{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:15:22Z","timestamp":1788538522037,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Forensic and Legal Medicine"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.jflm.2026.103163","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T15:16:18Z","timestamp":1777043778000},"page":"103163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Catalytic role of serum albumin in decarboxylation of acetoacetate: A biochemical insight into the study by Yoshida et al."],"prefix":"10.1016","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6011-6535","authenticated-orcid":false,"given":"Myu","family":"Tachibana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7631-4151","authenticated-orcid":false,"given":"Kei","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6367-0832","authenticated-orcid":false,"given":"Nobuhiro","family":"Yukawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jflm.2026.103163_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jflm.2025.102914","article-title":"Blood acetone concentrations in forensic autopsies are related to the food residue in stomach","volume":"114","author":"Yoshida","year":"2025","journal-title":"J Forensic Legal Med"},{"key":"10.1016\/j.jflm.2026.103163_bib2","first-page":"53","article-title":"[An autopsy case of alcoholic ketoacidosis","volume":"24","author":"Kinoshita","year":"2018","journal-title":"Forensic Pathol"},{"key":"10.1016\/j.jflm.2026.103163_bib3","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1071\/CH9671823","article-title":"Kinetics of the decarboxylation of acetoacetic acid","volume":"20","author":"Hay","year":"1967","journal-title":"Aust J Chem"},{"key":"10.1016\/j.jflm.2026.103163_bib4","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1520\/JFS14739J","article-title":"Beta-hydroxybutyric acid\u2212an indicator for an alcoholic ketoacidosis as cause of death in deceased alcohol abusers","volume":"45","author":"Iten","year":"2000","journal-title":"J Forensic Sci"},{"key":"10.1016\/j.jflm.2026.103163_bib5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jflm.2016.04.013","article-title":"Postmortem biochemistry in suspected starvation-induced ketoacidosis","volume":"42","author":"Palmiere","year":"2016","journal-title":"J Forensic Legal Med"},{"key":"10.1016\/j.jflm.2026.103163_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2021.110726","article-title":"Relationship between betahydroxybutyrate (BHB) and acetone concentrations in postmortem blood and cause of death","volume":"321","author":"Midtlyng","year":"2021","journal-title":"Forensic Sci Int"},{"key":"10.1016\/j.jflm.2026.103163_bib7","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1007\/s12024-025-00978-w","article-title":"Optimizing the postmortem diagnosis of alcoholic ketoacidosis","volume":"21","author":"Daniels","year":"2025","journal-title":"Forensic Sci Med Pathol"},{"key":"10.1016\/j.jflm.2026.103163_bib8","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0009-8981(72)90316-6","article-title":"Evidence for the existence of mammalian acetoacetate decarboxylase: with special reference to human blood serum","volume":"39","author":"Van Stekelenburg","year":"1972","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jflm.2026.103163_bib9","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0009-8981(76)90528-3","article-title":"Mammalian acetoacetate decarboxylase activity. Its distribution in subfractions of human albumin and occurrence in various tissues of the rat","volume":"71","author":"Koorevaar","year":"1976","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jflm.2026.103163_bib10","first-page":"37","article-title":"Acetoacetate decarboxylase activity of plasma components","volume":"15","author":"Kimura","year":"1986","journal-title":"Jap J Clin Chem"},{"key":"10.1016\/j.jflm.2026.103163_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/ijms252312627","article-title":"Albumin is an integrative protein of blood plasma and beyond","volume":"25","author":"Belinskaia","year":"2024","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jflm.2026.103163_bib12","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/jat\/34.9.549","article-title":"Determination of ketone bodies in blood by headspace gas chromatography-mass spectrometry","volume":"34","author":"Holm","year":"2010","journal-title":"J Anal Toxicol"},{"key":"10.1016\/j.jflm.2026.103163_bib13","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1021\/ed500645v","article-title":"Approaches to determining the oxidation state of nitrogen and carbon atoms in organic compounds for high school students","volume":"92","author":"Jurowski","year":"2015","journal-title":"J Chem Educ"},{"key":"10.1016\/j.jflm.2026.103163_bib14","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1021\/ed077p1428","article-title":"Assigning and using oxidation numbers in biochemistry lecture courses","volume":"77","author":"Halkides","year":"2000","journal-title":"J Chem Educ"},{"key":"10.1016\/j.jflm.2026.103163_bib15","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0379-0738(95)01783-6","article-title":"Alcoholic ketoacidosis as a cause of death in forensic cases","volume":"75","author":"Thomsen","year":"1995","journal-title":"Forensic Sci Int"},{"key":"10.1016\/j.jflm.2026.103163_bib16","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s12024-007-9018-4","article-title":"The postmortem distribution of ketone bodies between blood, vitreous humor, spinal fluid, and urine","volume":"4","author":"Felby","year":"2008","journal-title":"Forensic Sci Med Pathol"},{"key":"10.1016\/j.jflm.2026.103163_bib17","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.legalmed.2008.08.002","article-title":"Acetonaemia as an initial criterion of evaluation of a probable cause of sudden death","volume":"11","author":"Teresi\u0144ski","year":"2009","journal-title":"Leg Med (Tokyo)"},{"key":"10.1016\/j.jflm.2026.103163_bib18","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1021\/bi00867a002","article-title":"Acetoacetate decarboxylase. Identification of lysine at the active site","volume":"5","author":"Warren","year":"1966","journal-title":"Biochemistry"},{"key":"10.1016\/j.jflm.2026.103163_bib19","doi-asserted-by":"crossref","first-page":"7413","DOI":"10.1021\/ja00803a033","article-title":"Decarboxylation of Schiff bases","volume":"95","author":"Taguchi","year":"1973","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.jflm.2026.103163_bib20","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.1021\/acs.jcim.3c00241","article-title":"The catalytic mechanism of acetoacetate decarboxylase: a detailed study of Schiff base formation, protonation states, and their impact on catalysis","volume":"63","author":"Uranga","year":"2023","journal-title":"J Chem Inf Model"},{"key":"10.1016\/j.jflm.2026.103163_bib21","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.cca.2013.07.013","article-title":"Review: glycation of human serum albumin","volume":"425","author":"Anguizola","year":"2013","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jflm.2026.103163_bib22","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.cca.2019.11.007","article-title":"Glycated albumin","volume":"502","author":"Zendjabil","year":"2020","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jflm.2026.103163_bib23","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.4239\/wjd.v12.i7.1057","article-title":"Comprehensive overview of human serum albumin glycation in diabetes mellitus","volume":"12","author":"Qiu","year":"2021","journal-title":"World J Diabetes"},{"key":"10.1016\/j.jflm.2026.103163_bib24","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jphotobiol.2016.09.004","article-title":"The role of acetoacetate in amadori product formation of human serum albumin","volume":"163","author":"Bohlooli","year":"2016","journal-title":"J Photochem Photobiol, B"},{"key":"10.1016\/j.jflm.2026.103163_bib25","first-page":"2658","article-title":"Acetoacetate promotes the formation of fluorescent advanced glycation end products (AGEs)","volume":"34","author":"Bohlooli","year":"2016","journal-title":"J Biomol Struct Dyn"}],"container-title":["Journal of Forensic and Legal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1752928X26000958?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1752928X26000958?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T15:32:23Z","timestamp":1788535943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1752928X26000958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":25,"alternative-id":["S1752928X26000958"],"URL":"https:\/\/doi.org\/10.1016\/j.jflm.2026.103163","relation":{},"ISSN":["1752-928X"],"issn-type":[{"value":"1752-928X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Catalytic role of serum albumin in decarboxylation of acetoacetate: A biochemical insight into the study by Yoshida et al.","name":"articletitle","label":"Article Title"},{"value":"Journal of Forensic and Legal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jflm.2026.103163","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103163"}}