{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:44:27Z","timestamp":1791531867194,"version":"4.3.4"},"reference-count":126,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Global Antimicrobial Resistance"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.jgar.2013.01.005","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T15:17:32Z","timestamp":1363879052000},"page":"7-16","source":"Crossref","is-referenced-by-count":87,"title":["Carbapenemases: Partners in crime"],"prefix":"10.1016","volume":"1","author":[{"given":"Karen","family":"Bush","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgar.2013.01.005_bib0005","first-page":"259","article-title":"Monotherapy is appropriate for nosocomial pneumonia in the intensive care unit","volume":"8","author":"Arbo","year":"1993","journal-title":"Seminars in Respiratory Infections"},{"key":"10.1016\/j.jgar.2013.01.005_bib0010","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1517\/13543784.11.4.529","article-title":"Recent developments in carbapenems","volume":"11","author":"Bonfiglio","year":"2002","journal-title":"Expert Opinion on Investigational Drugs"},{"key":"10.1016\/j.jgar.2013.01.005_bib0015","first-page":"929","article-title":"Outpatient parenteral antimicrobial therapy: recent developments and future prospects","volume":"11","author":"Torok","year":"2010","journal-title":"Current Opinion in Investigational Drugs"},{"key":"10.1016\/j.jgar.2013.01.005_bib0020","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jinf.2003.10.001","article-title":"Evaluation of outpatient treatment with ertapenem in a double blind controlled clinical trial of complicated skin\/skin structure infections","volume":"48","author":"Gesser","year":"2004","journal-title":"Journal of Infection"},{"key":"10.1016\/j.jgar.2013.01.005_bib0025","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1093\/jac\/dkr290","article-title":"Longitudinal survey of carbapenem resistance and resistance mechanisms in Enterobacteriaceae and non-fermenters from the USA in 2007\u20132009","volume":"66","author":"Davies","year":"2011","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0030","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.diagmicrobio.2010.12.012","article-title":"Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum \u03b2-lactamase-producing Klebsiella pneumoniae and Escherichia coli","volume":"71","author":"Park","year":"2011","journal-title":"Diagnostic Microbiology and Infectious Disease"},{"key":"10.1016\/j.jgar.2013.01.005_bib0035","doi-asserted-by":"crossref","first-page":"4329","DOI":"10.1128\/AAC.00810-07","article-title":"Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals","volume":"51","author":"Guti\u00e9rrez","year":"2007","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0040","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1128\/AAC.50.5.1633-1641.2006","article-title":"Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates","volume":"50","author":"Quale","year":"2006","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0045","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1128\/CMR.00001-07","article-title":"Carbapenemases: the versatile \u03b2-lactamases","volume":"20","author":"Queenan","year":"2007","journal-title":"Clinical Microbiology Reviews"},{"key":"10.1016\/j.jgar.2013.01.005_bib0050","series-title":"\u03b2-Lactamase classification and amino acid sequences for TEM, SHV and OXA extended-spectrum and inhibitor resistant enzymes","author":"Jacoby","year":"2012"},{"key":"10.1016\/j.jgar.2013.01.005_bib0055","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1038\/nrmicro2693","article-title":"Tackling antibiotic resistance","volume":"9","author":"Bush","year":"2011","journal-title":"Nature Reviews Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0060","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1128\/AAC.48.7.2347-2349.2004","article-title":"Update of the standard numbering scheme for class B \u03b2-lactamases","volume":"48","author":"Garau","year":"2004","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0065","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1128\/AAC.47.12.3881-3889.2003","article-title":"Carbapenem-resistant strain of Klebsiella oxytoca harboring carbapenem-hydrolyzing \u03b2-lactamase KPC-2","volume":"47","author":"Yigit","year":"2003","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0070","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1093\/jac\/dkq048","article-title":"Detection and characterization of class A extended-spectrum-\u03b2-lactamase-producing Pseudomonas aeruginosa isolates in Belgian hospitals","volume":"65","author":"Glupczynski","year":"2010","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2008.09.003","article-title":"Metallo-\u03b2-lactamases in Gram-negative bacteria: introducing the era of pan-resistance?","volume":"33","author":"Maltezou","year":"2009","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.jgar.2013.01.005_bib0080","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1128\/JCM.06852-11","article-title":"MOSAR WP2 and SATURN WP1 Study Teams Current trends in culture-based and molecular detection of extended-spectrum-\u03b2-lactamase-harboring and carbapenem-resistant Enterobacteriaceae","volume":"50","author":"Gazin","year":"2012","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0085","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/SMJ.0b013e3181fd7d5a","article-title":"Emergence of Klebsiella pneumoniae carbapenemase-producing bacteria","volume":"104","author":"Arnold","year":"2011","journal-title":"Southern Medical Journal"},{"key":"10.1016\/j.jgar.2013.01.005_bib0090","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1093\/cid\/cir202","article-title":"Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention","volume":"53","author":"Gupta","year":"2011","journal-title":"Clinical Infectious Diseases"},{"key":"10.1016\/j.jgar.2013.01.005_bib0095","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.tim.2011.09.005","article-title":"The emerging NDM carbapenemases","volume":"19","author":"Nordmann","year":"2011","journal-title":"Trends in Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0100","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.3201\/eid1710.110655","article-title":"Global spread of carbapenemase-producing Enterobacteriaceae","volume":"17","author":"Nordmann","year":"2011","journal-title":"Emerging Infectious Diseases"},{"key":"10.1016\/j.jgar.2013.01.005_bib0105","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1128\/AAC.41.2.223","article-title":"Carbapenem-hydrolyzing \u03b2-lactamases","volume":"41","author":"Rasmussen","year":"1997","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0110","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1128\/AAC.40.9.2080","article-title":"Characterization of IMI-1 \u03b2-lactamase, a class A carbapenem-hydrolyzing enzyme from Enterobacter cloacae","volume":"40","author":"Rasmussen","year":"1996","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0115","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1128\/AAC.44.11.3035-3039.2000","article-title":"SME-type carbapenem-hydrolyzing class A \u03b2-lactamases from geographically diverse Serratia marcescens strains","volume":"44","author":"Queenan","year":"2000","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0120","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1128\/AAC.37.5.939","article-title":"Biochemical properties of a carbapenem-hydrolyzing \u03b2-lactamase from Enterobacter cloacae and cloning of the gene into Escherichia coli","volume":"37","author":"Nordmann","year":"1993","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0125","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1128\/AAC.38.6.1262","article-title":"Cloning and sequence analysis of the gene for a carbapenem-hydrolyzing class A \u03b2-lactamase Sme-1, from Serratia marcescens S6","volume":"38","author":"Naas","year":"1994","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0130","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ijantimicag.2011.09.014","article-title":"Molecular diversity in mechanisms of carbapenem resistance in paediatric Enterobacteriaceae","volume":"39","author":"Little","year":"2012","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.jgar.2013.01.005_bib0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijantimicag.2012.08.008","article-title":"Detection systems for carbapenemase gene identification should include the SME serine carbapenemase","volume":"41","author":"Bush","year":"2013","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.jgar.2013.01.005_bib0140","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1128\/AAC.44.6.1556-1561.2000","article-title":"OXA-24, a novel class D \u03b2-lactamase with carbapenemase activity in an Acinetobacter baumannii clinical strain","volume":"44","author":"Bou","year":"2000","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0145","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3201\/eid1601.090852","article-title":"Worldwide dissemination of the blaOXA-23 carbapenemase gene of Acinetobacter baumannii","volume":"16","author":"Mugnier","year":"2010","journal-title":"Emerging Infectious Diseases"},{"key":"10.1016\/j.jgar.2013.01.005_bib0150","doi-asserted-by":"crossref","first-page":"260","DOI":"10.3201\/eid1102.030684","article-title":"Carbapenemase-producing Enterobacteriaceae, U.S. rivers","volume":"11","author":"Aubron","year":"2005","journal-title":"Emerging Infectious Diseases"},{"key":"10.1016\/j.jgar.2013.01.005_bib0155","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1128\/AAC.00961-09","article-title":"Novel Ambler class A carbapenem-hydrolyzing \u03b2-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France","volume":"54","author":"Girlich","year":"2010","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0160","doi-asserted-by":"crossref","first-page":"4405","DOI":"10.1128\/AAC.00681-11","article-title":"Origin of OXA-181, an emerging carbapenem-hydrolyzing oxacillinase, as a chromosomal gene in Shewanella xiamenensis","volume":"55","author":"Potron","year":"2012","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0165","doi-asserted-by":"crossref","first-page":"11C","DOI":"10.1042\/bj0980011C","article-title":"Zinc as a cofactor for cephalosporinase from Bacillus cereus 569","volume":"98","author":"Sabath","year":"1966","journal-title":"Biochemical Journal"},{"key":"10.1016\/j.jgar.2013.01.005_bib0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7164\/antibiotics.32.1","article-title":"Thienamycin, a new \u03b2-lactam antibiotic I. Discovery, taxonomy, isolation and physical properties","volume":"32","author":"Kahan","year":"1979","journal-title":"Journal of Antibiotics (Tokyo)"},{"key":"10.1016\/j.jgar.2013.01.005_bib0175","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1128\/AAC.34.5.755","article-title":"Biochemical characterization of a \u03b2-lactamase that hydrolyzes penems and carbapenems from two Serratia marcescens isolates","volume":"34","author":"Yang","year":"1990","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0180","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/jac\/37.1.33","article-title":"The \u2018hidden\u2019 carbapenemase of Aeromonas hydrophila","volume":"37","author":"Hayes","year":"1996","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0185","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1128\/AAC.47.6.2040-2042.2003","article-title":"Biochemical characterization of \u03b2-lactamases Bla1 and Bla2 from Bacillus anthracis","volume":"47","author":"Materon","year":"2003","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0190","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1128\/AAC.38.9.2116","article-title":"Contribution of enzymatic properties, cell permeability, and enzyme expression to microbiological activities of \u03b2-lactams in three Bacteroides fragilis isolates that harbor a metallo-\u03b2-lactamase gene","volume":"38","author":"Rasmussen","year":"1994","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0195","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1128\/AAC.22.4.564","article-title":"Purification and properties of inducible penicillin \u03b2-lactamase isolated from Pseudomonas maltophilia","volume":"22","author":"Saino","year":"1982","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0200","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1128\/AAC.25.3.362","article-title":"Purification and properties of an inducible cephalosporinase from Pseudomonas maltophilia GN12873","volume":"25","author":"Saino","year":"1984","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0205","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1128\/AAC.39.6.1211","article-title":"A functional classification scheme for \u03b2-lactamases and its correlation with molecular structure","volume":"39","author":"Bush","year":"1995","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0210","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1146\/annurev-micro-090110-102911","article-title":"Epidemiological expansion, structural studies, and clinical challenges of new \u03b2-lactamases from Gram-negative bacteria","volume":"65","author":"Bush","year":"2011","journal-title":"Annual Review of Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0215","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/j.1875-9114.2012.01035.x","article-title":"Klebsiella pneumoniae carbapenemases in Enterobacteriaceae: history, evolution, and microbiology concerns","volume":"32","author":"Rapp","year":"2012","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0220","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1469-0691.2012.03821.x","article-title":"European Network on Carbapenemases. Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe","volume":"18","author":"Cant\u00f3n","year":"2012","journal-title":"Clinical Microbiology and Infection"},{"key":"10.1016\/j.jgar.2013.01.005_bib0225","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.mib.2010.09.006","article-title":"Alarming \u03b2-lactamase-mediated resistance in multidrug-resistant Enterobacteriaceae","volume":"13","author":"Bush","year":"2010","journal-title":"Current Opinion in Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0230","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1128\/AAC.00899-09","article-title":"Detection of KPC in Acinetobacter spp. in Puerto Rico","volume":"54","author":"Robledo","year":"2010","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0235","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1007\/s10096-011-1481-x","article-title":"blaKPC and rmtB on a single plasmid in Enterobacter amnigenus and Klebsiella pneumoniae isolates from the same patient","volume":"31","author":"Sheng","year":"2012","journal-title":"European Journal of Clinical Microbiology and Infectious Diseases"},{"key":"10.1016\/j.jgar.2013.01.005_bib0240","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.diagmicrobio.2009.10.003","article-title":"Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 and ArmA 16S rRNA methylase conferring high-level aminoglycoside resistance in carbapenem-resistant Enterobacter cloacae in China","volume":"66","author":"Wu","year":"2010","journal-title":"Diagnostic Microbiology and Infectious Disease"},{"key":"10.1016\/j.jgar.2013.01.005_bib0245","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1128\/AAC.01099-09","article-title":"Phenotypic and genotypic characterization of Enterobacteriaceae with decreased susceptibility to carbapenems: results from large hospital-based surveillance studies in China","volume":"54","author":"Yang","year":"2010","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0250","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/jac\/dkn484","article-title":"Carbapenem-hydrolysing \u03b2-lactamase KPC-2 in Klebsiella pneumoniae isolated in Rio de Janeiro","volume":"63","author":"Peirano","year":"2009","journal-title":"Brazil. Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0255","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1093\/jac\/dkp207","article-title":"Clonal spread of KPC-2 carbapenemase-producing Klebsiella pneumoniae strains in Greece","volume":"64","author":"Pournaras","year":"2009","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0260","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1086\/649865","article-title":"An outbreak of infection due to \u03b2-lactamase Klebsiella pneumoniae carbapenemase 2-producing K. pneumoniae in a Greek university hospital: molecular characterization, epidemiology, and outcomes","volume":"50","author":"Souli","year":"2010","journal-title":"Clinical Infectious Diseases"},{"key":"10.1016\/j.jgar.2013.01.005_bib0265","doi-asserted-by":"crossref","first-page":"E52","DOI":"10.1111\/j.1469-0691.2011.03738.x","article-title":"Prevalence of 16S rRNA methylase genes in Enterobacteriaceae isolates from a Greek university hospital","volume":"18","author":"Galani","year":"2012","journal-title":"Clinical Microbiology and Infection"},{"key":"10.1016\/j.jgar.2013.01.005_bib0270","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.1128\/JCM.00459-12","article-title":"Imported KPC-producing Klebsiella pneumoniae clones in a Greek hospital: impact of infection control measures to restrain their dissemination","volume":"50","author":"Poulou","year":"2012","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0275","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/jac\/dkp417","article-title":"Plasmid pKpQIL encoding KPC-3 and TEM-1 confers carbapenem resistance in an extremely drug-resistant epidemic Klebsiella pneumoniae strain","volume":"65","author":"Leavitt","year":"2010","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0280","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1093\/jac\/dkp272","article-title":"Detection of aac(6\u2032)-Ib-cr in KPC-producing Klebsiella pneumoniae isolates from Tel Aviv, Israel","volume":"64","author":"Chmelnitsky","year":"2009","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0285","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1093\/jac\/dkp018","article-title":"Emergence of clonally related Klebsiella pneumoniae isolates of sequence type 258 producing plasmid-mediated KPC carbapenemase in Norway and Sweden","volume":"63","author":"Samuelsen","year":"2009","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0290","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1128\/AAC.00436-09","article-title":"Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland","volume":"53","author":"Baraniak","year":"2009","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0295","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1128\/AAC.00011-10","article-title":"KPC-producing extreme drug-resistant Klebsiella pneumoniae isolate from a patient with diabetes mellitus and chronic renal failure on hemodialysis in South Korea","volume":"54","author":"Rhee","year":"2010","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0300","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1099\/jmm.0.012575-0","article-title":"Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae","volume":"58","author":"Landman","year":"2009","journal-title":"Journal of Medical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0305","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/jac\/dkn547","article-title":"Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA","volume":"63","author":"Endimiani","year":"2009","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0310","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1128\/JB.00043-12","article-title":"Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain isolated from human sputum","volume":"194","author":"Liu","year":"2012","journal-title":"Journal of Bacteriology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0315","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1128\/AAC.05519-11","article-title":"Emergence of Proteus mirabilis harboring blaKPC-2 and qnrD in a Chinese hospital","volume":"56","author":"Hu","year":"2012","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0320","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1093\/jac\/dks046","article-title":"Carbapenem-resistant Gram-negative bacilli in Canada 2009-10: results from the Canadian Nosocomial Infection Surveillance Program (CNISP)","volume":"67","author":"Mataseje","year":"2012","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0325","doi-asserted-by":"crossref","first-page":"3793","DOI":"10.1128\/JCM.01773-09","article-title":"Emergence in Italy of Klebsiella pneumoniae sequence type 258 producing KPC-3 carbapenemase","volume":"47","author":"Giani","year":"2009","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0330","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1093\/jac\/dkq174","article-title":"Emergence of blaKPC-3-Tn4401a associated with a pKPN3\/4-like plasmid within ST384 and ST388 Klebsiella pneumoniae clones in Spain","volume":"65","author":"Curiao","year":"2010","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0335","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1128\/JCM.02397-09","article-title":"Clonal dissemination of Klebsiella pneumoniae carbapenemase KPC-3 in Long Beach, California","volume":"48","author":"Le","year":"2010","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0340","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1128\/JCM.00197-07","article-title":"Successive emergence of extended-spectrum \u03b2-lactamase-producing and carbapenemase-producing Enterobacter aerogenes isolates in a university hospital","volume":"46","author":"Biendo","year":"2008","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0345","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.diagmicrobio.2009.07.002","article-title":"Combination of IMP-4 metallo-\u03b2-lactamase production and porin deficiency causes carbapenem resistance in a Klebsiella oxytoca clinical isolate","volume":"65","author":"Chen","year":"2009","journal-title":"Diagnostic Microbiology and Infectious Disease"},{"key":"10.1016\/j.jgar.2013.01.005_bib0350","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1099\/jmm.0.043000-0","article-title":"Outbreak of pulmonary infection caused by Klebsiella pneumoniae isolates harbouring blaIMP-4 and blaDHA-1 in a neonatal intensive care unit in China","volume":"61","author":"Yu","year":"2012","journal-title":"Journal of Medical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0355","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.arcmed.2010.05.006","article-title":"In169, a new class 1 integron that encoded blaIMP-18 in a multidrug-resistant Pseudomonas aeruginosa isolate from Mexico","volume":"41","author":"S\u00e1nchez-Martinez","year":"2010","journal-title":"Archives of Medical Research"},{"key":"10.1016\/j.jgar.2013.01.005_bib0360","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1093\/jac\/dkr336","article-title":"Interspecies dissemination of a novel class 1 integron carrying blaIMP-19 among Acinetobacter species in Japan","volume":"66","author":"Yamamoto","year":"2011","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0365","doi-asserted-by":"crossref","first-page":"3036","DOI":"10.1128\/AAC.00049-11","article-title":"Emergence of NDM-1-producing Enterobacteriaceae in Belgium","volume":"55","author":"Bogaerts","year":"2011","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0370","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1128\/AAC.01497-10","article-title":"Early dissemination of NDM-1- and OXA-181-producing Enterobacteriaceae in Indian hospitals: report from the SENTRY Antimicrobial Surveillance Program (2006\u20132007)","volume":"55","author":"Castanheira","year":"2011","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0375","doi-asserted-by":"crossref","first-page":"4914","DOI":"10.1128\/AAC.00878-10","article-title":"Emergence of metallo-\u03b2-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia","volume":"54","author":"Poirel","year":"2010","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0380","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.1128\/AAC.00165-11","article-title":"Analysis of the resistome of a multidrug-resistant NDM-1-producing Escherichia coli strain by high-throughput genome sequencing","volume":"55","author":"Poirel","year":"2011","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0385","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1128\/AAC.01585-10","article-title":"NDM-1-producing Escherichia coli in Germany","volume":"55","author":"Pfeifer","year":"2011","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0390","doi-asserted-by":"crossref","first-page":"4402","DOI":"10.1128\/AAC.00642-11","article-title":"First description of an Escherichia coli strain producing NDM-1 carbapenemase in Spain","volume":"55","author":"Sole","year":"2011","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0395","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1093\/jac\/dkr174","article-title":"Molecular analysis of NDM-1-producing enterobacterial isolates from Geneva, Switzerland","volume":"66","author":"Poirel","year":"2011","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0400","doi-asserted-by":"crossref","first-page":"532","DOI":"10.3201\/eid1803.1103890","article-title":"NDM-1-producing Klebsiella pneumoniae, Croatia","volume":"18","author":"Mazzariol","year":"2012","journal-title":"Emerging Infectious Diseases"},{"key":"10.1016\/j.jgar.2013.01.005_bib0405","doi-asserted-by":"crossref","first-page":"5046","DOI":"10.1128\/AAC.00774-09","article-title":"Characterization of a new metallo-\u03b2-lactamase gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India","volume":"53","author":"Yong","year":"2009","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0410","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1128\/AAC.01247-10","article-title":"Detection of NDM-1-producing Klebsiella pneumoniae in Kenya","volume":"55","author":"Poirel","year":"2011","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0415","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1093\/jac\/dks114","article-title":"Complete sequencing of an IncH plasmid carrying the blaNDM-1, blaCTX-M-15 and qnrB1 genes","volume":"67","author":"Villa","year":"2012","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0420","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1093\/jac\/dkq428","article-title":"NDM-1-producing Klebsiella pneumoniae isolated in the Sultanate of Oman","volume":"66","author":"Poirel","year":"2011","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0425","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1128\/AAC.05604-11","article-title":"Complete sequence of a novel 178-kilobase plasmid carrying blaNDM-1 in a Providencia stuartii strain isolated in Afghanistan","volume":"56","author":"McGann","year":"2012","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0430","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1469-0691.2010.03225.x","article-title":"Metallo-\u03b2-lactamases among Enterobacteriaceae from routine samples in an Italian tertiary-care hospital and long-term care facilities during 2008","volume":"17","author":"Aschbacher","year":"2011","journal-title":"Clinical Microbiology and Infection"},{"key":"10.1016\/j.jgar.2013.01.005_bib0435","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1093\/jac\/dkp504","article-title":"Spread of plasmids containing the blaVIM-1 and blaCTX-M genes and the qnr determinant in Enterobacter cloacae Klebsiella pneumoniae and Klebsiella oxytoca isolates","volume":"65","author":"Mir\u00f3","year":"2010","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0440","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.ijantimicag.2012.01.006","article-title":"Role of IncHI2 plasmids harbouring blaVIM-1, blaCTX-M-9, aac(6\u2032)-Ib and qnrA genes in the spread of multiresistant Enterobacter cloacae and Klebsiella pneumoniae strains in different units at Hospital Vall d\u2019Hebron, Barcelona, Spain","volume":"39","author":"Coelho","year":"2012","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.jgar.2013.01.005_bib0445","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.ijantimicag.2010.05.004","article-title":"Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae and Escherichia coli isolates possessing blaVIM-1 in Greece","volume":"36","author":"Galani","year":"2010","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.jgar.2013.01.005_bib0450","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1111\/j.1469-0691.2011.03532.x","article-title":"Molecular characterization of VIM-producing Klebsiella pneumoniae from Scandinavia reveals genetic relatedness with international clonal complexes encoding transferable multidrug resistance","volume":"17","author":"Samuelsen","year":"2011","journal-title":"Clinical Microbiology and Infection"},{"key":"10.1016\/j.jgar.2013.01.005_bib0455","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1469-0691.2009.02888.x","article-title":"Detection and characterization of Enterobacteriaceae producing metallo-\u03b2-lactamases in a tertiary-care hospital in Spain","volume":"16","author":"Cendejas","year":"2010","journal-title":"Clinical Microbiology and Infection"},{"key":"10.1016\/j.jgar.2013.01.005_bib0460","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1128\/JCM.00020-12","article-title":"Fecal carriage of carbapenemase-producing Enterobacteriaceae: a hidden reservoir in hospitalized and nonhospitalized patients","volume":"50","author":"Gijon","year":"2012","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0465","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.diagmicrobio.2008.09.002","article-title":"Spread of CTX-M-type extended-spectrum \u03b2-lactamases among bloodstream isolates of Escherichia coli and Klebsiella pneumoniae from a Korean hospital","volume":"63","author":"Lee","year":"2009","journal-title":"Diagnostic Microbiology and Infectious Disease"},{"key":"10.1016\/j.jgar.2013.01.005_bib0470","doi-asserted-by":"crossref","first-page":"2889","DOI":"10.1128\/AAC.00398-06","article-title":"Class II transposon-borne structure harboring metallo-\u03b2-lactamase gene blaVIM-2 in Pseudomonas putida","volume":"50","author":"Poirel","year":"2006","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0475","doi-asserted-by":"crossref","first-page":"E214","DOI":"10.1111\/j.1469-0691.2012.03827.x","article-title":"First detection of VIM-4 metallo-\u03b2-lactamase-producing Escherichia coli in Russia","volume":"18","author":"Shevchenko","year":"2012","journal-title":"Clinical Microbiology and Infection"},{"key":"10.1016\/j.jgar.2013.01.005_bib0480","doi-asserted-by":"crossref","first-page":"4198","DOI":"10.1128\/AAC.00663-06","article-title":"Emergence of multidrug-resistant Klebsiella pneumoniae isolates producing VIM-4 metallo-\u03b2-lactamase, CTX-M-15 extended-spectrum \u03b2-lactamase, and CMY-4 AmpC \u03b2-lactamase in a Tunisian university hospital","volume":"50","author":"Ktari","year":"2006","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0485","doi-asserted-by":"crossref","first-page":"4793","DOI":"10.1128\/AAC.48.12.4793-4799.2004","article-title":"Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A \u03b2-lactamase KPC-3, in a New York Medical Center","volume":"48","author":"Woodford","year":"2004","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0490","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.7164\/antibiotics.43.1302","article-title":"R-plasmid mediated transfer of \u03b2-lactam resistance in Bacteroides fragilis","volume":"43","author":"Yamaoka","year":"1990","journal-title":"Journal of Antibiotics (Tokyo)"},{"key":"10.1016\/j.jgar.2013.01.005_bib0495","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S1473-3099(10)70143-2","article-title":"Emergence of a new antibiotic resistance mechanism in India Pakistan, and the UK: a molecular, biological, and epidemiological study","volume":"10","author":"Kumarasamy","year":"2010","journal-title":"Lancet Infectious Diseases"},{"key":"10.1016\/j.jgar.2013.01.005_bib0500","doi-asserted-by":"crossref","first-page":"4048","DOI":"10.1128\/AAC.00690-09","article-title":"Emerging Klebsiella pneumoniae isolates coproducing KPC-2 and VIM-1 carbapenemases","volume":"53","author":"Giakkoupi","year":"2009","journal-title":"Antimicrobial Agents and Chemotherapy"},{"issue":"pii","key":"10.1016\/j.jgar.2013.01.005_bib0505","first-page":"19990","article-title":"Detection of Citrobacter koseri carrying \u03b2-lactamase KPC-2 in a hospitalised patient, Greece, July 2011","volume":"16","author":"Mavroidi","year":"2011","journal-title":"Euro Surveillance"},{"key":"10.1016\/j.jgar.2013.01.005_bib0510","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1093\/jac\/dkq190","article-title":"Detection of the new metallo-\u03b2-lactamase VIM-19 along with KPC-2 CMY-2 and CTX-M-15 in Klebsiella pneumoniae","volume":"65","author":"Pournaras","year":"2010","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0515","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/jac\/dkr431","article-title":"Emergence of Klebsiella pneumoniae isolate co-producing NDM-1 with KPC-2 from India","volume":"67","author":"Kumarasamy","year":"2012","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0520","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.ijantimicag.2012.02.009","article-title":"First report of a Pseudomonas aeruginosa clinical isolate co-harbouring KPC-2 and IMP-18 carbapenemases","volume":"39","author":"Mart\u00ednez","year":"2012","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.jgar.2013.01.005_bib0525","series-title":"52nd interscience conference on antimicrobial agents and chemotherapy (ICAAC), 9\u201312 September 2012, San Francisco, CA","article-title":"Characterization of carbapenem-resistant Enterobacteriaceae (CRE) in an Indiana health care setting (2009\u20132012)","author":"Bush","year":"2012"},{"key":"10.1016\/j.jgar.2013.01.005_bib0530","doi-asserted-by":"crossref","first-page":"128","DOI":"10.3904\/kjim.2012.27.2.128","article-title":"Current epidemiology and growing resistance of Gram-negative pathogens","volume":"27","author":"Livermore","year":"2012","journal-title":"Korean Journal of Internal Medicine"},{"key":"10.1016\/j.jgar.2013.01.005_bib0535","doi-asserted-by":"crossref","first-page":"2962","DOI":"10.1128\/AAC.01341-07","article-title":"Plasmid-mediated qnrB2 and carbapenemase gene blaKPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates","volume":"52","author":"Chmelnitsky","year":"2008","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0540","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1099\/jmm.0.044115-0","article-title":"Genetic characteristics of one highly multi-drug-resistant strain of Klebsiella ozaenae","volume":"61","author":"Huang","year":"2012","journal-title":"Journal of Medical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0545","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1128\/AAC.00158-08","article-title":"Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States","volume":"52","author":"Endimiani","year":"2008","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0550","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1093\/jac\/dkr552","article-title":"A carbapenem-resistant Klebsiella pneumoniae epidemic clone in Jerusalem: sequence type 512 carrying a plasmid encoding aac(6\u2032)-Ib","volume":"67","author":"Warburg","year":"2012","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0555","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.ijantimicag.2012.01.020","article-title":"Emergence of a novel multidrug-resistant Pseudomonas aeruginosa strain producing IMP-type metallo-\u03b2-lactamases and AAC(6\u2019)-Iae in Japan","volume":"39","author":"Kitao","year":"2012","journal-title":"International Journal of Antimicrobial Agents"},{"key":"10.1016\/j.jgar.2013.01.005_bib0560","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1099\/jmm.0.010017-0","article-title":"Relevance of resistance levels to carbapenems and integron-borne blaIMP-1, blaIMP-7, blaIMP-10 and blaVIM-2 in clinical isolates of Pseudomonas aeruginosa","volume":"58","author":"Zhao","year":"2009","journal-title":"Journal of Medical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0565","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1093\/jac\/dks357","article-title":"Complete sequencing of an IncHI1 plasmid encoding the carbapenemase NDM-1, the ArmA 16S RNA methylase and a resistance\u2013nodulation\u2013cell division\/multidrug efflux pump","volume":"68","author":"Dolejska","year":"2013","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0570","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1128\/AAC.00443-07","article-title":"High prevalence of metallo-\u03b2-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil","volume":"51","author":"Doi","year":"2007","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0575","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1128\/AAC.00138-11","article-title":"Isolation of Pseudomonas aeruginosa coproducing metallo-\u03b2-lactamase SPM-1 and 16S rRNA methylase RmtD1 in an urban river","volume":"55","author":"Fontes","year":"2011","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0580","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/jac\/dkm508","article-title":"Linkage of acquired quinolone resistance (qnrS1) and metallo-\u03b2-lactamase (blaVIM-1) genes in multiple species of Enterobacteriaceae from Bolzano, Italy","volume":"61","author":"Aschbacher","year":"2008","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0585","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1093\/jac\/dkm020","article-title":"Characterization of In3Mor, a new integron carrying VIM-1 metallo-\u03b2-lactamase and sat1 gene, from Morganella morganii","volume":"59","author":"Tsakris","year":"2007","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0590","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1093\/jac\/dks367","article-title":"Complete nucleotide sequence of the large conjugative pTC2 multireplicon plasmid encoding the VIM-1 metallo-\u03b2-lactamase","volume":"68","author":"Drieux","year":"2013","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0595","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1128\/AAC.44.4.891-897.2000","article-title":"Characterization of VIM-2, a carbapenem-hydrolyzing metallo-\u03b2-lactamase and its plasmid- and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France","volume":"44","author":"Poirel","year":"2000","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0600","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1093\/jac\/dkg299","article-title":"Evolution of an integron carrying blaVIM-2 in Eastern Europe: report from the SENTRY Antimicrobial Surveillance Program","volume":"52","author":"Walsh","year":"2003","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0605","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1128\/AAC.47.5.1746-1748.2003","article-title":"Novel 3-N-aminoglycoside acetyltransferase gene, aac(3)-Ic, from a Pseudomonas aeruginosa integron","volume":"47","author":"Riccio","year":"2003","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0610","doi-asserted-by":"crossref","first-page":"4242","DOI":"10.1128\/JCM.01558-06","article-title":"Integrons containing the VIM-2 metallo-\u03b2-lactamase gene among imipenem-resistant Pseudomonas aeruginosa strains from different Chinese hospitals","volume":"44","author":"Yu","year":"2006","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0615","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s12275-008-0272-2","article-title":"Analysis of a novel class 1 integron containing metallo-\u03b2-lactamase gene VIM-2 in Pseudomonas aeruginosa","volume":"47","author":"Jeong","year":"2009","journal-title":"Journal of Microbiology"},{"key":"10.1016\/j.jgar.2013.01.005_bib0620","doi-asserted-by":"crossref","first-page":"3589","DOI":"10.1128\/AAC.00465-08","article-title":"Characterization of the new metallo-\u03b2-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain","volume":"52","author":"Juan","year":"2008","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0625","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1093\/jac\/dkq408","article-title":"Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates","volume":"66","author":"Livermore","year":"2011","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.jgar.2013.01.005_bib0630","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.coph.2012.06.003","article-title":"Improving known classes of antibiotics: an optimistic approach for the future","volume":"12","author":"Bush","year":"2012","journal-title":"Current Opinion in Pharmacology"}],"container-title":["Journal of Global Antimicrobial Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716513000064?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716513000064?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T02:16:31Z","timestamp":1562811391000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213716513000064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":126,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S2213716513000064"],"URL":"https:\/\/doi.org\/10.1016\/j.jgar.2013.01.005","relation":{},"ISSN":["2213-7165"],"issn-type":[{"value":"2213-7165","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}