{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:27:52Z","timestamp":1790623672747,"version":"4.1.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:p>Phaeochromocytomas are catecholamine-secreting tumours of the adrenal glands and are rare in cats. Plasma metanephrine levels are widely considered the diagnostic test of choice for phaeochromocytoma in people but have not been investigated in cats. In this study plasma free normetanephrine and metanephrine levels were measured using high-pressure liquid chromatography in healthy cats, sick cats with non-adrenal disease and in a cat with a suspected phaeochromocytoma. Plasma normetanephrine was significantly higher in sick cats with non-adrenal disease compared to healthy cats ( P&lt;0.05) and markedly higher in the cat with a suspected phaeochromocytoma when compared to either group. Plasma metanephrine was not significantly different in any of the groups. This study establishes a first-line guide reference range for plasma metanephrine and normetanephrine levels in healthy cats and cats with non-adrenal disease. These results provide rationale for further studies to establish the use of plasma normetanephrine levels as a potential diagnostic test for phaeochromocytoma in the cat.<\/jats:p>","DOI":"10.1016\/j.jfms.2009.10.010","type":"journal-article","created":{"date-parts":[[2010,2,17]],"date-time":"2010-02-17T04:39:50Z","timestamp":1266381590000},"page":"435-440","source":"Crossref","is-referenced-by-count":39,"title":["Plasma free metanephrines in healthy cats, cats with non-adrenal disease and a cat with suspected phaeochromocytoma"],"prefix":"10.1177","volume":"12","author":[{"given":"Justin A.","family":"Wimpole","sequence":"first","affiliation":[{"name":"Small Animal Specialist Hospital, 1\/1 Richardson Place North Ryde 2113, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl F.M.","family":"Adagra","sequence":"additional","affiliation":[{"name":"Small Animal Specialist Hospital, 1\/1 Richardson Place North Ryde 2113, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark F.","family":"Billson","sequence":"additional","affiliation":[{"name":"Small Animal Specialist Hospital, 1\/1 Richardson Place North Ryde 2113, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilo N.","family":"Pillai","sequence":"additional","affiliation":[{"name":"South Eastern Area Laboratory Services (SEALS) Department of Clinical Chemistry, Prince of Wales Hospital, Barker Street, Randwick 2031, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren J.","family":"Foster","sequence":"additional","affiliation":[{"name":"Small Animal Specialist Hospital, 1\/1 Richardson Place North Ryde 2113, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,6,1]]},"reference":[{"key":"bibr1-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1994.tb03222.x"},{"key":"bibr2-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1997.tb00464.x"},{"key":"bibr3-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1990.197.01.104"},{"key":"bibr4-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1993.tb03188.x"},{"key":"bibr5-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-33-1-33"},{"key":"bibr6-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(97)50037-4"},{"key":"bibr7-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(84)50080-1"},{"key":"bibr8-j.jfms.2009.10.010","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.2460\/javma.1987.191.12.1610","volume":"191","author":"Bouayad H.","year":"1987","journal-title":"J Am Vet Med Assoc"},{"key":"bibr9-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(16)30088-8"},{"key":"bibr10-j.jfms.2009.10.010","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.60.5.365"},{"key":"bibr11-j.jfms.2009.10.010","unstructured":"Francis R.C., Pickerodt P.A., Salewski L., Boemke W., Hohne C. 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