{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:29:44Z","timestamp":1790879384107,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["2017SHZDZX01"],"award-info":[{"award-number":["2017SHZDZX01"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31900408"],"award-info":[{"award-number":["31900408"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32271186"],"award-info":[{"award-number":["32271186"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32325013"],"award-info":[{"award-number":["32325013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018684","name":"National Health Commission of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018684","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDB38020400"],"award-info":[{"award-number":["XDB38020400"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["YSBR-077"],"award-info":[{"award-number":["YSBR-077"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003347","name":"Fudan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","award":["B13016"],"award-info":[{"award-number":["B13016"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003345","name":"Chinese Academy of Meteorological Sciences","doi-asserted-by":"publisher","award":["2019-I2M-5-066"],"award-info":[{"award-number":["2019-I2M-5-066"]}],"id":[{"id":"10.13039\/501100003345","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Genetics and Genomics"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.jgg.2024.07.005","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T17:53:25Z","timestamp":1720720405000},"page":"513-524","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["A multi-ancestry GWAS meta-analysis of facial features and its application in predicting archaic human features"],"prefix":"10.1016","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1602-1669","authenticated-orcid":false,"given":"Siyuan","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jieyi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiarui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijie","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2994-3083","authenticated-orcid":false,"given":"Sibte Syed","family":"Hadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingze","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyu","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiucun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqin","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinran","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"Ruiz-Linares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongyong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6961-7867","authenticated-orcid":false,"given":"Sijia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jgg.2024.07.005_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms11616","article-title":"A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation","volume":"7","author":"Adhikari","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jgg.2024.07.005_bib2","doi-asserted-by":"crossref","first-page":"7500","DOI":"10.1038\/ncomms8500","article-title":"A\u00a0genome-wide association study identifies multiple loci for variation in human ear morphology","volume":"6","author":"Adhikari","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jgg.2024.07.005_bib3","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/nature15393","article-title":"A\u00a0global reference for human genetic variation","volume":"526","author":"Altshuler","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.jgg.2024.07.005_bib4","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ajhg.2016.05.001","article-title":"Transethnic genetic-correlation estimates from summary statistics","volume":"99","author":"Brown","year":"2016","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib5","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/ng.3211","article-title":"LD score regression distinguishes confounding from polygenicity in genome-wide association studies","volume":"47","author":"Bulik-Sullivan","year":"2015","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib6","doi-asserted-by":"crossref","first-page":"D801","DOI":"10.1093\/nar\/gky1056","article-title":"Mouse Genome Database (MGD) 2019","volume":"47","author":"Bult","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jgg.2024.07.005_bib8","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/s41586-019-1139-x","article-title":"A\u00a0late Middle Pleistocene Denisovan mandible from the Tibetan Plateau","volume":"569","author":"Chen","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.jgg.2024.07.005_bib9","doi-asserted-by":"crossref","first-page":"21484","DOI":"10.1073\/pnas.1910606116","article-title":"Genetic contributions to variation in human stature in prehistoric Europe","volume":"116","author":"Cox","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jgg.2024.07.005_bib10","first-page":"100025","article-title":"The PAX1 locus at 20p11 is a potential genetic modifier for bilateral cleft lip","volume":"2","author":"Curtis","year":"2021","journal-title":"HGG Adv."},{"key":"10.1016\/j.jgg.2024.07.005_bib11","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1002\/gepi.22420","article-title":"FAT4 identified as a potential modifier of orofacial cleft laterality","volume":"45","author":"Curtis","year":"2021","journal-title":"Genet. Epidemiol."},{"key":"10.1016\/j.jgg.2024.07.005_bib12","doi-asserted-by":"crossref","first-page":"3934","DOI":"10.1038\/ncomms4934","article-title":"Integrating sequence and array data to create an improved 1000 genomes project haplotype reference panel","volume":"5","author":"Delaneau","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jgg.2024.07.005_bib13","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.jhevol.2012.08.002","article-title":"Middle Pleistocene human facial morphology in an evolutionary and developmental context","volume":"63","author":"Freidline","year":"2012","journal-title":"J.\u00a0Hum. Evol."},{"key":"10.1016\/j.jgg.2024.07.005_bib14","doi-asserted-by":"crossref","first-page":"D1333","DOI":"10.1093\/nar\/gkad1005","article-title":"The human phenotype ontology in 2024: phenotypes around the world","volume":"52","author":"Gargano","year":"2024","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.jgg.2024.07.005_bib15","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.cell.2019.08.035","article-title":"Reconstructing Denisovan anatomy using DNA methylation maps","volume":"179","author":"Gokhman","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.jgg.2024.07.005_bib16","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jhevol.2014.08.001","article-title":"Variation and signatures of selection on the human face","volume":"75","author":"Guo","year":"2014","journal-title":"J.\u00a0Hum. Evol."},{"key":"10.1016\/j.jgg.2024.07.005_bib17","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1038\/s41467-018-04191-y","article-title":"Global genetic differentiation of complex traits shaped by natural selection in humans","volume":"9","author":"Guo","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jgg.2024.07.005_bib18","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/nature26151","article-title":"Reconstructing the genetic history of late Neanderthals","volume":"555","author":"Hajdinjak","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.jgg.2024.07.005_bib19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2105-14-7","article-title":"GSVA: gene set variation analysis for microarray and RNA-seq data","volume":"14","author":"H\u00e4nzelmann","year":"2013","journal-title":"BMC Bioinf"},{"key":"10.1016\/j.jgg.2024.07.005_bib20","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.jhevol.2010.06.005","article-title":"Evolution of middle-late Pleistocene human cranio-facial form: a 3-D approach","volume":"59","author":"Harvati","year":"2010","journal-title":"J. Hum. Evol."},{"key":"10.1016\/j.jgg.2024.07.005_bib21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/(SICI)1096-8644(199710)104:2<245::AID-AJPA10>3.0.CO;2-#","article-title":"Postcranial evidence of cold adaptation in European Neandertals","volume":"104","author":"Holliday","year":"1997","journal-title":"Am. J. Phys. Anthropol."},{"key":"10.1016\/j.jgg.2024.07.005_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000529","article-title":"A\u00a0flexible and accurate genotype imputation method for the next generation of genome-wide association studies","volume":"5","author":"Howie","year":"2009","journal-title":"PLoS Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib23","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/nature13408","article-title":"Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA","volume":"512","author":"Huerta-S\u00e1nchez","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jgg.2024.07.005_bib24","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2009227118","article-title":"The evolution of skin pigmentation-associated variation in West Eurasia","volume":"118","author":"Ju","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jgg.2024.07.005_bib25","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1126\/science.309.5731.75","article-title":"What don't we know?","volume":"309","author":"Kennedy","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.jgg.2024.07.005_bib26","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ajhg.2018.11.008","article-title":"Leveraging polygenic functional enrichment to improve GWAS power","volume":"104","author":"Kichaev","year":"2019","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib27","article-title":"Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture","volume":"13","author":"Kim","year":"2018","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jgg.2024.07.005_bib28","article-title":"Genome-wide association study of facial morphology reveals novel associations with FREM1 and PARK2","volume":"12","author":"Lee","year":"2017","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jgg.2024.07.005_bib29","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/s42003-023-04838-7","article-title":"Automatic landmarking identifies new loci associated with face morphology and implicates Neanderthal introgression in human nasal shape","volume":"6","author":"Li","year":"2023","journal-title":"Commun. Biol."},{"key":"10.1016\/j.jgg.2024.07.005_bib31","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s43657-023-00105-1","article-title":"Quantitative assessment of ultraviolet-induced erythema and tanning responses in the Han Chinese population","volume":"4","author":"Ma","year":"2024","journal-title":"Phenomics"},{"key":"10.1016\/j.jgg.2024.07.005_bib32","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1038\/s41588-018-0241-6","article-title":"Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps","volume":"50","author":"Mahajan","year":"2018","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib33","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1038\/ng.2435","article-title":"Bayesian refinement of association signals for 14 loci in 3 common diseases","volume":"44","author":"Maller","year":"2012","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib35","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/s41597-024-03031-7","article-title":"The allen ancient DNA resource (AADR): a curated compendium of ancient human genomes","volume":"11","author":"Mallick","year":"2024","journal-title":"Sci. Data"},{"key":"10.1016\/j.jgg.2024.07.005_bib36","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1002\/ar.23040","article-title":"The nasal complex of Neanderthals: an entry portal to their place in human ancestry","volume":"297","author":"M\u00e1rquez","year":"2014","journal-title":"Anat. Rec."},{"key":"10.1016\/j.jgg.2024.07.005_bib37","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1126\/science.1224344","article-title":"A\u00a0high-coverage genome sequence from an archaic Denisovan individual","volume":"338","author":"Meyer","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.jgg.2024.07.005_bib38","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/s41588-018-0302-x","article-title":"An atlas of genetic influences on osteoporosis in humans and mice","volume":"51","author":"Morris","year":"2019","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib39","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jhevol.2015.11.002","article-title":"Virtual ancestor reconstruction: revealing the ancestor of modern humans and Neandertals","volume":"91","author":"Mounier","year":"2016","journal-title":"J.\u00a0Hum. Evol."},{"key":"10.1016\/j.jgg.2024.07.005_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.621482","article-title":"Genome-wide association study of non-syndromic orofacial clefts in a multiethnic sample of families and controls identifies novel regions","volume":"9","author":"Mukhopadhyay","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.jgg.2024.07.005_bib41","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/s41576-023-00643-4","article-title":"More than a decade of genetic research on the Denisovans","volume":"25","author":"Peyr\u00e9gne","year":"2024","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib42","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/ng.3570","article-title":"Detection and interpretation of shared genetic influences on 42 human traits","volume":"48","author":"Pickrell","year":"2016","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib43","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/35087573","article-title":"Neanderthal cranial ontogeny and its implications for late hominid diversity","volume":"412","author":"Ponce de Leon","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.jgg.2024.07.005_bib44","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.cell.2015.08.036","article-title":"Enhancer divergence and regulatory evolution in the human and chimp neural crest","volume":"163","author":"Prescott","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.jgg.2024.07.005_bib45","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1126\/science.aao1887","article-title":"A\u00a0high-coverage Neandertal genome from Vindija Cave in Croatia","volume":"358","author":"Pr\u00fcfer","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.jgg.2024.07.005_bib46","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/nature12886","article-title":"The complete\u00a0genome sequence of a Neanderthal from the Altai Mountains","volume":"505","author":"Pr\u00fcfer","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.jgg.2024.07.005_bib47","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.jgg.2022.02.020","article-title":"Genetic evidence for facial variation being a composite phenotype of cranial variation and facial soft tissue thickness","volume":"49","author":"Qian","year":"2022","journal-title":"J.\u00a0Genet. Genomics."},{"key":"10.1016\/j.jgg.2024.07.005_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s43657-023-00109-x","article-title":"De novo dissecting the three-dimensional facial morphology of 2379 Han Chinese individuals","volume":"4","author":"Qiao","year":"2024","journal-title":"Phenomics"},{"key":"10.1016\/j.jgg.2024.07.005_bib49","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.jhevol.2010.10.003","article-title":"The Neanderthal face is not cold adapted","volume":"60","author":"Rae","year":"2011","journal-title":"J.\u00a0Hum. Evol."},{"key":"10.1016\/j.jgg.2024.07.005_bib50","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/s41588-022-01054-7","article-title":"Improving polygenic prediction in ancestrally diverse populations","volume":"54","author":"Ruan","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib51","doi-asserted-by":"crossref","first-page":"4800","DOI":"10.1038\/ncomms5800","article-title":"Morphological and population genomic evidence that human faces have evolved to signal individual identity","volume":"5","author":"Sheehan","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jgg.2024.07.005_bib52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ajpa.1330910102","article-title":"Biomechanical analysis of masticatory system configuration in Neandertals and Inuits","volume":"91","author":"Spencer","year":"1993","journal-title":"Am. J. Phys. Anthropol."},{"key":"10.1016\/j.jgg.2024.07.005_bib53","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1002\/ajpa.23721","article-title":"Morphological trends in arcade shape and size in Middle Pleistocene Homo","volume":"168","author":"Stelzer","year":"2019","journal-title":"Am. J. Phys. Anthropol."},{"key":"10.1016\/j.jgg.2024.07.005_bib54","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1086\/519024","article-title":"A\u00a0Bayesian measure of the probability of false discovery in genetic epidemiology studies","volume":"81","author":"Wakefield","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib55","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/gepi.20359","article-title":"Bayes factors for genome-wide association studies: comparison with P-values","volume":"33","author":"Wakefield","year":"2009","journal-title":"Genet. Epidemiol."},{"key":"10.1016\/j.jgg.2024.07.005_bib56","doi-asserted-by":"crossref","first-page":"6085","DOI":"10.1038\/s41598-019-42533-y","article-title":"MeshMonk: open-source large-scale intensive 3D phenotyping","volume":"9","author":"White","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jgg.2024.07.005_bib57","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1093\/bioinformatics\/btq340","article-title":"METAL: fast and efficient meta-analysis of genomewide association scans","volume":"26","author":"Willer","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jgg.2024.07.005_bib58","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/ajpa.22895","article-title":"Postnatal craniofacial ontogeny in Neandertals and modern humans","volume":"159","author":"Williams","year":"2016","journal-title":"Am. J. Phys. Anthropol."},{"key":"10.1016\/j.jgg.2024.07.005_bib59","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/s41586-024-07612-9","article-title":"Middle and Late Pleistocene Denisovan subsistence at Baishiya Karst Cave","volume":"632","author":"Xia","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.jgg.2024.07.005_bib60","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.49898","article-title":"Novel genetic loci affecting facial shape variation in humans","volume":"8","author":"Xiong","year":"2019","journal-title":"Elife"},{"key":"10.1016\/j.jgg.2024.07.005_bib61","doi-asserted-by":"crossref","first-page":"7832","DOI":"10.1038\/s41467-022-35328-9","article-title":"Combining genome-wide association studies highlight novel loci involved in human facial variation","volume":"13","author":"Xiong","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jgg.2024.07.005_bib62","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1006616","article-title":"Investigating the case of human nose shape and climate adaptation","volume":"13","author":"Zaidi","year":"2017","journal-title":"PLoS Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib63","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/s41588-022-01038-7","article-title":"Genetic variants underlying differences in facial morphology in East Asian and European populations","volume":"54","author":"Zhang","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.jgg.2024.07.005_bib64","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1038\/s41467-019-09234-6","article-title":"Metascape provides a biologist-oriented resource for the analysis of systems-level datasets","volume":"10","author":"Zhou","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jgg.2024.07.005_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13742-015-0047-8","article-title":"Second-generation PLINK: rising to the challenge of larger and richer datasets","volume":"4","author":"Chang","year":"2015","journal-title":"Gigascience"},{"key":"10.1016\/j.jgg.2024.07.005_bib34","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/s41597-024-03031-7","article-title":"The allen ancient DNA resource (AADR) a curated compendium of ancient human genomes","volume":"11","author":"Mallick","year":"2024","journal-title":"Sci. Data"}],"container-title":["Journal of Genetics and Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1673852724001814?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1673852724001814?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T22:38:34Z","timestamp":1762555114000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1673852724001814"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":63,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S1673852724001814"],"URL":"https:\/\/doi.org\/10.1016\/j.jgg.2024.07.005","relation":{},"ISSN":["1673-8527"],"issn-type":[{"value":"1673-8527","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A multi-ancestry GWAS meta-analysis of facial features and its application in predicting archaic human features","name":"articletitle","label":"Article Title"},{"value":"Journal of Genetics and Genomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jgg.2024.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and Genetics Society of China. Published by Elsevier Limited and Science Press\u00e9","name":"copyright","label":"Copyright"}]}}