{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T12:10:38Z","timestamp":1789560638096,"version":"build-2803163510"},"reference-count":99,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetic Engineering and Biotechnology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jgeb.2026.100714","type":"journal-article","created":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T21:16:13Z","timestamp":1780348573000},"page":"100714","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence and antibiotic resistance pattern of Staphylococcus spp. isolated from acne, and disrupting their antimicrobial resistance: unveiling the potential of Ganoderma lucidum extract"],"prefix":"10.1016","volume":"24","author":[{"given":"Md. Mainuddin","family":"Hossain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juthi","family":"Adhikari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Sharif","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadia Binta","family":"Based","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Dutta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatama Tous","family":"Zohora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu Zaffar","family":"Shibly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgeb.2026.100714_bb0005","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.f2634","article-title":"Acne vulgaris","volume":"346","author":"Dawson","year":"2013","journal-title":"BMJ"},{"key":"10.1016\/j.jgeb.2026.100714_bb0010","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2023.1152391","article-title":"The management of acne vulgaris in young people in primary care: a retrospective cohort study","volume":"10","author":"Moosa","year":"2023","journal-title":"Front Med"},{"key":"10.1016\/j.jgeb.2026.100714_bb0015","first-page":"525","article-title":"Presentation and management of acne in primary care: a retrospective cohort study","volume":"53","author":"Purdy","year":"2003","journal-title":"Br J Gen Pract J R Coll Gen Pract"},{"key":"10.1016\/j.jgeb.2026.100714_bb0020","doi-asserted-by":"crossref","first-page":"328","DOI":"10.4103\/ijd.IJD_565_17","article-title":"Factors aggravating or precipitating acne in Indian adults: a hospital-based study of 110 cases","volume":"63","author":"George","year":"2018","journal-title":"Indian J Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0025","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1440-0960.1997.tb01126.x","article-title":"Descriptive epidemiology of acne vulgaris in the community","volume":"38","author":"Stathakis","year":"1997","journal-title":"Australas J Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0030","first-page":"13","article-title":"The epidemiology of acne vulgaris in late adolescence","volume":"7","author":"Lynn","year":"2016","journal-title":"Adolesc Health Med Ther"},{"key":"10.1016\/j.jgeb.2026.100714_bb0035","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/dth.12108","article-title":"Evaluation and treatment of acne from infancy to preadolescence","volume":"26","author":"Admani","year":"2013","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.jgeb.2026.100714_bb0040","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1365-2133.2008.08437.x","article-title":"Skin microbiota: a source of disease or defence?","volume":"158","author":"Cogen","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0045","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3329\/bpj.v18i2.24309","article-title":"Antibiotic sensitivity of Staphylococcus aureus and Staphylococcus epidermidis isolated from acne patients","volume":"18","author":"Khan","year":"2015","journal-title":"Bangladesh Pharm J"},{"key":"10.1016\/j.jgeb.2026.100714_bb0050","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1128\/CMR.00134-14","article-title":"Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management","volume":"28","author":"Tong","year":"2015","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jgeb.2026.100714_bb0055","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1517\/14728214.2015.990373","article-title":"Emerging drugs for the treatment of acne","volume":"20","author":"Aslam","year":"2015","journal-title":"Expert Opin Emerg Drugs"},{"key":"10.1016\/j.jgeb.2026.100714_bb0060","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s40257-014-0099-z","article-title":"Recent advances in acne pathogenesis: implications for therapy","volume":"15","author":"Das","year":"2014","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0065","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s40257-013-0042-8","article-title":"Immunotherapy for acne vulgaris: current status and future directions","volume":"14","author":"Simonart","year":"2013","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0070","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0002-9610(88)80545-2","article-title":"Morbidity and mortality of an endemic pathogen: methicillin-resistant Staphylococcus aureus","volume":"156","author":"Hunt","year":"1988","journal-title":"Am J Surg"},{"key":"10.1016\/j.jgeb.2026.100714_bb0075","doi-asserted-by":"crossref","first-page":"5754","DOI":"10.1038\/s41598-020-62715-3","article-title":"Systematic review of the epidemiology of acne vulgaris","volume":"10","author":"Heng","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.jgeb.2026.100714_bb0080","doi-asserted-by":"crossref","first-page":"71R","DOI":"10.1203\/PDR.0b013e31819dc44d","article-title":"Molecular pathogenesis of Staphylococcus aureus infection","volume":"65","author":"Liu","year":"2009","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jgeb.2026.100714_bb0085","first-page":"177","article-title":"The effect of personal, familial, and environmental characteristics on acne vulgaris: a prospective, multicenter, case controlled study","volume":"154","author":"Karada\u011f","year":"2019","journal-title":"G Ital di dermatologia e Venereol organo Uff Soc Ital di dermatologia e Sifilogr"},{"key":"10.1016\/j.jgeb.2026.100714_bb0090","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1111\/j.1468-3083.2011.04329.x","article-title":"Acne: prevalence and relationship with dietary habits in Eskisehir, Turkey","volume":"26","author":"Aksu","year":"2012","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0095","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.jaad.2012.02.018","article-title":"Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults","volume":"67","author":"Di Landro","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0100","first-page":"5","article-title":"Obese\/overweight and the risk of acne vulgaris in Chinese adolescents and young adults","volume":"25","author":"Lu","year":"2017","journal-title":"Hong Kong J Dermatol Venereol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0105","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3109\/09546634.2015.1061184","article-title":"Risk factors, psychological impacts and current treatments of acne in Shanghai area of China","volume":"27","author":"Wang","year":"2016","journal-title":"J Dermatolog Treat"},{"key":"10.1016\/j.jgeb.2026.100714_bb0110","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/jid.2010.264","article-title":"Suicidal ideation, mental health problems, and social impairment are increased in adolescents with acne: a population-based study","volume":"131","author":"Halvorsen","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0115","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/j.1440-1754.2006.00979.x","article-title":"Acne, anxiety, depression and suicide in teenagers: a cross-sectional survey of New Zealand secondary school students","volume":"42","author":"Purvis","year":"2006","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jgeb.2026.100714_bb0120","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/14728214.2022.2110239","article-title":"Emerging drugs for the treatment of acne: a review of phase 2 & 3 trials","volume":"27","author":"Bhatt","year":"2022","journal-title":"Expert Opin Emerg Drugs"},{"key":"10.1016\/j.jgeb.2026.100714_bb0125","first-page":"475","article-title":"Acne vulgaris: diagnosis and treatment","volume":"100","author":"Oge","year":"2019","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.jgeb.2026.100714_bb0130","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1517\/14656566.6.3.409","article-title":"Acne vulgaris: a review of antibiotic therapy","volume":"6","author":"Tan","year":"2005","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.jgeb.2026.100714_bb0135","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2025.1565111","article-title":"Antibiotic resistance rates in Cutibacterium acnes isolated from patients with acne vulgaris: a systematic review and meta-analysis","volume":"16","author":"Zhu","year":"2025","journal-title":"Front Microbiol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0140","doi-asserted-by":"crossref","DOI":"10.3390\/antibiotics12010145","article-title":"Microbiomes in acne vulgaris and their susceptibility to antibiotics in Indonesia: a systematic review and meta-analysis","volume":"12","author":"Legiawati","year":"2023","journal-title":"Antibiotics"},{"key":"10.1016\/j.jgeb.2026.100714_bb0145","doi-asserted-by":"crossref","first-page":"377","DOI":"10.36347\/sajp.2024.v13i09.001","article-title":"Antibiotic resistance in acne treatment: emerging challenges and implications for dermatology practice in developing countries like Bangladesh","volume":"9","author":"Begum","year":"2024","journal-title":"Sch Acad J Pharm"},{"key":"10.1016\/j.jgeb.2026.100714_bb0150","first-page":"277","article-title":"The antibiotic resistance crisis: part 1: causes and threats","volume":"40","author":"Ventola","year":"2015","journal-title":"P T"},{"key":"10.1016\/j.jgeb.2026.100714_bb0155","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1111\/j.1365-2133.1992.tb00104.x","article-title":"Antibiotic resistance patterns in coagulase-negative staphylococci after treatment with topical erythromycin, benzoyl peroxide, and combination therapy","volume":"126","author":"Harkaway","year":"1992","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0160","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1021\/acs.jnatprod.9b01285","article-title":"Natural products as sources of new drugs over the nearly four decades from 01\/1981 to 09\/2019","volume":"83","author":"Newman","year":"2020","journal-title":"J Nat Prod"},{"key":"10.1016\/j.jgeb.2026.100714_bb0165","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.lwt.2015.03.040","article-title":"Chemical composition, antioxidant activity and bioaccessibility studies in phenolic extracts of two Hericium wild edible species","volume":"63","author":"Heleno","year":"2015","journal-title":"LWT-Food Sci Technol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0170","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1016\/S0031-9422(98)00254-4","article-title":"Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum","volume":"49","author":"El-Mekkawy","year":"1998","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jgeb.2026.100714_bb0175","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/BF02979122","article-title":"Antimicrobial activity of Ganoderma lucidum extract alone and in combination with some antibiotics","volume":"17","author":"Yoon","year":"1994","journal-title":"Arch Pharm Res"},{"key":"10.1016\/j.jgeb.2026.100714_bb0180","doi-asserted-by":"crossref","first-page":"31272","DOI":"10.1038\/s41598-025-06068-9","article-title":"Phytochemical analysis and antimicrobial activity of Ganoderma lucidum against selected bacteria and fungi of medical importance","volume":"15","author":"Solomon","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.jgeb.2026.100714_bb0185","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1093\/jpp\/rgae133","article-title":"Ganoderma lucidum triterpenoids investigating their role in medicinal applications and genomic protection","volume":"76","author":"Raza","year":"2024","journal-title":"J Pharm Pharmacol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0190","article-title":"Core elements of outpatient antibiotic stewardship","volume":"65","author":"Sanchez","year":"2016","journal-title":"MMWR Recommen Rep"},{"key":"10.1016\/j.jgeb.2026.100714_bb0195","first-page":"5","article-title":"Mannitol salt agar for the isolation of Staphylococcus aureus","author":"Aryal","year":"2016","journal-title":"Microbiol info"},{"key":"10.1016\/j.jgeb.2026.100714_bb0200","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens10020170","article-title":"Virulence factors in coagulase-negative staphylococci","volume":"10","author":"Fran\u00e7a","year":"2021","journal-title":"Pathogens"},{"key":"10.1016\/j.jgeb.2026.100714_bb0205","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20051215","article-title":"Coagulase-negative staphylococci Pathogenomics","volume":"20","author":"Argemi","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jgeb.2026.100714_bb0210","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1370\/afm.123","article-title":"Why we don\u2019t come: patient perceptions on no-shows","volume":"2","author":"Lacy","year":"2004","journal-title":"Ann Fam Med"},{"key":"10.1016\/j.jgeb.2026.100714_bb0215","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01864-19","article-title":"The Clinical and Laboratory Standards Institute subcommittee on antimicrobial susceptibility testing: background, organization, functions, and processes","volume":"58","author":"Weinstein","year":"2020","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0220","doi-asserted-by":"crossref","DOI":"10.5812\/jjm.11188","article-title":"Antibiotic susceptibility and mecA frequency in Staphylococcus epidermidis, isolated from intensive care unit patients","volume":"7","author":"Najar-Peerayeh","year":"2014","journal-title":"Jundishapur J Microbiol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0225","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.3168\/jds.2015-9931","article-title":"Presence of mecA-positive multidrug-resistant Staphylococcus epidermidis in bovine milk samples in Brazil","volume":"99","author":"Dos Santos","year":"2016","journal-title":"J Dairy Sci"},{"key":"10.1016\/j.jgeb.2026.100714_bb0230","series-title":"Antibiotic susceptibility pattern among Staphylococcus spp. with emphasis on detection of mecA gene in methicillin resistant Staphylococcus aureus isolates","author":"Rahimi","year":"2009"},{"key":"10.1016\/j.jgeb.2026.100714_bb0235","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1172\/JCI18535","article-title":"Antimicrobial resistance: the example of Staphylococcus aureus","volume":"111","author":"Lowy","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jgeb.2026.100714_bb0240","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/s41586-022-05583-3","article-title":"Structural basis of broad-spectrum \u03b2-lactam resistance in Staphylococcus aureus","volume":"613","author":"Alexander","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.jgeb.2026.100714_bb0245","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1699-0463.1995.tb01099.x","article-title":"Erm genes in erythromycin-resistant Staphylococcus aureus and coagulase-negative staphylococci","volume":"103","author":"Westh","year":"1995","journal-title":"APMIS"},{"key":"10.1016\/j.jgeb.2026.100714_bb0250","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1128\/AAC.44.2.231-238.2000","article-title":"Correlation between the resistance genotype determined by multiplex PCR assays and the antibiotic susceptibility patterns of Staphylococcus aureus and Staphylococcus epidermidis","volume":"44","author":"Martineau","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgeb.2026.100714_bb0255","doi-asserted-by":"crossref","DOI":"10.3390\/antibiotics12030503","article-title":"Inhibition of erythromycin and erythromycin-induced resistance among Staphylococcus aureus clinical isolates","volume":"12","author":"Mahfouz","year":"2023","journal-title":"Antibiotics"},{"key":"10.1016\/j.jgeb.2026.100714_bb0260","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1093\/nar\/gkg520","article-title":"SWISS-MODEL: an automated protein homology-modeling server","volume":"31","author":"Schwede","year":"2003","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgeb.2026.100714_bb0265","doi-asserted-by":"crossref","first-page":"W296","DOI":"10.1093\/nar\/gky427","article-title":"SWISS-MODEL: homology modelling of protein structures and complexes","volume":"46","author":"Waterhouse","year":"2018","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgeb.2026.100714_bb0270","doi-asserted-by":"crossref","first-page":"W407","DOI":"10.1093\/nar\/gkm290","article-title":"ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins","volume":"35","author":"Wiederstein","year":"2007","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgeb.2026.100714_bb0275","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1002\/pro.5560020916","article-title":"Verification of protein structures: patterns of nonbonded atomic interactions","volume":"2","author":"Colovos","year":"1993","journal-title":"Protein Sci"},{"key":"10.1016\/j.jgeb.2026.100714_bb0280","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1107\/S0021889892009944","article-title":"PROCHECK: a program to check the stereochemical quality of protein structures","volume":"26","author":"Laskowski","year":"1993","journal-title":"J Appl Cryst"},{"key":"10.1016\/j.jgeb.2026.100714_bb0285","first-page":"D271","article-title":"The RCSB protein data bank: integrative view of protein, gene and 3D structural information","volume":"45","author":"Rose","year":"2017","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgeb.2026.100714_bb0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.insi.2025.100095","article-title":"Deep learning, network pharmacology and computational simulation reveal multi-target therapeutic mechanisms of Vitis vinifera (grapes) compounds against Alzheimer\u2019s disease","author":"Hossain","year":"2025","journal-title":"In Silico Res Biomed"},{"key":"10.1016\/j.jgeb.2026.100714_bb0295","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/bib\/2.2.195","article-title":"Swiss-PDB viewer (deep view)","volume":"2","author":"Kaplan","year":"2001","journal-title":"Brief Bioinform"},{"key":"10.1016\/j.jgeb.2026.100714_bb0300","doi-asserted-by":"crossref","first-page":"3345","DOI":"10.1007\/s11030-025-11125-6","article-title":"Machine learning and cheminformatics-based identification of lichen-derived compounds targeting mutant PBP4R200L in Staphylococcus aureus","volume":"29","author":"Mathpal","year":"2025","journal-title":"Mol Divers"},{"key":"10.1016\/j.jgeb.2026.100714_bb0305","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.1021\/acs.jcim.1c00203","article-title":"AutoDock Vina 1.2.0: new docking methods, expanded force field, and Python bindings","volume":"61","author":"Eberhardt","year":"2021","journal-title":"J Chem Inf Model"},{"key":"10.1016\/j.jgeb.2026.100714_bb0310","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","article-title":"AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading","volume":"31","author":"Trott","year":"2010","journal-title":"J Comput Chem"},{"key":"10.1016\/j.jgeb.2026.100714_bb0315","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0332170","article-title":"Exploring Dolichos lablab compounds as potential inhibitors for fusion (F) protein of human metapneumovirus (HMPV): a systematic computational approach","volume":"20","author":"Hossain","year":"2025","journal-title":"PloS One"},{"key":"10.1016\/j.jgeb.2026.100714_bb0320","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1093\/bioinformatics\/bty707","article-title":"admetSAR 2.0: web-service for prediction and optimization of chemical ADMET properties","volume":"35","author":"Yang","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jgeb.2026.100714_bb0325","doi-asserted-by":"crossref","DOI":"10.1038\/srep42717","article-title":"SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules","volume":"7","author":"Daina","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jgeb.2026.100714_bb0330","doi-asserted-by":"crossref","first-page":"W469","DOI":"10.1093\/nar\/gkae254","article-title":"Deep-PK: deep learning for small molecule pharmacokinetic and toxicity prediction","volume":"52","author":"Myung","year":"2024","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jgeb.2026.100714_bb0335","doi-asserted-by":"crossref","first-page":"4066","DOI":"10.1021\/acs.jmedchem.5b00104","article-title":"pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures","volume":"58","author":"Pires","year":"2015","journal-title":"J Med Chem"},{"key":"10.1016\/j.jgeb.2026.100714_bb0340","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/jcb.25307","article-title":"A molecular docking and dynamics study to screen potent anti-staphylococcal compounds against Ceftaroline resistant MRSA","volume":"117","author":"Lavanya","year":"2016","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.jgeb.2026.100714_bb0345","series-title":"Proceedings of the 2006 ACM\/IEEE conference on supercomputing","first-page":"84","article-title":"Scalable algorithms for molecular dynamics simulations on commodity clusters","author":"Bowers","year":"2006"},{"key":"10.1016\/j.jgeb.2026.100714_bb0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.insi.2025.100117","article-title":"Integrative network pharmacology, molecular docking and network-based drug repurposing reveal therapeutic targets and repurposable drugs for obesity-associated type 2 diabetes mellitus","volume":"1","author":"Hossain","year":"2025","journal-title":"Silico Res Biomed"},{"key":"10.1016\/j.jgeb.2026.100714_bb0355","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/1096-987X(20010415)22:5<501::AID-JCC1021>3.0.CO;2-V","article-title":"A fast SHAKE algorithm to solve distance constraint equations for small molecules in molecular dynamics simulations","volume":"22","author":"Kr\u00e4utler","year":"2001","journal-title":"J Comput Chem"},{"key":"10.1016\/j.jgeb.2026.100714_bb0360","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0021-9991(77)90098-5","article-title":"Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes","volume":"23","author":"Ryckaert","year":"1977","journal-title":"J Comput Phys"},{"key":"10.1016\/j.jgeb.2026.100714_bb0365","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0331339","article-title":"Computational prediction of high-risk non-synonymous SNPs in human ApoE and their structural impact on amyloid-\u03b2 interaction in Alzheimer\u2019s disease pathogenesis","volume":"20","author":"Hossain","year":"2025","journal-title":"PloS One"},{"key":"10.1016\/j.jgeb.2026.100714_bb0370","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1021\/acs.jctc.7b00028","article-title":"How molecular size impacts RMSD applications in molecular dynamics simulations","volume":"13","author":"Sargsyan","year":"2017","journal-title":"J Chem Theory Comput"},{"key":"10.1016\/j.jgeb.2026.100714_bb0375","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/j.1432-1033.1987.tb11173.x","article-title":"Stereospecific assignments of side-chain protons and characterization of torsion angles in Eglin c","volume":"164","author":"Hyberts","year":"1987","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.jgeb.2026.100714_bb0380","article-title":"Chemical characterization and evaluation of antimicrobial properties of the wild medicinal mushroom Ganoderma lucidum growing in northern Moroccan forests","volume":"13","author":"Erbiai","year":"2023","journal-title":"Life Basel"},{"key":"10.1016\/j.jgeb.2026.100714_bb0385","doi-asserted-by":"crossref","first-page":"13384","DOI":"10.3390\/molecules200713384","article-title":"Molecular docking and structure-based drug design strategies","volume":"20","author":"Ferreira","year":"2015","journal-title":"Molecules"},{"key":"10.1016\/j.jgeb.2026.100714_bb0390","doi-asserted-by":"crossref","DOI":"10.1515\/amma-2016-0007","article-title":"Diet, smoking and family history as potential risk factors in acne vulgaris-a community-based study","volume":"62","author":"Al Hussein","year":"2016","journal-title":"Acta Medica Marisiensis"},{"key":"10.1016\/j.jgeb.2026.100714_bb0395","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/jocd.12431","article-title":"Relationship between acne vulgaris and cosmetic usage in Sri Lankan urban adolescent females","volume":"17","author":"Perera","year":"2018","journal-title":"J Cosmet Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0400","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1038\/jid.2009.47","article-title":"Prevalence, severity, and severity risk factors of acne in high school pupils: a community-based study","volume":"129","author":"Ghodsi","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0405","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1111\/bjd.12912","article-title":"Epidemiology and extracutaneous comorbidities of severe acne in adolescence: a U.S. population-based study","volume":"170","author":"Silverberg","year":"2014","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0410","doi-asserted-by":"crossref","first-page":"135","DOI":"10.2340\/00015555-0231","article-title":"Study of psychological stress, sebum production and acne vulgaris in adolescents","volume":"87","author":"Yosipovitch","year":"2007","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0415","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2023.1153101","article-title":"Effects of acne severity and acne-related quality of life on depressive symptoms among adolescents and young adults: a cross-sectional study in Bangladesh","volume":"14","author":"Tasneem","year":"2023","journal-title":"Front Psychol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0420","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3329\/pa.v29i4.41348","article-title":"Study on indiscriminate use of antibiotics in poultry feed and residues in broilers of Mymensingh city in Bangladesh","volume":"29","author":"Khan","year":"2018","journal-title":"Progress Agric"},{"key":"10.1016\/j.jgeb.2026.100714_bb0425","first-page":"55","article-title":"Bacterial flora of acne lesions in diagnostic material of the microbiology and immunology department, Pomeranian medical academy (PAM) in Szczecin","volume":"48","author":"Za\u0142uga","year":"1996","journal-title":"Med Dosw Mikrobiol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0430","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s13756-017-0243-7","article-title":"Resistance of Staphylococcus aureus to antimicrobial agents in Ethiopia: a meta-analysis","volume":"6","author":"Deyno","year":"2017","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.jgeb.2026.100714_bb0435","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/j.sjbs.2018.05.008","article-title":"Antibiotic-resistant Staphylococcus epidermidis isolated from patients and healthy students comparing with antibiotic-resistant bacteria isolated from pasteurized milk","volume":"26","author":"Eladli","year":"2019","journal-title":"Saudi J Biol Sci"},{"key":"10.1016\/j.jgeb.2026.100714_bb0440","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jsps.2022.01.013","article-title":"Patterns of antibiotic use, knowledge, and perceptions among different population categories: a comprehensive study based in Arabic countries","volume":"30","author":"Alsayed","year":"2022","journal-title":"Saudi Pharm J"},{"key":"10.1016\/j.jgeb.2026.100714_bb0445","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/1523-1747.ep12676385","article-title":"Laboratory induction and clinical occurrence of combined clindamycin and erythromycin resistance in Corynebacterium acnes","volume":"72","author":"Crawford","year":"1979","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0450","first-page":"9","article-title":"Clinical considerations in the treatment of acne vulgaris and other inflammatory skin disorders: focus on antibiotic resistance","volume":"79","author":"Leyden","year":"2007","journal-title":"Cutis"},{"key":"10.1016\/j.jgeb.2026.100714_bb0455","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1128\/AAC.40.11.2598","article-title":"Effects of topical erythromycin on ecology of aerobic cutaneous bacterial flora","volume":"40","author":"Vowels","year":"1996","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.jgeb.2026.100714_bb0460","doi-asserted-by":"crossref","first-page":"6155","DOI":"10.2147\/IDR.S429687","article-title":"Antimicrobial resistance patterns of Staphylococcus aureus and Enterococcus species at the Ethiopian Public Health Institute, Ethiopia: a five-year retrospective analysis","volume":"16","author":"Abdeta","year":"2023","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.jgeb.2026.100714_bb0465","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1017\/S0195941700067278","article-title":"Emergence of coagulase negative staphylococci as major nosocomial bloodstream pathogens","volume":"8","author":"Stillman","year":"1987","journal-title":"Infect Control"},{"key":"10.1016\/j.jgeb.2026.100714_bb0470","doi-asserted-by":"crossref","first-page":"289","DOI":"10.4081\/itjm.2016.794","article-title":"Reading and understanding an antibiogram","volume":"10","author":"Tascini","year":"2016","journal-title":"Ital J Med"},{"key":"10.1016\/j.jgeb.2026.100714_bb0475","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1080\/000155502320323216","article-title":"Bacterial resistance and therapeutic outcome following three months of topical acne therapy with 2% erythromycin gel versus its vehicle","volume":"82","author":"Mills","year":"2002","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0480","doi-asserted-by":"crossref","DOI":"10.9734\/jabb\/2023\/v26i11667","article-title":"Antioxidant and antimicrobial activity of a medicinal mushroom, Ganoderma lucidum","author":"Canpolat","year":"2023","journal-title":"J Adv Biol Biotechnol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0485","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2025.1535246","article-title":"Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action","volume":"15","author":"Karunarathna","year":"2025","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.jgeb.2026.100714_bb0490","article-title":"Ganoderma lucidum: insight into antimicrobial and antioxidant properties with development of secondary metabolites","volume":"10","author":"Ahmad","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.jgeb.2026.100714_bb0495","first-page":"1","article-title":"In-vitro antibacterial activity of some Ganoderma species: a review","author":"Arora","year":"2023","journal-title":"Qeios"}],"container-title":["Journal of Genetic Engineering and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1687157X26000582?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1687157X26000582?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:53:02Z","timestamp":1789559582000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1687157X26000582"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":99,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1687157X26000582"],"URL":"https:\/\/doi.org\/10.1016\/j.jgeb.2026.100714","relation":{},"ISSN":["1687-157X"],"issn-type":[{"value":"1687-157X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence and antibiotic resistance pattern of Staphylococcus spp. isolated from acne, and disrupting their antimicrobial resistance: unveiling the potential of Ganoderma lucidum extract","name":"articletitle","label":"Article Title"},{"value":"Journal of Genetic Engineering and Biotechnology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgeb.2026.100714","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of Academy of Scientific Research and Technology.","name":"copyright","label":"Copyright"}],"article-number":"100714"}}