme analysis of pericardial fluid","volume":"82","author":"Stewart","year":"1984","journal-title":"Am J Clin Pathol"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib71","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1515\/CCLM.2011.037","article-title":"Ischemia modified albumin changes - review and clinical implications","volume":"49","author":"Sbarouni","year":"2011","journal-title":"Clin Chem Lab Med"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib72","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.ijcard.2010.01.013","article-title":"Assessment of ischemia-modified albumin levels for emergency room diagnosis of acute coronary syndrome","volume":"149","author":"Shen","year":"2011","journal-title":"Int J Cardiol"},{"issue":"5","key":"10.1016\/j.jflm.2023.102599_bib73","first-page":"493","article-title":"Application of ischemia modified albumin for acute ischemic heart disease in forensic science","volume":"33","author":"Wang","year":"2017","journal-title":"Fa Yi Xue Za Zhi"},{"issue":"2","key":"10.1016\/j.jflm.2023.102599_bib74","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1080\/00450618.2017.1340519","article-title":"New postmortem diagnostic biomarker for myocardial infarction: ischemia modified albumin","volume":"51","author":"Ya\u011fmur","year":"2019","journal-title":"Aust J Forensic Sci"},{"issue":"8","key":"10.1016\/j.jflm.2023.102599_bib75","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1080\/07853890.2020.1800075","article-title":"Heart-type fatty acid-binding protein: an overlooked cardiac biomarker","volume":"52","author":"Goel","year":"2020","journal-title":"Ann Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib76","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12872-015-0026-0","article-title":"Ischemic biomarker heart-type fatty acid binding protein (hFABP) in acute heart failure - diagnostic and prognostic insights compared to NT-proBNP and troponin I","volume":"15","author":"Hoffmann","year":"2015","journal-title":"BMC Cardiovasc Disord"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib77","first-page":"BC22","article-title":"Utility of heart-type fatty acid binding protein as a new biochemical marker for the early diagnosis of acute coronary syndrome","volume":"9","author":"Gami","year":"2015","journal-title":"J Clin Diagn Res"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib78","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s12291-015-0544-7","article-title":"Heart-type fatty acid-binding protein, in early detection of acute myocardial infarction: comparison with CK-MB, troponin I and myoglobin","volume":"31","author":"Pyati","year":"2016","journal-title":"Indian J Clin Biochem"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib79","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.forsciint.2005.08.008","article-title":"Heart fatty acid binding protein as a marker for postmortem detection of early myocardial damage","volume":"160","author":"Meng","year":"2006","journal-title":"Forensic Sci Int"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib80","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3889\/oamjms.2016.018","article-title":"Role of cardiac myocytes heart fatty acid binding protein depletion (H-FABP) in early myocardial infarction in human heart (autopsy study)","volume":"4","author":"Shabaiek","year":"2016","journal-title":"Open Access Maced J Med Sci"},{"key":"10.1016\/j.jflm.2023.102599_bib81","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jflm.2016.01.015","article-title":"Heart-type fatty acid binding protein and cardiac troponin i may have a diagnostic value in electrocution: a rat model","volume":"39","author":"\u00d6zdemir","year":"2016","journal-title":"J Forensic Leg Med"},{"issue":"5","key":"10.1016\/j.jflm.2023.102599_bib82","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1056\/NEJM199807303390507","article-title":"Natriuretic peptides","volume":"339","author":"Levin","year":"1998","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib83","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1089\/met.2019.0073","article-title":"Novel invasive and noninvasive cardiac-specific biomarkers in obesity and cardiovascular diseases","volume":"18","author":"Parsanathan","year":"2020","journal-title":"Metab Syndr Relat Disord"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib84","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1741-7015-8-34","article-title":"Biomarkers in acute myocardial infarction","volume":"8","author":"Chan","year":"2010","journal-title":"BMC Med"},{"issue":"9380","key":"10.1016\/j.jflm.2023.102599_bib85","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/S0140-6736(03)13976-1","article-title":"B-type natriuretic peptide in cardiovascular disease","volume":"362","author":"De Lemos","year":"2003","journal-title":"Lancet"},{"issue":"7","key":"10.1016\/j.jflm.2023.102599_bib86","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1373\/clinchem.2010.143883","article-title":"Processing of pro\u2013B-type natriuretic peptide: furin and corin as candidate convertases","volume":"56","author":"Semenov","year":"2010","journal-title":"Clin Chem"},{"issue":"20","key":"10.1016\/j.jflm.2023.102599_bib87","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1056\/NEJMra0800239","article-title":"Biomarkers in heart failure","volume":"358","author":"Braunwald","year":"2008","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.jflm.2023.102599_bib88","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1161\/01.CIR.92.6.1558","article-title":"Rapid ventricular induction of brain natriuretic peptide gene expression in experimental acute myocardial infarction","volume":"92","author":"Hama","year":"1995","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib89","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.ejheart.2004.01.004","article-title":"Brain and other natriuretic peptides: molecular aspects","volume":"6","author":"Vanderheyden","year":"2004","journal-title":"Eur J Heart Fail"},{"issue":"8","key":"10.1016\/j.jflm.2023.102599_bib90","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.3390\/ijms20081820","article-title":"BNP and NT-proBNP as diagnostic biomarkers for cardiac dysfunction in both clinical and forensic medicine","volume":"20","author":"Cao","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jflm.2023.102599_bib91","doi-asserted-by":"crossref","unstructured":"Morita E, Yasue H, Yoshimura M, Ogawa H. Increased plasma levels of brain natriuretic peptide in patients with acute myocardial infarction. Circulation. 88(1):82-91.","DOI":"10.1161\/01.CIR.88.1.82"},{"issue":"18","key":"10.1016\/j.jflm.2023.102599_bib92","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1053\/euhj.1999.2045","article-title":"Profile of plasma N-terminal proBNP following acute myocardial infarction: correlation with left ventricular systolic dysfunction","volume":"21","author":"Talwar","year":"2000","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1016\/j.jflm.2023.102599_bib93","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.jacc.2017.04.025","article-title":"ACC\/AHA\/HFSA focused update of the 2013 ACCF\/AHA guideline for the management of heart failure: a report of the American college of cardiology\/American heart association Task Force on clinical practice guidelines and the heart failure society of amer","volume":"70","author":"Yancy","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"27","key":"10.1016\/j.jflm.2023.102599_bib94","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"37","author":"Ponikowski","year":"2016","journal-title":"Eur Heart J"},{"issue":"8","key":"10.1016\/j.jflm.2023.102599_bib95","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.amjmed.2011.02.035","article-title":"N-terminal pro B-type natriuretic peptide in the early evaluation of suspected acute myocardial infarction","volume":"124","author":"Haaf","year":"2011","journal-title":"Am J Med"},{"issue":"11","key":"10.1016\/j.jflm.2023.102599_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjmed.2005.05.020","article-title":"Use of N-terminal pro-B-type natriuretic peptide to detect myocardial ischemia","volume":"118","author":"Staub","year":"2005","journal-title":"Am J Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib97","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1007\/s00414-006-0102-1","article-title":"Postmortem pericardial natriuretic peptides as markers of cardiac function in medico-legal autopsies","volume":"121","author":"Zhu","year":"2007","journal-title":"Int J Leg Med"},{"key":"10.1016\/j.jflm.2023.102599_bib98","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1007\/s00414-012-0732-4","article-title":"Molecular pathology of natriuretic peptides in the myocardium with special regard to fatal intoxication , hypothermia , and hyperthermia","volume":"126","author":"Chen","year":"2012","journal-title":"Int J Leg Med"},{"issue":"1-3","key":"10.1016\/j.jflm.2023.102599_bib99","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.forsciint.2012.10.018","article-title":"Pathophysiology of sudden cardiac death as demonstrated by molecular pathology of natriuretic peptides in the myocardium","volume":"223","author":"Chen","year":"2012","journal-title":"Forensic Sci Int"},{"issue":"5","key":"10.1016\/j.jflm.2023.102599_bib100","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s00414-008-0257-z","article-title":"Evaluation of postmortem measurement of NT-proBNP as a marker for cardiac function","volume":"122","author":"Michaud","year":"2008","journal-title":"Int J Leg Med"},{"issue":"6","key":"10.1016\/j.jflm.2023.102599_bib101","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/s00414-011-0581-6","article-title":"Sensitivity and specificity of NT-proBNP to detect heart failure at post mortem examination","volume":"125","author":"Sabatasso","year":"2011","journal-title":"Int J Leg Med"},{"key":"10.1016\/j.jflm.2023.102599_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2019.110079","article-title":"Postmortem urine concentration of N-terminal pro-brain natriuretic peptide in relation to the cause of death","volume":"306","author":"Takasu","year":"2020","journal-title":"Forensic Sci Int"},{"issue":"4","key":"10.1016\/j.jflm.2023.102599_bib103","doi-asserted-by":"crossref","first-page":"4763","DOI":"10.3892\/mmr.2017.7136","article-title":"Differential expression of B-type natriuretic peptide between left and right ventricles, with particular regard to sudden cardiac death","volume":"16","author":"Cao","year":"2017","journal-title":"Mol Med Rep"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib104","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1111\/1556-4029.14232","article-title":"Evaluation of agonal cardiac function for sudden cardiac death in forensic medicine with postmortem brain natriuretic peptide (BNP) and NT-proBNP: a meta-analysis","volume":"65","author":"Cao","year":"2020","journal-title":"J Forensic Sci"},{"issue":"16","key":"10.1016\/j.jflm.2023.102599_bib105","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1161\/CIRCULATIONAHA.106.685503","article-title":"C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: leicester acute myocardial infarction peptide (LAMP) study","volume":"115","author":"Khan","year":"2007","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib106","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.amjmed.2015.06.033","article-title":"Ultra-sensitive copeptin and cardiac troponin in diagnosing non-ST-segment elevation acute coronary syndromes\u2014the COPACS study","volume":"129","author":"Ricci","year":"2016","journal-title":"Am J Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib107","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1373\/clinchem.2005.060038","article-title":"Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin","volume":"52","author":"Morgenthaler","year":"2006","journal-title":"Clin Chem"},{"issue":"11","key":"10.1016\/j.jflm.2023.102599_bib108","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.3390\/jcm9113627","article-title":"Prognostic value of elevated copeptin and high-sensitivity cardiac troponin T in patients with and without acute coronary syndrome : the ConTrACS study","volume":"9","author":"Waldsperger","year":"2020","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib109","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1741-7015-10-7","article-title":"The role of copeptin as a diagnostic and prognostic biomarker for risk stratification in the emergency department","volume":"10","author":"Nickel","year":"2012","journal-title":"BMC Med"},{"key":"10.1016\/j.jflm.2023.102599_bib110","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/614145","article-title":"Copeptin testing in acute myocardial infarction : ready for routine use","volume":"2015","author":"Reinstadler","year":"2015","journal-title":"Dis Markers"},{"key":"10.1016\/j.jflm.2023.102599_bib111","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.peptides.2014.07.011","article-title":"Copeptin as a diagnostic biomarker for sepsis-related deaths","volume":"59","author":"Palmiere","year":"2014","journal-title":"Peptides"},{"issue":"6","key":"10.1016\/j.jflm.2023.102599_bib112","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.atherosclerosis.2018.10.004","article-title":"Pregnancy-associated plasma protein-A in atherosclerosis: molecular marker, mechanistic insight, and therapeutic target","volume":"278","author":"Yu","year":"2018","journal-title":"Atherosclerosis"},{"issue":"8","key":"10.1016\/j.jflm.2023.102599_bib113","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.2217\/bmm.14.53","article-title":"Pregnancy-associated plasma protein-A and the vulnerable plaque","volume":"8","author":"Jespersen","year":"2014","journal-title":"Biomarkers Med"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib114","first-page":"BC01","article-title":"Evaluation of serum pregnancy associated plasma protein-A & Plasma D-Dimer in acute coronary syndrome","volume":"10","author":"Nichenametla","year":"2016","journal-title":"J Clin Diagn Res"},{"issue":"14","key":"10.1016\/j.jflm.2023.102599_bib115","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1056\/NEJMoa003147","article-title":"Pregnancy-associated plasma protein A as a marker of acute coronary syndromes","volume":"345","author":"Bayes-Genis","year":"2001","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.jflm.2023.102599_bib116","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s11845-016-1515-6","article-title":"Pregnancy-associated plasma protein-A (PAPP-A) as a possible biomarker in patients with coronary artery disease","volume":"186","author":"Guti\u00e9rrez-Leonard","year":"2017","journal-title":"Ir J Med Sci"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib117","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jjcc.2011.03.006","article-title":"Pentraxin 3 as a biomarker for acute coronary syndrome: comparison with biomarkers for cardiac damage","volume":"58","author":"Kume","year":"2011","journal-title":"J Cardiol"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib118","first-page":"48","article-title":"Expression of pentraxin 3 (PTX3) in human atherosclerotic lesions","volume":"215","author":"Savchenko","year":"2008","journal-title":"J Pathol A J Pathol Soc Gt Britain Irel"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib119","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1161\/01.ATV.0000252126.48375.d5","article-title":"Establishment of a high sensitivity plasma assay for human pentraxin3 as a marker for unstable angina pectoris","volume":"27","author":"Inoue","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"16","key":"10.1016\/j.jflm.2023.102599_bib120","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1161\/01.CIR.0000145167.30987.2E","article-title":"Prognostic significance of the long pentraxin PTX3 in acute myocardial infarction","volume":"110","author":"Latini","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jflm.2023.102599_bib121","first-page":"636","volume":"vol. 102","author":"Peri","year":"2000"},{"key":"10.1016\/j.jflm.2023.102599_bib122","doi-asserted-by":"crossref","first-page":"823","DOI":"10.3389\/fimmu.2019.00823","article-title":"Pentraxin 3 in cardiovascular disease","volume":"10","author":"Ristagno","year":"2019","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib123","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12979-016-0080-1","article-title":"The inflammatory protein Pentraxin 3 in cardiovascular disease","volume":"13","author":"Fornai","year":"2016","journal-title":"Immun Ageing"},{"issue":"1","key":"10.1016\/j.jflm.2023.102599_bib124","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-44472-0","article-title":"Postmortem plasma pentraxin 3 is a useful marker of fatal acute coronary syndrome","volume":"9","author":"Tojo","year":"2019","journal-title":"Sci Rep"}],"container-title":["Journal of Forensic and Legal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1752928X23001178?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1752928X23001178?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:18:28Z","timestamp":1761697108000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1752928X23001178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":124,"alternative-id":["S1752928X23001178"],"URL":"https:\/\/doi.org\/10.1016\/j.jflm.2023.102599","relation":{},"ISSN":["1752-928X"],"issn-type":[{"value":"1752-928X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Postmortem biochemistry in deaths from ischemic heart disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Forensic and Legal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jflm.2023.102599","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"102599"}}