{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T07:06:03Z","timestamp":1768979163405,"version":"3.49.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1016\/j.jhep.2004.03.013","type":"journal-article","created":{"date-parts":[[2004,4,13]],"date-time":"2004-04-13T10:22:09Z","timestamp":1081851729000},"page":"126-131","source":"Crossref","is-referenced-by-count":81,"title":["Sporadic cases of acute autochthonous hepatitis E in Spain"],"prefix":"10.1016","volume":"41","author":[{"given":"Maria","family":"Buti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar","family":"Clemente-Casares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosend","family":"Jardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meritxell","family":"Formiga-Cruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Schaper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Auristela","family":"Valdes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Rodriguez-Frias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Esteban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosina","family":"Girones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2004.03.013_BIB1","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1002\/hep.1840170525","article-title":"Hepatitis E","volume":"17","author":"Krawczynski","year":"1993","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.03.013_BIB2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1365-2893.1997.00145.x","article-title":"Epidemiology of hepatitis E virus infection","volume":"4","author":"Balayan","year":"1997","journal-title":"J Viral Hep"},{"key":"10.1016\/j.jhep.2004.03.013_BIB3","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1093\/infdis\/169.4.801","article-title":"Determination of hepatitis E virus seroprevalence by using recombinant fusion proteins and synthetic peptides","volume":"169","author":"Paul","year":"1994","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jhep.2004.03.013_BIB4","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.4065\/72.12.1133","article-title":"Acute hepatitis E by a new isolate acquired in the United States","volume":"72","author":"Kwo","year":"1997","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.jhep.2004.03.013_BIB5","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/S0168-8278(00)80316-5","article-title":"HEV identified in serum from humans with acute hepatitis and in sewage of animal origin in Spain","volume":"33","author":"Pina","year":"2000","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB6","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/(SICI)1096-9071(199904)57:4<356::AID-JMV5>3.0.CO;2-D","article-title":"Identification of a novel variant of hepatitis E virus in Italy","volume":"57","author":"Zanetti","year":"1999","journal-title":"J Med Viral"},{"key":"10.1016\/j.jhep.2004.03.013_BIB7","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1159\/000149370","article-title":"Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal\u2013oral route","volume":"20","author":"Balayan","year":"1983","journal-title":"Intervirology"},{"key":"10.1016\/j.jhep.2004.03.013_BIB8","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/S0168-8278(94)80229-7","article-title":"Hepatitis E: intrafamiliar transmission versus waterborne spread","volume":"21","author":"Aggarwal","year":"1994","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB9","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S1386-6346(03)00233-X","article-title":"Present state of hepatitis E virus epidemiology in Tokyo, Japan","volume":"27","author":"Ding","year":"2003","journal-title":"Hepatol Res"},{"key":"10.1016\/j.jhep.2004.03.013_BIB10","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1002\/jmv.2031","article-title":"Genetic heterogeneity of hepatitis E virus","volume":"65","author":"Schlauder","year":"2001","journal-title":"J Med Virol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB11","doi-asserted-by":"crossref","first-page":"9860","DOI":"10.1073\/pnas.94.18.9860","article-title":"A novel virus in swine is closely related to the human hepatitis E virus","volume":"94","author":"Meng","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jhep.2004.03.013_BIB12","doi-asserted-by":"crossref","first-page":"3828","DOI":"10.1128\/JCM.37.12.3828-3834.1999","article-title":"Identity of a novel swine hepatitis E virus in Taiwan forming a monophyletic group with Taiwan isolates from human hepatitis E virus","volume":"37","author":"Hsieh","year":"1999","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB13","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1128\/JCM.40.1.117-122.2002","article-title":"Prevalence of antibodies to hepatitis E virus in veterinarians working with swine and in normal blood donors in the United States and other countries","volume":"40","author":"Meng","year":"2002","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB14","doi-asserted-by":"crossref","first-page":"448","DOI":"10.3201\/eid0904.020351","article-title":"Hepatitis E virus epidemiology in industrialized countries","volume":"9","author":"Clemente-Casares","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.jhep.2004.03.013_BIB15","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1128\/JCM.28.3.495-503.1990","article-title":"Rapid and sensitive method for the detection of nucleic acids","volume":"28","author":"Boom","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB16","doi-asserted-by":"crossref","first-page":"4485","DOI":"10.1128\/AEM.64.11.4485-4488.1998","article-title":"Characterization of a strain of infectious hepatitis E virus isolated from sewage in an area where hepatitis E is not endemic","volume":"64","author":"Pina","year":"1998","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB17","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0166-0934(99)00052-X","article-title":"Rapid detection of hepatitis E virus RNA by reverse transcription-polymerase chain reaction using universal oligonucleotide primers","volume":"81","author":"Erker","year":"1999","journal-title":"J Virol Methods"},{"key":"10.1016\/j.jhep.2004.03.013_BIB18","first-page":"357","article-title":"TREEVIEW: an application to display phylogenetic trees on personal computers","volume":"12","author":"Page","year":"1996","journal-title":"Comput Appl Biosci"},{"key":"10.1016\/j.jhep.2004.03.013_BIB19","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1099\/0022-1317-79-3-447","article-title":"The sequence and phylogenetic analysis of a novel hepatitis E virus isolated from a patient with acute hepatitis reported in the United States","volume":"79","author":"Schlauder","year":"1998","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB20","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1099\/0022-1317-80-1-169","article-title":"A divergent genotype of hepatitis E virus in chinese patients with acute hepatitis","volume":"80","author":"Wang","year":"1999","journal-title":"J Gen Virol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB21","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1128\/JCM.32.9.2060-2066.1994","article-title":"Persistent and transient antibody responses to hepatitis E virus detected by western immunoblot using open reading frame 2 and 3 and glutathione S-transferase fusion proteins","volume":"32","author":"Li","year":"1994","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB22","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0166-0934(95)00044-U","article-title":"Hepatitis E virus in acute hepatitis in Spain","volume":"55","author":"Buti","year":"1995","journal-title":"J Virol Methods"},{"key":"10.1016\/j.jhep.2004.03.013_BIB23","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0923-2516(07)80007-0","article-title":"Hepatitis type in a French population: detection of anti-HEV by a synthetic peptide-based enzyme-linked immunosorbent assay","volume":"145","author":"Coursaget","year":"1994","journal-title":"Res Virol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB24","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S0168-8278(05)80341-1","article-title":"Epidemiology and serologic diagnosis of hepatitis E","volume":"20","author":"Lok","year":"1994","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB25","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1086\/345439","article-title":"Cluster of cases of acute hepatitis associated with hepatitis E virus infection acquired in The Netherlands","volume":"36","author":"Widdowson","year":"2003","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jhep.2004.03.013_BIB26","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1093\/infdis\/172.4.927","article-title":"Viremia, fecal shedding, and IgM and IgA responses in patients with hepatitis E","volume":"172","author":"Clayson","year":"1995","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jhep.2004.03.013_BIB27","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1002\/hep.510270331","article-title":"Evaluation of assays for antibody to hepatitis E virus by a serum panel","volume":"27","author":"Mast","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.03.013_BIB28","doi-asserted-by":"crossref","first-page":"670A","DOI":"10.1016\/S0270-9139(03)81105-9","article-title":"Acute hepatitis E: a study of 17 consecutive patients in south-west France over a 13 month period","volume":"38","author":"Poirson","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2004.03.013_BIB29","article-title":"An outbreak of hepatitis E in group members who ingested wild boar meat","author":"Tamada","year":"2004","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2004.03.013_BIB30","series-title":"Fields virology","first-page":"2831","article-title":"Hepatitis E virus","author":"Purcell","year":"1996"},{"key":"10.1016\/j.jhep.2004.03.013_BIB31","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1046\/j.1423-0410.1999.7620078.x","article-title":"Hepatitis E virus: relevance in blood donors and risk groups","volume":"76","author":"Mateos","year":"1999","journal-title":"Vox Sang"},{"key":"10.1016\/j.jhep.2004.03.013_BIB32","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/0140-6736(93)90873-F","article-title":"Hepatitis E and long-term antibody status","volume":"341","author":"Khuroo","year":"1993","journal-title":"Lancet"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827804001308?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827804001308?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T23:54:26Z","timestamp":1585698866000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827804001308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["S0168827804001308"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2004.03.013","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2004,7]]}}}