{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:55:06Z","timestamp":1790661306420,"version":"4.1.0"},"reference-count":77,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetics and Genomics"],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1016\/j.jgg.2011.05.005","type":"journal-article","created":{"date-parts":[[2011,6,20]],"date-time":"2011-06-20T06:04:04Z","timestamp":1308549844000},"page":"271-278","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"title":["Recent progress in the genetics of generalized vitiligo"],"prefix":"10.1016","volume":"38","author":[{"given":"Richard A.","family":"Spritz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgg.2011.05.005_bib1","first-page":"244","article-title":"On the constitutional and local effects of disease of the suprarenal capsules","volume":"vol. 2","author":"Addison","year":"1855"},{"key":"10.1016\/j.jgg.2011.05.005_bib2","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1744-313X.1995.tb00232.x","article-title":"Study of HLA class I\/IL and T\u00a0lymphocyte subsets in Kuwaiti vitiligo patients","volume":"22","author":"al-Fouzan","year":"1995","journal-title":"Eur. J. Immunogenet."},{"key":"10.1016\/j.jgg.2011.05.005_bib3","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s00403-010-1064-1","article-title":"Genetic association of NALP1 with generalized vitiligo in Jordanian Arabs","volume":"302","author":"Alkhateeb","year":"2010","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib4","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1093\/hmg\/11.6.661","article-title":"Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2","volume":"11","author":"Alkhateeb","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib5","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1034\/j.1600-0749.2003.00032.x","article-title":"Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families","volume":"16","author":"Alkhateeb","year":"2003","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib7","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.0022-202X.2005.23822.x","article-title":"Candidate functional promoter variant in the FOXD3 melanoblast developmental regulator gene in autosomal dominant vitiligo","volume":"125","author":"Alkhateeb","year":"2005","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib8","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1365-2133.1993.tb03167.x","article-title":"Difference in clinical features and HLA antigens between familial and non-familial vitiligo of generalized type","volume":"129","author":"Ando","year":"1993","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib9","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1007\/s00439-002-0687-5","article-title":"Vitiligo: complex segregation and linkage disequilibrium analyses with respect to microsatellite loci spanning the HLA","volume":"110","author":"Arcos-Burgos","year":"2002","journal-title":"Hum. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib10","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/path.1711700209","article-title":"An immunohistological study of cutaneous lymphocytes in vitiligo","volume":"170","author":"Badri","year":"1993","journal-title":"J. Pathol."},{"key":"10.1016\/j.jgg.2011.05.005_bib12","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1001\/archderm.144.3.310","article-title":"A Romanian population isolate with high frequency of vitiligo and associated autoimmune diseases","volume":"144","author":"Birlea","year":"2008","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib13","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1755-148X.2009.00543.x","article-title":"CTLA4 and generalized vitiligo: two genetic association studies and a meta-analysis of published data","volume":"22","author":"Birlea","year":"2009","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib14","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1038\/jid.2009.347","article-title":"Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8","volume":"130","author":"Birlea","year":"2010","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib15","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/jid.2010.337","article-title":"Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP","volume":"131","author":"Birlea","year":"2011","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib16","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1038\/ng.411","article-title":"Genome-wide association study identifies three loci associated with melanoma risk","volume":"41","author":"Bishop","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1600-0749.2004.00196.x","article-title":"CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases","volume":"18","author":"Blomhoff","year":"2005","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib18","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1600-0625.2008.00826.x","article-title":"Frontiers and controversies in the pathobiology of vitiligo: separating the wheat from the chaff","volume":"18","author":"Boissy","year":"2009","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1462399405009981","article-title":"HLA, CTLA-4, and PTPN22: the shared genetic master-key to autoimmunity?","volume":"7","author":"Brand","year":"2005","journal-title":"Expert Rev. Mol. Med."},{"key":"10.1016\/j.jgg.2011.05.005_bib20","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/sj.gene.6364243","article-title":"A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo","volume":"6","author":"Cant\u00f3n","year":"2005","journal-title":"Genes Immun."},{"key":"10.1016\/j.jgg.2011.05.005_bib21","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1038\/sj.gene.6364016","article-title":"Genes of the LMP\/TAP cluster are associated with the human autoimmune disease vitiligo","volume":"4","author":"Casp","year":"2003","journal-title":"Genes Immun."},{"key":"10.1016\/j.jgg.2011.05.005_bib22","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1086\/430279","article-title":"A novel linkage to generalized vitiligo on 4q13-q21 identified in a genomewide linkage analysis of Chinese families","volume":"76","author":"Chen","year":"2005","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib23","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/MCG.0b013e3181e8ae93","article-title":"Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases","volume":"45","author":"De Iudicibus","year":"2011","journal-title":"J. Clin. Gastroenterol."},{"key":"10.1016\/j.jgg.2011.05.005_bib24","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1136\/ard.2010.131243","article-title":"NLRP1 influences the systemic sclerosis phenotype: a new clue for the contribution of innate immunity in systemic sclerosis-related fibrosing alveolitis pathogenesis","volume":"70","author":"Dieud\u00e9","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.jgg.2011.05.005_bib77","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1086\/375451","article-title":"A genomewide screen for generalized vitiligo: confirmation of AIS1 on chromosome 1p31 and evidence for additional susceptibility loci","volume":"72","author":"Fain","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib25","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1600-0749.2005.00279.x","article-title":"HLA class II haplotype DRB1\u221704-DQB1\u22170301 contributes to risk of familial generalized vitiligo and early disease onset","volume":"19","author":"Fain","year":"2006","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib26","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1111\/j.1399-0004.1991.tb02984.x","article-title":"Age of onset in vitiligo: relationship with HLA supratypes","volume":"39","author":"Finco","year":"1991","journal-title":"Clin. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib27","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0190-9622(83)80279-5","article-title":"Association of HLA-DR4 with vitiligo","volume":"8","author":"Foley","year":"1983","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib28","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1038\/ng1333","article-title":"Assessing the impact of population stratification on genetic association studies","volume":"36","author":"Freedman","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib29","first-page":"277","article-title":"Mononuclear cell subpopulations and infiltrating lymphocytes in erythema dyschromicum perstans and vitiligo","volume":"2","author":"Gross","year":"1987","journal-title":"Histol. Histopathol."},{"key":"10.1016\/j.jgg.2011.05.005_bib30","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1038\/ng.161","article-title":"ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma","volume":"40","author":"Gudbjartsson","year":"2008","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib31","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1001\/archderm.1978.01640220095041","article-title":"Autoimmunity and vitiligo","volume":"114","author":"Harsoulis","year":"1978","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib32","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/00125817-200203000-00002","article-title":"A comprehensive review of genetic association studies","volume":"4","author":"Hirschhorn","year":"2002","journal-title":"Genet. Med."},{"key":"10.1016\/j.jgg.2011.05.005_bib33","first-page":"10","article-title":"NALP1 and vitiligo-associated multiple autoimmune disease","volume":"365","author":"Jin","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jgg.2011.05.005_bib34","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1038\/sj.jid.5700953","article-title":"Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population","volume":"127","author":"Jin","year":"2007","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib35","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1056\/NEJMoa0908547","article-title":"Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo","volume":"362","author":"Jin","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jgg.2011.05.005_bib36","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1038\/ng.602","article-title":"Common variants in FOXP1 are associated with generalized vitiligo","volume":"42","author":"Jin","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib37","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1038\/jid.2011.12","article-title":"Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset","volume":"131","author":"Jin","year":"2011","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib38","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s00439-004-1145-3","article-title":"Chromosome 17p12-q11 harbors susceptibility loci for systemic lupus erythematosus","volume":"115","author":"Johansson","year":"2004","journal-title":"Hum. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib39","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.cell.2008.07.021","article-title":"XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease","volume":"134","author":"Kaser","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.jgg.2011.05.005_bib40","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.autrev.2006.09.010","article-title":"Autoantibody responses to melanocytes in the depigmenting skin disease vitiligo","volume":"6","author":"Kemp","year":"2007","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.jgg.2011.05.005_bib41","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jdermsci.2006.08.001","article-title":"MYG1, novel melanocyte related gene, has elevated expression in vitiligo","volume":"44","author":"Kingo","year":"2006","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.jgg.2011.05.005_bib43","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1600-0749.2005.00242.x","article-title":"Early disease onset and increased risk of other autoimmune diseases in familial generalized vitiligo","volume":"18","author":"Laberge","year":"2005","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib42","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1038\/sj.jid.5701233","article-title":"PTPN22 is genetically associated with risk of generalized vitiligo, but CTLA4 is not","volume":"128","author":"Laberge","year":"2008","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib44","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.1755-148X.2008.00443.x","article-title":"The PTPN22-1858C>T (R620W) functional polymorphism is associated with generalized vitiligo in the Romanian population","volume":"21","author":"Laberge","year":"2008","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib45","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jdermsci.2007.10.002","article-title":"Association of PTPN22 1858C\/T polymorphism with vitiligo susceptibility in Gujarat population","volume":"49","author":"Laddha","year":"2008","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.jgg.2011.05.005_bib46","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/j.1600-065X.2008.00730.x","article-title":"Inflammasomes: guardians of cytosolic sanctity","volume":"227","author":"Lamkanfi","year":"2009","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.jgg.2011.05.005_bib47","first-page":"1219","article-title":"Presence of T cells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance","volume":"148","author":"Le Poole","year":"1996","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.jgg.2011.05.005_bib48","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1034\/j.1600-0749.2001.140608.x","article-title":"\u2018VIT1\u2019, a novel gene associated with vitiligo","volume":"14","author":"Le Poole","year":"2001","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib49","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.1038\/sj.jid.5700904","article-title":"Evidence for two susceptibility loci on chromosomes 22q12 and 6p21-p22 in Chinese generalized vitiligo families","volume":"127","author":"Liang","year":"2007","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib50","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1468-3083.2006.01899.x","article-title":"Association of vitiligo with HLA-A2: a meta-analysis","volume":"21","author":"Liu","year":"2007","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.jgg.2011.05.005_bib51","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/gene.2008.85","article-title":"A coding polymorphism in NALP1 confers risk for autoimmune Addison\u2019s disease and type 1 diabetes","volume":"10","author":"Magitta","year":"2009","journal-title":"Genes Immun."},{"key":"10.1016\/j.jgg.2011.05.005_bib52","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1086\/324470","article-title":"Evidence for a susceptibility gene, SLEV1, on chromosome 17p13 in families with vitiligo-related systemic lupus erythematosus","volume":"69","author":"Nath","year":"2001","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib53","series-title":"Symposium on Autoimmune Aspects of Endocrine Disorders","first-page":"357","article-title":"Polyglandular autoimmune diseases","author":"Neufeld","year":"1980"},{"key":"10.1016\/j.jgg.2011.05.005_bib54","series-title":"The Pigmentary System","first-page":"551","article-title":"Vitiligo vulgaris","author":"Nordlund","year":"2006"},{"key":"10.1016\/j.jgg.2011.05.005_bib55","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1084\/jem.188.6.1203","article-title":"High frequency of skin-homing melanocyte specific cytotoxic T lymphocytes in autoimmune vitiligo","volume":"188","author":"Ogg","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jgg.2011.05.005_bib56","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1034\/j.1600-0749.2003.00023.x","article-title":"Evidence for an autoimmune pathogenesis of vitiligo","volume":"16","author":"Ongenae","year":"2003","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib57","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000247426","article-title":"Vitiligo is associated with a significant increase in HLA-A30, Cw6 and Dqw3 and a decrease in C4AQ0 in northern Italian patients","volume":"185","author":"Orecchia","year":"1992","journal-title":"Dermatology"},{"key":"10.1016\/j.jgg.2011.05.005_bib58","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1684\/ejd.2008.0578","article-title":"Association between IL4 (-590), ACE (I)\/(D), CCR5 (\u039432), CTLA4 (+49) and IL1-RN (VNTR in intron 2) gene polymorphisms and vitiligo","volume":"19","author":"Pehlivan","year":"2009","journal-title":"Eur. J. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib79","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1471-2350-11-56","article-title":"Promoter polymorphism -119C\/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1","volume":"11","author":"Philips","year":"2010","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib59","series-title":"Vitiligo","year":"2010"},{"key":"10.1016\/j.jgg.2011.05.005_bib60","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/ajg.2010.474","article-title":"The missense variation Q705K in CIAS1\/NALP3\/NLRP3 gene and an NLRP1 haplotype are associated with celiac disease","volume":"106","author":"Pontillo","year":"2011","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.jgg.2011.05.005_bib61","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/ng.603","article-title":"Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC","volume":"42","author":"Quan","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib62","doi-asserted-by":"crossref","first-page":"e1000523","DOI":"10.1371\/journal.pgen.1000523","article-title":"Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo","volume":"5","author":"Ren","year":"2009","journal-title":"PLoS Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib63","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1159\/000247240","article-title":"Histocompatibility antigens in vitiligo: Hamburg study on 102 patients from northern Germany","volume":"187","author":"Schallreuter","year":"1993","journal-title":"Dermatology"},{"key":"10.1016\/j.jgg.2011.05.005_bib64","first-page":"212","article-title":"Eine biglanduiare Erkrankung (Nebennieren und Schilddruse) bei Morbus Addisonii","volume":"21","author":"Schmidt","year":"1926","journal-title":"Verh. Dtsch. Ges. Pathol."},{"key":"10.1016\/j.jgg.2011.05.005_bib65","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1084\/jem.183.2.527","article-title":"An HLA-A2-restricted tyrosinase antigen on melanoma cells results from posttranslational modification and suggests a novel pathway for processing of membrane proteins","volume":"183","author":"Skipper","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.jgg.2011.05.005_bib66","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1159\/000131501","article-title":"The genetics of generalized vitiligo","volume":"10","author":"Spritz","year":"2008","journal-title":"Curr. Dir. Autoimmun."},{"key":"10.1016\/j.jgg.2011.05.005_bib78","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/gm199","article-title":"The genetics of generalized vitiligo: autoimmune pathways and an inverse relationship with malignant melanoma","volume":"2","author":"Spritz","year":"2010","journal-title":"Genome Med."},{"key":"10.1016\/j.jgg.2011.05.005_bib67","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1086\/381134","article-title":"Novel vitiligo susceptibility loci on chromosomes 7 (AIS2) and 8 (AIS3), confirmation of SLEV1 on chromosome 17, and their roles in an autoimmune diathesis","volume":"74","author":"Spritz","year":"2004","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jgg.2011.05.005_bib68","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/j.1755-148X.2007.00429.x","article-title":"Transcriptional profiling of melanocytes from patients with vitiligo vulgaris","volume":"21","author":"Str\u00f6mberg","year":"2008","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib69","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1111\/j.1365-4632.2006.02907.x","article-title":"Genetic epidemiology of vitiligo: a study of 815 probands and their families from south China","volume":"45","author":"Sun","year":"2006","journal-title":"Int. J. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib70","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1056\/NEJMcp0804388","article-title":"Vitiligo","volume":"360","author":"Ta\u00efeb","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.jgg.2011.05.005_bib71","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1600-0749.2004.00141.x","article-title":"Association of HLA class I antigens and HLA class II alleles with vitiligo in a Turkish population","volume":"17","author":"Tastan","year":"2004","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.jgg.2011.05.005_bib72","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1042\/bj3550259","article-title":"The molecular basis of oculocutaneous albinism type 1 (OCA1): sorting failure and degradation of mutant tyrosinases results in a lack of pigmentation","volume":"355","author":"Toyofuku","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.jgg.2011.05.005_bib73","first-page":"103","article-title":"A polymorphism of the human tyrosinase gene that is associated with temperature-sensitive enzymatic activity","volume":"1","author":"Tripathi","year":"1991","journal-title":"Gene Expr."},{"key":"10.1016\/j.jgg.2011.05.005_bib74","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/j.1468-3083.2006.01686.x","article-title":"MHC haplotypic association in Chinese Han patients with vitiligo","volume":"20","author":"Xia","year":"2006","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.jgg.2011.05.005_bib75","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1046\/j.1365-2133.2001.04288.x","article-title":"Linkage and association of HLA class II genes with vitiligo in a Dutch population","volume":"145","author":"Zamani","year":"2001","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.jgg.2011.05.005_bib76","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.humimm.2010.02.004","article-title":"A coding variant in NLRP1 is associated with autoimmune Addison\u2019s disease","volume":"71","author":"Zurawek","year":"2010","journal-title":"Hum. Immunol."}],"container-title":["Journal of Genetics and Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1673852711000907?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1673852711000907?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T11:22:45Z","timestamp":1761650565000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1673852711000907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":77,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["S1673852711000907"],"URL":"https:\/\/doi.org\/10.1016\/j.jgg.2011.05.005","relation":{},"ISSN":["1673-8527"],"issn-type":[{"value":"1673-8527","type":"print"}],"subject":[],"published":{"date-parts":[[2011,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recent progress in the genetics of generalized vitiligo","name":"articletitle","label":"Article Title"},{"value":"Journal of Genetics and Genomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgg.2011.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}