{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T15:47:12Z","timestamp":1794584832533,"version":"4.9.1"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-15-JOCE-0002-05"],"award-info":[{"award-number":["ANR-15-JOCE-0002-05"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001862","name":"Svenska Forskningsr\u00e5det Formas","doi-asserted-by":"publisher","award":["942-2015-1865"],"award-info":[{"award-number":["942-2015-1865"]}],"id":[{"id":"10.13039\/501100001862","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["PCIN-2015-187-C03-03"],"award-info":[{"award-number":["PCIN-2015-187-C03-03"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["CTM2016-77945-C3"],"award-info":[{"award-number":["CTM2016-77945-C3"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hazardous Materials"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.jhazmat.2018.07.101","type":"journal-article","created":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T12:55:31Z","timestamp":1533300931000},"page":"452-460","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":212,"special_numbering":"C","title":["Ingestion and contact with polyethylene microplastics does not cause acute toxicity on marine zooplankton"],"prefix":"10.1016","volume":"360","author":[{"given":"R.","family":"Beiras","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Bellas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Cachot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Cormier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Cousin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Engwall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Gambardella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Garaventa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Keiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Le Bihanic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"L\u00f3pez-Ib\u00e1\u00f1ez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Piazza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Rial","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Tato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Vidal-Li\u00f1\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhazmat.2018.07.101_bib0005","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1126\/science.1260352","article-title":"Plastic waste inputs from land into the ocean","volume":"347","author":"Jambeck","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0010","doi-asserted-by":"crossref","first-page":"4732","DOI":"10.1021\/es4053076","article-title":"Distribution of surface plastic debris in the eastern Pacific ocean from an 11-year data set","volume":"48","author":"Law","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0015","series-title":"Marine Anthropogenic Litter","first-page":"29","article-title":"Global distribution, composition and abundance of Marine litter","author":"Galgani","year":"2015"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0020","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1098\/rstb.2008.0205","article-title":"Accumulation and fragmentation of plastic debris in global environments","volume":"364","author":"Barnes","year":"2009","journal-title":"Philos. Trans. Biol. Sci."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0025","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.scitotenv.2017.10.101","article-title":"No increase in marine microplastic concentration over the last three decades\u2014a case study from the Baltic Sea","volume":"621","author":"Beer","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0030","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2307\/1542425","article-title":"Particle captures and the method of suspension feeding by echinoderm larvae","volume":"180","author":"Hart","year":"1991","journal-title":"Biol. Bull."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0035","doi-asserted-by":"crossref","first-page":"6646","DOI":"10.1021\/es400663f","article-title":"Microplastic ingestion by zooplankton","volume":"47","author":"Cole","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0040","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.envpol.2013.10.013","article-title":"Ingestion and transfer of microplastics in the planktonic food web","volume":"185","author":"Set\u00e4l\u00e4","year":"2014","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0045","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.marpolbul.2014.12.050","article-title":"Assessment of microplastic toxicity to embryonic development of the sea urchin Lytechinus variegatus (Echinodermata: Echinoidea)","volume":"92","author":"Nobre","year":"2015","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0050","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.marenvres.2017.06.016","article-title":"The adverse effects of virgin microplastics on the fertilization and larval development of sea urchins","volume":"130","author":"Mart\u00ednez-G\u00f3mez","year":"2017","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0055","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1021\/es504525u","article-title":"The impact of polystyrene microplastics on feeding, function and fecundity in the marine copepod Calanus helgolandicus","volume":"49","author":"Cole","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0060","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1021\/es404295e","article-title":"Ingestion of microplastic has limited impact on a marine larva","volume":"48","author":"Kaposi","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0065","doi-asserted-by":"crossref","first-page":"14625","DOI":"10.1021\/acs.est.5b04099","article-title":"Ingestion of nanoplastics and microplastics by Pacific oyster larvae","volume":"49","author":"Cole","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0070","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.envpol.2017.08.088","article-title":"Aging of microplastics promotes their ingestion by marine zooplankton","volume":"231","author":"Vroom","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0075","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.ecoenv.2017.07.036","article-title":"Effects of polystyrene microbeads in marine planktonic crustaceans","volume":"145","author":"Gambardella","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0080","series-title":"An Analysis of European Plastics Production, Demand and Waste Data","article-title":"Plastics\u2014the facts 2016","author":"PlasticsEurope","year":"2016"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0085","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1021\/es2031505","article-title":"Microplastics in the marine environment: a review of the methods used for identification and quantification","volume":"46","author":"Hidalgo-Ruz","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0090","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1039\/b806198j","article-title":"Inputs of chemicals from recreational activities into the Norwegian coastal zone","volume":"10","author":"Langford","year":"2008","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0095","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.chemosphere.2015.02.054","article-title":"Occurrence of eight UV filters in beaches of Gran Canaria (Canary Islands). An approach to environmental risk assessment","volume":"131","author":"S\u00e1nchez Rodr\u00edguez","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0100","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.envpol.2017.09.031","article-title":"Ecotoxicological evaluation of the risk posed by bisphenol A, triclosan, and 4-nonylphenol in coastal waters using early life stages of marine organisms (Isochrysis galbana, Mytilus galloprovincialis, Paracentrotus lividus, and Acartia clausi)","volume":"232","author":"Tato","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0105","series-title":"Advances in Marine Biology","doi-asserted-by":"crossref","DOI":"10.1016\/S0065-2881(08)60428-9","article-title":"The assessment of Marine pollution - bioassays with bivalve embryos and larvae","author":"His","year":"1999"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0110","first-page":"539","article-title":"Bioassay data for marine pollution using echinoderms","volume":"9","author":"Kobayashi","year":"1995","journal-title":"Encycl. Environ. Control Technol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0115","series-title":"Sources, Fate and Effects of Pollutants in Coastal Ecosystems","article-title":"Marine pollution","author":"Beiras","year":"2018"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0120","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.marpolbul.2014.08.023","article-title":"Microplastic pollution in the Northeast Atlantic Ocean: validated and opportunistic sampling","volume":"88","author":"Lusher","year":"2014","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0125","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.marenvres.2014.01.001","article-title":"Evidence of microplastics in samples of zooplankton from Portuguese coastal waters","volume":"95","author":"Frias","year":"2014","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0130","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.taap.2012.06.008","article-title":"Effects of the UV filter benzophenone-3 (oxybenzone) at low concentrations in zebrafish (Danio rerio)","volume":"263","author":"Bl\u00fcthgen","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0135","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/j.marenvres.2009.10.010","article-title":"A tentative environmental risk assessment of the UV-filters 3-(4-methylbenzylidene-camphor), 2-ethyl-hexyl-4-trimethoxycinnamate, benzophenone-3, benzophenone-4 and 3-benzylidene camphor","volume":"69","author":"Fent","year":"2010","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0140","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.chemosphere.2013.10.053","article-title":"Ecotoxicological evaluation of four UV filters using marine organisms from different trophic levels Isochrysis galbana, Mytilus galloprovincialis, Paracentrotus lividus, and Siriella armata","volume":"104","author":"Paredes","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0145","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1289\/ehp.01109239","article-title":"In vitro and in vivo estrogenicity of UV screens","volume":"109","author":"Schlumpf","year":"2001","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0150","article-title":"American Society for the Testing of Materials International Standards","volume":"11.05","author":"ASTM","year":"2004"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0155","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1007\/s10646-010-0461-8","article-title":"Swimming speed alteration of Artemia sp. and Brachionus plicatilis as a sub-lethal behavioural end-point for ecotoxicological surveys","volume":"19","author":"Garaventa","year":"2010","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0160","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jprot.2015.09.005","article-title":"Secreted protein eco-corona mediates uptake and impacts of polystyrene nanoparticles on Daphnia magna","volume":"137","author":"Nasser","year":"2016","journal-title":"J. Proteomics"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0165","author":"UNICHIM","year":"2014"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0170","series-title":"Water Quality: Determination of Acute Lethal Toxicity to Marine Copepods (Copepoda, Crustacea), Gen\u00e8ve, Switzerland","author":"ISO14669","year":"1999"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0175","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ecoenv.2015.10.013","article-title":"Tigriopus fulvus: the interlaboratory comparison of the acute toxicity test","volume":"124","author":"Faraponova","year":"2016","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0180","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.aquaculture.2008.03.002","article-title":"Inhibition of embryo development of the Mytilus galloprovincialis marine mussel by organic pollutants; assessment of risk for its extensive culture in the Galician Rias","volume":"277","author":"Beiras","year":"2008","journal-title":"Aquaculture"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0185","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0043-1354(96)00244-8","article-title":"A simplification the bivalve embryogenesis and larval development bioassay method for water quality assessment","volume":"31","author":"His","year":"1997","journal-title":"Water Res."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0190","series-title":"ICES Techniques in Marine Environmental Sciences","article-title":"Biological effects of contaminants: Paracentrotus lividus sea urchin embryo test with marine sediment elutriates","author":"Beiras","year":"2012"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0195","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ecoenv.2010.01.018","article-title":"Methodological basis for the optimization of a marine sea-urchin embryo test (SET) for the ecological assessment of coastal water quality","volume":"73","author":"Saco-\u00c1lvarez","year":"2010","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0200","first-page":"2055","article-title":"Dechorionation of medaka embryos and cell transplantation for the generation of chimeras","author":"Porazinski","year":"2010","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0205","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1007\/s00244-005-0319-x","article-title":"Modified Japanese medaka embryo-larval bioassay for rapid determination of developmental abnormalities","volume":"51","author":"Farwell","year":"2006","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0210","series-title":"OECD Organization for Economic Cooperation and Development Guidelines for the Testing of Chemicals. Section 2: Effects on Biotic Systems Test no. 236: Fish Embryo Acute Toxicity (FET) Test","year":"2013"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0215","series-title":"Directive 2010\/63\/EU of the European Parliament and of the Council of 22 September 2010 on the Protection of Animals Used for Scientific Purposes","year":"2010"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0220","series-title":"Statistical Method In Biological Assay","author":"Finney","year":"1978"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0225","series-title":"REPORT SNO. 6754-2014. Microplastics in Marine Environments: Occurrence, Distribution and Effects","author":"Nerland","year":"2014"},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0230","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.envpol.2013.10.007","article-title":"Enhanced desorption of persistent organic pollutants from microplastics under simulated physiological conditions","volume":"185","author":"Bakir","year":"2014","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0235","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.envpol.2014.12.021","article-title":"Pollutants bioavailability and toxicological risk from microplastics to marine mussels","volume":"198","author":"Avio","year":"2015","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0240","doi-asserted-by":"crossref","first-page":"3315","DOI":"10.1021\/acs.est.5b06069","article-title":"Microplastic as a vector for chemicals in the aquatic environment: critical review and model-supported reinterpretation of empirical studies","volume":"50","author":"Koelmans","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0245","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1002\/etc.3461","article-title":"Microplastics as vectors for bioaccumulation of hydrophobic organic chemicals in the marine environment: a state-of-the-science review","volume":"35","author":"Ziccardi","year":"2016","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0250","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.envpol.2016.09.033","article-title":"Differential bioavailability of polychlorinated biphenyls associated with environmental particles: microplastic in comparison to wood, coal and biochar","volume":"220","author":"Beckingham","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.jhazmat.2018.07.101_bib0255","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1002\/ieam.1914","article-title":"Microplastics are not important for the cycling and bioaccumulation of organic pollutants in the oceans\u2014but should microplastics be considered POPs themselves?","volume":"13","author":"Lohmann","year":"2017","journal-title":"Integr. Environ. Assess. Manage."}],"container-title":["Journal of Hazardous Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304389418306617?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304389418306617?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T17:01:12Z","timestamp":1759597272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304389418306617"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":51,"alternative-id":["S0304389418306617"],"URL":"https:\/\/doi.org\/10.1016\/j.jhazmat.2018.07.101","relation":{},"ISSN":["0304-3894"],"issn-type":[{"value":"0304-3894","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ingestion and contact with polyethylene microplastics does not cause acute toxicity on marine zooplankton","name":"articletitle","label":"Article Title"},{"value":"Journal of Hazardous Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhazmat.2018.07.101","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}