{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T04:29:23Z","timestamp":1780806563825,"version":"3.54.1"},"reference-count":98,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":2023,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2008]]},"DOI":"10.1016\/j.jhep.2008.01.010","type":"journal-article","created":{"date-parts":[[2008,2,6]],"date-time":"2008-02-06T09:00:55Z","timestamp":1202288455000},"page":"S93-S103","source":"Crossref","is-referenced-by-count":83,"special_numbering":"S1","title":["Pathogenesis and management of hepatorenal syndrome in patients with cirrhosis"],"prefix":"10.1016","volume":"48","author":[{"given":"Paolo","family":"Angeli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Merkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2008.01.010_bib1","first-page":"570","article-title":"A liver and kidney syndrome: clinical, pathological, and experimental studies","volume":"55","author":"Helvig","year":"1932","journal-title":"Surg Gynecol Obstet"},{"key":"10.1016\/j.jhep.2008.01.010_bib2","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/S0140-6736(56)90149-0","article-title":"Electrolyte and circulatory changes in terminal liver failure","volume":"2","author":"Hecker","year":"1956","journal-title":"Lancet"},{"key":"10.1016\/j.jhep.2008.01.010_bib3","first-page":"41","article-title":"The hepato-renal syndrome","volume":"4","author":"Papper","year":"1975","journal-title":"Clin Nephrol"},{"key":"10.1016\/j.jhep.2008.01.010_bib4","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1056\/NEJM196906192802501","article-title":"Transplantation of cadaveric kidneys from patients with hepato-renal syndrome: evidence for the functional nature of renal failure in advanced liver disease","volume":"280","author":"Koppel","year":"1969","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jhep.2008.01.010_bib5","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0002-9343(70)80073-0","article-title":"Renal failure in the patient with cirrhosis. The role of active vasoconstriction","volume":"49","author":"Epstein","year":"1970","journal-title":"Am J Med"},{"key":"10.1016\/j.jhep.2008.01.010_bib6","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/hep.510230122","article-title":"Definition and diagnostic criteria of refractory ascites and hepato-renal syndrome in cirrhosis","volume":"23","author":"Arroyo","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib7","first-page":"1310","article-title":"Diagnosis, prevention and treatment of the hepato-renal syndrome in cirrhosis","volume":"56","author":"Salerno","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2008.01.010_bib8","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1056\/NEJM198506203122504","article-title":"The Will Rogers phenomenon. Stage migration and new diagnostic techniques as a source of misleading statistics for survival in cancer","volume":"312","author":"Feinstein","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jhep.2008.01.010_bib9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1053\/jhep.2003.50084","article-title":"Acute renal failure in patients with cirrhosis: perspectives in the age of MELD","volume":"37","author":"Moreau","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib10","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0016-5085(93)90031-7","article-title":"Incidence, predictive factors and prognosis of the hepato-renal syndrome in cirrhosis with ascites","volume":"105","author":"Gines","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib11","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1002\/hep.1840080532","article-title":"Peripheral arteriolar vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis","volume":"8","author":"Schrier","year":"1988","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib12","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1016\/S0140-6736(03)14903-3","article-title":"Hepato-renal syndrome","volume":"362","author":"Gines","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.jhep.2008.01.010_bib13","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1002\/hep.1840200619","article-title":"Renal impairment after spontaneous bacterial peritonitis in cirrhosis: incidence, clinical course, predictive factors and prognosis","volume":"20","author":"Follo","year":"1994","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib14","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1365-2036.2006.02706.x","article-title":"Switch therapy with ciprofloxacin versus intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis:similar efficacy at lower cost","volume":"23","author":"Angeli","year":"2006","journal-title":"Alimentary Pharmacol Ther"},{"key":"10.1016\/j.jhep.2008.01.010_bib15","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/hep.21443","article-title":"Renal failure and bacterial infections in patients with cirrhosis: epidemiology and clinical features","volume":"45","author":"Fasolato","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib16","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1053\/j.gastro.2005.09.024","article-title":"Renal failure in patients with cirrhosis and sepsis unrelated to spontaneous bacterial peritonitis: value of MELD score","volume":"129","author":"Terra","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib17","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1365-2362.1983.tb00100.x","article-title":"Sympathetic nervous activity, renin\u2013angiotensin system and renal excretion of prostaglandin E2 in cirrhosis. Relationship to functional renal failure and sodium and water excretion","volume":"13","author":"Arroyo","year":"1983","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.jhep.2008.01.010_bib18","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1055\/s-2007-1007296","article-title":"Hepato-renal disorders: role of the sympathetic nervous system","volume":"14","author":"Henriksen","year":"1994","journal-title":"Sem Liver Dis"},{"key":"10.1016\/j.jhep.2008.01.010_bib19","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/0016-5085(93)90431-B","article-title":"Effects of low-dose captopril on renal hemodynamics and function in patients with cirrhosis of the liver","volume":"104","author":"Gentilini","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib20","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0168-8278(87)80569-X","article-title":"Effects of lumbar sympathetic block on kidney function in cirrhotic patients with hepato-renal syndrome","volume":"5","author":"Solis-Herruzo","year":"1987","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib21","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1097\/00042737-199708000-00012","article-title":"Relationship between splanchnic, peripheral and cardiac haemodynamics in liver cirrhosis of different degrees of severity","volume":"9","author":"Piscaglia","year":"1997","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib22","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1016\/0016-5085(89)91704-6","article-title":"Systemic and regional hemodynamics in patients with liver cirrhosis and ascites with and without functional renal failure","volume":"97","author":"Fernandez-Seara","year":"1989","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib23","first-page":"788","article-title":"Brachial and femoral artery blood flow in cirrhosis: relationship to kidney dysfunction","volume":"17","author":"Maroto","year":"1993","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib24","first-page":"219","article-title":"Renal vasoconstriction in cirrhosis evaluated by duplex ultrasonography","volume":"17","author":"Sacerdoti","year":"1993","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib25","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1097\/00042737-199511000-00012","article-title":"Middle cerebral artery blood flow velocity in patients with cirrhosis","volume":"7","author":"Dillon","year":"1995","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib26","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1002\/hep.510280510","article-title":"Reduction of renal cortical blood flow assessed by Doppler in cirrhotic patients with refractory ascites","volume":"28","author":"Rivolta","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib27","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/hep.510280107","article-title":"Increased cerebrovascular resistance in cirrhotic patients with ascites","volume":"28","author":"Guevara","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib28","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0168-8278(00)00035-0","article-title":"Postprandial middle cerebral arterial vasoconstriction in cirrhotic patients. A placebo controlled evaluation","volume":"34","author":"Sugano","year":"2001","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib29","series-title":"Ascites and renal dysfunction in liver disease","first-page":"139","article-title":"The systemic circulation in cirrhosis","author":"Moller","year":"2005"},{"key":"10.1016\/j.jhep.2008.01.010_bib30","first-page":"83","article-title":"Noninvasive measurement of femoral blood flow and portal pressure response to propranolol in patients with cirrhosis","volume":"21","author":"Luca","year":"1995","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib31","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1177\/000331979204301202","article-title":"Capillary blood flow in the skin of forearm in cirrhosis","volume":"43","author":"Carella","year":"1992","journal-title":"Angiology"},{"key":"10.1016\/j.jhep.2008.01.010_bib32","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0008-6363(98)00008-X","article-title":"Peripheral vascular tone in patients with cirrhosis: role of the rennin\u2013angiotensin and sympathetic nervous systems","volume":"38","author":"Newby","year":"1998","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.jhep.2008.01.010_bib33","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/hep.510230211","article-title":"Cirrhosis and muscle cramps: evidence of a causal relationship","volume":"23","author":"Angeli","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib34","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1053\/jhep.2002.31432","article-title":"The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough","volume":"35","author":"Wiest","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib35","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1124\/jpet.106.116665","article-title":"Carbon monoxide-mediated activation of large conductance calcium-activated potassium channels contributes to mesenteric vasodilation in cirrhotic rats","volume":"321","author":"Bolognesi","year":"2007","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.jhep.2008.01.010_bib36","first-page":"G274","article-title":"Effect of somatostatin on mesenteric vascular resistance in normal and portal hypertensive rats","volume":"262","author":"Sieber","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jhep.2008.01.010_bib37","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1053\/gast.1996.v110.pm8613060","article-title":"Acute and chronic cyclooxygenase blockade in portal-hypertensive rats: influence on nitric oxide biosynthesis","volume":"110","author":"Fernandez","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib38","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/S0016-5085(98)70486-X","article-title":"Increased adrenomedullin levels in cirrhosis: relationship with hemodynamic abnormalities and vasoconstrictor systems","volume":"114","author":"Guevara","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib39","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1053\/gast.2002.30305","article-title":"Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat","volume":"122","author":"Ros","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib40","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1478-3231.2005.01092.x","article-title":"The role of nitric oxide in the pathogenesis of systemic and splanchnic vasodilation in cirrhotic rats before and after the onset of ascites","volume":"29","author":"Angeli","year":"2005","journal-title":"Liver"},{"key":"10.1016\/j.jhep.2008.01.010_bib41","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1002\/hep.510280407","article-title":"Acute effects of an oral administration of midodrine an \u03b1-adrenergic agonist, on renal hemodynamics and renal function in cirrhotic patients with ascites","volume":"28","author":"Angeli","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib42","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1172\/JCI105679","article-title":"Systemic and renal hemodynamics in oliguric hepatic failure: effect of volume expansion","volume":"46","author":"Tristani","year":"1967","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jhep.2008.01.010_bib43","first-page":"301","article-title":"Splanchnic hemodynamic factors in cirrhosis with refractory ascites","volume":"93","author":"Lebrec","year":"1979","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.jhep.2008.01.010_bib44","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1080\/00365510410002788","article-title":"Volume adaptation in chronic liver disease: on the static and dynamic location of water, salt, protein and red cells in cirrhosis","volume":"64","author":"Henriksen","year":"2004","journal-title":"Scand J Clin Invest"},{"key":"10.1016\/j.jhep.2008.01.010_bib45","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1053\/jhep.2003.50447","article-title":"Systemic, renal and hepatic haemodynamic derangement in cirrhotic patients with spontaneous bacterial peritonitis","volume":"38","author":"Ruiz del Arbol","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib46","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/hep.20766","article-title":"Circulatory function and hepato-renal syndrome","volume":"42","author":"Ruiz del Arbol","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib47","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/hep.21101","article-title":"Adrenal insufficiency in patients with cirrhosis, severe sepsis and septic shock","volume":"43","author":"Tsai","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib48","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1002\/hep.21352","article-title":"Adrenal insufficiency in patients with cirrhosis and septic shock: effect of treatment with hydrocortisone on survival","volume":"44","author":"Fernandez","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib49","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/hep.510240226","article-title":"Cirrhotic cardiomyopathy: getting to the heart of the matter","volume":"24","author":"Ma","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib50","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1136\/gut.47.2.288","article-title":"Long-term outcome after transjugular intrahepatic portosystemic stent\u2013shunt in non-transplant cirrhotics with hepato-renal syndrome: a phase II study","volume":"47","author":"Bresing","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2008.01.010_bib51","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1016\/S0140-6736(96)91667-0","article-title":"Amelioration of hepato-renal syndrome with selective endothelin-A antagonist","volume":"347","author":"Soper","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.jhep.2008.01.010_bib52","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/hep.21940","article-title":"Lack of renal improvement with non selective endothelin antagonism with tezosentan in type 2 hepato-renal syndrome","volume":"47","author":"Wong","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib53","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0168-8278(86)80154-4","article-title":"Urinary excretion of 6-keto-prostaglandin F1\u03b1, thromboxane B2 and prostaglandin E2 in cirrhosis with ascites","volume":"3","author":"Rimola","year":"1986","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib54","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/0016-5085(83)90133-6","article-title":"Urinary thromboxane B2 and prostaglandin E2 in the hepato-renal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors","volume":"84","author":"Zipster","year":"1983","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib55","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0168-8278(90)90123-9","article-title":"Increased production of cysteinyl leukotrienes in hepato-renal syndrome","volume":"11","author":"Moore","year":"1990","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib56","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1172\/JCI119640","article-title":"Eicosanoid excretion in hepatic cirrhosis. Predominance of 20-HETE","volume":"100","author":"Sacerdoti","year":"1997","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jhep.2008.01.010_bib57","first-page":"915","article-title":"Role of nitric oxide and prostacyclin in the control of renal perfusion in experimental cirrhosis","volume":"22","author":"Ros","year":"1995","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib58","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1002\/hep.1840200425","article-title":"Renal effects of endogenous natriuretic peptides receptors blockade in cirrhotic rats with ascites","volume":"20","author":"Angeli","year":"1994","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib59","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/0016-5085(86)90091-0","article-title":"Effects of sulindac and ibuprofen in patients with cirrhosis and ascites. An explanation for the renal-sparing effect of sulindac","volume":"90","author":"Laffi","year":"1986","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib60","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/00007890-199502150-00010","article-title":"Impact of pretransplant renal function on survival after liver transplantation","volume":"59","author":"Gonwa","year":"1995","journal-title":"Transplantation"},{"key":"10.1016\/j.jhep.2008.01.010_bib61","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/hep.1840170302","article-title":"Hemodynamic and humoral changes after liver-transplantation in patients with cirrhosis","volume":"17","author":"Navasa","year":"1993","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib62","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0140-6736(00)04055-1","article-title":"Replacement of calcineurin inhibitors with mycophenolate mofetil in liver-transplant patients with renal dysfunction: a randomised controlled study","volume":"357","author":"Schlitt","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.jhep.2008.01.010_bib63","first-page":"140","article-title":"Effects of treatment of hepato-renal syndrome before transplantation on posttransplantation outcome. A case control study","volume":"40","author":"Restuccia","year":"2004","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhep.2008.01.010_bib64","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/hep.510280219","article-title":"Transjugular intrahepatic portosystemic shunt in hepato-renal syndrome: effects on renal function and vasoactive systems","volume":"28","author":"Guevara","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib65","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/hep.510270107","article-title":"Reversibility of hepato-renal syndrome by prolonged administration of ornipressin and plasma volume expansion","volume":"27","author":"Guevara","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib66","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/hep.510300430","article-title":"Long-term therapy and retreatment of hepato-renal syndrome type 1 with ornipressin and albumin","volume":"30","author":"Gilberg","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib67","first-page":"1054","article-title":"Hepato-renal syndrome: long-term treatment with terlipressin as bridge to liver transplantation","volume":"41","author":"Ganne-Carrie","year":"1996","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jhep.2008.01.010_bib68","first-page":"268","article-title":"Treatment with terlipressin as a bridge to transplantation in a patient with hepato-renal syndrome","volume":"61","author":"Le Moine","year":"1998","journal-title":"Acta Gastroenterol Belg"},{"key":"10.1016\/j.jhep.2008.01.010_bib69","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1111\/j.1572-0241.2000.03214.x","article-title":"Hepato-renal syndrome in cirrhotic patients: terlipressin is a safe and efficient treatment; propranolol and digitalic treatment: precipitating and preventing factors?","volume":"95","author":"Duhamel","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jhep.2008.01.010_bib70","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1097\/00042737-200202000-00009","article-title":"Effect of terlipressin (glypressin) on hepato-renal syndrome in cirrhotic patients: results of a multicenter pilot study","volume":"14","author":"Halimi","year":"2002","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib71","first-page":"15","article-title":"Long-term terlipressin administration improves renal function in cirrhotic patients with type 1 hepato-renal syndrome: a pilot study","volume":"64","author":"Mulkay","year":"2001","journal-title":"Acta Gastroelerologica Belg"},{"key":"10.1016\/j.jhep.2008.01.010_bib72","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0168-8278(00)80158-0","article-title":"Terlipressin plus albumin infusion: an effective and safe therapy of hepato-renal syndrome","volume":"33","author":"Uriz","year":"2000","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib73","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1053\/jhep.2002.35819","article-title":"Terlipressin therapy with and without albumin for patients with hepato-renal syndrome: results of a prospective, nonrandomized study","volume":"36","author":"Ortega","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib74","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1046\/j.1440-1746.2003.02934.x","article-title":"Beneficial effects of terlipressin in hepato-renal syndrome: a prospective, randomized placebo-controlled clinical trial","volume":"18","author":"Solanki","year":"2003","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib75","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1053\/gast.2002.32364","article-title":"Terlipressin in patients with cirrhosis and type 1 hepato-renal syndrome: a retrospective multicenter study","volume":"122","author":"Moreau","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib76","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1002\/hep.510290629","article-title":"Reversal of type 1 hepato-renal syndrome (HRS) with the combined administration of midodrine and octreotide","volume":"29","author":"Angeli","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib77","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1046\/j.1440-1746.2002.02816.x","article-title":"Clinical course, predictive factors and prognosis in patients with cirrhosis and type 1 hepato-renal syndrome treated with terlipressin: a retrospective analysis","volume":"17","author":"Colle","year":"2002","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib78","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/hep.20262","article-title":"Midodrine, octreotide, albumin, and TIPS in selected patients with cirrhosis and type 1 hepato-renal syndrome","volume":"40","author":"Wong","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib79","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1007\/s10620-006-9312-0","article-title":"Octretide\/midodrine therapy significantly improves renal function and 30-day survival in patients with type 1 hepato-renal syndrome","volume":"52","author":"Esrailian","year":"2007","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jhep.2008.01.010_bib80","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1053\/jhep.2002.34343","article-title":"Effects of noradrenalin and albumin in patients with type 1 hepato-renal syndrome: a pilot study","volume":"36","author":"Duvoux","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib81","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.jhep.2007.02.001","article-title":"Advances in the pathogenesis and treatment of type 1 and type 2 hepato-renal syndrome","volume":"46","author":"Arroyo","year":"2007","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib82","first-page":"494A","article-title":"A prospective randomized double blind placebo-controlled trial of terlipressin for Type 1 hepato-renal syndrome (HRS)","volume":"44","author":"Sanyal","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib83","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1016\/S0168-8278(07)61680-8","article-title":"Randomized comparative study of terlipressin and albumin vs albumin alone in patients with cirrhosis and hepato-renal syndrome","volume":"46","author":"Martin-Llahi","year":"2007","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib84","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1053\/lv.2000.6355","article-title":"Improvement of hepato-renal syndrome with extracorporeal albumin dialysis MARS: results on a prospective, randomized controlled clinical trial","volume":"6","author":"Mitzner","year":"2000","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhep.2008.01.010_bib85","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2036.2004.02113.x","article-title":"Review article: prognosis of hepato-renal syndrome \u2013 has it changed with current practice?","volume":"20","author":"Angeli","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.jhep.2008.01.010_bib86","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0168-8278(96)80065-1","article-title":"Transjugular intrahepatic portosystemic shunts: comparison with paracentesis in patients with cirrhosis and refractory ascites","volume":"25","author":"Lebrec","year":"1996","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib87","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1056\/NEJM200006083422303","article-title":"A comparison of paracentesis and transjugular intrahepatic portosystemic shunting in patients with ascites","volume":"342","author":"Rossle","year":"2000","journal-title":"N Eng J Med"},{"key":"10.1016\/j.jhep.2008.01.010_bib88","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1053\/gast.2002.37073","article-title":"Transjugular intrahepatic portosystemic shunting versus paracentesis plus albumin for refractory ascites in cirrhosis","volume":"123","author":"Gines","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib89","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1053\/gast.2003.50088","article-title":"The North American Study for the treatment of refractory ascites","volume":"124","author":"Sanyal","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib90","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/hep.20364","article-title":"Randomized controlled study of TIPS versus paracentesis plus albumin in cirrhosis with severe ascites","volume":"40","author":"Salerno","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.01.010_bib91","first-page":"CD004889","article-title":"TIPS versus paracentesis for cirrhotic patients with refractory ascites","volume":"3","author":"Saab","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jhep.2008.01.010_bib92","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1053\/j.gastro.2005.07.031","article-title":"Uncovered transjugular intrahepatic portosystemic shunt for refractory ascites: a meta-analysis","volume":"129","author":"D\u2019Amico","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib93","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1053\/j.gastro.2007.06.020","article-title":"Transjugular intrahepatic portosystemic shunt for refractory ascites: a meta-analysis of individual patient data","volume":"133","author":"Salerno","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib94","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1097\/00042737-200212000-00013","article-title":"Renal failure in cirrhotic patients: role of terlipressin in clinical approach to hepato-renal syndrome type 2","volume":"14","author":"Alessandria","year":"2002","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib95","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1053\/j.gastro.2007.06.065","article-title":"Primary prophylaxis of spontaneous bacterial peritonitis delays hepato-renal syndrome and improves survival in cirrhosis","volume":"133","author":"Fernandez","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.01.010_bib96","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJM199908053410603","article-title":"Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis","volume":"341","author":"Sort","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jhep.2008.01.010_bib97","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.jhep.2004.05.009","article-title":"Effect of intravenous albumin on systemic and hepatic hemodynamics and vasoactive neurohormonal systems in patients with cirrhosis and spontaneous bacterial peritonitis","volume":"41","author":"Fernandez","year":"2004","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2008.01.010_bib98","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1046\/j.1365-2036.16.s5.2.x","article-title":"Review article: albumin as a drug-biological effects of albumin unrelated to oncotic pressure","volume":"16","author":"Evans","year":"2002","journal-title":"Aliment Pharmacol Ther"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827808000561?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827808000561?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T15:00:04Z","timestamp":1557241204000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827808000561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":98,"alternative-id":["S0168827808000561"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2008.01.010","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2008]]}}}