{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:29:05Z","timestamp":1777850945619,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p>Parenteral administration of Crandell Rees feline kidney (CRFK) cell lysates or feline herpesvirus 1, calicivirus, and panleukopenia virus-containing vaccines (FVRCP) grown on CRFK cells induces antibodies against CRFK cells. These antibodies also react with feline renal cell extracts. The purpose of this study was to determine whether interstitial nephritis would be detected in cats that were immunologically sensitized with CRFK lysates, boosted with CRFK lysates, and then biopsied 2 weeks after the booster. Cats (2 per group) were immunologically sensitized against CRFK lysates by administering 10 \u03bcg, 50 \u03bcg, or 50 \u03bcg plus alum 13 times (12 times in the first 50 weeks) over 2 years. Two cats were inoculated three times, 4 weeks apart with an FVRCP vaccine for intranasal administration as kittens, boosted 50 and 102 weeks later, and then renal biopsies taken 2 weeks after the last booster. Neither of the cats vaccinated with the FVRCP for intranasal administration had detectable renal inflammation. One cat in each of the three CRFK lysate sensitization groups had lymphocytic\u2013plasmacytic interstitial nephritis.<\/jats:p>","DOI":"10.1016\/j.jfms.2006.03.003","type":"journal-article","created":{"date-parts":[[2006,5,22]],"date-time":"2006-05-22T10:57:11Z","timestamp":1148295431000},"page":"353-356","source":"Crossref","is-referenced-by-count":23,"title":["Interstitial nephritis in cats inoculated with Crandell Rees feline kidney cell lysates"],"prefix":"10.1177","volume":"8","author":[{"given":"Michael R.","family":"Lappin","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Colorado State University, Fort Collins, CO 80523-1678, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randall J.","family":"Basaraba","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wayne A.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Heska Corporation, 3760 Rocky Mountain Avenue, Loveland, CO 80538, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,10,1]]},"reference":[{"key":"bibr1-j.jfms.2006.03.003","doi-asserted-by":"publisher","DOI":"10.1007\/BF02618435"},{"key":"bibr2-j.jfms.2006.03.003","doi-asserted-by":"crossref","first-page":"744","DOI":"10.2460\/javma.1993.202.05.744","volume":"202","author":"DiBartola S.P.","year":"1993","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"bibr3-j.jfms.2006.03.003","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.5.1536-1547.1999"},{"key":"bibr4-j.jfms.2006.03.003","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2005.66.506"},{"key":"bibr5-j.jfms.2006.03.003","first-page":"539","volume":"59","author":"Lee K.M.","year":"1969","journal-title":"Cornell Veterinarian"},{"key":"bibr6-j.jfms.2006.03.003","first-page":"127","volume":"14","author":"Lulich J.P.","year":"1992","journal-title":"Compendium on Continuing Education for the Practicing Veterinarian"},{"key":"bibr7-j.jfms.2006.03.003","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1994.tb03952.x"},{"key":"bibr8-j.jfms.2006.03.003","first-page":"71","volume":"23","author":"Richards J.","year":"2001","journal-title":"Compendium on Continuing Education for the Practicing Veterinarian"},{"key":"bibr9-j.jfms.2006.03.003","first-page":"165","volume":"60","author":"Scott F.W.","year":"1970","journal-title":"Cornell Veterinarian"},{"key":"bibr10-j.jfms.2006.03.003","unstructured":"Tizard I.R. Veterinary Immunology, 7th edn, 2004, Saunders: Philadelphia, 239\u2013241."}],"container-title":["Journal of Feline Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.jfms.2006.03.003","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1016\/j.jfms.2006.03.003","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.jfms.2006.03.003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:14:12Z","timestamp":1777500852000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1016\/j.jfms.2006.03.003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1016\/j.jfms.2006.03.003"],"URL":"https:\/\/doi.org\/10.1016\/j.jfms.2006.03.003","relation":{},"ISSN":["1098-612X","1532-2750"],"issn-type":[{"value":"1098-612X","type":"print"},{"value":"1532-2750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}