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While an ante-mortem diagnosis of toxoplasmosis was considered possible based on the neuroanatomical diagnosis of central nervous system (CNS) disease primarily involving spinal cord segment C6\u2013T2 and the progressive elimination of other potential causes, Toxoplasma gondii antibody titres were consistent with previous exposure rather than active infection. A poor response to appropriate therapy did not support a diagnosis of toxoplasmosis. A post-mortem morphological diagnosis of marked segmental non-suppurative myelitis and necrosis, and an aetiological diagnosis of toxoplasmosis were made. The clinical and pathological findings are supportive of CNS inflammation due to reactivation of latent tissue T gondii cysts.<\/jats:p>","DOI":"10.1016\/j.jfms.2010.05.002","type":"journal-article","created":{"date-parts":[[2010,8,3]],"date-time":"2010-08-03T06:31:02Z","timestamp":1280817062000},"page":"818-821","source":"Crossref","is-referenced-by-count":21,"title":["Myelitis due to reactivated spinal toxoplasmosis in a cat"],"prefix":"10.1177","volume":"12","author":[{"given":"Scott A.","family":"Lindsay","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia\r\u00a0scott.lindsay@sydney.edu.au"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa R.","family":"Barrs","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgina","family":"Child","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia A.","family":"Beatty","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark B.","family":"Krockenberger","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,10,1]]},"reference":[{"key":"atypb1","unstructured":"Tizzard\u00a0I.R.Acquired immunity to parasites. 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