{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T23:56:55Z","timestamp":1787702215484,"version":"build-2784847793"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,12]],"date-time":"2020-05-12T00:00:00Z","timestamp":1589241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Global Antimicrobial Resistance"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.jgar.2020.05.003","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T12:28:19Z","timestamp":1589804899000},"page":"646-650","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Low prevalence of combined linezolid- and vancomycin-resistant Enterococcus faecium from hospital admission screening in an endemic region in Germany"],"prefix":"10.1016","volume":"22","author":[{"given":"Alexandra","family":"Heininger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin","family":"Bootsveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0499-2460","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Boutin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Nurjadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgar.2020.05.003_bib0005","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S1473-3099(17)30753-3","article-title":"Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis","volume":"18","author":"Tacconelli","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.jgar.2020.05.003_bib0010","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1093\/jac\/dku035","article-title":"Dramatic increase in vancomycin-resistant enterococci in Germany","volume":"69","author":"Gastmeier","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2020.05.003_bib0015","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s13756-018-0353-x","article-title":"Continuous increase of vancomycin resistance in enterococci causing nosocomial infections in Germany \u2013 10 years of surveillance","volume":"7","author":"Remschmidt","year":"2018","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.jgar.2020.05.003_bib0020","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.drup.2018.10.002","article-title":"Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: towards a common nomenclature","volume":"40","author":"Bender","year":"2018","journal-title":"Drug Resist Updat"},{"key":"10.1016\/j.jgar.2020.05.003_bib0025","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13756-016-0131-6","article-title":"Emergence of linezolid- and vancomycin-resistant Enterococcus faecium in a department for hematologic stem cell transplantation","volume":"5","author":"Krull","year":"2016","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.jgar.2020.05.003_bib0030","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1093\/jac\/dkz367","article-title":"Phenotypic and genotypic characterization of linezolid-resistant Enterococcus faecium from the USA and Pakistan","volume":"74","author":"Wardenburg","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2020.05.003_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2019.10.014","article-title":"Comparative genomic analysis revealed high prevalence of inter-species in vivo transfer of carbapenem resistance plasmids in patients with hematological malignancies","volume":"26","author":"Kocer","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jgar.2020.05.003_bib0040","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00483-19","article-title":"Validating the AMRFinder tool and resistance gene database by using antimicrobial resistance genotype-phenotype correlations in a collection of isolates","volume":"63","author":"Feldgarden","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2020.05.003_bib0045","doi-asserted-by":"crossref","first-page":"D566","DOI":"10.1093\/nar\/gkw1004","article-title":"CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database","volume":"45","author":"Jia","year":"2017","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgar.2020.05.003_bib0050","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1093\/jac\/dks261","article-title":"Identification of acquired antimicrobial resistance genes","volume":"67","author":"Zankari","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2020.05.003_bib0055","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1128\/AAC.01310-13","article-title":"ARG-ANNOT, a new bioinformatic tool to discover antibiotic resistance genes in bacterial genomes","volume":"58","author":"Gupta","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2020.05.003_bib0060","doi-asserted-by":"crossref","first-page":"D694","DOI":"10.1093\/nar\/gkv1239","article-title":"VFDB 2016: hierarchical and refined dataset for big data analysis \u2013 10 years on","volume":"44","author":"Chen","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgar.2020.05.003_bib0065","series-title":"Snippy: fast bacterial variant calling from NGS reads version 4.5","author":"Seemann","year":"2015"},{"key":"10.1016\/j.jgar.2020.05.003_bib0070","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1093\/jac\/dkz092","article-title":"LRE-Finder, a Web tool for detection of the 23S rRNA mutations and the optrA, cfr, cfr(B) and poxtA genes encoding linezolid resistance in enterococci from whole-genome sequences","volume":"74","author":"Hasman","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2020.05.003_bib0075","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jgar.2015.02.007","article-title":"Increased frequency of linezolid resistance among clinical Enterococcus faecium isolates from German hospital patients","volume":"3","author":"Klare","year":"2015","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.jgar.2020.05.003_bib0080","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13756-019-0573-8","article-title":"Near-ubiquitous presence of a vancomycin-resistant Enterococcus faecium ST117\/CT71\/vanB-clone in the Rhine-Main metropolitan area of Germany","volume":"8","author":"Falgenhauer","year":"2019","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.jgar.2020.05.003_bib0085","doi-asserted-by":"crossref","first-page":"9368","DOI":"10.1093\/nar\/gkr626","article-title":"A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA","volume":"39","author":"Desmolaize","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgar.2020.05.003_bib0090","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1128\/AAC.00183-11","article-title":"Inactivation of the indigenous methyltransferase RlmN in Staphylococcus aureus increases linezolid resistance","volume":"55","author":"LaMarre","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2020.05.003_bib0095","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.ijantimicag.2018.09.009","article-title":"Rapid emergence of highly variable and transferable oxazolidinone and phenicol resistance gene optrA in German Enterococcus spp. clinical isolates","volume":"52","author":"Bender","year":"2018","journal-title":"Int J Antimicrob Agents"},{"issue":"7","key":"10.1016\/j.jgar.2020.05.003_bib0100","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1093\/jac\/dkaa122","article-title":"Challenges in interpretation of WGS and epidemiological data to investigate nosocomial transmission of vancomycin-resistant Enterococcus faecium in an endemic region: incorporation of patient movement network and admission screening","volume":"75","author":"Eichel","year":"2020","journal-title":"J Antimicrob Chemother"}],"container-title":["Journal of Global Antimicrobial Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716520301296?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716520301296?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T10:01:12Z","timestamp":1761991272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213716520301296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":20,"alternative-id":["S2213716520301296"],"URL":"https:\/\/doi.org\/10.1016\/j.jgar.2020.05.003","relation":{},"ISSN":["2213-7165"],"issn-type":[{"value":"2213-7165","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low prevalence of combined linezolid- and vancomycin-resistant Enterococcus faecium from hospital admission screening in an endemic region in Germany","name":"articletitle","label":"Article Title"},{"value":"Journal of Global Antimicrobial Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgar.2020.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.","name":"copyright","label":"Copyright"}]}}