{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T19:15:54Z","timestamp":1793301354262,"version":"4.5.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970764"],"award-info":[{"award-number":["81970764"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371034"],"award-info":[{"award-number":["82371034"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171028"],"award-info":[{"award-number":["82171028"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2022-1-1081"],"award-info":[{"award-number":["2022-1-1081"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hazardous Materials"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.jhazmat.2025.137635","type":"journal-article","created":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T11:35:28Z","timestamp":1739878528000},"page":"137635","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Identification of microplastics in human tear fluid and meibum: Implications for dry eye disease pathogenesis"],"prefix":"10.1016","volume":"489","author":[{"given":"Jingyi","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanmin","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xixuan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yating","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2649-8241","authenticated-orcid":false,"given":"Ying","family":"Jie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhazmat.2025.137635_bib1","doi-asserted-by":"crossref","first-page":"eadl2746","DOI":"10.1126\/science.adl2746","article-title":"Twenty years of microplastics pollution research-what have we learned?","author":"Thompson","year":"2024","journal-title":"Sci (N Y, N Y )"},{"issue":"7","key":"10.1016\/j.jhazmat.2025.137635_bib2","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1700782","article-title":"Production, use, and fate of all plastics ever made","volume":"3","author":"Geyer","year":"2017","journal-title":"Sci Adv"},{"key":"10.1016\/j.jhazmat.2025.137635_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.123415","article-title":"Environmental fate, toxicity and risk management strategies of nanoplastics in the environment: Current status and future perspectives","volume":"401","author":"Wang","year":"2021","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135329","article-title":"Microplastics monitoring in freshwater systems: A review of global efforts, knowledge gaps, and research priorities","volume":"477","author":"Zhao","year":"2024","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.178298","article-title":"Microplastics in soils: A comprehensive review","volume":"960","author":"Kang","year":"2025","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jhazmat.2025.137635_bib6","article-title":"The threat of micro\/nanoplastic to aquatic plants: current knowledge, gaps, and future perspectives","volume":"265","author":"Osman","year":"2023","journal-title":"Aquat Toxicol (Amst, Neth)"},{"key":"10.1016\/j.jhazmat.2025.137635_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.134125","article-title":"Degradation of excavated polyethylene and polypropylene waste from landfill","volume":"698","author":"Canopoli","year":"2020","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jhazmat.2025.137635_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123288","article-title":"Characteristics and risks of microplastic contamination in aquaculture ponds near the Yangtze Estuary, China","volume":"343","author":"Huang","year":"2024","journal-title":"Environ Pollut (Barking, Essex: 1987)"},{"key":"10.1016\/j.jhazmat.2025.137635_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.167431","article-title":"Distribution of microplastic contamination in the major tributaries of the Yellow River on the Loess Plateau","volume":"905","author":"Zhao","year":"2023","journal-title":"Sci Total Environ"},{"issue":"1","key":"10.1016\/j.jhazmat.2025.137635_bib10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12989-024-00592-8","article-title":"Investigation of pulmonary inflammatory responses following intratracheal instillation of and inhalation exposure to polypropylene microplastics","volume":"21","author":"Tomonaga","year":"2024","journal-title":"Part Fibre Toxicol"},{"key":"10.1016\/j.jhazmat.2025.137635_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135532","article-title":"Seasonal microplastic ingestion by carnivorous chaetognaths in Jiaozhou Bay, China: Field evidence revealing microplastic trophic transfer","volume":"478","author":"Meng","year":"2024","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.133359","article-title":"Microplastic-induced inhibition of cell adhesion and toxicity evaluation using human dermal fibroblast-derived spheroids","volume":"465","author":"Eom","year":"2024","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135527","article-title":"Placental and fetal enrichment of microplastics from disposable paper cups: implications for metabolic and reproductive health during pregnancy","volume":"478","author":"Chen","year":"2024","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.129361","article-title":"Absorption, distribution, metabolism, excretion and toxicity of microplastics in the human body and health implications","volume":"437","author":"Wu","year":"2022","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121829","article-title":"Microplastics as vectors of chemical contaminants and biological agents in freshwater ecosystems: Current knowledge status and future perspectives","volume":"330","author":"Tumwesigye","year":"2023","journal-title":"Environ Pollut (Barking, Essex: 1987)"},{"key":"10.1016\/j.jhazmat.2025.137635_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.135054","article-title":"Percutaneous coronary intervention leads to microplastics entering the blood: Interventional devices are a major source","volume":"476","author":"Liu","year":"2024","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2024.153799","article-title":"The effects of micro- and nanoplastics on the central nervous system: A new threat to humanity?","volume":"504","author":"Zheng","year":"2024","journal-title":"Toxicology"},{"key":"10.1016\/j.jhazmat.2025.137635_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.134866","article-title":"Plastic takeaway food containers may cause human intestinal damage in routine life usage: Microplastics formation and cytotoxic effect","volume":"475","author":"Jin","year":"2024","journal-title":"J Hazard Mater"},{"issue":"172","key":"10.1016\/j.jhazmat.2025.137635_bib19","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0226-2023","article-title":"Microplastic and plastic pollution: impact on respiratory disease and health","volume":"33","author":"Vasse","year":"2024","journal-title":"Eur Respir Rev: J Eur Respir Soc"},{"issue":"30","key":"10.1016\/j.jhazmat.2025.137635_bib20","doi-asserted-by":"crossref","first-page":"10911","DOI":"10.1021\/acs.est.2c07179","article-title":"Detection of Various Microplastics in Patients Undergoing Cardiac Surgery","volume":"57","author":"Yang","year":"2023","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.jhazmat.2025.137635_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.134878","article-title":"Polystyrene nanoplastics induce lipophagy via the AMPK\/ULK1 pathway and block lipophagic flux leading to lipid accumulation in hepatocytes","volume":"476","author":"Fan","year":"2024","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.171109","article-title":"Revealing new insights: Two-center evidence of microplastics in human vitreous humor and their implications for ocular health","volume":"921","author":"Zhong","year":"2024","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jhazmat.2025.137635_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.170962","article-title":"Microplastic-mediated new mechanism of liver damage: From the perspective of the gut-liver axis","volume":"919","author":"Wang","year":"2024","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jhazmat.2025.137635_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2024.110976","article-title":"A critical review on male-female reproductive and developmental toxicity induced by micro-plastics and nano-plastics through different signaling pathways","volume":"394","author":"Ali","year":"2024","journal-title":"Chem-Biol Interact"},{"key":"10.1016\/j.jhazmat.2025.137635_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122937","article-title":"The alarming link between environmental microplastics and health hazards with special emphasis on cancer","volume":"355","author":"Goswami","year":"2024","journal-title":"Life Sci"},{"key":"10.1016\/j.jhazmat.2025.137635_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149555","article-title":"Overview on the occurrence of microplastics in air and implications from the use of face masks during the COVID-19 pandemic. The","volume":"800","author":"Torres-Agullo","year":"2021","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jhazmat.2025.137635_bib27","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.jtos.2023.08.009","article-title":"TFOS Lifestyle Report Executive Summary: A Lifestyle Epidemic - Ocular Surface Disease","volume":"30","author":"Craig","year":"2023","journal-title":"Ocul Surf"},{"issue":"3","key":"10.1016\/j.jhazmat.2025.137635_bib28","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.jtos.2017.05.003","article-title":"TFOS DEWS II Epidemiology Report","volume":"15","author":"Stapleton","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jhazmat.2025.137635_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.clae.2024.102257","article-title":"Classification of dry eye disease subtypes","author":"Vidal-Rohr","year":"2024","journal-title":"Contact Lens Anterior Eye: J Br Contact Lens Assoc"},{"key":"10.1016\/j.jhazmat.2025.137635_bib30","doi-asserted-by":"crossref","first-page":"1307682","DOI":"10.3389\/fmed.2024.1307682","article-title":"Inflammation mechanism and anti-inflammatory therapy of dry eye","volume":"11","author":"Chu","year":"2024","journal-title":"Front Med"},{"issue":"1","key":"10.1016\/j.jhazmat.2025.137635_bib31","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1167\/iovs.63.1.39","article-title":"A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter","volume":"63","author":"Mu","year":"2022","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jhazmat.2025.137635_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119126","article-title":"Polystyrene microplastic particles: In vivo and in vitro ocular surface toxicity assessment","volume":"303","author":"Zhou","year":"2022","journal-title":"Environ Pollut (Barking, Essex: 1987)"},{"issue":"3","key":"10.1016\/j.jhazmat.2025.137635_bib33","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.jtos.2017.05.001","article-title":"TFOS DEWS II Diagnostic Methodology report","volume":"15","author":"Wolffsohn","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jhazmat.2025.137635_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.142427","article-title":"Interactions between microplastics and organic pollutants: Effects on toxicity, bioaccumulation, degradation, and transport","volume":"748","author":"Wang","year":"2020","journal-title":"Sci Total Environ"},{"issue":"11s","key":"10.1016\/j.jhazmat.2025.137635_bib35","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.ophtha.2017.05.031","article-title":"Meibomian Gland Disease: The Role of Gland Dysfunction in Dry Eye Disease","volume":"124","author":"Chhadva","year":"2017","journal-title":"Ophthalmology"},{"issue":"12","key":"10.1016\/j.jhazmat.2025.137635_bib36","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1001\/jamaophthalmol.2022.4394","article-title":"Prevalence and Incidence of Dry Eye and Meibomian Gland Dysfunction in the United States: A Systematic Review and Meta-analysis","volume":"140","author":"McCann","year":"2022","journal-title":"JAMA Ophthalmol"},{"issue":"5","key":"10.1016\/j.jhazmat.2025.137635_bib37","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/ICO.0b013e318225415a","article-title":"Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study","volume":"31","author":"Lemp","year":"2012","journal-title":"Cornea"},{"issue":"4","key":"10.1016\/j.jhazmat.2025.137635_bib38","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1167\/iovs.10-6997b","article-title":"The international workshop on meibomian gland dysfunction: report of the definition and classification subcommittee","volume":"52","author":"Nelson","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jhazmat.2025.137635_bib39","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ajo.2016.06.025","article-title":"Development of Definitive and Reliable Grading Scales for Meibomian Gland Dysfunction","volume":"169","author":"Arita","year":"2016","journal-title":"Am J Ophthalmol"},{"issue":"12","key":"10.1016\/j.jhazmat.2025.137635_bib40","doi-asserted-by":"crossref","first-page":"5149","DOI":"10.1167\/iovs.18-24690","article-title":"Spontaneous Eye Blink Patterns in Dry Eye: Clinical Correlations","volume":"59","author":"Su","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"(2","key":"10.1016\/j.jhazmat.2025.137635_bib41","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1002\/mds.10065","article-title":"Dry eye, blinking, and blepharospasm","volume":"17","author":"Evinger","year":"2002","journal-title":"Mov Disord"},{"issue":"1","key":"10.1016\/j.jhazmat.2025.137635_bib42","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S1542-0124(11)70007-6","article-title":"Spontaneous eyeblink activity","volume":"9","author":"Cruz","year":"2011","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jhazmat.2025.137635_bib43","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.preteyeres.2014.11.001","article-title":"Dynamics and function of the tear film in relation to the blink cycle","volume":"45","author":"Braun","year":"2015","journal-title":"Prog Retin Eye Res"},{"issue":"3","key":"10.1016\/j.jhazmat.2025.137635_bib44","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.jtos.2019.05.007","article-title":"Evaluation of incomplete blinking as a measurement of dry eye disease","volume":"17","author":"Jie","year":"2019","journal-title":"Ocul Surf"},{"issue":"2","key":"10.1016\/j.jhazmat.2025.137635_bib45","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jtos.2018.03.001","article-title":"Effects of environment pollution on the ocular surface","volume":"16","author":"Jung","year":"2018","journal-title":"Ocul Surf"},{"issue":"4","key":"10.1016\/j.jhazmat.2025.137635_bib46","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1167\/iovs.61.4.23","article-title":"Airborne Particulates Affect Corneal Homeostasis and Immunity","volume":"61","author":"Somayajulu","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.jhazmat.2025.137635_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124536","article-title":"Enhanced hepatic cytotoxicity of chemically transformed polystyrene microplastics by simulated gastric fluid","volume":"410","author":"Wang","year":"2021","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib48","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.envpol.2018.04.017","article-title":"Exposure to nanoplastics disturbs the gut microbiome in the soil oligochaete Enchytraeus crypticus","volume":"239","author":"Zhu","year":"2018","journal-title":"Environ Pollut"},{"key":"10.1016\/j.jhazmat.2025.137635_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2025.121055","article-title":"Downsizing plastics, upsizing impact: How microplastic particle size affects Chironomus riparius bioturbation activity","volume":"270","author":"Sebteoui","year":"2025","journal-title":"Environ Res."},{"key":"10.1016\/j.jhazmat.2025.137635_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.137645","article-title":"Toxic effects of fluoxetine-loaded onto virgin or aged polypropylene, polyamide and polyvinyl chloride microparticles on Daphnia magna","volume":"489","author":"Moura","year":"2025","journal-title":"J Hazard Mater."},{"key":"10.1016\/j.jhazmat.2025.137635_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.scitotenv.2017.11.103","article-title":"Microplastic particles cause intestinal damage and other adverse effects in zebrafish Danio rerio and nematode Caenorhabditis elegans","volume":"619-620","author":"Lei","year":"2018","journal-title":"Sci Total Environ"},{"issue":"12","key":"10.1016\/j.jhazmat.2025.137635_bib52","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/s41575-022-00675-x","article-title":"The role of goblet cells and mucus in intestinal homeostasis","volume":"19","author":"Gustafsson","year":"2022","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"3","key":"10.1016\/j.jhazmat.2025.137635_bib53","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jtos.2017.05.011","article-title":"TFOS DEWS II pathophysiology report","volume":"15","author":"Bron","year":"2017","journal-title":"Ocul Surf"},{"key":"10.1016\/j.jhazmat.2025.137635_bib54","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.scitotenv.2019.05.071","article-title":"An assessment of the toxicity of polypropylene microplastics in human derived cells","volume":"684","author":"Hwang","year":"2019","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.jhazmat.2025.137635_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127861","article-title":"A rapid review and meta-regression analyses of the toxicological impacts of microplastic exposure in human cells","volume":"427","author":"Danopoulos","year":"2022","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2023.104193","article-title":"Current approaches, and challenges on identification, remediation and potential risks of emerging plastic contaminants: A review","volume":"101","author":"Quang","year":"2023","journal-title":"Environ Toxicol Pharmacol"},{"key":"10.1016\/j.jhazmat.2025.137635_bib57","first-page":"1","article-title":"Microplastic sources, formation, toxicity and remediation: a review","author":"Osman","year":"2023","journal-title":"Environ Chem Lett"},{"key":"10.1016\/j.jhazmat.2025.137635_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.121575","article-title":"Polystyrene microplastic particles: In vitro pulmonary toxicity assessment","volume":"385","author":"Dong","year":"2020","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.128980","article-title":"Microplastics released from food containers can suppress lysosomal activity in mouse macrophages","volume":"435","author":"Deng","year":"2022","journal-title":"J Hazard Mater"},{"issue":"Pt A","key":"10.1016\/j.jhazmat.2025.137635_bib60","article-title":"Physiological and metabolic approach of plastic additive effects: Immune cells responses","volume":"404","author":"Burgos-Aceves","year":"2021","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jhazmat.2025.137635_bib61","article-title":"Modulation of Immune Responses by Particle Size and Shape","volume":"11","author":"Baranov","year":"2020","journal-title":"Front Immunol"},{"issue":"8","key":"10.1016\/j.jhazmat.2025.137635_bib62","doi-asserted-by":"crossref","DOI":"10.3390\/biom12081095","article-title":"Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells","volume":"12","author":"Busch","year":"2022","journal-title":"Biomolecules"},{"key":"10.1016\/j.jhazmat.2025.137635_bib63","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1247747","article-title":"Morphological and lipid metabolism alterations in macrophages exposed to model environmental nanoplastics traced by high-resolution synchrotron techniques","volume":"14","author":"Zingaro","year":"2023","journal-title":"Front Immunol"},{"issue":"Pt 2","key":"10.1016\/j.jhazmat.2025.137635_bib64","article-title":"Evaluation of potential toxicity of polyethylene microplastics on human derived cell lines","volume":"838","author":"Gautam","year":"2022","journal-title":"Sci Total Environ"}],"container-title":["Journal of Hazardous Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304389425005497?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304389425005497?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:09:12Z","timestamp":1778684952000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304389425005497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":64,"alternative-id":["S0304389425005497"],"URL":"https:\/\/doi.org\/10.1016\/j.jhazmat.2025.137635","relation":{},"ISSN":["0304-3894"],"issn-type":[{"value":"0304-3894","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of microplastics in human tear fluid and meibum: Implications for dry eye disease pathogenesis","name":"articletitle","label":"Article Title"},{"value":"Journal of Hazardous Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhazmat.2025.137635","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"137635"}}