{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T06:35:52Z","timestamp":1778394952927,"version":"3.51.4"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:00:00Z","timestamp":1616544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003032","name":"ANRT","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003032","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004562","name":"Minist\u00e8re de l'Education Nationale, de l'Enseignement Superieur et de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004562","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008990","name":"Universit\u00e9 de Lorraine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008990","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Global Antimicrobial Resistance"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.jgar.2021.03.017","type":"journal-article","created":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T14:17:11Z","timestamp":1617200231000},"page":"171-180","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Characterisation of the antifungal effects of a plant-based compound, CIN-102, on the main septal filamentous fungi involved in human pathology"],"prefix":"10.1016","volume":"25","author":[{"given":"Maurine","family":"D'Agostino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Tesse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rose Anne","family":"Lavergne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrice Le","family":"Pape","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Philippe","family":"Bouchara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Pol","family":"Frippiat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Machouart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Debourgogne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgar.2021.03.017_bib0001","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.3201\/eid2007.140087","article-title":"Population-based analysis of invasive fungal infections, France, 2001\u20132010","volume":"20","author":"Bitar","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jgar.2021.03.017_bib0002","first-page":"1318","article-title":"Epidemiology of visceral fungal infection in France and in the world [in French]","volume":"65","author":"Blot","year":"2015","journal-title":"Rev Prat"},{"key":"10.1016\/j.jgar.2021.03.017_bib0003","doi-asserted-by":"crossref","DOI":"10.1592\/phco.24.3.4S.33151","article-title":"Changing strategies for the management of invasive fungal infections","volume":"24","author":"Rapp","year":"2004","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.jgar.2021.03.017_bib0004","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1146\/annurev-micro-030117-020345","article-title":"Molecular evolution of antifungal drug resistance","volume":"71","author":"Robbins","year":"2017","journal-title":"Ann Rev Microbiol"},{"key":"10.1016\/j.jgar.2021.03.017_bib0005","doi-asserted-by":"crossref","first-page":"3713","DOI":"10.3390\/molecules24203713","article-title":"Essential oils and their natural active compounds presenting antifungal properties","volume":"24","author":"D'Agostino","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.jgar.2021.03.017_bib0006","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.fitote.2016.05.016","article-title":"Cinnamaldehyde and its derivatives, a novel class of antifungal agents","volume":"112","author":"Shreaz","year":"2016","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jgar.2021.03.017_bib0007","doi-asserted-by":"crossref","first-page":"M2917","DOI":"10.1111\/1750-3841.13144","article-title":"Inhibitory effect of cinnamaldehyde, citral, and eugenol on aflatoxin biosynthetic gene expression and aflatoxin B1 biosynthesis in Aspergillus flavus","volume":"80","author":"Liang","year":"2015","journal-title":"J Food Sci"},{"key":"10.1016\/j.jgar.2021.03.017_bib0008","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.3390\/molecules22081271","article-title":"In vitro evaluation of sub-lethal concentrations of plant-derived antifungal compounds on Fusaria growth and mycotoxin production","volume":"22","author":"Morcia","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.jgar.2021.03.017_bib0009","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1007\/s00253-011-3152-3","article-title":"Antifungal activity of essential oils and their synergy with fluconazole against drug-resistant strains of Aspergillus fumigatus and Trichophyton rubrum","volume":"90","author":"Khan","year":"2011","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.jgar.2021.03.017_bib0010","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1093\/mmy\/myx115","article-title":"Identification of clinical isolates of Aspergillus, including cryptic species, by matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS)","volume":"56","author":"Vidal-Acu\u00f1a","year":"2018","journal-title":"Med Mycol"},{"key":"10.1016\/j.jgar.2021.03.017_bib0011","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1080\/00275514.2017.1416260","article-title":"Molecular identification and in vitro antifungal susceptibility of Scedosporium complex isolates from high-human-activity sites in Mexico","volume":"109","author":"Elizondo-Zertuche","year":"2017","journal-title":"Mycologia"},{"key":"10.1016\/j.jgar.2021.03.017_bib0012","doi-asserted-by":"crossref","first-page":"4859","DOI":"10.1038\/s41598-018-23255-z","article-title":"Identification and characterization of Fusarium proliferatum, a new species of fungi that cause fungal keratitis","volume":"8","author":"Sun","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.jgar.2021.03.017_bib0013","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1093\/bib\/5.1.82","article-title":"Analysis for free: comparing programs for sequence analysis","volume":"5","author":"Tippmann","year":"2004","journal-title":"Brief Bioinform"},{"key":"10.1016\/j.jgar.2021.03.017_bib0014","series-title":"Reference method for broth dilution antifungal susceptibility testing of filamentous fungi; approved standard\u2014second edition. CLSI document M38-A2","year":"2008"},{"issue":"Suppl 1","key":"10.1016\/j.jgar.2021.03.017_bib0015","doi-asserted-by":"crossref","first-page":"S373","DOI":"10.12980\/APJTB.4.2014C857","article-title":"Effect of essential oils on Aspergillus spore germination, growth and mycotoxin production: a potential source of botanical food preservative","volume":"4","author":"Gemeda","year":"2014","journal-title":"Asian Pac J Trop Biomed"},{"key":"10.1016\/j.jgar.2021.03.017_bib0016","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/5647182","article-title":"Synergism effect of the essential oil from Ocimum basilicum var. Maria Bonita and its major components with fluconazole and its influence on ergosterol biosynthesis","volume":"2016","author":"Cardoso","year":"2016","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.jgar.2021.03.017_bib0017","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2217\/fmb-2019-0186","article-title":"Efflux pump inhibition controls growth and enhances antifungal susceptibility of Fusarium solani species complex","volume":"15","author":"de A Cordeiro","year":"2020","journal-title":"Future Microbiol"},{"key":"10.1016\/j.jgar.2021.03.017_bib0018","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1128\/AAC.46.6.1960-1965.2002","article-title":"Method for measuring postantifungal effect in Aspergillus species","volume":"46","author":"Vitale","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2021.03.017_bib0019","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3390\/jof3020027","article-title":"MIC distributions and evaluation of fungicidal activity for amphotericin B, itraconazole, voriconazole, posaconazole and caspofungin and 20 species of pathogenic filamentous fungi determined using the CLSI broth microdilution method","volume":"3","author":"Borman","year":"2017","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.jgar.2021.03.017_bib0020","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1055\/s-0035-1546272","article-title":"Antifungal effect of essential oils against Fusarium keratitis isolates","volume":"81","author":"Homa","year":"2015","journal-title":"Planta Med"},{"key":"10.1016\/j.jgar.2021.03.017_bib0021","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3390\/jof3020018","article-title":"Reduced multidrug susceptibility profile is a common feature of opportunistic Fusarium species: Fusarium multi-drug resistant pattern","volume":"3","author":"Taj-Aldeen","year":"2017","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.jgar.2021.03.017_bib0022","doi-asserted-by":"crossref","first-page":"7148","DOI":"10.1128\/AAC.00887-15","article-title":"Emergence of TR46\/Y121F\/T289A in an Aspergillus fumigatus isolate from a Chinese patient","volume":"59","author":"Chen","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2021.03.017_bib0023","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.riam.2016.05.005","article-title":"First itraconazole resistant Aspergillus fumigatus clinical isolate harbouring a G54E substitution in Cyp51Ap in South America","volume":"34","author":"Leonardelli","year":"2017","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.jgar.2021.03.017_bib0024","doi-asserted-by":"crossref","first-page":"e52871","DOI":"10.1371\/journal.pone.0052871","article-title":"Clonal expansion and emergence of environmental multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR34\/L98H mutations in the cyp51A gene in India","volume":"7","author":"Chowdhary","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jgar.2021.03.017_bib0025","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.fct.2007.09.106","article-title":"Biological effects of essential oils\u2014a review","volume":"46","author":"Bakkali","year":"2008","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.jgar.2021.03.017_bib0026","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.mrgentox.2011.09.014","article-title":"Safrole-2\u2032,3\u2032-oxide induces cytotoxic and genotoxic effects in HepG2 cells and in mice","volume":"726","author":"Chiang","year":"2011","journal-title":"Mutat Res"},{"key":"10.1016\/j.jgar.2021.03.017_bib0027","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/15287394.2014.943865","article-title":"In vitro assessment of mutagenic and genotoxic effects of coumarin derivatives 6,7-dihydroxycoumarin and 4-methylesculetin","volume":"78","author":"Maistro","year":"2015","journal-title":"J Toxicol Environ Health A"},{"key":"10.1016\/j.jgar.2021.03.017_bib0028","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1093\/mutage\/gel017","article-title":"Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol","volume":"21","author":"Maralhas","year":"2006","journal-title":"Mutagenesis"},{"key":"10.1016\/j.jgar.2021.03.017_bib0029","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s13568-019-0769-6","article-title":"Effect of amphotericin B and voriconazole on the outgrowth of conidia of Aspergillus fumigatus followed by time-lapse microscopy","volume":"9","author":"Talas","year":"2019","journal-title":"AMB Express"},{"key":"10.1016\/j.jgar.2021.03.017_bib0030","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3390\/pharmacy3040210","article-title":"Posaconazole: an update of its clinical use","volume":"3","author":"Leung","year":"2015","journal-title":"Pharmacy (Basel)"},{"key":"10.1016\/j.jgar.2021.03.017_bib0031","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1093\/jac\/dkh066","article-title":"A comparative study of the post-antifungal effect (PAFE) of amphotericin B, triazoles and echinocandins on Aspergillus fumigatus and Candida albicans","volume":"53","author":"Manavathu","year":"2004","journal-title":"J Antimicrob Chemother"}],"container-title":["Journal of Global Antimicrobial Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716521000837?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716521000837?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T09:58:09Z","timestamp":1761991089000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213716521000837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":31,"alternative-id":["S2213716521000837"],"URL":"https:\/\/doi.org\/10.1016\/j.jgar.2021.03.017","relation":{},"ISSN":["2213-7165"],"issn-type":[{"value":"2213-7165","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterisation of the antifungal effects of a plant-based compound, CIN-102, on the main septal filamentous fungi involved in human pathology","name":"articletitle","label":"Article Title"},{"value":"Journal of Global Antimicrobial Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgar.2021.03.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.","name":"copyright","label":"Copyright"}]}}