{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:11:59Z","timestamp":1778875919640,"version":"3.51.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,1,26]],"date-time":"2016-01-26T00:00:00Z","timestamp":1453766400000},"content-version":"vor","delay-in-days":1151,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Department of Health","award":["DOH94-HP-1802"],"award-info":[{"award-number":["DOH94-HP-1802"]}]},{"name":"Department of Health","award":["DOH95-HP-1802"],"award-info":[{"award-number":["DOH95-HP-1802"]}]},{"name":"Department of Health","award":["DOH96-HP-1702"],"award-info":[{"award-number":["DOH96-HP-1702"]}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"crossref","award":["NSC 97-2314-B-192-001-MY2"],"award-info":[{"award-number":["NSC 97-2314-B-192-001-MY2"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the Formosan Medical Association"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.jfma.2011.09.022","type":"journal-article","created":{"date-parts":[[2012,4,13]],"date-time":"2012-04-13T03:45:15Z","timestamp":1334288715000},"page":"711-718","source":"Crossref","is-referenced-by-count":9,"title":["Haemophilus influenzae type b combination vaccines and atopic disorders: A prospective cohort study"],"prefix":"10.1016","volume":"111","author":[{"given":"I-Jen","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Min","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yueliang Leon","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu-Shiun","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tien-Jen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pau-Chung","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jfma.2011.09.022_bib1","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1398-9995.2004.00526.x","article-title":"The global burden of asthma: executive summary of the GINA Dissemination Committee Report","volume":"59","author":"Masoli","year":"2004","journal-title":"Allergy"},{"key":"10.1016\/j.jfma.2011.09.022_bib2","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/j.1365-2567.2004.01925.x","article-title":"The increased prevalence of allergy and the hygiene hypothesis: missing immune deviation, reduced immune suppression, or both?","volume":"112","author":"Romagnani","year":"2004","journal-title":"Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib3","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.jaci.2007.11.034","article-title":"Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma","volume":"121","author":"McDonald","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib4","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.jaci.2006.12.672","article-title":"Is the prevalence of wheeze in children altered by neonatal BCG vaccination?","volume":"119","author":"Linehan","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib5","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1136\/thx.2006.062547","article-title":"Is childhood immunisation associated with atopic disease from age 7 to 32 years?","volume":"62","author":"Nakajima","year":"2007","journal-title":"Thorax"},{"key":"10.1016\/j.jfma.2011.09.022_bib6","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1136\/thx.53.11.927","article-title":"Early childhood infection and atopic disorder","volume":"53","author":"Farooqi","year":"1998","journal-title":"Thorax"},{"key":"10.1016\/j.jfma.2011.09.022_bib7","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1080\/00015550310014997","article-title":"Atopic dermatitis increased following vaccination for measles, mumps, and infection","volume":"83","author":"Olesen","year":"2003","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jfma.2011.09.022_bib8","first-page":"387","article-title":"Vaccination against influenzae type b and atopy in East German schoolchildren","volume":"7","author":"Laubereau","year":"2002","journal-title":"Eur J Med Res"},{"key":"10.1016\/j.jfma.2011.09.022_bib9","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/ppul.20397","article-title":"Haemophilus influenzae type b vaccination and reported atopic disorders in 8-12-year-old children","volume":"41","author":"Bernsen","year":"2006","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jfma.2011.09.022_bib10","doi-asserted-by":"crossref","first-page":"e367","DOI":"10.1542\/peds.2006-1479","article-title":"Diphtheria, pertussis, poliomyelitis, tetanus, and Haemophilus influenzae type b vaccinations and risk of eczema and recurrent wheeze in the first year of life: the KOALA Birth Cohort Study","volume":"119","author":"Kummeling","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.jfma.2011.09.022_bib11","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1086\/323342","article-title":"Immunization with Haemophilus influenzae type b-CRM(197) conjugate vaccine elicits a mixed Th1 and Th2 CD(4+) T cell cytokine response that correlates with the isotype of antipolysaccharide antibody","volume":"184","author":"Kamboj","year":"2001","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jfma.2011.09.022_bib12","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1399-3038.2007.00550.x","article-title":"Environmental risk factors for early infantile atopic dermatitis","volume":"18","author":"Wang","year":"2007","journal-title":"Pediatric Allergy Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib13","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1542\/peds.113.3.468","article-title":"Perinatal predictors of atopic dermatitis occurring in the first six months of life","volume":"113","author":"Moore","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jfma.2011.09.022_bib14","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1093\/aje\/kwh208","article-title":"Breastfeeding and risk of atopic dermatitis, by parental history of allergy, during the first 18 months of life","volume":"160","author":"Benn","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jfma.2011.09.022_bib15","doi-asserted-by":"crossref","first-page":"e519","DOI":"10.1542\/peds.2008-2867","article-title":"Efficacy of inhaled corticosteroids in infants and preschoolers with recurrent wheezing and asthma: a systematic review with meta-analysis","volume":"123","author":"Castro-Rodriguez","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.jfma.2011.09.022_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-2567.1998.00401.x","article-title":"Distinct T-cell subtypes induced with whole cell and acellular pertussis vaccines in children","volume":"93","author":"Ryan","year":"1998","journal-title":"Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib17","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1159\/000237376","article-title":"Specific IgE and IgG4 immune responses to tetanus and diphtheria toxoid in atopic and nonatopic children during the first two years of life","volume":"111","author":"Dannemann","year":"1996","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib18","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/0264-410X(94)00017-H","article-title":"Immunoglobulin E responses to diphtheria and tetanus toxoids after booster with aluminium-adsorbed and fluid DT-vaccines","volume":"13","author":"Mark","year":"1995","journal-title":"Vaccine"},{"key":"10.1016\/j.jfma.2011.09.022_bib19","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1111\/j.1398-9995.1998.tb03841.x","article-title":"Pertussis IgE and atopic disease","volume":"53","author":"Nilsson","year":"1998","journal-title":"Allergy"},{"key":"10.1016\/j.jfma.2011.09.022_bib20","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/S0140-6736(97)03257-1","article-title":"Host immunobiology and vaccine development","volume":"350","author":"Nossal","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.jfma.2011.09.022_bib21","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.4049\/jimmunol.164.5.2711","article-title":"A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian selfhsp70 homologue","volume":"164","author":"Wendling","year":"2000","journal-title":"J Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib22","doi-asserted-by":"crossref","first-page":"4147","DOI":"10.4049\/jimmunol.167.8.4147","article-title":"Induction of IL-10 and inhibition of experimental arthritis are specific features of microbial heat shock proteins that are absent for other evolutionarily conserved immunodominant proteins","volume":"167","author":"Prakken","year":"2001","journal-title":"J Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib23","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1159\/000113493","article-title":"Induction of antigen-specific immunity in human neonates and infants","volume":"61","author":"Wilson","year":"2008","journal-title":"Nestle Nutr Workshop Ser Pediatr Program"},{"key":"10.1016\/j.jfma.2011.09.022_bib24","doi-asserted-by":"crossref","first-page":"S105","DOI":"10.1164\/ajrccm.162.supplement_2.ras-10","article-title":"Perinatal events in relation to sensitization in the human","volume":"162","author":"Bj\u00f6rkst\u00e9n","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jfma.2011.09.022_bib25","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.jaci.2007.07.009","article-title":"Infant frequent wheezing correlated to Clara cell protein 10 (CC10) polymorphism and concentration, but not allergy sensitization, in a perinatal cohort study","volume":"120","author":"Yang","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib26","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1067\/mai.2001.117797","article-title":"Dog exposure in infancy decreases the subsequent risk of frequent wheeze but not of atopy","volume":"108","author":"Remes","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jfma.2011.09.022_bib27","series-title":"Atopic dermatitis","first-page":"21","article-title":"Epidemiology","author":"Charman","year":"2002"},{"key":"10.1016\/j.jfma.2011.09.022_bib28","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2340\/00015555924447","article-title":"Diagnostic features of atopic eczema","volume":"92","author":"Hanifin","year":"1980","journal-title":"Acta Dermatol Venereol"},{"key":"10.1016\/j.jfma.2011.09.022_bib29","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1067\/mjd.2000.107773","article-title":"The prevalence of atopic dermatitis in Oregon schoolchildren","volume":"43","author":"Laughter","year":"2000","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jfma.2011.09.022_bib30","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1111\/j.1365-2133.2005.06540.x","article-title":"Risk factors for atopic dermatitis in New Zealand children at 3.5 years of age","volume":"152","author":"Purvis","year":"2005","journal-title":"Br J Dermatol"}],"container-title":["Journal of the Formosan Medical Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092966461200085X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092966461200085X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T23:28:07Z","timestamp":1687390087000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S092966461200085X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":30,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S092966461200085X"],"URL":"https:\/\/doi.org\/10.1016\/j.jfma.2011.09.022","relation":{},"ISSN":["0929-6646"],"issn-type":[{"value":"0929-6646","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}