{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:00:36Z","timestamp":1790395236776,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018493","name":"Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["112YSR-08"],"award-info":[{"award-number":["112YSR-08"]}],"id":[{"id":"10.13039\/100018493","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Formosan Medical Association"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jfma.2026.08.009","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T20:58:09Z","timestamp":1787691489000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Intermittent phototherapy in neonatal hyperbilirubinemia: A pilot randomized controlled trial in Taiwan"],"prefix":"10.1016","author":[{"given":"Hsiao-Chin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Lin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Fang","family":"Elaine Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung-Ting","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka-Wai","family":"Tam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben-Chang","family":"Shia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Yen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jfma.2026.08.009_bib1","doi-asserted-by":"crossref","first-page":"F317","DOI":"10.1136\/adc.2008.150714","article-title":"Visual assessment of jaundice in term and late preterm infants","volume":"94","author":"Keren","year":"2009","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.jfma.2026.08.009_bib2","series-title":"Nelson's textbook of pediatrics","author":"Roberts","year":"2016"},{"issue":"1","key":"10.1016\/j.jfma.2026.08.009_bib3","doi-asserted-by":"crossref","first-page":"e170","DOI":"10.1542\/peds.2006-3499","article-title":"A comparison of alternative risk-assessment strategies for predicting significant neonatal hyperbilirubinemia in term and near-term infants","volume":"121","author":"Keren","year":"2008","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.jfma.2026.08.009_bib4","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1542\/peds.114.1.297","article-title":"Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation","volume":"114","year":"2004","journal-title":"Pediatrics"},{"issue":"9","key":"10.1016\/j.jfma.2026.08.009_bib5","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1056\/NEJMct0708376","article-title":"Phototherapy for neonatal jaundice","volume":"358","author":"Maisels","year":"2008","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.jfma.2026.08.009_bib6","first-page":"5","article-title":"The role of intensive phototherapy in decreasing the need for exchange transfusion in neonatal jaundice","volume":"64","author":"Edris","year":"2014","journal-title":"JPMA The Journal of the Pakistan Medical Association"},{"key":"10.1016\/j.jfma.2026.08.009_bib7","first-page":"26","article-title":"A comparative analysis of intermittent and continuous phototherapy in patients with neonatal jaundice","author":"Das","year":"2021","journal-title":"J Pharm Res Int"},{"issue":"7","key":"10.1016\/j.jfma.2026.08.009_bib8","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1001\/jamapediatrics.2020.0559","article-title":"Cycled phototherapy dose-finding study for extremely low-birth-weight infants: a randomized clinical trial","volume":"174","author":"Arnold","year":"2020","journal-title":"JAMA Pediatr"},{"issue":"6","key":"10.1016\/j.jfma.2026.08.009_bib9","doi-asserted-by":"crossref","DOI":"10.18203\/2349-3291.ijcp20194536","article-title":"A comparative study to determine intermittent versus continuous phototherapy for reducing neonatal hyperbilirubinemia at tertiary care hospital in chennai, Tamil Nadu, India","volume":"6","author":"Suri","year":"2019","journal-title":"International Journal of Contemporary Pediatrics"},{"issue":"2","key":"10.1016\/j.jfma.2026.08.009_bib10","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00431-014-2373-8","article-title":"Intermittent versus continuous phototherapy for the treatment of neonatal non-hemolytic moderate hyperbilirubinemia in infants more than 34 weeks of gestational age: a randomized controlled trial","volume":"174","author":"Sachdeva","year":"2015","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jfma.2026.08.009_bib11","first-page":"18","article-title":"Intermittent versus continuous phototherapy for reducing neonatal hyperbilirubinemia","author":"Niknafs","year":"2008","journal-title":"Iran J Pediatr (Engl Ed)"},{"issue":"3","key":"10.1016\/j.jfma.2026.08.009_bib12","article-title":"Intermittent phototherapy versus continuous phototherapy for neonatal jaundice","volume":"3","author":"Gottimukkala","year":"2023","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"10.1016\/j.jfma.2026.08.009_bib13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1136\/adc.2005.081224","article-title":"Post-phototherapy neonatal bilirubin rebound: a potential cause of significant hyperbilirubinaemia","volume":"91","author":"Kaplan","year":"2006","journal-title":"Arch Dis Child"},{"issue":"8","key":"10.1016\/j.jfma.2026.08.009_bib14","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1007\/s00431-024-05610-7","article-title":"Continuous versus intermittent phototherapy in treatment of neonatal jaundice: a randomized controlled trial","volume":"183","author":"Demirel","year":"2024","journal-title":"Eur J Pediatr"},{"issue":"1","key":"10.1016\/j.jfma.2026.08.009_bib15","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0022-3476(73)80014-9","article-title":"Controlled trial comparing agar, intermittent phototherapy, and continuous phototherapy for reducing neonatal hyperbilirubinemia","volume":"82","author":"Maurer","year":"1973","journal-title":"J Pediatr"},{"issue":"4","key":"10.1016\/j.jfma.2026.08.009_bib16","doi-asserted-by":"crossref","first-page":"446","DOI":"10.4103\/ijmr.IJMR_2156_18","article-title":"Comparison of efficacy, safety & satisfaction of intermittent versus continuous phototherapy in hyperbilirubinaemic newborns \u226535 week gestation: a randomized controlled trial","volume":"153","author":"Gottimukkala","year":"2021","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.jfma.2026.08.009_bib17","article-title":"Comparison of continuous with intermittent phototherapy in the treatment of neonatal jaundice","author":"Khaliq","year":"2016","journal-title":"J Postgrad Med Inst"},{"issue":"9","key":"10.1016\/j.jfma.2026.08.009_bib18","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1136\/adc.59.9.892","article-title":"Serum bilirubin kinetics in intermittent phototherapy of physiological jaundice","volume":"59","author":"Lau","year":"1984","journal-title":"Arch Dis Child"},{"issue":"3","key":"10.1016\/j.jfma.2026.08.009_bib19","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3126\/jnps.v40i3.29535","article-title":"Continuous vs intermittent phototherapy in the management of non-haemolytic neonatal hyperbilirubinemia - a randomised non - Inferiority study","volume":"40","author":"Patil","year":"2020","journal-title":"J Nepal Paediatr Soc"},{"issue":"3","key":"10.1016\/j.jfma.2026.08.009_bib20","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1159\/000527381","article-title":"The duration of neonatal phototherapy and allergic disorders: the Japan environment and children's study","volume":"184","author":"Hotta","year":"2023","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.jfma.2026.08.009_bib21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.eplepsyres.2016.05.004","article-title":"Neonatal hyperbilirubinemia and the risk of febrile seizures and childhood epilepsy","volume":"124","author":"Maimburg","year":"2016","journal-title":"Epilepsy Res"},{"issue":"4","key":"10.1016\/j.jfma.2026.08.009_bib22","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2018-0648","article-title":"Childhood seizures after phototherapy","volume":"142","author":"Newman","year":"2018","journal-title":"Pediatrics"},{"issue":"5","key":"10.1016\/j.jfma.2026.08.009_bib23","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1038\/s41390-024-03191-7","article-title":"Risk of childhood neoplasms related to neonatal phototherapy- a systematic review and meta-analysis","volume":"96","author":"Kuitunen","year":"2024","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jfma.2026.08.009_bib24","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jpeds.2022.01.046","article-title":"Association between neonatal phototherapy exposure and childhood neoplasm","volume":"245","author":"Bugaiski-Shaked","year":"2022","journal-title":"J Pediatr"},{"issue":"8","key":"10.1016\/j.jfma.2026.08.009_bib25","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1002\/ijc.32158","article-title":"Neonatal phototherapy and future risk of childhood cancer","volume":"145","author":"Auger","year":"2019","journal-title":"Int J Cancer"},{"issue":"6","key":"10.1016\/j.jfma.2026.08.009_bib26","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1542\/peds.87.6.797","article-title":"Intelligence at six years in relation to neonatal TSB levels: follow-up of the national institute of child health and human development clinical trial of phototherapy","volume":"87","author":"Scheidt","year":"1991","journal-title":"Pediatrics"},{"issue":"18","key":"10.1016\/j.jfma.2026.08.009_bib27","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1056\/NEJMoa0803024","article-title":"Aggressive vs. conservative phototherapy for infants with extremely low birth weight","volume":"359","author":"Morris","year":"2008","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.jfma.2026.08.009_bib28","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0022-3476(74)80471-3","article-title":"Effect of phototherapy in preterm infants on growth in the neonatal period","volume":"85","author":"Wu","year":"1974","journal-title":"J Pediatr"},{"issue":"2","key":"10.1016\/j.jfma.2026.08.009_bib29","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jbmt.2017.08.005","article-title":"The effect of tactile-kinesthetic stimulation on growth indices of healthy neonates","volume":"22","author":"Abedi","year":"2018","journal-title":"J Bodyw Mov Ther"},{"issue":"3","key":"10.1016\/j.jfma.2026.08.009_bib30","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2022-058859","article-title":"Clinical practice guideline revision: management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation","volume":"150","author":"Kemper","year":"2022","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.jfma.2026.08.009_bib31","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2023-063323","article-title":"Bilirubin measurement and phototherapy use after the AAP 2022 newborn hyperbilirubinemia guideline","volume":"153","author":"Sarathy","year":"2024","journal-title":"Pediatrics"}],"container-title":["Journal of the Formosan Medical Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0929664626007977?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0929664626007977?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:24:16Z","timestamp":1790393056000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0929664626007977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":31,"alternative-id":["S0929664626007977"],"URL":"https:\/\/doi.org\/10.1016\/j.jfma.2026.08.009","relation":{},"ISSN":["0929-6646"],"issn-type":[{"value":"0929-6646","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intermittent phototherapy in neonatal hyperbilirubinemia: A pilot randomized controlled trial in Taiwan","name":"articletitle","label":"Article Title"},{"value":"Journal of the Formosan Medical Association","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jfma.2026.08.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2026, Formosan Medical Association. Published by Elsevier Taiwan LLC. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}