{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:17:56Z","timestamp":1790662676474,"version":"4.1.0"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Zhejiang Province Natural Science Foundation","doi-asserted-by":"publisher","award":["LQ20H200003"],"award-info":[{"award-number":["LQ20H200003"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017594","name":"Medical Science and Technology Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2023RC231"],"award-info":[{"award-number":["2023RC231"]}],"id":[{"id":"10.13039\/501100017594","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Global Antimicrobial Resistance"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.jgar.2025.02.009","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T11:26:16Z","timestamp":1739791576000},"page":"61-65","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["IS26-mediated cointegration generates a plasmid co-harbouring blaIMP-4 and blaKPC-2 in Klebsiella pneumoniae"],"prefix":"10.1016","volume":"42","author":[{"given":"Jiawei","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohua","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujun","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingjiao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgar.2025.02.009_bib0001","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/nyas.12537","article-title":"Carbapenem-resistant Enterobacteriaceae: biology, epidemiology, and management","volume":"1323","author":"Temkin","year":"2014","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jgar.2025.02.009_bib0002","doi-asserted-by":"crossref","first-page":"3341","DOI":"10.3389\/fmicb.2018.03341","article-title":"Genetic diversity of carbapenem-resistant Enterobacteriaceae (CRE) clinical isolates from a tertiary hospital in eastern China","volume":"9","author":"Miao","year":"2018","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jgar.2025.02.009_bib0003","doi-asserted-by":"crossref","first-page":"314","DOI":"10.3389\/fcimb.2020.00314","article-title":"Dissemination of carbapenemases (KPC, NDM, OXA-48, IMP, and VIM) among carbapenem-resistant Enterobacteriaceae isolated from adult and children patients in China","volume":"10","author":"Han","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jgar.2025.02.009_bib0004","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.1093\/jac\/dkv232","article-title":"Coexistence of a novel KPC-2-encoding MDR plasmid and an NDM-1-encoding pNDM-HN380-like plasmid in a clinical isolate of Citrobacter freundii","volume":"70","author":"Feng","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2025.02.009_bib0005","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1128\/AAC.03053-15","article-title":"Genomic characterization of Enterobacter cloacae isolates from China that coproduce KPC-3 and NDM-1 carbapenemases","volume":"60","author":"Du","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2025.02.009_bib0006","doi-asserted-by":"crossref","first-page":"e00877","DOI":"10.1128\/AAC.00877-17","article-title":"First report of Klebsiella oxytoca strain simultaneously producing NDM-1, IMP-4, and KPC-2 carbapenemases","volume":"61","author":"Wang","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2025.02.009_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2019.102599","article-title":"The transferability and evolution of NDM-1 and KPC-2 co-producing Klebsiella pneumoniae from clinical settings","volume":"51","author":"Gao","year":"2020","journal-title":"EBioMedicine"},{"key":"10.1016\/j.jgar.2025.02.009_bib0008","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1007\/s10096-011-1512-7","article-title":"Characterization of a novel Klebsiella pneumoniae sequence type 476 carrying both blaKPC-2 and blaIMP-4","volume":"31","author":"Wang","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.jgar.2025.02.009_bib0009","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02616-22","article-title":"Characterization of a conjugative hybrid plasmid coharboring blaKPC-2 and blaIMP-4 in a Klebsiella quasipneumoniae clinical isolate","volume":"11","author":"Dong","year":"2023","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.jgar.2025.02.009_bib0010","doi-asserted-by":"crossref","first-page":"3415","DOI":"10.2147\/IDR.S320294","article-title":"Emergence and genetic characterization of plasmid-encoded VIM-2-producing Pseudomonas stutzeri with novel integron In1998 isolated from cerebrospinal fluid","volume":"14","author":"Liu","year":"2021","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.jgar.2025.02.009_bib0011","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1074612","article-title":"Coexistence of blaIMP-4, blaNDM-1 and blaOXA-1 in blaKPC-2-producing Citrobacter freundii of clinical origin in China","volume":"14","author":"Qiao","year":"2023","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jgar.2025.02.009_bib0012","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1005595","article-title":"Unicycler: resolving bacterial genome assemblies from short and long sequencing reads","volume":"13","author":"Wick","year":"2017","journal-title":"PLoS Comput Biol"},{"key":"10.1016\/j.jgar.2025.02.009_bib0013","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1186\/1471-2164-12-402","article-title":"BLAST ring image generator (BRIG): simple prokaryote genome comparisons","volume":"12","author":"Alikhan","year":"2011","journal-title":"BMC Genomics"},{"key":"10.1016\/j.jgar.2025.02.009_bib0014","doi-asserted-by":"crossref","first-page":"e01983","DOI":"10.1128\/AAC.01983-19","article-title":"Emergence of KPC-2-producing Raoultella ornithinolytica isolated from a hospital wastewater treatment plant","volume":"64","author":"Chi","year":"2020","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2025.02.009_bib0015","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.2147\/IDR.S303739","article-title":"Epidemiological characterization of colistin and carbapenem resistant Enterobacteriaceae in a tertiary: a hospital from Anhui Province","volume":"14","author":"Hameed","year":"2021","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.jgar.2025.02.009_bib0016","doi-asserted-by":"crossref","first-page":"e00088","DOI":"10.1128\/CMR.00088-17","article-title":"Mobile genetic elements associated with antimicrobial resistance","volume":"31","author":"Partridge","year":"2018","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jgar.2025.02.009_bib0017","doi-asserted-by":"crossref","first-page":"e00762","DOI":"10.1128\/mBio.00762-15","article-title":"Insertion sequence IS26 reorganizes plasmids in clinically esolated multidrug-resistant bacteria by replicative transposition","volume":"6","author":"He","year":"2015","journal-title":"MBio"},{"key":"10.1016\/j.jgar.2025.02.009_bib0018","doi-asserted-by":"crossref","first-page":"e01801","DOI":"10.1128\/mBio.01801-14","article-title":"Movement of IS26-associated antibiotic resistance genes occurs via a translocatable unit that includes a single IS26 and preferentially inserts adjacent to another IS26","volume":"5","author":"Harmer","year":"2014","journal-title":"MBio"},{"key":"10.1016\/j.jgar.2025.02.009_bib0019","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/nrmicro2319","article-title":"Antibiotic resistance and its cost: is it possible to reverse resistance?","volume":"8","author":"Andersson","year":"2010","journal-title":"Nat Rev Microbiol"}],"container-title":["Journal of Global Antimicrobial Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716525000402?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716525000402?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T08:48:25Z","timestamp":1746607705000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213716525000402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":19,"alternative-id":["S2213716525000402"],"URL":"https:\/\/doi.org\/10.1016\/j.jgar.2025.02.009","relation":{},"ISSN":["2213-7165"],"issn-type":[{"value":"2213-7165","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"IS26-mediated cointegration generates a plasmid co-harbouring blaIMP-4 and blaKPC-2 in Klebsiella pneumoniae","name":"articletitle","label":"Article Title"},{"value":"Journal of Global Antimicrobial Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgar.2025.02.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.","name":"copyright","label":"Copyright"}]}}