{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T01:32:11Z","timestamp":1768008731858,"version":"3.49.0"},"reference-count":78,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal Fran\u00e7ais d'Ophtalmologie"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.jfo.2017.12.004","type":"journal-article","created":{"date-parts":[[2018,3,22]],"date-time":"2018-03-22T01:47:09Z","timestamp":1521683229000},"page":"262-270","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Vieillissement de la surface oculaire\u00a0: physiopathologie et cons\u00e9quences pratiques pour la prise en charge"],"prefix":"10.1016","volume":"41","author":[{"given":"T.","family":"Audelan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Legrand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"M\u2019Garrech","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.-L.","family":"Best","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Barreau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Labetoulle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rousseau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jfo.2017.12.004_bib0395","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.jtos.2017.05.008","article-title":"TFOS DEWS II Definition and Classification Report","volume":"15","author":"Craig","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jfo.2017.12.004_bib0400","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jtos.2017.03.006","article-title":"TFOS DEWS II Tear Film Report","volume":"15","author":"Willcox","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jfo.2017.12.004_bib0405","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.jtos.2017.04.001","article-title":"TFOS DEWS II Sex, gender, and hormones report","volume":"15","author":"Sullivan","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jfo.2017.12.004_bib0410","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.jtos.2017.05.004","article-title":"TFOS DEWS II iatrogenic report","volume":"15","author":"Gomes","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jfo.2017.12.004_bib0415","series-title":"Esp\u00e9rance de vie \u00e0 la naissance","author":"Insee","year":"2017"},{"key":"10.1016\/j.jfo.2017.12.004_bib0420","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1001\/archopht.118.9.1264","article-title":"Prevalence of and risk factors for dry eye syndrome","volume":"118","author":"Moss","year":"2000","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0425","series-title":"Surface Oculaire","first-page":"139","article-title":"L\u2019oeil sec\u00a0: \u00e9pid\u00e9miologie","author":"Tahiri Joutei Hassani","year":"2015"},{"key":"10.1016\/j.jfo.2017.12.004_bib0430","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jtos.2017.05.003","article-title":"TFOS DEWS II Epidemiology Report","volume":"15","author":"Stapleton","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jfo.2017.12.004_bib0435","first-page":"S102","article-title":"Prevalence, burden, and pharmacoeconomics of dry eye disease","volume":"14","author":"Pflugfelder","year":"2008","journal-title":"Am J Manag Care"},{"key":"10.1016\/j.jfo.2017.12.004_bib0440","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1097\/ICO.0b013e3181f7f363","article-title":"The economic burden of dry eye disease in the United States: a decision tree analysis","volume":"30","author":"Yu","year":"2011","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2017.12.004_bib0445","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.exger.2013.04.002","article-title":"Calorie restriction (CR) and CR mimetics for the prevention and treatment of age-related eye disorders","volume":"48","author":"Kawashima","year":"2013","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0450","series-title":"Surface Oculaire","first-page":"164","article-title":"Le vieillissement de la surface oculaire","author":"Tsubota","year":"2015"},{"key":"10.1016\/j.jfo.2017.12.004_bib0455","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/ICO.0b013e31826a05a8","article-title":"The antiaging approach for the treatment of dry eye","volume":"31","author":"Tsubota","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2017.12.004_bib0460","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1001\/jama.295.13.1539","article-title":"Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial","volume":"295","author":"Heilbronn","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.jfo.2017.12.004_bib0465","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.bbrc.2010.06.018","article-title":"Calorie restriction: a new therapeutic intervention for age-related dry eye disease in rats","volume":"397","author":"Kawashima","year":"2010","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jfo.2017.12.004_bib0470","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/j.ajpath.2012.01.019","article-title":"Age-related dysfunction of the lacrimal gland and oxidative stress: evidence from the Cu, Zn-superoxide dismutase-1 (Sod1) knockout mice","volume":"180","author":"Kojima","year":"2012","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0475","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1167\/iovs.06-1027","article-title":"Involvement of oxidative stress on corneal epithelial alterations in a blink-suppressed dry eye","volume":"48","author":"Nakamura","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0480","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1038\/eye.2008.78","article-title":"Alterations of the tear film and ocular surface health in chronic smokers","volume":"22","author":"Matsumoto","year":"2008","journal-title":"Eye"},{"key":"10.1016\/j.jfo.2017.12.004_bib0485","first-page":"289","article-title":"Age-related changes in the rat lacrimal gland: specific morphology and unknown nature","volume":"45","author":"Gancharova","year":"2014","journal-title":"Ontogenez"},{"key":"10.1016\/j.jfo.2017.12.004_bib0490","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/path.1711430104","article-title":"Post-mortem prevalence of lymphocytic infiltration of the lacrymal gland: a comparative study in autoimmune and non-autoimmune diseases","volume":"143","author":"Nasu","year":"1984","journal-title":"J Pathol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0495","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1542-0124(12)70177-5","article-title":"The aging lacrimal gland: changes in structure and function","volume":"6","author":"Rocha","year":"2008","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jfo.2017.12.004_bib0500","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1755-3768.1987.tb06991.x","article-title":"Expressibility of meibomian secretion. Relation to age, lipid precorneal film, scales, foam, hair and pigmentation","volume":"65","author":"Norn","year":"1987","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0505","first-page":"765","article-title":"Histopathological study of the meibomian glands in 72\u00a0autopsy cases","volume":"98","author":"Obata","year":"1994","journal-title":"Nippon Ganka Gakkai Zasshi"},{"key":"10.1016\/j.jfo.2017.12.004_bib0510","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/00003226-199207000-00012","article-title":"Age-related morphological changes in lid margin and meibomian gland anatomy","volume":"11","author":"Hykin","year":"1992","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2017.12.004_bib0515","doi-asserted-by":"crossref","first-page":"4735","DOI":"10.1167\/iovs.13-11914","article-title":"The aging Meibomian gland: an in vivo confocal study","volume":"54","author":"Villani","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0520","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1001\/archopht.124.9.1286","article-title":"Influence of aging on the polar and neutral lipid profiles in human meibomian gland secretions","volume":"124","author":"Sullivan","year":"2006","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0525","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3109\/02713689308999471","article-title":"The casual level of meibomian lipids in humans","volume":"12","author":"Chew","year":"1993","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jfo.2017.12.004_bib0530","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/S0161-6420(94)31293-0","article-title":"Lacrimal testing. Age as a factor in Jones testing","volume":"101","author":"Hagele","year":"1994","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2017.12.004_bib0535","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0002-9394(14)70490-8","article-title":"Evaluation of the lacrimal drainage function by the drop test","volume":"122","author":"Sahlin","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0540","doi-asserted-by":"crossref","DOI":"10.1167\/iovs.13-12840","article-title":"Age-related changes and diseases of the ocular surface and cornea","volume":"54","author":"Gipson","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0545","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1167\/iovs.10-6997c","article-title":"The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland","volume":"52","author":"Knop","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0550","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1136\/bjo.68.5.316","article-title":"Normal tear protein profiles and age-related changes","volume":"68","author":"McGill","year":"1984","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0555","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1136\/bjo.81.10.824","article-title":"Aging and the lacrimal system","volume":"81","author":"Van Haeringen","year":"1997","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0560","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1755-3768.1988.tb08540.x","article-title":"Impact of aging and gender on the Ig-containing cell profile of the lacrimal gland","volume":"66","author":"Hann","year":"1988","journal-title":"Acta Ophthalmol (Copenh)"},{"key":"10.1016\/j.jfo.2017.12.004_bib0565","first-page":"1429","article-title":"Role of proinflammatory cytokines in the impaired lacrimation associated with autoimmune xerophthalmia","volume":"43","author":"Zoukhri","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0570","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1136\/bjo.62.11.800","article-title":"Morphological changes in the human conjunctival epithelium. II. In keratoconjunctivitis sicca","volume":"62","author":"Abdel-Khalek","year":"1978","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0575","first-page":"240","article-title":"The influence of age on the sensitivity of the cornea","volume":"16","author":"Millodot","year":"1977","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0580","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1159\/000079478","article-title":"Age-related modifications of corneal sensitivity","volume":"218","author":"Roszkowska","year":"2004","journal-title":"Ophthalmologica"},{"key":"10.1016\/j.jfo.2017.12.004_bib0585","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1136\/bjo.2006.112656","article-title":"Age-related differences in the normal human cornea: a laser scanning in vivo confocal microscopy study","volume":"91","author":"Niederer","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0590","doi-asserted-by":"crossref","first-page":"838","DOI":"10.2337\/dc14-2311","article-title":"Normative values for corneal nerve morphology assessed using corneal confocal microscopy: a multinational normative data set","volume":"38","author":"Tavakoli","year":"2015","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jfo.2017.12.004_bib0595","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1136\/bjo.84.1.76","article-title":"Identification of androgen receptor protein and 5alpha-reductase mRNA in human ocular tissues","volume":"84","author":"Rocha","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0600","doi-asserted-by":"crossref","first-page":"162","DOI":"10.3109\/02713683.2014.966847","article-title":"Sex-steroid imbalance in females and dry eye","volume":"40","author":"Versura","year":"2015","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jfo.2017.12.004_bib0605","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1001\/jama.286.17.2114","article-title":"Hormone replacement therapy and dry eye syndrome","volume":"286","author":"Schaumberg","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.jfo.2017.12.004_bib0610","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1167\/iovs.12-10457","article-title":"The effects of estrogen and androgen on tear secretion and matrix metalloproteinase-2\u00a0expression in lacrimal glands of ovariectomized rats","volume":"55","author":"Song","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0615","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/BF02738800","article-title":"Androgen support of lacrimal gland function","volume":"6","author":"Azzarolo","year":"1997","journal-title":"Endocrine"},{"key":"10.1016\/j.jfo.2017.12.004_bib0620","first-page":"1261","article-title":"Does androgen insufficiency cause lacrimal gland inflammation and aqueous tear deficiency?","volume":"40","author":"Sullivan","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0625","first-page":"592","article-title":"Androgen influence on lacrimal gland apoptosis, necrosis, and lymphocytic infiltration","volume":"40","author":"Azzarolo","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0630","first-page":"3002","article-title":"Testosterone-induced suppression of autoimmune disease in lacrimal tissue of a mouse model (NZB\/NZW F1) of Sjogren's syndrome","volume":"32","author":"Vendramini","year":"1991","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0635","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1097\/00003226-199811000-00002","article-title":"The pathology of dry eye: the interaction between the ocular surface and lacrimal glands","volume":"17","author":"Stern","year":"1998","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2017.12.004_bib0640","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1136\/bjophthalmol-2012-302705","article-title":"Low levels of 17-beta-oestradiol, oestrone and testosterone correlate with severe evaporative dysfunctional tear syndrome in postmenopausal women: a case-control study","volume":"98","author":"Gagliano","year":"2014","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0645","first-page":"4874","article-title":"Effect of androgen deficiency on the human meibomian gland and ocular surface","volume":"85","author":"Krenzer","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jfo.2017.12.004_bib0650","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1001\/archopht.120.12.1689","article-title":"Complete androgen insensitivity syndrome: effect on human meibomian gland secretions","volume":"120","author":"Sullivan","year":"2002","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0655","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1159\/000095771","article-title":"Androgen status of the nonautoimmune dry eye subtypes","volume":"38","author":"Tamer","year":"2006","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.jfo.2017.12.004_bib0660","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1167\/iovs.10-6997e","article-title":"The international workshop on meibomian gland dysfunction: report of the subcommittee on the epidemiology of, and associated risk factors for, MGD","volume":"52","author":"Schaumberg","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2017.12.004_bib0665","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2008.07.010","article-title":"Changes of conjunctivochalasis with age in a hospital-based study","volume":"147","author":"Mimura","year":"2009","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0670","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1186\/1471-2458-11-198","article-title":"Assessing the severity of conjunctivochalasis in a senile population: a community-based epidemiology study in Shanghai, China","volume":"11","author":"Zhang","year":"2011","journal-title":"BMC Public Health"},{"key":"10.1016\/j.jfo.2017.12.004_bib0675","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2012.07.014","article-title":"Increasing prevalence and severity of conjunctivochalasis with aging detected by anterior segment optical coherence tomography","volume":"155","author":"Gumus","year":"2013","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0680","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0039-6257(98)00037-X","article-title":"Conjunctivochalasis: literature review and possible pathophysiology","volume":"43","author":"Meller","year":"1998","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0685","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1097\/01.ico.0000178740.14212.1a","article-title":"Clinical impact of conjunctivochalasis on the ocular surface","volume":"24","author":"Yokoi","year":"2005","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2017.12.004_bib0690","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1016\/j.ophtha.2013.01.007","article-title":"Conjunctivochalasis interferes with tear flow from fornix to tear meniscus","volume":"120","author":"Huang","year":"2013","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2017.12.004_bib0695","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1001\/jamadermatol.2014.27","article-title":"Intrinsic and extrinsic risk factors for sagging eyelids","volume":"150","author":"Jacobs","year":"2014","journal-title":"JAMA Dermatol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0700","doi-asserted-by":"crossref","first-page":"328","DOI":"10.5935\/0004-2749.20150087","article-title":"Eyelid aging: pathophysiology and clinical management","volume":"78","author":"Damasceno","year":"2015","journal-title":"Arq Bras Oftalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0705","first-page":"247","article-title":"The epidemiology of Sjogren's syndrome","volume":"6","author":"Patel","year":"2014","journal-title":"Clin Epidemiol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0710","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1212\/01.WNL.0000103444.45882.D8","article-title":"Ophthalmologic features of Parkinson's disease","volume":"62","author":"Biousse","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jfo.2017.12.004_bib0715","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1097\/ICO.0b013e3182574ade","article-title":"Corneal sensitivity, blink rate, and corneal nerve density in progressive supranuclear palsy and Parkinson disease","volume":"32","author":"Reddy","year":"2013","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2017.12.004_bib0720","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/eye.2012.119","article-title":"Incidence, presenting features, and diagnosis of cicatrising conjunctivitis in the United Kingdom","volume":"26","author":"Radford","year":"2012","journal-title":"Eye"},{"key":"10.1016\/j.jfo.2017.12.004_bib0725","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.ophtha.2007.10.009","article-title":"Herpes zoster ophthalmicus natural history, risk factors, clinical presentation, and morbidity","volume":"115","author":"Liesegang","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2017.12.004_bib0730","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/ICU.0000000000000227","article-title":"Mechanisms and management of dry eye in cataract surgery patients","volume":"27","author":"Sutu","year":"2016","journal-title":"Curr Opinophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0735","series-title":"Surface oculaire","first-page":"442","article-title":"Iatrog\u00e9nie des traitements syst\u00e9miques","author":"Barreau","year":"2015"},{"key":"10.1016\/j.jfo.2017.12.004_bib0740","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.jfo.2010.12.005","article-title":"Managing treatment side effects: the respective roles of the active ingredient and the preservative","volume":"34","author":"Aptel","year":"2011","journal-title":"J Fr Ophtalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0745","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.preteyeres.2010.03.001","article-title":"Preservatives in eyedrops: the good, the bad and the ugly","volume":"29","author":"Baudouin","year":"2010","journal-title":"Progr Retin Eye Res"},{"key":"10.1016\/j.jfo.2017.12.004_bib0750","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1159\/000131086","article-title":"Surgery of the conjunctiva","volume":"41","author":"Yokoi","year":"2008","journal-title":"Dev Ophthalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0755","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.jfo.2011.01.018","article-title":"Efficacy assessment of Nutrilarm\u00ae, a per os omega-3\u00a0and omega-6\u00a0polyunsaturated essential fatty acid dietary formulation versus placebo in patients with bilateral treated moderate dry eye syndrome","volume":"34","author":"Creuzot-Garcher","year":"2011","journal-title":"J Fr Ophtalmol"},{"key":"10.1016\/j.jfo.2017.12.004_bib0760","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ophtha.2016.09.023","article-title":"A randomized, double-masked, placebo-controlled clinical trial of two forms of omega-3\u00a0supplements for treating dry eye disease","volume":"124","author":"Deinema","year":"2017","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2017.12.004_bib0765","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.2147\/CIA.S48955","article-title":"A randomized, double-masked study to evaluate the effect of omega-3\u00a0fatty acids supplementation in meibomian gland dysfunction","volume":"8","author":"Olenik","year":"2013","journal-title":"Clin Interv Aging"},{"key":"10.1016\/j.jfo.2017.12.004_bib0770","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/j.1538-7836.2008.02844.x","article-title":"Risk of major bleeding during concomitant use of antibiotic drugs and coumarin anticoagulants","volume":"6","author":"Penning-van Beest","year":"2008","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jfo.2017.12.004_bib0775","series-title":"Proposition de gestion des nouveaux anticoagulants oraux directs (AOD) en chirurgie ophtalmologique\u00a0: avis d\u2019experts","year":"2013"},{"key":"10.1016\/j.jfo.2017.12.004_bib0390","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/j.1755-3768.2007.01155.x","article-title":"Self-application of single-use eyedrop containers in an elderly population: comparisons with standard eyedrop bottle and with younger patients","volume":"86","author":"Dietlein","year":"2008","journal-title":"Acta Ophthalmol"}],"container-title":["Journal Fran\u00e7ais d'Ophtalmologie"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0181551218300925?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0181551218300925?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T19:08:04Z","timestamp":1759259284000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0181551218300925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":78,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S0181551218300925"],"URL":"https:\/\/doi.org\/10.1016\/j.jfo.2017.12.004","relation":{},"ISSN":["0181-5512"],"issn-type":[{"value":"0181-5512","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vieillissement de la surface oculaire\u00a0: physiopathologie et cons\u00e9quences pratiques pour la prise en charge","name":"articletitle","label":"Article Title"},{"value":"Journal Fran\u00e7ais d'Ophtalmologie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jfo.2017.12.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}