{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T12:29:54Z","timestamp":1785846594190,"version":"3.56.0"},"reference-count":182,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"am","delay-in-days":356,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal Fran\u00e7ais d'Ophtalmologie"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.jfo.2020.07.002","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T08:37:44Z","timestamp":1600677464000},"page":"1078-1095","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Corneal crosslinking in keratoconus management"],"prefix":"10.1016","volume":"43","author":[{"given":"S.","family":"Saad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Saad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Jouve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Kallel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Trinh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Goemaere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Borderie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Bouheraoua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jfo.2020.07.002_bib0005","doi-asserted-by":"crossref","first-page":"795738","DOI":"10.1155\/2015\/795738","article-title":"The genetic and environmental factors for keratoconus","volume":"2015","author":"Gordon-Shaag","year":"2015","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.jfo.2020.07.002_bib0010","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.ophtha.2007.03.073","article-title":"Risk assessment for ectasia after corneal refractive surgery","volume":"115","author":"Randleman","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2020.07.002_bib0015","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1006\/exer.1997.0410","article-title":"Induction of cross-links in corneal tissue","volume":"66","author":"Spoerl","year":"1998","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0020","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1007\/s003470050219","article-title":"Artificial stiffening of the cornea by induction of intrastromal cross-links","volume":"94","author":"Sp\u00f6rl","year":"1997","journal-title":"Der Ophthalmologe"},{"key":"10.1016\/j.jfo.2020.07.002_bib0025","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","article-title":"Riboflavin\/ultraviolet-a\u2013induced collagen crosslinking for the treatment of keratoconus","volume":"135","author":"Wollensak","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0030","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.survophthal.2015.04.002","article-title":"Corneal cross-linking","volume":"60","author":"Randleman","year":"2015","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0035","doi-asserted-by":"crossref","first-page":"13011","DOI":"10.1074\/jbc.M110.169813","article-title":"Effects of ultraviolet-A and riboflavin on the interaction of collagen and proteoglycans during corneal cross-linking","volume":"286","author":"Zhang","year":"2011","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jfo.2020.07.002_bib0040","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1016\/S0886-3350(03)00407-3","article-title":"Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross-linking","volume":"29","author":"Wollensak","year":"2003","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0045","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jtos.2013.01.002","article-title":"Corneal crosslinking with riboflavin and ultraviolet A. I. Principles","volume":"11","author":"Raiskup","year":"2013","journal-title":"Ocular Surf"},{"key":"10.1016\/j.jfo.2020.07.002_bib0050","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jcrs.2005.12.092","article-title":"Biomechanical evidence of the distribution of cross-links in corneas treated with riboflavin and ultraviolet A light","volume":"32","author":"Kohlhaas","year":"2006","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0055","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.jcrs.2006.11.015","article-title":"Hydration behavior of porcine cornea crosslinked with riboflavin and ultraviolet A","volume":"33","author":"Wollensak","year":"2007","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0060","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/01.ico.0000105827.85025.7f","article-title":"Collagen fiber diameter in the rabbit cornea after collagen crosslinking by riboflavin\/UVA","volume":"23","author":"Wollensak","year":"2004","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0065","first-page":"1526","article-title":"Keratoconus corneal architecture after riboflavin\/ultraviolet A cross-linking: ultrastructural studies","volume":"19","author":"Akhtar","year":"2013","journal-title":"Mol Vis"},{"key":"10.1016\/j.jfo.2020.07.002_bib0070","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/02713680490513182","article-title":"Increased resistance of crosslinked cornea against enzymatic digestion","volume":"29","author":"Spoerl","year":"2004","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0075","series-title":"Controversies in the management of keratoconus","first-page":"83","article-title":"The role of oxygen in corneal cross-linking","author":"Torres-Netto","year":"2019"},{"key":"10.1016\/j.jfo.2020.07.002_bib0080","doi-asserted-by":"crossref","first-page":"S85","DOI":"10.3928\/1081597X-20080101-15","article-title":"Depth-dependent cohesive tensile strength in human donor corneas: implications for refractive surgery","volume":"24","author":"Randleman","year":"2008","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0085","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jcrs.2004.10.044","article-title":"Determining in vivo biomechanical properties of the cornea with an ocular response analyzer","volume":"31","author":"Luce","year":"2005","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0090","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1167\/iovs.04-0694","article-title":"Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes","volume":"48","author":"Shah","year":"2007","journal-title":"Investig Ophthalmol Visual Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0095","doi-asserted-by":"crossref","first-page":"479","DOI":"10.3928\/1081597X-20160502-02","article-title":"Enhanced combined tomography and biomechanics data for distinguishing forme fruste keratoconus","volume":"32","author":"Luz","year":"2016","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0100","doi-asserted-by":"crossref","first-page":"18","DOI":"10.5935\/0004-2749.20190003","article-title":"Effect of accelerated corneal crosslinking on ocular response analyzer waveform-derived parameters in progressive keratoconus","volume":"82","author":"Uzel","year":"2019","journal-title":"Arq Bras Oftalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0105","doi-asserted-by":"crossref","first-page":"160","DOI":"10.4274\/tjo.56750","article-title":"Evaluation of corneal biomechanical changes after collagen crosslinking in patients with progressive keratoconus by ocular response analyzer","volume":"48","author":"Kucumen","year":"2018","journal-title":"Turk J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0110","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.optom.2014.05.006","article-title":"Long-term results of corneal collagen crosslinking for progressive keratoconus","volume":"8","author":"De Bernardo","year":"2015","journal-title":"J Optom"},{"key":"10.1016\/j.jfo.2020.07.002_bib0115","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1016\/j.jcrs.2010.06.056","article-title":"Biomechanical parameters of the cornea after collagen crosslinking measured by waveform analysis","volume":"36","author":"Sedaghat","year":"2010","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0120","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3928\/1081597X-20110106-01","article-title":"Detection of biomechanical changes after corneal cross-linking using Ocular Response Analyzer software","volume":"27","author":"Spoerl","year":"2011","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0125","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1136\/bjophthalmol-2017-311627","article-title":"Biomechanical assessment of healthy and keratoconic corneas (with\/without crosslinking) using dynamic ultrahigh-speed Scheimpflug technology and the relevance of the parameter (A1L-A2L)","volume":"103","author":"Fuchsluger","year":"2019","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0130","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jbiomech.2019.06.011","article-title":"Two-year changes in corneal stiffness parameters after accelerated corneal cross-linking","volume":"93","author":"Hashemi","year":"2019","journal-title":"J Biomech"},{"key":"10.1016\/j.jfo.2020.07.002_bib0135","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1001\/jamaophthalmol.2014.3029","article-title":"Increased corneal hysteresis after corneal collagen crosslinking: a study based on applanation resonance technology","volume":"132","author":"Beckman Rehnman","year":"2014","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0140","doi-asserted-by":"crossref","first-page":"016005","DOI":"10.1117\/1.3526701","article-title":"Method for optical coherence elastography of the cornea","volume":"16","author":"Ford","year":"2011","journal-title":"J Biomed Opt"},{"key":"10.1016\/j.jfo.2020.07.002_bib0145","doi-asserted-by":"crossref","first-page":"9197","DOI":"10.1364\/OE.20.009197","article-title":"In vivo Brillouin optical microscopy of the human eye","volume":"20","author":"Scarcelli","year":"2012","journal-title":"Opt Express"},{"key":"10.1016\/j.jfo.2020.07.002_bib0150","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1167\/iovs.12-11387","article-title":"Brillouin microscopy of collagen crosslinking: noncontact depth-dependent analysis of corneal elastic modulus","volume":"54","author":"Scarcelli","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0155","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ajo.2019.02.010","article-title":"Brillouin spectroscopy of normal and keratoconus corneas","volume":"202","author":"Seiler","year":"2019","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0160","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.jcrs.2008.11.036","article-title":"Biomechanical and histological changes after corneal crosslinking with and without epithelial debridement","volume":"35","author":"Wollensak","year":"2009","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0165","doi-asserted-by":"crossref","first-page":"7601","DOI":"10.1167\/iovs.14-15662","article-title":"Optical coherence tomography and confocal microscopy following three different protocols of corneal collagen-crosslinking in keratoconus","volume":"55","author":"Bouheraoua","year":"2014","journal-title":"Investig Ophthalmol Visual Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0170","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1001\/jamaophthalmol.2015.4518","article-title":"Corneal nerve regeneration after collagen cross-linking treatment of keratoconus: A","volume":"134","author":"Parissi","year":"2016","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0175","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1007\/s10792-015-0054-x","article-title":"Collagen cross-linking in keratoconus in Asian eyes: visual, refractive and confocal microscopy outcomes in a prospective randomized controlled trial","volume":"35","author":"Sharma","year":"2015","journal-title":"Int Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0180","doi-asserted-by":"crossref","first-page":"783","DOI":"10.2147\/OPTH.S156500","article-title":"Comparative analysis of safety and efficacy of photorefractive keratectomy versus photorefractive keratectomy combined with crosslinking","volume":"12","author":"Sachdev","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0185","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1016\/j.ophtha.2013.05.027","article-title":"Fourier-domain optical coherence tomography imaging in keratoconus: a corneal structural classification","volume":"120","author":"Sandali","year":"2013","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2020.07.002_bib0190","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jcrs.2018.09.024","article-title":"Contribution of Fourier-domain optical coherence tomography to the diagnosis of keratoconus progression","volume":"45","author":"Ouanezar","year":"2019","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0195","doi-asserted-by":"crossref","first-page":"e201900126","DOI":"10.1002\/jbio.201900126","article-title":"Bowman's topography for improved detection of early ectasia","volume":"12","author":"Chandapura","year":"2019","journal-title":"J Biophotonics"},{"key":"10.1016\/j.jfo.2020.07.002_bib0200","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jcrs.2018.02.017","article-title":"Corneal stromal demarcation line after 4 protocols of corneal crosslinking in keratoconus determined with anterior segment optical coherence tomography","volume":"44","author":"Spadea","year":"2018","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0205","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.2147\/OPTH.S206103","article-title":"Correlation between corneal stromal demarcation line depth and topographic outcomes after two pulsed-light-accelerated crosslinking protocols","volume":"13","author":"Hernandez-Camarena","year":"2019","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0210","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2147\/OPTH.S27170","article-title":"Long term results of a prospective randomized bilateral eye comparison trial of higher fluence, shorter duration ultraviolet A radiation, and riboflavin collagen cross linking for progressive keratoconus","volume":"6","author":"Kanellopoulos","year":"2012","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0215","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.1167\/iovs.13-13748","article-title":"Corneal biomechanical properties at different corneal cross-linking (CXL) irradiances","volume":"55","author":"Hammer","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0220","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.jcrs.2013.10.029","article-title":"Corneal stroma demarcation line after standard and high-intensity collagen crosslinking determined with anterior segment optical coherence tomography","volume":"40","author":"Kymionis","year":"2014","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0225","doi-asserted-by":"crossref","first-page":"3920","DOI":"10.1167\/iovs.18-24656","article-title":"Comparison of standard versus accelerated corneal collagen cross-linking for keratoconus: a meta-analysis","volume":"59","author":"Wen","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0230","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1167\/iovs.12-11409","article-title":"The efficacy of corneal cross-linking shows a sudden decrease with very high intensity UV light and short treatment time","volume":"54","author":"Wernli","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0235","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1167\/tvst.2.7.6","article-title":"The biomechanical effect of corneal collagen cross-linking (CXL) with riboflavin and UV-A is oxygen dependent","volume":"2","author":"Richoz","year":"2013","journal-title":"Transl Vision Sci Technol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0240","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.exer.2016.10.008","article-title":"Corneal elasticity after oxygen enriched high intensity corneal cross linking assessed using atomic force microscopy","volume":"153","author":"Diakonis","year":"2016","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0245","article-title":"Corneal biomechanical evaluation after conventional corneal crosslinking with oxygen enrichment","author":"Wang","year":"2019","journal-title":"Eye Contact Lens"},{"key":"10.1016\/j.jfo.2020.07.002_bib0250","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1080\/02713683.2019.1669663","article-title":"Optimization of oxygen dynamics, UV-A delivery, and drug formulation for accelerated epi-on corneal crosslinking","volume":"45","author":"Hill","year":"2020","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0255","doi-asserted-by":"crossref","first-page":"438","DOI":"10.3928\/1081597X-20180515-02","article-title":"Enhanced-fluence pulsed-light iontophoresis corneal cross-linking: 1-year morphological and clinical results","volume":"34","author":"Mazzotta","year":"2018","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0260","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.3109\/02713683.2015.1101141","article-title":"Analysis of riboflavin compounds in the rabbit cornea in vivo","volume":"41","author":"Hammer","year":"2016","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0265","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.jcrs.2009.01.009","article-title":"Corneal crosslinking: riboflavin concentration in corneal stroma exposed with and without epithelium","volume":"35","author":"Baiocchi","year":"2009","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0270","doi-asserted-by":"crossref","first-page":"771","DOI":"10.3928\/1081597X-20090813-03","article-title":"Effect of epithelial retention and removal on riboflavin absorption in porcine corneas","volume":"25","author":"Samaras","year":"2009","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0275","doi-asserted-by":"crossref","first-page":"715","DOI":"10.3109\/02713683.2010.481068","article-title":"Pharmacological modification of the epithelial permeability by benzalkonium chloride in UVA\/Riboflavin corneal collagen cross-linking","volume":"35","author":"Kissner","year":"2010","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0280","doi-asserted-by":"crossref","first-page":"942","DOI":"10.3928\/1081597X-20100212-09","article-title":"Transepithelial corneal collagen cross-linking in keratoconus","volume":"26","author":"Leccisotti","year":"2010","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0285","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.jcrs.2013.03.026","article-title":"Transepithelial corneal collagen crosslinking for progressive keratoconus","volume":"39","author":"Caporossi","year":"2013","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2015.02.005","article-title":"Transepithelial versus epithelium-off corneal cross-linking for the treatment of progressive keratoconus: a randomized controlled trial","volume":"159","author":"Soeters","year":"2015","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0295","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.jcrs.2012.01.024","article-title":"Refractive and topographic results of benzalkonium chloride-assisted transepithelial crosslinking","volume":"38","author":"Koppen","year":"2012","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0300","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1167\/iovs.13-12595","article-title":"Iontophoresis transcorneal delivery technique for transepithelial corneal collagen crosslinking with riboflavin in a rabbit model","volume":"57","author":"Cassagne","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0305","doi-asserted-by":"crossref","first-page":"746","DOI":"10.3928\/1081597X-20141021-06","article-title":"Transepithelial iontophoresis corneal collagen cross-linking for progressive keratoconus: initial clinical outcomes","volume":"30","author":"Vinciguerra","year":"2014","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0310","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.ophtha.2017.01.040","article-title":"Randomized controlled trial comparing transepithelial corneal cross-linking using iontophoresis with the Dresden protocol in progressive keratoconus","volume":"124","author":"Lombardo","year":"2017","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2020.07.002_bib0315","first-page":"687","article-title":"Efficacy of iontophoresis-assisted epithelium-on corneal cross-linking for keratoconus","volume":"11","author":"Jia","year":"2018","journal-title":"Int J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0320","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1097\/ICO.0000000000001062","article-title":"Conventional and iontophoresis corneal cross-linking for keratoconus: efficacy and assessment by optical coherence tomography and confocal microscopy","volume":"36","author":"Jouve","year":"2017","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0325","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.jcrs.2013.05.022","article-title":"Epithelial-disruption collagen crosslinking for keratoconus: one-year results","volume":"39","author":"Rechichi","year":"2013","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0330","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.3928\/1081597X-20090901-02","article-title":"Collagen cross-linking in early keratoconus with riboflavin in a femtosecond laser-created pocket: initial clinical results","volume":"25","author":"Kanellopoulos","year":"2009","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0335","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/ICO.0000000000000059","article-title":"Biomechanical efficacy of collagen crosslinking in porcine cornea using a femtosecond laser pocket","volume":"33","author":"Wollensak","year":"2014","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0340","doi-asserted-by":"crossref","first-page":"5006","DOI":"10.1167\/iovs.15-16903","article-title":"Transepithelial riboflavin absorption in an ex vivo rabbit corneal model","volume":"56","author":"Gore","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0345","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jcrs.2018.01.010","article-title":"Quantitative analysis of corneal stromal riboflavin concentration without epithelial removal","volume":"44","author":"Rubinfeld","year":"2018","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0350","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/ICO.0000000000000699","article-title":"Transepithelial corneal cross-linking with vitamin E-enhanced riboflavin solution and abbreviated, low-dose UV-A: 24-month clinical outcomes","volume":"35","author":"Caruso","year":"2016","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0355","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/j.jcrs.2018.07.029","article-title":"Corneal crosslinking without epithelial removal","volume":"44","author":"Stulting","year":"2018","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0360","doi-asserted-by":"crossref","first-page":"e66408","DOI":"10.1371\/journal.pone.0066408","article-title":"Corneal absorption of a new riboflavin-nanostructured system for transepithelial collagen cross-linking","volume":"8","author":"Bottos","year":"2013","journal-title":"PLOS One"},{"key":"10.1016\/j.jfo.2020.07.002_bib0365","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.jcrs.2017.03.026","article-title":"Assessment of stromal riboflavin concentration-depth profile in nanotechnology-based transepithelial corneal crosslinking","volume":"43","author":"Lombardo","year":"2017","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0370","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1167\/iovs.16-20813","article-title":"Biomechanical strengthening of the human cornea induced by nanoplatform-based transepithelial riboflavin\/UV-A corneal cross-linking","volume":"58","author":"Labate","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0375","doi-asserted-by":"crossref","first-page":"9174","DOI":"10.1167\/iovs.11-7395","article-title":"Patient-specific computational modeling of keratoconus progression and differential responses to collagen cross-linking","volume":"52","author":"Sinha Roy","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0380","doi-asserted-by":"crossref","first-page":"290","DOI":"10.3928\/1081597X-20170201-02","article-title":"Customized topography-guided corneal collagen cross-linking for keratoconus","volume":"33","author":"Cassagne","year":"2017","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0385","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3928\/1081597X-20161219-03","article-title":"CXL at the slit lamp: no clinically relevant changes in corneal riboflavin distribution during upright UV irradiation","volume":"33","author":"Salmon","year":"2017","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0390","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1167\/iovs.61.3.28","article-title":"Corneal collagen ordering after in vivo rose bengal and riboflavin cross-linking","volume":"61","author":"Germann","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0395","doi-asserted-by":"crossref","first-page":"3426","DOI":"10.1167\/iovs.12-11509","article-title":"Collagen cross-linking using rose bengal and green light to increase corneal stiffness","volume":"54","author":"Cherfan","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0400","doi-asserted-by":"crossref","first-page":"4089","DOI":"10.1167\/iovs.17-22108","article-title":"Long-term biomechanical and histologic results of WST-D\/NIR corneal stiffening in rabbits, up to 8 months follow-up","volume":"58","author":"Brekelmans","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0405","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3928\/1081597X-20160428-08","article-title":"Ex vivo transepithelial collagen cross-linking in porcine and human corneas using human decorin core protein","volume":"32","author":"Metzler","year":"2016","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0410","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1167\/iovs.09-3937","article-title":"Aliphatic beta-nitroalcohols for therapeutic corneoscleral cross-linking: chemical mechanisms and higher order nitroalcohols","volume":"51","author":"Paik","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0415","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.jcrs.2016.04.025","article-title":"Effects of genipin corneal crosslinking in rabbit corneas","volume":"42","author":"Avila","year":"2016","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0420","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1159\/000074071","article-title":"Corneal endothelial cytotoxicity of riboflavin\/UVA treatment in vitro","volume":"35","author":"Wollensak","year":"2003","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0425","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.jcrs.2008.10.060","article-title":"Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas","volume":"35","author":"Hafezi","year":"2009","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0430","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.jcrs.2013.03.021","article-title":"Pachymetry changes during corneal crosslinking: effect of closed eyelids and hypotonic riboflavin solution","volume":"39","author":"Schmidinger","year":"2013","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0435","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/ICO.0000000000000701","article-title":"Accelerated corneal cross-linking with a hypoosmolar riboflavin solution in keratoconic thin corneas: short-term results","volume":"35","author":"Koc","year":"2016","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0440","doi-asserted-by":"crossref","first-page":"366","DOI":"10.3928\/1081597X-20140523-01","article-title":"Contact lens-assisted collagen cross-linking (CACXL): a new technique for cross-linking thin corneas","volume":"30","author":"Jacob","year":"2014","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0445","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s40662-015-0025-3","article-title":"Corneal collagen cross-linking (CXL) in thin corneas","volume":"2","author":"Chen","year":"2015","journal-title":"Eye Vis (Lond)"},{"key":"10.1016\/j.jfo.2020.07.002_bib0450","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.jcrs.2015.04.007","article-title":"Tailored stromal expansion with a refractive lenticule for crosslinking the ultrathin cornea","volume":"41","author":"Sachdev","year":"2015","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0455","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.jcrs.2011.10.027","article-title":"Reliability and repeatability of swept-source Fourier-domain optical coherence tomography and Scheimpflug imaging in keratoconus","volume":"38","author":"Szalai","year":"2012","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0460","first-page":"CD010621","article-title":"Corneal collagen cross-linking for treating keratoconus","volume":"24","author":"Sykakis","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jfo.2020.07.002_bib0465","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1136\/bjo.2010.196493","article-title":"A randomised, prospective study to investigate the efficacy of riboflavin\/ultraviolet A (370nm) corneal collagen cross-linkage to halt the progression of keratoconus","volume":"95","author":"O\u2019Brart","year":"2011","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0470","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jcrs.2010.07.030","article-title":"Corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results","volume":"37","author":"Hersh","year":"2011","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0475","first-page":"S720","article-title":"A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: preliminary results","volume":"24","author":"Wittig-Silva","year":"2008","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0480","doi-asserted-by":"crossref","first-page":"551","DOI":"10.3928\/1081597X-20180702-01","article-title":"Early epithelial remodeling after standard and iontophoresis-assisted corneal cross-linking as evaluated by spectral-domain optical coherence tomography","volume":"34","author":"Atia","year":"2018","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0485","doi-asserted-by":"crossref","first-page":"753","DOI":"10.3928\/1081597X-20121011-01","article-title":"Progression of keratoconus and efficacy of pediatric corneal collagen cross-linking in children and adolescents","volume":"28","author":"Chatzis","year":"2012","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0490","doi-asserted-by":"crossref","first-page":"181","DOI":"10.2174\/1874364101812010181","article-title":"A review of corneal collagen cross-linking\u00a0\u2014\u00a0Current trends in practice applications","volume":"12","author":"Lim","year":"2018","journal-title":"Open Ophthalmol J"},{"key":"10.1016\/j.jfo.2020.07.002_bib0495","doi-asserted-by":"crossref","first-page":"454","DOI":"10.3928\/1081597X-20140527-03","article-title":"Corneal cross-linking for treatment of progressive keratoconus in various age groups","volume":"30","author":"Soeters","year":"2014","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0500","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1097\/ICO.0000000000000819","article-title":"Corneal cross-linking for pediatric keratoconus: long-term results","volume":"35","author":"Godefrooij","year":"2016","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0505","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1007\/s10792-018-0898-y","article-title":"Prospective, randomized contralateral eye study of accelerated and conventional corneal cross-linking in pediatric keratoconus","volume":"39","author":"Eissa","year":"2019","journal-title":"Int Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0510","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.jcrs.2007.12.039","article-title":"Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: long-term results","volume":"34","author":"Raiskup-Wolf","year":"2008","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0515","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jcrs.2014.09.033","article-title":"Corneal collagen crosslinking with riboflavin and ultraviolet-A light in progressive keratoconus: ten-year results","volume":"41","author":"Raiskup","year":"2015","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0520","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jtos.2014.05.002","article-title":"Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis","volume":"12","author":"Craig","year":"2014","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jfo.2020.07.002_bib0525","doi-asserted-by":"crossref","first-page":"e0127079","DOI":"10.1371\/journal.pone.0127079","article-title":"Efficacy of corneal collagen cross-linking for treatment of keratoconus: a meta-analysis of randomized controlled trials","volume":"10","author":"Li","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jfo.2020.07.002_bib0530","doi-asserted-by":"crossref","first-page":"33","DOI":"10.4103\/0974-620X.48420","article-title":"Collagen cross-linking with riboflavin and ultraviolet-A light in keratoconus: one-year results","volume":"2","author":"Arbelaez","year":"2009","journal-title":"Oman J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0535","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1136\/bjophthalmol-2012-302556","article-title":"Long-term follow-up of riboflavin\/ultraviolet A (370nm) corneal collagen cross-linking to halt the progression of keratoconus","volume":"97","author":"O\u2019Brart","year":"2013","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0540","doi-asserted-by":"crossref","first-page":"5652","DOI":"10.1038\/srep05652","article-title":"Corneal collagen cross-linking in keratoconus: a systematic review and meta-analysis","volume":"4","author":"Chunyu","year":"2014","journal-title":"Sci Rep"},{"key":"10.1016\/j.jfo.2020.07.002_bib0545","doi-asserted-by":"crossref","first-page":"8145651","DOI":"10.1155\/2017\/8145651","article-title":"Corneal collagen cross-linking for keratoconus: systematic review","volume":"2017","author":"Kobashi","year":"2017","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.jfo.2020.07.002_bib0550","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.1111\/aos.13814","article-title":"Comparison of standard and accelerated corneal cross-linking for the treatment of keratoconus: a meta-analysis","volume":"97","author":"Shajari","year":"2019","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0555","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1097\/ICO.0000000000000408","article-title":"Global consensus on keratoconus and ectatic diseases","volume":"34","author":"Gomes","year":"2015","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0560","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/eye.2014.230","article-title":"Safety and efficacy of epithelium removal and transepithelial corneal collagen crosslinking for keratoconus","volume":"29","author":"Shalchi","year":"2015","journal-title":"Eye"},{"key":"10.1016\/j.jfo.2020.07.002_bib0565","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3928\/1081597X-20161006-02","article-title":"Repeated cross-linking after a short time does not provide any additional biomechanical stiffness in the mouse cornea in vivo","volume":"33","author":"Tabibian","year":"2017","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0570","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1167\/iovs.13-13042","article-title":"Biomechanical changes after repeated collagen cross-linking on human corneas assessed in vitro using scanning acoustic microscopy","volume":"55","author":"Beshtawi","year":"2014","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0575","doi-asserted-by":"crossref","first-page":"690961","DOI":"10.1155\/2015\/690961","article-title":"Rate of corneal collagen crosslinking redo in private practice: risk factors and safety","volume":"2015","author":"Antoun","year":"2015","journal-title":"J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0580","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1097\/ICO.0000000000002128","article-title":"Clinical results of repeated corneal collagen cross-linking in progressive keratoconus","volume":"39","author":"Akkaya Turhan","year":"2020","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0585","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.jfo.2018.11.015","article-title":"Sterile keratitis following standard corneal collagen crosslinking: a case series and literature review","volume":"42","author":"Mereaux","year":"2019","journal-title":"J Fr Ophtalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0590","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/ICO.0000000000002168","article-title":"The independent effect of various cross-linking treatment modalities on treatment effectiveness in keratoconus","volume":"39","author":"Godefrooij","year":"2020","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0595","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3928\/1081597X-20130129-08","article-title":"SD-OCT analysis of regional epithelial thickness profiles in keratoconus, postoperative corneal ectasia, and normal eyes","volume":"29","author":"Rocha","year":"2013","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0600","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1016\/j.ophtha.2012.03.038","article-title":"Combined transepithelial phototherapeutic keratectomy and corneal collagen cross-linking for progressive keratoconus","volume":"119","author":"Kymionis","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2020.07.002_bib0605","doi-asserted-by":"crossref","first-page":"S807","DOI":"10.3928\/1081597X-20090813-09","article-title":"Simultaneous topography-guided PRK followed by corneal collagen cross-linking for keratoconus","volume":"25","author":"Kymionis","year":"2009","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0610","doi-asserted-by":"crossref","first-page":"272","DOI":"10.3928\/1081597X-20140320-06","article-title":"Simultaneous conventional photorefractive keratectomy and corneal collagen cross-linking for pellucid marginal corneal degeneration","volume":"30","author":"Kymionis","year":"2014","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0615","doi-asserted-by":"crossref","first-page":"S812","DOI":"10.3928\/1081597X-20090813-10","article-title":"Comparison of sequential vs same-day simultaneous collagen cross-linking and topography-guided PRK for treatment of keratoconus","volume":"25","author":"Kanellopoulos","year":"2009","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0620","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.18240\/ijo.2019.12.16","article-title":"Combined corneal CXL and photorefractive keratectomy for treatment of keratoconus: a review","volume":"12","author":"Al-Mohaimeed","year":"2019","journal-title":"Int J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0625","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.ajo.2006.10.041","article-title":"Long-term follow-up of Intacs in keratoconus","volume":"143","author":"Kymionis","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0630","doi-asserted-by":"crossref","first-page":"737","DOI":"10.3928\/1081597X-20110705-01","article-title":"Cross-linking in progressive keratoconus using an epithelial debridement or intrastromal pocket technique after previous corneal ring segment implantation","volume":"27","author":"Alio","year":"2011","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0635","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/j.jcrs.2013.03.022","article-title":"Efficacy of single or paired intrastromal corneal ring segment implantation combined with collagen crosslinking in keratoconus","volume":"39","author":"Yeung","year":"2013","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0640","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.ajo.2014.02.011","article-title":"Same-day intrastromal corneal ring segment and collagen cross-linking for ectasia after laser in situ keratomileusis: long-term results","volume":"157","author":"Yildirim","year":"2014","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0645","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/j.jcrs.0000000000000049","article-title":"Comparison of accelerated CXL alone, accelerated CXL-ICRS, and accelerated","volume":"46","author":"Singal","year":"2020","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0650","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.joco.2017.02.008","article-title":"A review and meta-analysis of corneal cross-linking for post-laser vision correction ectasia","volume":"29","author":"Wan","year":"2017","journal-title":"J Curr Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0655","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1080\/02713683.2019.1656749","article-title":"Review of laser vision correction (LASIK, PRK and SMILE) with simultaneous accelerated corneal crosslinking\u2013long-term results","volume":"44","author":"Lim","year":"2019","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0660","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.jcrs.2017.03.036","article-title":"Photorefractive intrastromal corneal crosslinking for the treatment of myopic refractive errors: Six-month interim findings","volume":"43","author":"Elling","year":"2017","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0665","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1097\/j.jcrs.0000000000000073","article-title":"Photorefractive intrastromal corneal crosslinking for treatment of low myopia: clinical outcomes using the transepithelial approach with supplemental oxygen","volume":"46","author":"Sachdev","year":"2020","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0670","doi-asserted-by":"crossref","first-page":"3402","DOI":"10.1167\/iovs.07-1592","article-title":"Antimicrobial efficacy of riboflavin\/UVA combination (365nm) in vitro for bacterial and fungal isolates: a potential new treatment for infectious keratitis","volume":"49","author":"Martins","year":"2008","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0675","doi-asserted-by":"crossref","first-page":"3950","DOI":"10.1167\/iovs.09-4013","article-title":"In vitro efficacy of antifungal treatment using riboflavin\/UV-A (365nm) combination and amphotericin B","volume":"51","author":"Sauer","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0680","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1097\/ICO.0b013e318169d698","article-title":"Ultraviolet A\/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts","volume":"27","author":"Iseli","year":"2008","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0685","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1097\/ICO.0b013e31819c4e43","article-title":"Riboflavin and ultraviolet a collagen crosslinking of the cornea for the treatment of keratitis","volume":"29","author":"Moren","year":"2010","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0690","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1097\/ICO.0b013e3181d2de91","article-title":"Infectious keratitis treated with corneal crosslinking","volume":"29","author":"Makdoumi","year":"2010","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0695","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1097\/ICO.0b013e31823f8f48","article-title":"Photo-activated riboflavin therapy of refractory corneal ulcers","volume":"31","author":"Panda","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0700","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1136\/bjophthalmol-2014-304944","article-title":"Collagen crosslinking in the management of advanced non-resolving microbial keratitis","volume":"98","author":"Shetty","year":"2014","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0705","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/j.ophtha.2014.01.011","article-title":"Collagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting","volume":"121","author":"Said","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2020.07.002_bib0710","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/ICO.0000000000000375","article-title":"Ultraviolet A\/riboflavin collagen cross-linking for treatment of moderate bacterial corneal ulcers","volume":"34","author":"Bamdad","year":"2015","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0715","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00417-011-1754-1","article-title":"UVA-riboflavin photochemical therapy of bacterial keratitis: a pilot study","volume":"250","author":"Makdoumi","year":"2012","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0720","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.ophtha.2010.06.041","article-title":"Riboflavin and ultraviolet light a therapy as an adjuvant treatment for medically refractive Acanthamoeba keratitis: report of 3 cases","volume":"118","author":"Khan","year":"2011","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2020.07.002_bib0725","doi-asserted-by":"crossref","first-page":"103","DOI":"10.5935\/0004-2749.20190018","article-title":"Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis","volume":"82","author":"Cristian","year":"2019","journal-title":"Arq Bras Oftalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0730","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1080\/02713683.2018.1501074","article-title":"Effect of riboflavin\/rose bengal-mediated PACK-CXL on Acanthamoeba trophozoites and cysts in vitro","volume":"43","author":"Atalay","year":"2018","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0735","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.ajo.2011.07.025","article-title":"Evaluation of in vitro efficacy of combined riboflavin and ultraviolet a for Acanthamoeba isolates","volume":"153","author":"del Buey","year":"2012","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0740","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1016\/j.jcrs.2007.06.036","article-title":"Herpetic keratitis with iritis after corneal crosslinking with riboflavin and ultraviolet A for keratoconus","volume":"33","author":"Kymionis","year":"2007","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0745","doi-asserted-by":"crossref","first-page":"706","DOI":"10.3928\/1081597X-20120921-06","article-title":"Photoactivated riboflavin treatment of infectious keratitis using collagen cross-linking technology","volume":"28","author":"Price","year":"2012","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0750","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.jtos.2019.08.006","article-title":"Photoactivated chromophore for infectious keratitis\u00a0\u2014\u00a0Corneal cross-linking (PACK-CXL): a systematic review and meta-analysis","volume":"17","author":"Ting","year":"2019","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jfo.2020.07.002_bib0755","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1111\/j.1600-0420.2007.01085.x","article-title":"Riboflavin-ultraviolet light induced cross-linking in endothelial decompensation","volume":"86","author":"Ehlers","year":"2008","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0760","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1159\/000187630","article-title":"Potential use of riboflavin\/UVA cross-linking in bullous keratopathy","volume":"41","author":"Wollensak","year":"2009","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.jfo.2020.07.002_bib0765","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jcrs.2009.07.041","article-title":"Collagen crosslinking with riboflavin and ultraviolet-A in eyes with pseudophakic bullous keratopathy","volume":"36","author":"Ghanem","year":"2010","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0770","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/ICO.0000000000000004","article-title":"Outcomes of corneal collagen crosslinking in pseudophakic bullous keratopathy","volume":"33","author":"Sharma","year":"2014","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0775","first-page":"291","article-title":"Sustainability of pain relief after corneal collagen cross-linking in eyes with bullous keratopathy","volume":"7","author":"Ono","year":"2018","journal-title":"Asia Pac J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0780","first-page":"965","article-title":"Corneal collagen cross linking (CXL) in treatment of Pseudophakic Bullous Keratopathy","volume":"32","author":"Khan","year":"2016","journal-title":"Pak J Med Sci"},{"key":"10.1016\/j.jfo.2020.07.002_bib0785","first-page":"1","article-title":"Accelerated, pulsed collagen cross-linking versus the Dresden protocol in keratoconus: a case series","volume":"4","author":"Dervenis","year":"2020","journal-title":"Med Princ Pract."},{"key":"10.1016\/j.jfo.2020.07.002_bib0790","doi-asserted-by":"crossref","DOI":"10.1016\/j.clae.2020.03.004","article-title":"Prospective two year study of changes in corneal density following transepithelial pulsed, epithelium-off continuous and epithelium-off pulsed, corneal crosslinking for keratoconus","author":"Ziaei","year":"2020","journal-title":"Cont Lens Anterior Eye"},{"key":"10.1016\/j.jfo.2020.07.002_bib0795","doi-asserted-by":"crossref","first-page":"7487186","DOI":"10.1155\/2020\/7487186","article-title":"Safety, efficacy, and predictive factors of conventional epithelium-off corneal crosslinking in the treatment of progressive keratoconus","volume":"2020","author":"Farhat","year":"2020","journal-title":"J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0800","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ajo.2020.01.006","article-title":"Accelerated corneal cross-linking: efficacy, risk of progression, and characteristics affecting outcomes. A large, single-center prospective study","volume":"213","author":"Hatch","year":"2020","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0805","doi-asserted-by":"crossref","first-page":"8285649","DOI":"10.1155\/2019\/8285649","article-title":"10-year results of standard cross-linking in patients with progressive keratoconus in Romania","volume":"2019","author":"Nicula","year":"2019","journal-title":"J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0810","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.jcrs.2019.01.026","article-title":"Two-year outcomes of a randomized controlled trial of transepithelial corneal crosslinking with iontophoresis for keratoconus","volume":"45","author":"Lombardo","year":"2019","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0815","first-page":"219","article-title":"Clinical and microstructural changes with different iontophoresis-assisted corneal cross-linking methods for keratoconus","volume":"12","author":"Liao","year":"2019","journal-title":"Int J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0820","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jcrs.2017.12.022","article-title":"Transepithelial corneal crosslinking for keratoconus","volume":"44","author":"Hersh","year":"2018","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0825","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1097\/ICO.0000000000001736","article-title":"Keratoconus progression after corneal cross-linking in eyes with preoperative maximum keratometry values of 58 diopters and steeper","volume":"37","author":"Kuechler","year":"2018","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0830","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1186\/s12886-018-0999-4","article-title":"Two-year topographic and densitometric outcomes of accelerated (45 mW\/cm2) transepithelial corneal cross-linking for keratoconus: a case-control study","volume":"18","author":"Huang","year":"2018","journal-title":"BMC Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0835","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.jcrs.2017.05.036","article-title":"Efficacy of different accelerated corneal crosslinking protocols for progressive keratoconus","volume":"43","author":"Toker","year":"2017","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0840","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.ophtha.2017.05.036","article-title":"U.S. multicenter clinical trial of corneal collagen crosslinking for treatment of corneal ectasia after refractive surgery","volume":"124","author":"Hersh","year":"2017","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2020.07.002_bib0845","doi-asserted-by":"crossref","first-page":"e649","DOI":"10.1111\/aos.13538","article-title":"Iontophoretic collagen cross-linking versus epithelium-off collagen cross-linking for early stage of progressive keratoconus\u20133 years follow-up study","volume":"95","author":"Cantemir","year":"2017","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0850","doi-asserted-by":"crossref","first-page":"e600","DOI":"10.1111\/aos.13032","article-title":"Standard corneal collagen crosslinking versus transepithelial iontophoresis-assisted corneal crosslinking, 24 months follow-up: randomized control trial","volume":"94","author":"Bikbova","year":"2016","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0855","doi-asserted-by":"crossref","first-page":"340","DOI":"10.4103\/0974-9233.159755","article-title":"Corneal collagen cross-linking in the treatment of progressive keratoconus: a randomized controlled contralateral eye study","volume":"22","author":"Seyedian","year":"2015","journal-title":"Middle East Afr J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0860","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2015.06.027","article-title":"Corneal collagen cross-linking for the treatment of progressive corneal ectasia","volume":"160","author":"Poli","year":"2015","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0865","doi-asserted-by":"crossref","DOI":"10.1136\/bjophthalmol-2019-315260","article-title":"Three-year follow-up of accelerated transepithelial corneal cross-linking for progressive paediatric keratoconus","author":"Tian","year":"2020","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0870","doi-asserted-by":"crossref","first-page":"e352","DOI":"10.1111\/aos.14275","article-title":"Standard cross-linking protocol versus accelerated and transepithelial cross-linking protocols for treatment of paediatric keratoconus: a 2-year comparative study","volume":"98","author":"Iqbal","year":"2020","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0875","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/j.jcrs.0000000000000101","article-title":"Accelerated corneal crosslinking in children with keratoconus: 5-year results and comparison of 2 protocols","volume":"46","author":"Agca","year":"2020","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0880","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3928\/1081597X-20200302-01","article-title":"Efficacy of conventional versus accelerated corneal cross-linking in pediatric keratoconus: two-year outcomes","volume":"36","author":"Turhan","year":"2020","journal-title":"J Refract Surg"},{"key":"10.1016\/j.jfo.2020.07.002_bib0885","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.2147\/TCRM.S224533","article-title":"Comparative results between \u201cEpi-Off\u201d conventional and accelerated corneal collagen crosslinking for progressive keratoconus in pediatric patients","volume":"15","author":"Nicula","year":"2019","journal-title":"Ther Clin Risk Manag"},{"key":"10.1016\/j.jfo.2020.07.002_bib0890","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1097\/ICO.0000000000001965","article-title":"Iontophoretic transepithelial collagen cross-linking versus epithelium-off collagen cross-linking in pediatric patients: 3-year follow-up","volume":"38","author":"Buzzonetti","year":"2019","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0895","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/ICO.0000000000001505","article-title":"Corneal collagen cross-linking with riboflavin and ultraviolet a light for pediatric keratoconus: ten-year results","volume":"37","author":"Mazzotta","year":"2018","journal-title":"Cornea"},{"key":"10.1016\/j.jfo.2020.07.002_bib0900","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.clae.2018.06.001","article-title":"Accelerated versus standard corneal collagen cross-linking in pediatric keratoconus patients: 24 months follow-up results","volume":"41","author":"Sarac","year":"2018","journal-title":"Contact Lens Anterior Eye"},{"key":"10.1016\/j.jfo.2020.07.002_bib0905","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1177\/1120672118760149","article-title":"Long-term efficacy and safety after corneal collagen crosslinking in pediatric patients: three-year follow-up","volume":"28","author":"Henriquez","year":"2018","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.jfo.2020.07.002_bib0910","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1097\/ICO.0000000000001366","article-title":"Accelerated epi-on versus standard epi-off corneal collagen cross-linking for progressive keratoconus in pediatric patients","volume":"36","author":"Henriquez","year":"2017","journal-title":"Cornea"}],"container-title":["Journal Fran\u00e7ais d'Ophtalmologie"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0181551220303971?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0181551220303971?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T19:13:37Z","timestamp":1759259617000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0181551220303971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":182,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S0181551220303971"],"URL":"https:\/\/doi.org\/10.1016\/j.jfo.2020.07.002","relation":{},"ISSN":["0181-5512"],"issn-type":[{"value":"0181-5512","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Corneal crosslinking in keratoconus management","name":"articletitle","label":"Article Title"},{"value":"Journal Fran\u00e7ais d'Ophtalmologie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jfo.2020.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}