{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:17:29Z","timestamp":1791080249640,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2004,5,1]],"date-time":"2004-05-01T00:00:00Z","timestamp":1083369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2004,5]]},"DOI":"10.1016\/j.jhep.2004.01.008","type":"journal-article","created":{"date-parts":[[2004,2,7]],"date-time":"2004-02-07T10:16:00Z","timestamp":1076148960000},"page":"774-780","source":"Crossref","is-referenced-by-count":52,"title":["Cellular retinol-binding protein-1 expression in normal and fibrotic\/cirrhotic human liver: different patterns of expression in hepatic stellate cells and (myo)fibroblast subpopulations"],"prefix":"10.1016","volume":"40","author":[{"given":"S\u00e9bastien","family":"Lepreux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulette","family":"Bioulac-Sage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Gabbiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Sapin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Housset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Rosenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Balabaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Desmouli\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2004.01.008_BIB1","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/0014-4827(85)90243-5","article-title":"Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver","volume":"160","author":"Hendriks","year":"1985","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.jhep.2004.01.008_BIB2","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1096\/fasebj.5.3.2001786","article-title":"Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis","volume":"5","author":"Blomhoff","year":"1991","journal-title":"FASEB J"},{"key":"10.1016\/j.jhep.2004.01.008_BIB3","doi-asserted-by":"crossref","first-page":"13560","DOI":"10.1016\/S0021-9258(17)38759-8","article-title":"Hepatic retinol metabolism. Distribution of retinoids, enzymes, and binding proteins in isolated rat liver cells","volume":"260","author":"Blomhoff","year":"1985","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jhep.2004.01.008_BIB4","first-page":"1741","article-title":"Cellular retinol-binding protein-1 is transiently expressed in granulation tissue fibroblasts and differentially expressed in fibroblasts cultured from different organs","volume":"151","author":"Xu","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB5","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/labinvest.3780456","article-title":"Cellular retinol-binding protein-1 expression and modulation during in vivo and in vitro myofibroblastic differentiation of rat hepatic stellate cells and portal fibroblasts","volume":"82","author":"Uchio","year":"2002","journal-title":"Lab Invest"},{"key":"10.1016\/j.jhep.2004.01.008_BIB6","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1002\/hep.1840160623","article-title":"Role of mesenchymal cell populations in porcine serum-induced rat liver fibrosis","volume":"16","author":"Bhunchet","year":"1992","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB7","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s004180050421","article-title":"Localization of liver myofibroblasts and hepatic stellate cells in normal and diseased rat livers: distinct roles of (myo)fibroblast subpopulations in hepatic tissue repair","volume":"112","author":"Knittel","year":"1999","journal-title":"Histochem Cell Biol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB8","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/S0016-5085(99)70407-5","article-title":"Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential","volume":"117","author":"Knittel","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB9","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1034\/j.1600-0676.2002.01726.x","article-title":"Mesenchymal cells in the liver\u2014one cell type or two?","volume":"22","author":"Ramadori","year":"2002","journal-title":"Liver"},{"key":"10.1016\/j.jhep.2004.01.008_BIB10","first-page":"265","article-title":"Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat","volume":"74","author":"Tuchweber","year":"1996","journal-title":"Lab Invest"},{"key":"10.1016\/j.jhep.2004.01.008_BIB11","first-page":"1233","article-title":"Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers","volume":"138","author":"Schmitt-Graff","year":"1991","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB12","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF00194608","article-title":"Immunohistochemical identification of Ito cells and their myofibroblastic transformation in adult human liver","volume":"424","author":"Enzan","year":"1994","journal-title":"Virchows Arch"},{"key":"10.1016\/j.jhep.2004.01.008_BIB13","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/hep.510240201","article-title":"An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group","volume":"24","author":"Bedossa","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB14","first-page":"509","article-title":"Cellular retinol-binding protein-1 is expressed by distinct subsets of rat arterial smooth muscle cells in vitro and in vivo","volume":"150","author":"Neuville","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB15","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1083\/jcb.103.6.2787","article-title":"A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation","volume":"103","author":"Skalli","year":"1986","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB16","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1002\/hep.1840040509","article-title":"Isolation, culture and characterization of adult human hepatocytes from surgical liver biopsies","volume":"4","author":"Ballet","year":"1984","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB17","doi-asserted-by":"crossref","first-page":"6527","DOI":"10.1073\/pnas.92.14.6527","article-title":"Isolation of small polarized bile duct units","volume":"92","author":"Mennone","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jhep.2004.01.008_BIB18","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1038\/labinvest.3780073","article-title":"PDGF-mediated chemoattraction of hepatic stellate cells by bile duct segments in cholestatic liver injury","volume":"80","author":"Kinnman","year":"2000","journal-title":"Lab Invest"},{"key":"10.1016\/j.jhep.2004.01.008_BIB19","first-page":"750","article-title":"Endothelin-1 secretion by human gallbladder epithelial cells in primary culture","volume":"69","author":"Housset","year":"1993","journal-title":"Lab Invest"},{"key":"10.1016\/j.jhep.2004.01.008_BIB20","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S1357-2725(02)00023-7","article-title":"PAV-1, a new rat hepatic stellate cell line converts retinol into retinoic acid, a process altered by ethanol","volume":"34","author":"Sauvant","year":"2002","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB21","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0168-8278(88)80042-4","article-title":"Desmin distinguishes cultured fat-storing cells from myofibroblasts, smooth muscle cells and fibroblasts in the rat","volume":"6","author":"Takase","year":"1988","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB22","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/hep.1840040425","article-title":"Immunocytochemical detection of desmin in fat-storing cells (Ito cells)","volume":"4","author":"Yokoi","year":"1984","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB23","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1002\/hep.510230634","article-title":"Comparison of glial fibrillary acidic protein and desmin staining in normal and CCl4-induced fibrotic rat liver","volume":"23","author":"Niki","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB24","first-page":"449","article-title":"Cell-type-specific expression of neural cell adhesion molecule (N-CAM) in Ito cells of rat liver","volume":"149","author":"Knittel","year":"1996","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB25","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1002\/hep.510290232","article-title":"Class VI intermediate filament protein nestin is induced during activation of rat hepatic stellate cells","volume":"29","author":"Niki","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB26","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/hep.1840190224","article-title":"Ito cell heterogeneity: desmin-negative Ito cells in normal rat liver","volume":"19","author":"Ballardini","year":"1994","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB27","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1083\/jcb.98.5.1696","article-title":"Immunocytochemical studies on the localization of plasma and of cellular retinol-binding proteins and of transthyretin (prealbumin) in rat liver and kidney","volume":"98","author":"Kato","year":"1984","journal-title":"J Cell Biol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB28","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1016\/S0002-9440(10)65501-0","article-title":"Synaptophysin: a novel marker for human and rat hepatic stellate cells","volume":"155","author":"Cassiman","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB29","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1053\/jhep.2001.20793","article-title":"Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors","volume":"33","author":"Cassiman","year":"2001","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB30","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s00428-003-0804-4","article-title":"Vinculin: a novel marker for quiescent and activated hepatic stellate cells in human and rat livers","volume":"443","author":"Kawai","year":"2003","journal-title":"Virchows Arch"},{"key":"10.1016\/j.jhep.2004.01.008_BIB31","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0168-8278(86)80047-2","article-title":"Perisinusoidal cells in patients with normal liver histology. A morphometric study","volume":"2","author":"Sztark","year":"1986","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB32","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0168-8278(01)00260-4","article-title":"Hepatic stellate cell\/myofibroblast subpopulations in fibrotic human and rat livers","volume":"36","author":"Cassiman","year":"2002","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2004.01.008_BIB33","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/0016-5085(84)90143-4","article-title":"Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells","volume":"87","author":"Mak","year":"1984","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB34","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1053\/jhep.2003.50321","article-title":"Cellular retinol-binding protein-1 in hepatocellular carcinoma correlates with beta-catenin. Ki-67 index, and patient survival","volume":"38","author":"Schmitt-Gr\u00e4ff","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.01.008_BIB35","series-title":"The retinoids","first-page":"177","article-title":"Metabolism of retinoids","author":"Frolick","year":"1984"},{"key":"10.1016\/j.jhep.2004.01.008_BIB36","series-title":"Present knowledge in nutrition","first-page":"109","article-title":"Vitamin A","author":"Olson","year":"1996"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827804000200?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827804000200?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T16:58:47Z","timestamp":1623689927000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827804000200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["S0168827804000200"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2004.01.008","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2004,5]]}}}