{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:04:39Z","timestamp":1759334679443,"version":"build-2065373602"},"reference-count":49,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,29]],"date-time":"2023-01-29T00:00:00Z","timestamp":1674950400000},"content-version":"am","delay-in-days":362,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal Fran\u00e7ais d'Ophtalmologie"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.jfo.2021.08.012","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T17:37:59Z","timestamp":1640713079000},"page":"173-184","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Facteurs pronostiques des gliomes des voies optiques associ\u00e9s \u00e0 la neurofibromatose de type 1\u00a0chez les enfants"],"prefix":"10.1016","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3944-2805","authenticated-orcid":false,"given":"C.","family":"Florent","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3059-9299","authenticated-orcid":false,"given":"M.","family":"Beylerian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4280-9265","authenticated-orcid":false,"given":"K.","family":"Mairot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2799-7376","authenticated-orcid":false,"given":"L.","family":"Dambricourt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Andr\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7192-1523","authenticated-orcid":false,"given":"T.","family":"David","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8639-9275","authenticated-orcid":false,"given":"N.","family":"Girard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6055-9007","authenticated-orcid":false,"given":"F.","family":"Audic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5101-6289","authenticated-orcid":false,"given":"D.","family":"Denis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jfo.2021.08.012_bib0250","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/oxfordjournals.aje.a010118","article-title":"NF1\u00a0gene and neurofibromatosis 1","volume":"151","author":"Rasmussen","year":"2000","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0255","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1093\/brain\/111.6.1355","article-title":"Von Recklinghausen neurofibromatosis. A clinical and population study in south-east Wales","volume":"111","author":"Huson","year":"1988","journal-title":"Brain"},{"year":"2016","series-title":"Protocole National de Diagnostic et de Soins (PNDS)","author":"Valeyrie-Allanore Lurence","key":"10.1016\/j.jfo.2021.08.012_bib0260"},{"key":"10.1016\/j.jfo.2021.08.012_bib0265","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.survophthal.2017.10.007","article-title":"Ophthalmic manifestations in neurofibromatosis type 1","volume":"63","author":"Kinori","year":"2018","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0270","first-page":"575","article-title":"Neurofibromatosis. Conference statement. National Institutes of Health Consensus Development Conference","volume":"45","year":"1988","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0275","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1001\/archneurpsyc.1958.02340060003001","article-title":"Gliomas of the optic nerves","volume":"79","author":"Dodge","year":"1958","journal-title":"AMA Arch Neurol Psychiatry"},{"key":"10.1016\/j.jfo.2021.08.012_bib0280","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/WNO.0000000000000419","article-title":"Swelling of the optic nerve head: a backstage view of a staging scheme","volume":"37","author":"Fris\u00e9n","year":"2017","journal-title":"J Neuroophthalmol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0285","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s11060-016-2163-4","article-title":"Long-term visual outcomes of optic pathway gliomas in pediatric patients without neurofibromatosis type 1","volume":"129","author":"Wan","year":"2016","journal-title":"J Neurooncol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0290","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1001\/archopht.120.3.268","article-title":"A randomized trial of atropine vs. patching for treatment of moderate amblyopia in children","volume":"120","author":"Group","year":"2002","journal-title":"Arch Ophthalmol"},{"issue":"9234","key":"10.1016\/j.jfo.2021.08.012_bib0295","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/S0140-6736(00)02716-1","article-title":"Frequency of choroidal abnormalities in neurofibromatosis type 1","volume":"356","author":"Yasunari","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.jfo.2021.08.012_bib0300","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S1470-2045(11)70057-2","article-title":"Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas","volume":"12","author":"Van den Bent","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0305","first-page":"11","article-title":"Optic Pathway Glioma in Type 1\u00a0neurofibromatosis: review of its pathogenesis, diagnostic assessment, and treatment recommendations","author":"Cassina","year":"2019","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.jfo.2021.08.012_bib0310","first-page":"929","article-title":"von Recklinghausen neurofibromatosis","volume":"91","author":"Lewis","year":"1984","journal-title":"II. Incidence of optic gliomata. Ophthalmology"},{"key":"10.1016\/j.jfo.2021.08.012_bib0315","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/S0022-3476(89)80137-4","article-title":"Optic gliomas in children with neurofibromatosis type 1","volume":"114","author":"Listernick","year":"1989","journal-title":"J Pediatr"},{"key":"10.1016\/j.jfo.2021.08.012_bib0320","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0022-3476(94)70122-9","article-title":"Natural history of optic pathway tumors in children with neurofibromatosis type 1: a longitudinal study","volume":"125","author":"Listernick","year":"1994","journal-title":"J Pediatr"},{"key":"10.1016\/j.jfo.2021.08.012_bib0325","first-page":"530","article-title":"Neurofibromatosis type 1\u00a0and optic pathway gliomas. A series of 80\u00a0patients","volume":"46","author":"Pascual-Castroviejo","year":"2008","journal-title":"Rev Neurol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0330","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/ana.21107","article-title":"Optic pathway gliomas in neurofibromatosis-1: controversies and recommendations","volume":"61","author":"Listernick","year":"2007","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0335","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpeds.2015.07.001","article-title":"The use of magnetic resonance imaging screening for optic pathway gliomas in children with neurofibromatosis Type 1","volume":"167","author":"Prada","year":"2015","journal-title":"J Pediatr"},{"key":"10.1016\/j.jfo.2021.08.012_bib0340","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jaapos.2009.11.020","article-title":"Optic pathway gliomas in patients with neurofibromatosis type 1: follow-up of 44\u00a0patients","volume":"14","author":"Segal","year":"2010","journal-title":"J AAPOS"},{"key":"10.1016\/j.jfo.2021.08.012_bib0345","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ajo.2020.03.053","article-title":"Neurofibromatosis type 1-associated optic pathway glioma in children: a follow-up of 10\u00a0years or more","volume":"221","author":"Kinori","year":"2020","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0350","first-page":"445","article-title":"Neurofibromatosis type 1\u00a0in children","volume":"93","author":"Beauchamp","year":"1995","journal-title":"Trans Am Ophthalmol Soc"},{"key":"10.1016\/j.jfo.2021.08.012_bib0355","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1212\/01.WNL.0000144341.16830.01","article-title":"Late-onset optic pathway tumors in children with neurofibromatosis 1","volume":"63","author":"Listernick","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jfo.2021.08.012_bib0360","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1159\/000445064","article-title":"Optic pathway gliomas: clinical manifestation, treatment, and follow-up","volume":"51","author":"Ertiaei","year":"2016","journal-title":"Pediatr Neurosurg"},{"key":"10.1016\/j.jfo.2021.08.012_bib0365","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1093\/hmg\/ddw039","article-title":"NF1\u00a0germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1","volume":"25","author":"Toonen","year":"2016","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jfo.2021.08.012_bib0370","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1084\/jem.20160447","article-title":"Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1\u00a0optic glioma-induced retinal pathology","volume":"214","author":"Toonen","year":"2017","journal-title":"J Exp Med"},{"key":"10.1016\/j.jfo.2021.08.012_bib0375","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/ana.24093","article-title":"Sex is a major determinant of neuronal dysfunction in neurofibromatosis type 1","volume":"75","author":"Diggs-Andrews","year":"2014","journal-title":"Ann Neurol"},{"issue":"a","key":"10.1016\/j.jfo.2021.08.012_bib0380","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1002\/ajmg.a.20650","article-title":"Outcomes of systematic screening for optic pathway tumors in children with Neurofibromatosis Type 1","volume":"127","author":"Blazo","year":"2004","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.jfo.2021.08.012_bib0385","doi-asserted-by":"crossref","first-page":"334","DOI":"10.3928\/01913913-20160810-03","article-title":"Optic gliomas in Neurofibromatosis Type 1","volume":"53","author":"Parkhurst","year":"2016","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"10.1016\/j.jfo.2021.08.012_bib0390","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.ejpn.2015.12.002","article-title":"Systematic MRI in NF1\u00a0children under six years of age for the diagnosis of optic pathway gliomas. Study and outcome of a French cohort","volume":"20","author":"Blanchard","year":"2016","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0395","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1056\/NEJMp1414786","article-title":"Anesthetic neurotoxicity--clinical implications of animal models","volume":"372","author":"Rappaport","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jfo.2021.08.012_bib0400","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1586\/ern.09.4","article-title":"Gliomas in patients with neurofibromatosis type 1","volume":"9","author":"Albers","year":"2009","journal-title":"Expert Rev Neurother"},{"key":"10.1016\/j.jfo.2021.08.012_bib0405","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1136\/jmg.2006.045906","article-title":"Guidelines for the diagnosis and management of individuals with neurofibromatosis 1","volume":"44","author":"Ferner","year":"2007","journal-title":"J Med Genet"},{"key":"10.1016\/j.jfo.2021.08.012_bib0410","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1080\/08820530701745223","article-title":"Neurofibromatosis type I: genetics and clinical manifestations","volume":"23","author":"Savar","year":"2008","journal-title":"Semin Ophthalmol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0415","first-page":"1","article-title":"VA. Tumeurs du nerf optique","volume":"4","author":"Vi\u00e9","year":"2019"},{"key":"10.1016\/j.jfo.2021.08.012_bib0420","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1093\/neuonc\/noaa153","article-title":"NF1\u00a0optic pathway glioma: analyzing risk factors for visual outcome and indications to treat","volume":"23","author":"Azizi","year":"2021","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0425","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1056\/NEJM199105023241807","article-title":"Lisch nodules in neurofibromatosis type 1","volume":"324","author":"Lubs","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jfo.2021.08.012_bib0430","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.jaapos.2010.08.014","article-title":"Optical coherence tomography in the evaluation of neurofibromatosis type-1\u00a0subjects with optic pathway gliomas","volume":"14","author":"Chang","year":"2010","journal-title":"J Aapos"},{"key":"10.1016\/j.jfo.2021.08.012_bib0435","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1007\/s10384-014-0308-6","article-title":"Investigation of retinal nerve fiber layer thickness in patients with neurofibromatosis-1","volume":"58","author":"Topcu-Yilmaz","year":"2014","journal-title":"Jpn J Ophthalmol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0440","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2010.08.046","article-title":"Retinal nerve fiber layer thickness in children with optic pathway gliomas","volume":"151","author":"Avery","year":"2011","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0445","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ophtha.2011.07.046","article-title":"Choroidal abnormalities detected by near-infrared reflectance imaging as a new diagnostic criterion for neurofibromatosis 1","volume":"119","author":"Viola","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.jfo.2021.08.012_bib0450","article-title":"Correlation between ophthalmologic and neuroradiologic findings in type 1\u00a0neurofibromatosis","author":"Godinho","year":"2021","journal-title":"J Neuroophthalmol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0455","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3928\/01913913-20180925-02","article-title":"Prevalence of strabismus among children with neurofibromatosis type 1\u00a0disease with and without optic pathway glioma","volume":"56","author":"Dotan","year":"2019","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"10.1016\/j.jfo.2021.08.012_bib0460","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.jaapos.2015.06.003","article-title":"Strabismus in patients with neurofibromatosis type 1-associated optic pathway glioma","volume":"19","author":"Parness-Yossifon","year":"2015","journal-title":"J AAPOS"},{"key":"10.1016\/j.jfo.2021.08.012_bib0465","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1093\/neuonc\/nos076","article-title":"Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis","volume":"14","author":"Fisher","year":"2012","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0470","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/S0002-9394(00)00852-7","article-title":"Visual loss in children with neurofibromatosis type 1\u00a0and optic pathway gliomas: relation to tumor location by magnetic resonance imaging","volume":"131","author":"Balcer","year":"2001","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0475","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1007\/s00381-020-04697-1","article-title":"Neurofibromatosis 1-associated optic pathway gliomas","volume":"36","author":"Shofty","year":"2020","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.jfo.2021.08.012_bib0480","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1002\/pbc.24297","article-title":"Long-term efficacy and toxicity of bevacizumab-based therapy in children with recurrent low-grade gliomas","volume":"60","author":"Hwang","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.jfo.2021.08.012_bib0485","doi-asserted-by":"crossref","first-page":"e630","DOI":"10.1097\/MPH.0000000000002002","article-title":"Metronomic maintenance with weekly vinblastine after induction with bevacizumab-irinotecan in children with low-grade glioma prevents early relapse","volume":"43 (5)","author":"Roux","year":"2021","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.jfo.2021.08.012_bib0245","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/MPH.0000000000002060","article-title":"Vision outcomes for pediatric patients with optic pathway gliomas associated with neurofibromatosis type i: a systematic review of the clinical evidence","volume":"43","author":"Thirunavu","year":"2021","journal-title":"J Pediatr Hematol Oncol"}],"container-title":["Journal Fran\u00e7ais d'Ophtalmologie"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0181551221005908?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0181551221005908?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T19:17:11Z","timestamp":1759259831000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0181551221005908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S0181551221005908"],"URL":"https:\/\/doi.org\/10.1016\/j.jfo.2021.08.012","relation":{},"ISSN":["0181-5512"],"issn-type":[{"type":"print","value":"0181-5512"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Facteurs pronostiques des gliomes des voies optiques associ\u00e9s \u00e0 la neurofibromatose de type 1\u00a0chez les enfants","name":"articletitle","label":"Article Title"},{"value":"Journal Fran\u00e7ais d'Ophtalmologie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jfo.2021.08.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}