{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T05:46:01Z","timestamp":1773812761426,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,4]],"date-time":"2023-02-04T00:00:00Z","timestamp":1675468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LY18H190004"],"award-info":[{"award-number":["LY18H190004"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Global Antimicrobial Resistance"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.jgar.2023.01.011","type":"journal-article","created":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T20:38:36Z","timestamp":1676493516000},"page":"122-130","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Characteristics of rare ST463 carbapenem-resistant Pseudomonas aeruginosa clinical isolates from blood"],"prefix":"10.1016","volume":"32","author":[{"given":"Xiaodong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0260-5738","authenticated-orcid":false,"given":"Miran","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengxin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changrui","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangkuo","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tieli","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgar.2023.01.011_bib0001","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1469-0691.2005.01161.x","article-title":"Treatment and control of severe infections caused by multiresistant Pseudomonas aeruginosa","volume":"11","author":"Rossolini","year":"2005","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jgar.2023.01.011_bib0002","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ijmm.2011.10.001","article-title":"Structure and function of OprD protein in Pseudomonas aeruginosa: from antibiotic resistance to novel therapies","volume":"302","author":"Li","year":"2012","journal-title":"Int J Med Microbiol"},{"key":"10.1016\/j.jgar.2023.01.011_bib0003","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aax1946","article-title":"\u03a976: a designed antimicrobial peptide to combat carbapenem- and tigecycline-resistant Acinetobacter baumannii","volume":"5","author":"Nagarajan","year":"2019","journal-title":"Sci Adv"},{"key":"10.1016\/j.jgar.2023.01.011_bib0004","article-title":"Carbapenem-resistant Pseudomonas aeruginosa bacteremia: risk factors for mortality and microbiologic treatment failure","volume":"61","author":"Buehrle","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2023.01.011_bib0005","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.3390\/microorganisms10091863","article-title":"A plasmid carrying blaIMP-56 in Pseudomonas aeruginosa belonging to a novel resistance plasmid family","volume":"10","author":"G\u00f3mez-Mart\u00ednez","year":"2022","journal-title":"Microorganisms"},{"key":"10.1016\/j.jgar.2023.01.011_bib0006","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01869-21","article-title":"Emergence of a KPC-90 variant that confers resistance to ceftazidime-avibactam in an ST463 carbapenem-resistant Pseudomonas aeruginosa strain","volume":"10","author":"Tu","year":"2022","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.jgar.2023.01.011_bib0007","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.981792","article-title":"Acquisition of resistance to ceftazidime-avibactam during infection treatment in Pseudomonas aeruginosa through D179Y mutation in one of two blaKPC-2 gene copies without losing carbapenem resistance","volume":"12","author":"Garc\u00eda","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jgar.2023.01.011_bib0008","doi-asserted-by":"crossref","first-page":"3128","DOI":"10.3390\/ijms22063128","article-title":"Pseudomonas aeruginosa: an audacious pathogen with an adaptable arsenal of virulence factors","volume":"22","author":"Jurado-Martin","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jgar.2023.01.011_bib0009","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1165\/rcmb.2017-0321TR","article-title":"Pseudomonas aeruginosa biofilms: host response and clinical implications in lung infections","volume":"58","author":"Maurice","year":"2018","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1016\/j.jgar.2023.01.011_bib0010","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1128\/AAC.04903-14","article-title":"Emergence of KPC-2-producing Pseudomonas aeruginosa sequence type 463 isolates in Hangzhou, China","volume":"59","author":"Hu","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2023.01.011_bib0011","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.756782","article-title":"Bloodstream infections caused by Klebsiella pneumoniae carbapenemase-producing P. aeruginosa sequence type 463, associated with high mortality rates in China: a retrospective cohort study","volume":"11","author":"Hu","year":"2021","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jgar.2023.01.011_bib0012","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/jac\/48.suppl_1.5","article-title":"Determination of minimum inhibitory concentrations","volume":"48","author":"Andrews","year":"2001","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2023.01.011_bib0013","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1002\/cpbi.102","article-title":"Using SPAdes de novo assembler","volume":"70","author":"Prjibelski","year":"2020","journal-title":"Curr Protoc Bioinformatics"},{"key":"10.1016\/j.jgar.2023.01.011_bib0014","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.3390\/nu11112794","article-title":"Punicalagin prevents inflammation in LPS-induced RAW264.7 macrophages by inhibiting FoxO3a\/autophagy signaling pathway","volume":"11","author":"Cao","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.jgar.2023.01.011_bib0015","doi-asserted-by":"crossref","first-page":"2950","DOI":"10.1128\/AEM.68.6.2950-2958.2002","article-title":"Microtiter plate assay for assessment of Listeria monocytogenes biofilm formation","volume":"68","author":"Djordjevic","year":"2002","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.jgar.2023.01.011_bib0016","doi-asserted-by":"crossref","first-page":"23347","DOI":"10.1038\/srep23347","article-title":"Attenuation of Pseudomonas aeruginosa biofilm formation by vitexin: a combinatorial study with azithromycin and gentamicin","volume":"6","author":"Das","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.jgar.2023.01.011_bib0017","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.3389\/fmicb.2017.02640","article-title":"Phytochemicals from Camellia nitidissima chi flowers reduce the pyocyanin production and motility of Pseudomonas aeruginosa PAO1","volume":"8","author":"Yang","year":"2018","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jgar.2023.01.011_bib0018","doi-asserted-by":"crossref","first-page":"4885","DOI":"10.1073\/pnas.060030097","article-title":"Inorganic polyphosphate is needed for swimming, swarming, and twitching motilities of Pseudomonas aeruginosa","volume":"97","author":"Rashid","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jgar.2023.01.011_bib0019","doi-asserted-by":"crossref","first-page":"5967","DOI":"10.1093\/nar\/gkaa377","article-title":"PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids","volume":"48","author":"Pan","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgar.2023.01.011_bib0020","first-page":"345","article-title":"Treatment options for carbapenem- resistant Gram-negative infections","volume":"115","author":"Fritzenwanker","year":"2018","journal-title":"Dtsch Arztebl Int"},{"key":"10.1016\/j.jgar.2023.01.011_bib0021","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1093\/cid\/ciy752","article-title":"Control of carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa in healthcare facilities: a systematic review and reanalysis of quasi-experimental studies","volume":"68","author":"Tomczyk","year":"2019","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jgar.2023.01.011_bib0022","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01854-22","article-title":"In vitro activity of new \u03b2-lactam-\u03b2-lactamase inhibitor combinations and comparators against clinical isolates of Gram-negative bacilli: results from the China Antimicrobial Surveillance Network (CHINET) in 2019","volume":"10","author":"Guo","year":"2022","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.jgar.2023.01.011_bib0023","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00773-21","article-title":"CrpP is not a fluoroquinolone-inactivating enzyme","volume":"65","author":"Zubyk","year":"2021","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2023.01.011_bib0024","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.ijantimicag.2004.11.012","article-title":"Alterations in the GyrA and GyrB subunits of topoisomerase II and the ParC and ParE subunits of topoisomerase IV in ciprofloxacin-resistant clinical isolates of Pseudomonas aeruginosa","volume":"25","author":"Lee","year":"2005","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.jgar.2023.01.011_bib0025","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00032-13","article-title":"Type III secretion of ExoU is critical during early Pseudomonas aeruginosa pneumonia","volume":"4","author":"Howell","year":"2013","journal-title":"mBio"},{"key":"10.1016\/j.jgar.2023.01.011_bib0026","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/nrmicro2199","article-title":"The type III secretion system of Pseudomonas aeruginosa: infection by injection","volume":"7","author":"Hauser","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.jgar.2023.01.011_bib0027","article-title":"IS26 veers genomic plasticity and genetic rearrangement toward carbapenem hyperresistance under sublethal antibiotics","volume":"13","author":"Wei","year":"2022","journal-title":"mBio"},{"key":"10.1016\/j.jgar.2023.01.011_bib0028","article-title":"A potential high-risk clone of Pseudomonas aeruginosa ST463","volume":"12","author":"Hu","year":"2021","journal-title":"Front Microbiol"}],"container-title":["Journal of Global Antimicrobial Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716523000152?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716523000152?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T10:00:34Z","timestamp":1761991234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213716523000152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":28,"alternative-id":["S2213716523000152"],"URL":"https:\/\/doi.org\/10.1016\/j.jgar.2023.01.011","relation":{},"ISSN":["2213-7165"],"issn-type":[{"value":"2213-7165","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characteristics of rare ST463 carbapenem-resistant Pseudomonas aeruginosa clinical isolates from blood","name":"articletitle","label":"Article Title"},{"value":"Journal of Global Antimicrobial Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgar.2023.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.","name":"copyright","label":"Copyright"}]}}