{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:08:11Z","timestamp":1787317691495,"version":"build-2736575974"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T00:00:00Z","timestamp":1583452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007637","name":"Administrative Department of Science, Technology and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007637","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Global Antimicrobial Resistance"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.jgar.2020.02.033","type":"journal-article","created":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T17:19:35Z","timestamp":1584638375000},"page":"358-366","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Multidrug resistance and diversity of resistance profiles in carbapenem-resistant Gram-negative bacilli throughout a wastewater treatment plant in Colombia"],"prefix":"10.1016","volume":"22","author":[{"given":"E.A.","family":"Rodr\u00edguez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.M.","family":"Garz\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.D.","family":"G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Natalia","family":"Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgar.2020.02.033_bib0005","first-page":"671","article-title":"Antibiotic resistance in the aquatic environment","volume":"62","author":"Marti","year":"2013","journal-title":"Compr Anal Chem"},{"key":"10.1016\/j.jgar.2020.02.033_bib0010","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.jmii.2014.04.009","article-title":"Antimicrobial consumption and resistance in five Gram-negative bacterial species in a hospital from 2003 to 2011","volume":"48","author":"Lee","year":"2015","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.jgar.2020.02.033_bib0015","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1186\/s12879-016-1805-7","article-title":"Molecular epidemiology of carbapenem resistant gram-negative bacilli from infected pediatric population in tertiary-care hospitals in Medell\u00edn, Colombia: an increasing problem","volume":"16","author":"Vanegas","year":"2016","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jgar.2020.02.033_bib0020","series-title":"Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics","author":"WHO","year":"2017"},{"key":"10.1016\/j.jgar.2020.02.033_bib0025","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1097\/PAT.0000000000000302","article-title":"Active surveillance for multidrug-resistant Gram-negative bacteria in the intensive care unit","volume":"47","author":"Abbott","year":"2015","journal-title":"Pathology"},{"key":"10.1016\/j.jgar.2020.02.033_bib0030","doi-asserted-by":"crossref","first-page":"E143","DOI":"10.1016\/j.ajic.2017.06.002","article-title":"Antimicrobial resistance of 3 types of Gram-negative bacteria isolated from hospital surfaces and the hands of health care workers","volume":"45","author":"Wang","year":"2017","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jgar.2020.02.033_bib0035","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.watres.2014.05.006","article-title":"Characterization of ciprofloxacin-resistant isolates from a wastewater treatment plant and its receiving river","volume":"61","author":"Marti","year":"2014","journal-title":"Water Res"},{"key":"10.1016\/j.jgar.2020.02.033_bib0040","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1016\/j.chemosphere.2011.04.076","article-title":"Antibiotics pollution in Jiulong River estuary: source, distribution and bacterial resistance","volume":"84","author":"Zheng","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.jgar.2020.02.033_bib0045","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1016\/j.watres.2013.01.010","article-title":"Antibiotic resistance, antimicrobial residues and bacterial community composition in urban wastewater","volume":"47","author":"Novo","year":"2013","journal-title":"Water Res"},{"key":"10.1016\/j.jgar.2020.02.033_bib0050","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1016\/j.watres.2013.04.047","article-title":"Persistence and prevalence of pathogenic and extended-spectrum beta-lactamase-producing Escherichia coli in municipal wastewater treatment plant receiving slaughterhouse wastewater","volume":"47","author":"Diallo","year":"2013","journal-title":"Water Res"},{"key":"10.1016\/j.jgar.2020.02.033_bib0055","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.watres.2017.09.007","article-title":"The fate of carbapenem-resistant bacteria in a wastewater treatment plant","volume":"126","author":"Hrenovic","year":"2017","journal-title":"Water Res"},{"key":"10.1016\/j.jgar.2020.02.033_bib0060","doi-asserted-by":"crossref","first-page":"24","DOI":"10.7705\/biomedica.v35i4.2610","volume":"35","author":"Ocampo","year":"2015","journal-title":"Biom\u00e9dica"},{"key":"10.1016\/j.jgar.2020.02.033_bib0065","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1093\/jac\/dkv181","article-title":"Rossolini GM. OXA-372, a novel carbapenem-hydrolysing class D \u03b2-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant","volume":"70","author":"Antonelli","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2020.02.033_bib0070","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.watres.2014.02.041","article-title":"High dissemination of extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae in effluents from wastewater treatment plants","volume":"56","author":"Ojer-Usoz","year":"2014","journal-title":"Water Res"},{"key":"10.1016\/j.jgar.2020.02.033_bib0075","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.scitotenv.2016.12.063","article-title":"Discharge of KPC-2 genes from the WWTPs contributed to their enriched abundance in the receiving river","volume":"581\u2013582","author":"Yang","year":"2017","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jgar.2020.02.033_bib0080","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1128\/AEM.67.1.190-197.2001","article-title":"Phylogenetic specificity and reproducibility and new method for analysis of terminal restriction fragment profiles of 16S rRNA genes from bacterial communities","volume":"67","author":"Dunbar","year":"2001","journal-title":"Appl Env Microbiol"},{"key":"10.1016\/j.jgar.2020.02.033_bib0085","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1093\/bioinformatics\/bts199","article-title":"Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data","volume":"28","author":"Kearse","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jgar.2020.02.033_bib0090","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.diagmicrobio.2010.12.002","article-title":"Multiplex PCR for detection of acquired carbapenemase genes","volume":"70","author":"Poirel","year":"2011","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.jgar.2020.02.033_bib0095","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/jac\/dkl481","article-title":"Multiplex PCR for rapid detection of genes encoding acquired metallo-\u03b2-lactamases","volume":"59","author":"Ellington","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2020.02.033_bib0100","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8042603","article-title":"Isolation, identification, and antimicrobial susceptibility of bacteria associated with waterpipe contaminants in selected area of Saudi Arabia","volume":"2017","author":"Alaidarous","year":"2017","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.jgar.2020.02.033_bib0105","first-page":"132","article-title":"Susceptibilidad antimicrobiana de aislamientos de Escherichia coli procedentes de ecosistemas dulceacu\u00edcolas. (Spanish) [Antimicrobial susceptibility of Escherichia coli isolated from river water ecosystems]","volume":"64","author":"Romeu \u00c1lvarez","year":"2012","journal-title":"Rev Cubana Med Trop"},{"key":"10.1016\/j.jgar.2020.02.033_bib0110","series-title":"M100 performance standards for antimicrobial susceptibility testing","author":"Clinical and Laboratory Standards Institute","year":"2017"},{"key":"10.1016\/j.jgar.2020.02.033_bib0115","volume":"Vol. 30","author":"Clinical and Laboratory Standards Institute","year":"2010"},{"key":"10.1016\/j.jgar.2020.02.033_bib0120","series-title":"Breakpoint tables for interpretation of MICs and zone diameters, version 80","first-page":"0","author":"The European Committee on Antimicrobial Susceptibility Testing (EUCAST)","year":"2018"},{"key":"10.1016\/j.jgar.2020.02.033_bib0125","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jgar.2020.02.033_bib0130","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.diagmicrobio.2013.02.001","article-title":"The route of antimicrobial resistance from the hospital effluent to the environment: focus on the occurrence of KPC-producing Aeromonas spp. and Enterobacteriaceae in sewage","volume":"76","author":"Pic\u00e3o","year":"2013","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.jgar.2020.02.033_bib0135","first-page":"1","article-title":"Prevalence and fate of carbapenemase genes in a wastewater treatment plant in northern China","volume":"11","author":"Yang","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.jgar.2020.02.033_bib0140","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.ijantimicag.2014.10.016","article-title":"Occurrence of carbapenemase-producing bacteria in coastal recreational waters","volume":"45","author":"Montezzi","year":"2015","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jgar.2020.02.033_bib0145","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1111\/jam.12936","article-title":"Diversity and antibiotic resistance profiles of Pseudomonads from a hospital wastewater treatment plant","volume":"119","author":"Santoro","year":"2015","journal-title":"J Appl Microbiol"},{"key":"10.1016\/j.jgar.2020.02.033_bib0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.jece.2018.02.004","article-title":"Elimination of carbapenem resistant Klebsiella pneumoniae in water by UV-C, UV-C\/persulfate and UV-C\/H2O2. Evaluation of response to antibiotic, residual effect of the processes and removal of resistance gene","volume":"8","author":"Serna-Galvis","year":"2020","journal-title":"J Environ Chem Eng"},{"key":"10.1016\/j.jgar.2020.02.033_bib0155","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.ecoenv.2017.10.071","article-title":"Spread of multidrug-resistant Escherichia coli harboring integron via swine farm waste water treatment plant","volume":"149","author":"Park","year":"2018","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.1016\/j.jgar.2020.02.033_bib0160","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.jmii.2012.08.008","article-title":"Complexity of \u03b2-lactamases among clinical Aeromonas isolates and its clinical implications","volume":"45","author":"Chen","year":"2012","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.jgar.2020.02.033_bib0165","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1099\/jmm.0.038323-0","article-title":"Distribution and phenotypic and genotypic detection of a metallo-\u03b2-lactamase, CphA, among bacteraemic Aeromonas isolates","volume":"61","author":"Wu","year":"2012","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.jgar.2020.02.033_bib0170","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1128\/JCM.38.5.1791-1796.2000","article-title":"Occurrence and detection of AmpC beta-lactamases among Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates at a veterans medical center","volume":"38","author":"Coudron","year":"2000","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jgar.2020.02.033_bib0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.ppat.1004949","article-title":"Natural variants of the KPC-2 carbapenemase have evolved increased catalytic efficiency for ceftazidime hydrolysis at the cost of enzyme stability","volume":"11","author":"Mehta","year":"2015","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.jgar.2020.02.033_bib0180","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S1473-3099(09)70054-4","article-title":"The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria","volume":"9","author":"Nordmann","year":"2009","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jgar.2020.02.033_bib0185","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.ajic.2006.05.238","article-title":"Resistance in gram-negative bacteria: Enterobacteriaceae","volume":"34","author":"Paterson","year":"2006","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.jgar.2020.02.033_bib0190","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.watres.2016.11.056","article-title":"Identification of new bacteria harboring qnrS and aac(6\u2032)-Ib\/cr and mutations possibly involved in fluoroquinolone resistance in raw sewage and activated sludge samples from a full-scale WWTP","volume":"110","author":"Paiva","year":"2017","journal-title":"Water Res"},{"key":"10.1016\/j.jgar.2020.02.033_bib0195","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.scitotenv.2015.10.124","article-title":"Quinolone resistant Aeromonas spp. as carriers and potential tracers of acquired antibiotic resistance in hospital and municipal wastewater","volume":"542","author":"Varela","year":"2016","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jgar.2020.02.033_bib0200","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1574-6941.2006.00268.x","article-title":"Antimicrobial resistance patterns in Enterobacteriaceae isolated from an urban wastewater treatment plant","volume":"60","author":"Ferreira Da Silva","year":"2007","journal-title":"FEMS Microbiol Ecol"},{"key":"10.1016\/j.jgar.2020.02.033_bib0205","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ecoenv.2016.10.031","article-title":"Characterization of CTX-M enzymes, quinolone resistance determinants, and antimicrobial residues from hospital sewage, wastewater treatment plant, and river water","volume":"136","author":"Conte","year":"2017","journal-title":"Ecotoxicol Environ Saf"}],"container-title":["Journal of Global Antimicrobial Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716520300643?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716520300643?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T10:01:00Z","timestamp":1761991260000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213716520300643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":41,"alternative-id":["S2213716520300643"],"URL":"https:\/\/doi.org\/10.1016\/j.jgar.2020.02.033","relation":{},"ISSN":["2213-7165"],"issn-type":[{"value":"2213-7165","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multidrug resistance and diversity of resistance profiles in carbapenem-resistant Gram-negative bacilli throughout a wastewater treatment plant in Colombia","name":"articletitle","label":"Article Title"},{"value":"Journal of Global Antimicrobial Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgar.2020.02.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.","name":"copyright","label":"Copyright"}]}}