{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:59:13Z","timestamp":1790391553100,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["P E00000007"],"award-info":[{"award-number":["P E00000007"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["PRJNA1257561"],"award-info":[{"award-number":["PRJNA1257561"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Global Antimicrobial Resistance"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.jgar.2025.11.007","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T02:59:17Z","timestamp":1763693957000},"page":"87-97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Emergence and inter-hospital circulation of capsule K2- and OXA-48-producing Klebsiella pneumoniae ST395 in north-eastern Italy"],"prefix":"10.1016","volume":"46","author":[{"given":"Vittoria","family":"Mattioni Marchetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6188-3568","authenticated-orcid":false,"given":"Francesca","family":"Piscopiello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assunta","family":"Girardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2952-9825","authenticated-orcid":false,"given":"Stefano","family":"Grandesso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Migliavacca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgar.2025.11.007_bib0001","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13073-023-01159-6","article-title":"Genomic analysis of the international high-risk clonal lineage Klebsiella pneumoniae sequence type 395","volume":"15","author":"Shaidullina","year":"2023","journal-title":"Genome Med"},{"key":"10.1016\/j.jgar.2025.11.007_bib0002","first-page":"381","article-title":"Evaluation of potential factors influencing the dissemination of multidrug-resistant Klebsiella pneumoniae and alternative treatment strategies","volume":"8","author":"Ndlovu","year":"2023","journal-title":"Trop Med Infect Dis"},{"key":"10.1016\/j.jgar.2025.11.007_bib0003","doi-asserted-by":"crossref","DOI":"10.1016\/j.microb.2025.100289","article-title":"Virulence factors of Klebsiella pneumoniae: insights into canonical and emerging mechanisms driving pathogenicity and drug resistance","volume":"7","author":"Singh","year":"2025","journal-title":"Microbe"},{"key":"10.1016\/j.jgar.2025.11.007_bib0004","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00776-18","article-title":"Identification of biomarkers for differentiation of hypervirulent Klebsiella pneumoniae from classical K. pneumoniae","volume":"56","author":"Russo","year":"2018","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1010693","article-title":"Capsule type defines the capability of Klebsiella pneumoniae in evading Kupffer cell capture in the liver","volume":"18","author":"Huang","year":"2022","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.jgar.2025.11.007_bib0006","article-title":"Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population","volume":"6","author":"Lee","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.jgar.2025.11.007_bib0007","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01148-20","article-title":"Emerging antimicrobial-resistant high-risk Klebsiella pneumoniae clones ST307 and ST147","volume":"64","author":"Peirano","year":"2020","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2025.11.007_bib0008","doi-asserted-by":"crossref","first-page":"7494","DOI":"10.1128\/AAC.00525-16","article-title":"Outbreak of OXA-48-producing Klebsiella pneumoniae involving a sequence type 101 clone in Batna University Hospital, Algeria","volume":"60","author":"Loucif","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2025.11.007_bib0009","doi-asserted-by":"crossref","DOI":"10.1111\/j.1469-0691.2011.03669.x","article-title":"European dissemination of a single OXA-48-producing Klebsiella pneumoniae clone","volume":"17","author":"Potron","year":"2011","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.jgar.2025.11.007_bib0010","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/23744235.2016.1207252","article-title":"Emergence and interhospital spread of OXA-48-producing Klebsiella pneumoniae ST395 clone in western Hungary","volume":"49","author":"Kov\u00e1cs","year":"2017","journal-title":"Infect Dis"},{"key":"10.1016\/j.jgar.2025.11.007_bib0011","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.1128\/AAC.00086-15","article-title":"Prospective multicenter study of carbapenemase-producing Enterobacteriaceae from 83 hospitals in Spain reveals high in vitro susceptibility to colistin and meropenem","volume":"59","author":"Oteo","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2025.11.007_bib0012","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01889-16","article-title":"Molecular characterization of OXA-48-like-producing Enterobacteriaceae in the Czech Republic and evidence for horizontal transfer of pOXA-48-like plasmids","volume":"61","author":"Skalova","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgar.2025.11.007_bib0013","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1093\/jac\/dkaa431","article-title":"The changing epidemiology of carbapenemase-producing Klebsiella pneumoniae in Italy: toward polyclonal evolution with emergence of high-risk lineages","volume":"76","author":"Di Pilato","year":"2021","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.jgar.2025.11.007_bib0014","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1017\/ice.2017.267","article-title":"Outbreak of ST395 KPC-producing Klebsiella pneumoniae in a neonatal intensive care unit in Palermo, Italy","volume":"39","author":"Maida","year":"2018","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0015","doi-asserted-by":"crossref","first-page":"6220","DOI":"10.1038\/s41598-024-55884-y","article-title":"Enterobacter asburiae ST229: an emerging carbapenemase producer","volume":"14","author":"Mattioni Marchetti","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.jgar.2025.11.007_bib0016","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2025.1519827","article-title":"Polyclonal carbapenemase-producing Escherichia coli in northern Italy: the emergence of NDM-7","volume":"15","author":"Mattioni Marchetti","year":"2025","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0017","doi-asserted-by":"crossref","first-page":"omac035","DOI":"10.1093\/omcr\/omac035","article-title":"Positive string test in hypervirulent Klebsiella pneumoniae liver abscess","volume":"2022","author":"Chang","year":"2022","journal-title":"Oxf Med Case Rep"},{"key":"10.1016\/j.jgar.2025.11.007_bib0018","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4161\/viru.22718","article-title":"Hypervirulent (hypermucoviscous) Klebsiella pneumoniae: a new and dangerous breed","volume":"4","author":"Shon","year":"2013","journal-title":"Virulence"},{"key":"10.1016\/j.jgar.2025.11.007_bib0019","article-title":"Antibiotic resistance and novel sequence types of Klebsiella spp. in human, animal, and food sources: a One Health perspective from northern Nigeria","volume":"9","author":"Adesoji","year":"2025","journal-title":"Curr Res Microb Sci"},{"key":"10.1016\/j.jgar.2025.11.007_bib0020","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.diagmicrobio.2012.11.014","article-title":"Nunes AP. Modification of the Congo red agar method to detect biofilm production by Staphylococcus epidermidis","volume":"75","author":"Kaiser","year":"2013","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.jgar.2025.11.007_bib0021","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1128\/AEM.00261-08","article-title":"Oxygen-mediated regulation of biofilm development is controlled by the alternative sigma factor sigma(B) in Staphylococcus epidermidis","volume":"75","author":"Cotter","year":"2009","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0022","doi-asserted-by":"crossref","first-page":"3382","DOI":"10.3168\/jds.2024-25416","article-title":"Biofilm-forming ability of Staphylococcus aureus on materials commonly found in milking-equipment surfaces","volume":"108","author":"Medina","year":"2025","journal-title":"J Dairy Sci"},{"key":"10.1016\/j.jgar.2025.11.007_bib0023","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1128\/jcm.33.9.2233-2239.1995","article-title":"Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing","volume":"33","author":"Tenover","year":"1995","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0024","doi-asserted-by":"crossref","first-page":"4188","DOI":"10.1038\/s41467-021-24448-3","article-title":"A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex","volume":"12","author":"Lam","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.jgar.2025.11.007_bib0025","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1093\/molbev\/mst028","article-title":"Hierarchical and spatially explicit clustering of DNA sequences with BAPS software","volume":"30","author":"Cheng","year":"2013","journal-title":"Mol Biol Evol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0026","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.3390\/microorganisms8081232","article-title":"Genomic insight of VIM-harbouring IncA plasmid from a clinical ST69 Escherichia coli strain in Italy","volume":"8","author":"Mattioni Marchetti","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.jgar.2025.11.007_bib0027","first-page":"230","article-title":"Detection of ST1702 Escherichia coli blaNDM-5 and blaCMY-42 positive isolates from a northern Italian hospital","volume":"41","author":"Piazza","year":"2018","journal-title":"New Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0028","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.3389\/fmicb.2019.02119","article-title":"Antibiotic-induced increased conjugative transfer is common to diverse naturally occurring ESBL plasmids in Escherichia coli","volume":"10","author":"Liu","year":"2019","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0029","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.jgar.2017.10.023","article-title":"Spread of Klebsiella pneumoniae ST395 non-susceptible to carbapenems and resistant to fluoroquinolones in north-eastern France","volume":"13","author":"Muggeo","year":"2018","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.jgar.2025.11.007_bib0030","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3390\/microorganisms13010089","article-title":"Sequencing analysis of invasive carbapenem-resistant Klebsiella pneumoniae isolates secondary to gastrointestinal colonization","volume":"13","author":"Maugeri","year":"2025","journal-title":"Microorganisms"},{"key":"10.1016\/j.jgar.2025.11.007_bib0031","article-title":"Epidemiological and biological characteristics of IncR plasmids as multihost antibiotic resistance carriers","volume":"16","author":"Zhang","year":"2025","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0032","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jgar.2023.04.018","article-title":"Analysis of an IncR plasmid carried by carbapenem-resistant Klebsiella pneumoniae: a survey of swine Klebsiella pneumoniae in Jilin Province","volume":"34","author":"Qi","year":"2023","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.jgar.2025.11.007_bib0033","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.781127","article-title":"Clonal spread and intra- and inter-species plasmid dissemination associated with Klebsiella pneumoniae carbapenemase-producing Enterobacterales during a hospital outbreak in Barcelona, Spain","volume":"12","author":"Mar\u00ed-Almirall","year":"2021","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0034","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.03519-23","article-title":"Klebsiella pneumoniae K2 capsular polysaccharide degradation by a bacteriophage depolymerase does not require trimer formation","volume":"15","author":"Ye","year":"2024","journal-title":"mBio"},{"key":"10.1016\/j.jgar.2025.11.007_bib0035","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1128\/JCM.01150-06","article-title":"Capsular serotype K1 or K2, rather than magA and rmpA, is a major virulence determinant for Klebsiella pneumoniae liver abscess in Singapore and Taiwan","volume":"45","author":"Yeh","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jgar.2025.11.007_bib0036","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1128\/iai.63.3.847-852.1995","article-title":"Relationships among capsular structure, phagocytosis, and mouse virulence in Klebsiella pneumoniae","volume":"63","author":"Kabha","year":"1995","journal-title":"Infect Immun"},{"key":"10.1016\/j.jgar.2025.11.007_bib0037","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.micinf.2004.06.003","article-title":"High prevalence of phagocytic-resistant capsular serotypes of Klebsiella pneumoniae in liver abscess","volume":"6","author":"Lin","year":"2004","journal-title":"Microbes Infect"},{"key":"10.1016\/j.jgar.2025.11.007_bib0038","doi-asserted-by":"crossref","first-page":"673","DOI":"10.4161\/viru.32076","article-title":"Sialic acid involved in hypermucoviscosity phenotype of Klebsiella pneumoniae and associated with resistance to neutrophil phagocytosis","volume":"5","author":"Lee","year":"2014","journal-title":"Virulence"},{"key":"10.1016\/j.jgar.2025.11.007_bib0039","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1128\/MMBR.00078-15","article-title":"Klebsiella pneumoniae: going on the offense with a strong defense","volume":"80","author":"Paczosa","year":"2016","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1016\/j.jgar.2025.11.007_bib0040","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0378-1097(99)00636-9","article-title":"Association of qacE and qacE\u03941 with multiple resistance to antibiotics and antiseptics in clinical isolates of Gram-negative bacteria","volume":"183","author":"K\u00fccken","year":"2000","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.jgar.2025.11.007_bib0041","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1556\/EuJMI-D-14-00038","article-title":"Ingmer H. Review and phylogenetic analysis of qac genes that reduce susceptibility to quaternary ammonium compounds in Staphylococcus species","volume":"5","author":"Wassenaar","year":"2015","journal-title":"Eur J Microbiol Immunol"},{"issue":"1","key":"10.1016\/j.jgar.2025.11.007_bib42","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s10238-025-01950-2","article-title":"Disinfectant-induced bacterial resistance and antibiotic cross-resistance-mechanisms and clinical relevance","volume":"26","author":"Walczak","year":"2025","journal-title":"Clin Exp Med"}],"container-title":["Journal of Global Antimicrobial Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716525002486?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716525002486?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T07:51:28Z","timestamp":1781509888000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213716525002486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":42,"alternative-id":["S2213716525002486"],"URL":"https:\/\/doi.org\/10.1016\/j.jgar.2025.11.007","relation":{},"ISSN":["2213-7165"],"issn-type":[{"value":"2213-7165","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emergence and inter-hospital circulation of capsule K2- and OXA-48-producing Klebsiella pneumoniae ST395 in north-eastern Italy","name":"articletitle","label":"Article Title"},{"value":"Journal of Global Antimicrobial Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgar.2025.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.","name":"copyright","label":"Copyright"}]}}