{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:08:20Z","timestamp":1790179700778,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2026NSFSC1549"],"award-info":[{"award-number":["2026NSFSC1549"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Global Antimicrobial Resistance"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jgar.2026.07.026","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:36:43Z","timestamp":1786034203000},"page":"479-487","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Metagenomic next-generation sequencing (mNGS) for detecting pathogens and antimicrobial resistance genes (ARGs), and guiding antimicrobial therapy in cancer patients from Southwest China"],"prefix":"10.1016","volume":"50","author":[{"given":"Qian","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan-ling","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jgar.2026.07.026_bib0001","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1086\/518873","article-title":"Polymicrobial infection in patients with cancer: an underappreciated and underreported entity","volume":"45","author":"Rolston","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jgar.2026.07.026_bib0002","doi-asserted-by":"crossref","first-page":"1388765","DOI":"10.3389\/fcimb.2024.1388765","article-title":"Metagenomic next-generation sequencing promotes pathogen detection over culture in joint infections with previous antibiotic exposure","volume":"14","author":"Gao","year":"2024","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jgar.2026.07.026_bib0003","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/s13027-023-00556-1","article-title":"Pneumocystis jirovecii with high probability detected in bronchoalveolar lavage fluid of chemotherapy-related interstitial pneumonia in patients with lymphoma using metagenomic next-generation sequencing technology","volume":"18","author":"Jin","year":"2023","journal-title":"Infect Agents Cancer"},{"key":"10.1016\/j.jgar.2026.07.026_bib0004","article-title":"Case report: diagnosis of Human alveolar echinococcosis via next-generation sequencing analysis","volume":"12","author":"Li","year":"2021","journal-title":"Front Genet"},{"key":"10.1016\/j.jgar.2026.07.026_bib0005","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.687984","article-title":"Case report: metagenomic next-generation sequencing in diagnosis of disseminated tuberculosis of an immunocompetent patient","volume":"8","author":"Ye","year":"2021","journal-title":"Front Med"},{"key":"10.1016\/j.jgar.2026.07.026_bib0006","doi-asserted-by":"crossref","DOI":"10.1186\/s12890-022-02227-0","article-title":"Disseminated nontuberculous mycobacterial infection with cryptic immunodeficiency mimicking malignancy: a case report","volume":"22","author":"Sun","year":"2022","journal-title":"BMC Pulm Med"},{"issue":"1","key":"10.1016\/j.jgar.2026.07.026_bib0007","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1146\/annurev-pathmechdis-012418-012751","article-title":"Clinical metagenomic next-generation sequencing for pathogen detection","volume":"14","author":"Gu","year":"2019","journal-title":"Annu Rev Pathol: Mech Dis"},{"key":"10.1016\/j.jgar.2026.07.026_bib0008","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2024.1458316","article-title":"Application of metagenomic next-generation sequencing in the diagnosis of infectious diseases","volume":"14","author":"Zhao","year":"2024","journal-title":"Front Cell Infect Microbiol"},{"issue":"4","key":"10.1016\/j.jgar.2026.07.026_bib0009","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1097\/QCO.0000000000000936","article-title":"Sequence-based diagnostics and precision medicine in bacterial and viral infections: from bench to bedside","volume":"36","author":"Pham","year":"2023","journal-title":"Curr Opin Infect Dis"},{"key":"10.1016\/j.jgar.2026.07.026_bib0010","doi-asserted-by":"crossref","DOI":"10.1186\/s12931-023-02654-5","article-title":"Clinical application of bronchoalveolar lavage fluid metagenomics next-generation sequencing in cancer patients with severe pneumonia","volume":"25","author":"Wang","year":"2024","journal-title":"Respir Res"},{"issue":"8","key":"10.1016\/j.jgar.2026.07.026_bib0011","doi-asserted-by":"crossref","first-page":"ofac393","DOI":"10.1093\/ofid\/ofac393","article-title":"Pathogen detection by metagenomic next-generation sequencing during neutropenic fever in patients with hematological malignancies","volume":"9","author":"Schulz","year":"2022","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.jgar.2026.07.026_bib0012","article-title":"Nasal and cutaneous mucormycosis in two patients with lymphoma after chemotherapy and target therapy: early detection by metagenomic next-generation sequencing","volume":"12","author":"Zhang","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jgar.2026.07.026_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.cca.2025.120478","article-title":"Targeted next-generation sequencing of bronchoalveolar-lavage fluid specimens in the diagnosis of pulmonary infection after hematopoietic stem cell transplantation","volume":"577","author":"Xiao","year":"2025","journal-title":"Clin Chim Acta"},{"issue":"24","key":"10.1016\/j.jgar.2026.07.026_bib0014","doi-asserted-by":"crossref","first-page":"12685","DOI":"10.18632\/aging.102595","article-title":"Combination of lymphocyte number and function in evaluating host immunity","volume":"11","author":"Luo","year":"2019","journal-title":"AGING"},{"key":"10.1016\/j.jgar.2026.07.026_bib0015","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.2147\/IDR.S364525","article-title":"The value of metagenomic next-generation sequencing in hematological malignancy patients with febrile neutropenia after empiric antibiotic treatment failure","volume":"15","author":"Zhang","year":"2022","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.jgar.2026.07.026_bib0016","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.cca.2022.10.008","article-title":"Metagenomic next-generation sequencing for the diagnosis of fever of unknown origin in pediatric patients with hematological malignancy","volume":"537","author":"Zhang","year":"2022","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.jgar.2026.07.026_bib0017","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2024.1518199","article-title":"Metagenomic next-generation sequencing for lung cancer low respiratory tract infections diagnosis and characterizing microbiome features","volume":"14","author":"Liu","year":"2025","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jgar.2026.07.026_bib0018","doi-asserted-by":"crossref","DOI":"10.1186\/s12890-023-02681-4","article-title":"Pathogen distribution in pulmonary infection in chinese patients with lung cancer: a systematic review and meta-analysis","volume":"23","author":"Wang","year":"2023","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.jgar.2026.07.026_bib0019","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.2147\/IDR.S491507","article-title":"The inter-relationships among the risk factors for pulmonary infection and the diagnostic utility of inflammatory markers in patients with non-small cell lung cancer","volume":"18","author":"Qin","year":"2025","journal-title":"Infect Drug Resist"},{"issue":"7","key":"10.1016\/j.jgar.2026.07.026_bib0020","doi-asserted-by":"crossref","first-page":"106903","DOI":"10.4239\/wjd.v16.i7.106903","article-title":"Risk factors for pulmonary infection after thoracoscopic radical resection of lung cancer in elderly patients with diabetes mellitus","volume":"16","author":"Chen","year":"2025","journal-title":"World J Diabetes"},{"key":"10.1016\/j.jgar.2026.07.026_bib0021","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-021-06243-z","article-title":"Bloodstream infections in adult patients with malignancy, epidemiology, microbiology, and risk factors associated with mortality and multi-drug resistance","volume":"21","author":"Amanati","year":"2021","journal-title":"BMC Infect Dis"},{"issue":"2","key":"10.1016\/j.jgar.2026.07.026_bib0022","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s15010-024-02185-1","article-title":"Utilizing metagenomic next-generation sequencing for pathogen detection and diagnosis in lower respiratory tract infections in real-world clinical practice","volume":"52","author":"Lv","year":"2024","journal-title":"Infection"},{"issue":"6","key":"10.1016\/j.jgar.2026.07.026_bib0023","doi-asserted-by":"crossref","first-page":"488","DOI":"10.3322\/caac.21697","article-title":"Antibiotic resistance in the patient with cancer: escalating challenges and paths forward. CA: a","volume":"71","author":"Nanayakkara","year":"2021","journal-title":"Cancer J Clin"},{"key":"10.1016\/j.jgar.2026.07.026_bib0024","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-025-10481-w","article-title":"Antimicrobial resistance of bacterial pathogens isolated from cancer patients: a systematic review and meta-analysis","volume":"25","author":"Ntim","year":"2025","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.jgar.2026.07.026_bib0025","doi-asserted-by":"crossref","DOI":"10.1186\/s12941-024-00703-5","article-title":"Investigation of antimicrobial susceptibility patterns, risk factors and their impact on mortality in cancer patients at a tertiary care cancer hospital- a prospective study","volume":"23","author":"Shelke","year":"2024","journal-title":"Ann Clin Microbiol Antimicrob"},{"issue":"10","key":"10.1016\/j.jgar.2026.07.026_bib0026","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02961-23","article-title":"Prevalence and impact of multidrug-resistant bacteria in solid cancer patients with bloodstream infection: a 25-year trend analysis","volume":"12","author":"Lopera","year":"2024","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.jgar.2026.07.026_bib0027","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2025.1521641","article-title":"The impact of bronchoalveolar lavage fluid metagenomics next-generation sequencing on the diagnosis and management of patients with suspected pulmonary infection","volume":"15","author":"Zhou","year":"2025","journal-title":"Front Cell Infect Microbiol"},{"issue":"3","key":"10.1016\/j.jgar.2026.07.026_bib0028","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1200\/PO.18.00356","article-title":"Economic impact of next-generation sequencing versus single-gene testing to detect genomic alterations in metastatic non\u2013Small-cell lung cancer using a decision analytic model","author":"Pennell","year":"2019","journal-title":"JCO Precis Oncol"},{"key":"10.1016\/j.jgar.2026.07.026_bib0029","article-title":"Risk factors and clinical characteristics of Pneumocystis jirovecii pneumonia in lung cancer","volume":"9","author":"Lee","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.jgar.2026.07.026_bib0030","doi-asserted-by":"crossref","DOI":"10.1186\/s12890-022-02300-8","article-title":"Risk factors associated with Pneumocystis jirovecii pneumonia in non-HIV immunocompromised patients and co-pathogens analysis by metagenomic next-generation sequencing","volume":"23","author":"Huang","year":"2023","journal-title":"BMC Pulm Med"},{"key":"10.1016\/j.jgar.2026.07.026_bib0031","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-021-08727-2","article-title":"Clinical characteristics and risk factors associated with Pneumocystis jirovecii infection in patients with solid tumors: study of thirteen-year medical records of a large cancer center","volume":"21","author":"Takeda","year":"2021","journal-title":"BMC Cancer"},{"issue":"3","key":"10.1016\/j.jgar.2026.07.026_bib0032","doi-asserted-by":"crossref","first-page":"302","DOI":"10.2174\/1871530319666190211163245","article-title":"Invasive fungal infection in febrile patients with hematologic malignancies undergoing chemotherapy in Iran","volume":"19","author":"Sheikhbahaei","year":"2019","journal-title":"Endocr Metab Immune Disord - Drug Targets"}],"container-title":["Journal of Global Antimicrobial Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716526001335?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213716526001335?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:52:47Z","timestamp":1790178767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213716526001335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":32,"alternative-id":["S2213716526001335"],"URL":"https:\/\/doi.org\/10.1016\/j.jgar.2026.07.026","relation":{},"ISSN":["2213-7165"],"issn-type":[{"value":"2213-7165","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metagenomic next-generation sequencing (mNGS) for detecting pathogens and antimicrobial resistance genes (ARGs), and guiding antimicrobial therapy in cancer patients from Southwest China","name":"articletitle","label":"Article Title"},{"value":"Journal of Global Antimicrobial Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgar.2026.07.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.","name":"copyright","label":"Copyright"}]}}