{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T17:02:23Z","timestamp":1791651743163,"version":"4.3.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:p>An 8-year-old cat with recent-onset generalized seizures was diagnosed with a right forebrain mass using magnetic resonance imaging. The mass was excised and upon histologic and immunohistochemical examination shown to be a Toxoplasma gondii granuloma. Serology supported active T gondii infection. The cat was treated with phenobarbital to control seizures. After definitive diagnosis of toxoplasma granuloma, clindamycin was administered for approximately 1 month. Seizures recurred 8 months after initial presentation, and the cat was euthanased at the owner's request. This is a previously unreported manifestation of feline central nervous system toxoplasmosis. When a mass lesion is present in the brain of a cat and serologic test results support active infection with T gondii, toxoplasma granuloma must be a differential diagnosis. If the patient is suffering from clinical disease, surgical resection of the mass (if possible) can be complimented with medical treatment until definitive diagnosis is obtained. Immunocompromising factors should be identified and addressed if possible.<\/jats:p>","DOI":"10.1016\/j.jfms.2005.03.004","type":"journal-article","created":{"date-parts":[[2005,5,25]],"date-time":"2005-05-25T08:41:42Z","timestamp":1117010502000},"page":"369-374","source":"Crossref","is-referenced-by-count":32,"title":["Intracranial\n                    <i>Toxoplasma gondii<\/i>\n                    granuloma in a                     cat"],"prefix":"10.1177","volume":"7","author":[{"given":"Jessica C.","family":"Pfohl","sequence":"first","affiliation":[{"name":"Dallas Veterinary Surgical Center,\r                4444 Trinity Mills Road, Suite 203, Dallas, TX 75287, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis W.","family":"Dewey","sequence":"additional","affiliation":[{"name":"Staff Neurologist, Long Island\r                Veterinary Specialists, 163 South Service Road, Plainview, NY 11803, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2005,12,1]]},"reference":[{"key":"bibr1-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199605000-00019"},{"key":"bibr2-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.181.6.1811711"},{"key":"bibr3-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.73.5.0720"},{"key":"bibr4-j.jfms.2005.03.004","first-page":"127","volume-title":"A Practical Guide to Canine and Feline Neurology","author":"Dewey C.W.","year":"2003","edition":"1"},{"key":"bibr5-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050003"},{"key":"bibr6-j.jfms.2005.03.004","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.2460\/javma.1993.203.11.1556","volume":"203","author":"Dubey J.P.","year":"1993","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"bibr7-j.jfms.2005.03.004","first-page":"493","volume-title":"Infectious Diseases of the Dog and Cat","author":"Dubey J.P.","year":"1998","edition":"2"},{"key":"bibr8-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1177\/030098589603300305"},{"key":"bibr9-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182097008949"},{"key":"bibr10-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1998.tb01609.x"},{"key":"bibr11-j.jfms.2005.03.004","doi-asserted-by":"crossref","first-page":"316","DOI":"10.2460\/javma.1990.196.02.316","volume":"196","author":"Heidel J.R.","year":"1990","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"bibr12-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.7883\/yoken1952.22.319"},{"key":"bibr13-j.jfms.2005.03.004","doi-asserted-by":"crossref","unstructured":"Lappin M.R. Feline toxoplasmosis: interpretation of diagnostic test                         results, Seminars in Veterinary Medicine and Surgery                         (Small Animal), 1996,                         154\u2013160.","DOI":"10.1016\/S1096-2867(96)80027-2"},{"key":"bibr14-j.jfms.2005.03.004","first-page":"625","volume":"27","author":"Lappin M.R.","year":"1992","journal-title":"Journal of the American Animal Hospital Association"},{"key":"bibr15-j.jfms.2005.03.004","doi-asserted-by":"crossref","unstructured":"Lappin M.R., Greene C.E., Winston S.et                         al Clinical feline toxoplasmosis: serologic diagnosis and                         therapeutic management of 15 cases, Journal of                         Veterinary Internal Medicine, 1989,                         139\u2013143.","DOI":"10.1111\/j.1939-1676.1989.tb03089.x"},{"key":"bibr16-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.40.120"},{"key":"bibr17-j.jfms.2005.03.004","first-page":"1296","volume-title":"Small Animal Internal Medicine","author":"Nelson R.W.","year":"2003","edition":"3"},{"key":"bibr18-j.jfms.2005.03.004","first-page":"493","volume":"14","author":"Orefice G.","year":"1992","journal-title":"ACTA Neurologica"},{"key":"bibr19-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1007\/BF01402389"},{"key":"bibr20-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(18)30254-8"},{"key":"bibr21-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(02)00075-0"},{"key":"bibr22-j.jfms.2005.03.004","doi-asserted-by":"crossref","unstructured":"Schatzberg S.J., Haley N.J., Barr S.C.et                         al Use of a multiplex polymerase chain reaction assay in the                         antemortem diagnosis of toxoplasmosis and neosporosis in the central nervous                         system of cats and dogs, American Journal of                         Veterinary Research, 2003,                         1507\u20131713.","DOI":"10.2460\/ajvr.2003.64.1507"},{"key":"bibr23-j.jfms.2005.03.004","doi-asserted-by":"crossref","unstructured":"Stiles J., Prade R., Greene C. Detection of\n                      Toxoplasma gondii\n                      in feline and                         canine biological samples by use of the polymerase chain                         reaction, American Journal of Veterinary                         Research, 1996,                     264\u2013267.","DOI":"10.2460\/ajvr.1996.57.03.264"},{"key":"bibr24-j.jfms.2005.03.004","first-page":"153","volume-title":"Veterinary Immunology; An Introduction","author":"Tizard I.R.","year":"1996","edition":"5"},{"key":"bibr25-j.jfms.2005.03.004","first-page":"3","volume":"49","author":"Turner G.V.S.","year":"1978","journal-title":"Journal of the South African Veterinary Association"},{"key":"bibr26-j.jfms.2005.03.004","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.5.1061"},{"key":"bibr27-j.jfms.2005.03.004","first-page":"288","volume-title":"Kirk's Current Veterinary Therapy XIII: Small Animal Practice","author":"Zenger E.","year":"2000"}],"container-title":["Journal of Feline Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.jfms.2005.03.004","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1016\/j.jfms.2005.03.004","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.jfms.2005.03.004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:14:00Z","timestamp":1777500840000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1016\/j.jfms.2005.03.004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["10.1016\/j.jfms.2005.03.004"],"URL":"https:\/\/doi.org\/10.1016\/j.jfms.2005.03.004","relation":{},"ISSN":["1098-612X","1532-2750"],"issn-type":[{"value":"1098-612X","type":"print"},{"value":"1532-2750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}