{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:29:19Z","timestamp":1777850959479,"version":"3.51.4"},"reference-count":60,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Feline Medicine and Surgery"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:p>Feline orofacial pain syndrome (FOPS) is a pain disorder of cats with behavioural signs of oral discomfort and tongue mutilation. This report describes the findings from a case series of 113 cats including 100 Burmese. FOPS is suspected to be a neuropathic pain disorder and the predominance within the Burmese cat breed suggests an inherited disorder, possibly involving central and\/or ganglion processing of sensory trigeminal information. The disease is characterised by an episodic, typically unilateral, discomfort with pain-free intervals. The discomfort is triggered, in many cases, by mouth movements. The disease is often recurrent and with time may become unremitting \u2014 12% of cases in this series were euthanased as a consequence of the condition. Sensitisation of trigeminal nerve endings as a consequence of oral disease or tooth eruption appears to be an important factor in the aetiology \u2014 63% of cases had a history of oral lesions and at least 16% experienced their first sign of discomfort during eruption of permanent teeth. External factors can also influence the disease as FOPS events could be directly linked to a situation causing anxiety in 20% of cats. FOPS can be resistant to traditional analgesics and in some cases successful management required anti-convulsants with an analgesic effect.<\/jats:p>","DOI":"10.1016\/j.jfms.2010.03.005","type":"journal-article","created":{"date-parts":[[2010,5,7]],"date-time":"2010-05-07T06:39:17Z","timestamp":1273214357000},"page":"498-508","source":"Crossref","is-referenced-by-count":60,"title":["Feline orofacial pain syndrome (FOPS): A retrospective study of 113 cases"],"prefix":"10.1177","volume":"12","author":[{"given":"Clare","family":"Rusbridge","sequence":"first","affiliation":[{"name":"Stone Lion Veterinary Centre, 41 High Street, Wimbledon SW19 5AU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Heath","sequence":"additional","affiliation":[{"name":"Behavioural Referrals Veterinary Practice, 10 Rushton Drive, Upton, Chester CH2 1RE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dani\u00e8lle A.","family":"Gunn-Moore","sequence":"additional","affiliation":[{"name":"Division of Veterinary Clinical Sciences, Royal (Dick) School of Veterinary Studies, University of Edinburgh Hospital for Small Animals, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan Penelope","family":"Knowler","sequence":"additional","affiliation":[{"name":"Stone Lion Veterinary Centre, 41 High Street, Wimbledon SW19 5AU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norman","family":"Johnston","sequence":"additional","affiliation":[{"name":"DentalVets, 31 Station Hill, North Berwick, East Lothian EH39 4AS,\u00a0UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angus Kennedy","family":"McFadyen","sequence":"additional","affiliation":[{"name":"Health Statistics, School of Engineering and Computing, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4\u00a00BA, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,6,1]]},"reference":[{"key":"bibr1-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1136\/vr.134.14.360-a"},{"key":"bibr2-j.jfms.2010.03.005","first-page":"660","volume":"149","author":"Heath S.","year":"2001","journal-title":"Vet Rec"},{"key":"bibr3-j.jfms.2010.03.005","first-page":"246","volume":"17","author":"Rusbridge C.","year":"2002","journal-title":"J Vet Intern Med"},{"key":"bibr4-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1126\/science.288.5472.1765"},{"key":"bibr5-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1054\/jpai.2000.9818"},{"key":"bibr6-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2008.12.017"},{"key":"bibr7-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.09.017"},{"key":"bibr8-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(89)90160-7"},{"key":"bibr9-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1038\/384360a0"},{"key":"bibr10-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.218.230"},{"key":"bibr11-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.12.2347"},{"key":"bibr12-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(05)70130-9"},{"key":"bibr13-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1024\/0040-5930.61.5.308"},{"key":"bibr14-j.jfms.2010.03.005","first-page":"458","volume":"51","author":"Pinto A.","year":"2003","journal-title":"Gen Dent"},{"key":"bibr15-j.jfms.2010.03.005","first-page":"29","volume":"64","author":"Muzyka B.C.","year":"1999","journal-title":"Cutis"},{"key":"bibr16-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(86)90146-1"},{"key":"bibr17-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(91)90202-K"},{"key":"bibr18-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2001.95.3.0513"},{"key":"bibr19-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198905000-00018"},{"key":"bibr20-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(96)71547-5"},{"key":"bibr21-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-199409000-00002"},{"key":"bibr22-j.jfms.2010.03.005","first-page":"232","volume":"13","author":"Ku\u011fu N.","year":"2002","journal-title":"Turk Psikiyatri Derg"},{"key":"bibr23-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-7085.2003.03037.x"},{"key":"bibr24-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.2741\/3598"},{"key":"bibr25-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2008.00379.x"},{"key":"bibr26-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2008.09.001"},{"key":"bibr27-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2006.12.007"},{"key":"bibr28-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1177\/00220345750540021801"},{"key":"bibr29-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1681.2001.03431.x"},{"key":"bibr30-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1155\/2006\/651712"},{"key":"bibr31-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200060050-00005"},{"key":"bibr32-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(93)50311-X"},{"key":"bibr33-j.jfms.2010.03.005","first-page":"309","volume":"54","author":"Cochrane S.M.","year":"1990","journal-title":"Can J Vet Res"},{"key":"bibr34-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1996.209.03.618"},{"key":"bibr35-j.jfms.2010.03.005","first-page":"101","volume-title":"Epilepsy in children and adolescents","author":"Hannah J.A.","year":"1995","edition":"1"},{"key":"bibr36-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2009.05.007"},{"key":"bibr37-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2006.04602.x"},{"key":"bibr38-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2006.07.012"},{"key":"bibr39-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4856-05.2006"},{"key":"bibr40-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-3589(06)54001-3"},{"key":"bibr41-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e3181775ac3"},{"key":"bibr42-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1002\/neu.20094"},{"key":"bibr43-j.jfms.2010.03.005","doi-asserted-by":"crossref","unstructured":"Siqueira S.R., Alves B., Malpartida H.M., Teixeira M.J., Siqueira J.T. Abnormal expression of voltage-gated sodium channels Nav1.7. Nav1.3 and Nav1.8 in trigeminal neuralgia, Neuroscience, 2009 Aug 20, (Epub ahead of print)","DOI":"10.1016\/j.neuroscience.2009.08.037"},{"key":"bibr44-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2007.08.004"},{"key":"bibr45-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2660(08)01004-3"},{"key":"bibr46-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3443-08.2008"},{"key":"bibr47-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2008.07.055"},{"key":"bibr48-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.03.018"},{"key":"bibr49-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1999.214.01.71"},{"key":"bibr50-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1998.213.09.1282"},{"key":"bibr51-j.jfms.2010.03.005","first-page":"628","volume":"1","author":"Schwartz-Porsche D.","year":"1989","journal-title":"Probl Vet Med"},{"key":"bibr52-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1999.tb02235.x"},{"key":"bibr53-j.jfms.2010.03.005","first-page":"1291","volume":"77","author":"Krafft R.M.","year":"2008","journal-title":"Am Fam Physician"},{"key":"bibr54-j.jfms.2010.03.005","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.33588\/rn.2912.98475","volume":"12","author":"Guerrero-Figueroa R.","year":"1999","journal-title":"Rev Neurol"},{"key":"bibr55-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01483.x"},{"key":"bibr56-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2005.11.005"},{"key":"bibr57-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.03.006"},{"key":"bibr58-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02585.x"},{"key":"bibr59-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2007000500011"},{"key":"bibr60-j.jfms.2010.03.005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2006.00152.x"}],"container-title":["Journal of Feline Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.jfms.2010.03.005","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1016\/j.jfms.2010.03.005","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1016\/j.jfms.2010.03.005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:14:22Z","timestamp":1777500862000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1016\/j.jfms.2010.03.005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":60,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1016\/j.jfms.2010.03.005"],"URL":"https:\/\/doi.org\/10.1016\/j.jfms.2010.03.005","relation":{},"ISSN":["1098-612X","1532-2750"],"issn-type":[{"value":"1098-612X","type":"print"},{"value":"1532-2750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}