{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T06:02:14Z","timestamp":1779256934237,"version":"3.51.4"},"reference-count":38,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.jhep.2008.10.026","type":"journal-article","created":{"date-parts":[[2008,12,27]],"date-time":"2008-12-27T09:08:10Z","timestamp":1230368890000},"page":"548-554","source":"Crossref","is-referenced-by-count":45,"title":["Mouse mammary tumour virus-like virus (MMTV-LV) is present within the liver in a wide range of hepatic disorders and unrelated to nuclear p53 expression or hepatocarcinogenesis"],"prefix":"10.1016","volume":"50","author":[{"given":"Harpreet","family":"Johal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gillian","family":"Marie Scott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Camaris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Riordan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.","family":"Rawlinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2008.10.026_bib1","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0140-6736(97)05419-6","article-title":"Primary biliary cirrhosis","volume":"350","author":"Neuberger","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.jhep.2008.10.026_bib2","doi-asserted-by":"crossref","first-page":"8654","DOI":"10.1073\/pnas.85.22.8654","article-title":"Identification and analysis of the major M2 autoantigens in primary biliary cirrhosis","volume":"85","author":"Fussey","year":"1988","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jhep.2008.10.026_bib3","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1016\/S0140-6736(97)10290-2","article-title":"Detection of retroviral antibodies in primary biliary cirrhosis and other idiopathic biliary disorders","volume":"351","author":"Mason","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.jhep.2008.10.026_bib4","doi-asserted-by":"crossref","first-page":"8454","DOI":"10.1073\/pnas.1433063100","article-title":"Does a betaretrovirus infection trigger primary biliary cirrhosis?","volume":"11","author":"Xu","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jhep.2008.10.026_bib5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/hep.20024","article-title":"Cloning the human betaretrovirus proviral genome from patients with primary biliary cirrhosis","volume":"39","author":"Xu","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2008.10.026_bib6","doi-asserted-by":"crossref","unstructured":"Mason A. Viral induction of type 2 diabetes and autoimmune liver disease. In: Emerging role of pathogens in chronic diseases requiring nutritional intervention. Orlando, FL; 2001. p. 2805S\u20132808S.","DOI":"10.1093\/jn\/131.10.2805S"},{"key":"10.1016\/j.jhep.2008.10.026_bib7","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1111\/j.1572-0241.2004.40741.x","article-title":"Pilot studies of single and combination antiretroviral therapy in patients with primary biliary cirrhosis","volume":"99","author":"Mason","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jhep.2008.10.026_bib8","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1126\/science.84.2172.162","article-title":"Some possible effects of nursing on the mammary gland tumour incidence in mice","volume":"84","author":"Bittner","year":"1936","journal-title":"Science"},{"key":"10.1016\/j.jhep.2008.10.026_bib9","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1126\/science.95.2470.462","article-title":"The milk influence of breast tumour in mice","volume":"95","author":"Bittner","year":"1942","journal-title":"Science"},{"key":"10.1016\/j.jhep.2008.10.026_bib10","doi-asserted-by":"crossref","first-page":"10237","DOI":"10.1093\/nar\/16.21.10237","article-title":"A model for hormone receptor binding to the mouse mammary tumour virus regulatory element based on hydroxyl radical footprinting","volume":"16","author":"Chalepakis","year":"1988","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib11","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/229627a0","article-title":"Neutralisation of murine mammary tumour virus by sera of women with breast cancer","volume":"229","author":"Charney","year":"1971","journal-title":"Nature"},{"key":"10.1016\/j.jhep.2008.10.026_bib12","first-page":"1348","article-title":"Formal discussion of multiple factors in mouse mammary tumourigenesis","volume":"25","author":"DeOme","year":"1965","journal-title":"Cancer Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1128\/JVI.49.1.92-101.1984","article-title":"Amplification and novel locations of mouse mammary tumour virus genomes in mouse T-cell lymphomas","volume":"49","author":"Dudley","year":"1984","journal-title":"J Virol"},{"key":"10.1016\/j.jhep.2008.10.026_bib14","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0042-6822(83)90479-8","article-title":"Expression and disposition of the murine mammary tumour virus (MuMTV) envelope gene products by murine mammary tumour cells","volume":"126","author":"Sarkar","year":"1983","journal-title":"Virology"},{"key":"10.1016\/j.jhep.2008.10.026_bib15","doi-asserted-by":"crossref","first-page":"4417","DOI":"10.1158\/1078-0432.CCR-03-0232","article-title":"Mouse mammary tumour-like virus is associated with p53 nuclear accumulation and progesterone receptor positivity but not estrogen positivity in human female breast cancer","volume":"10","author":"Faedo","year":"2004","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib16","doi-asserted-by":"crossref","first-page":"7284","DOI":"10.1158\/1078-0432.CCR-04-0767","article-title":"Mouse mammary tumour virus-like RNA transcripts and DNA are found in affected cells of human breast cancer","volume":"10","author":"Ford","year":"2004","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib17","first-page":"1118","article-title":"Mouse mammary tumour virus-like gene sequences in breast tumours of Australian and Vietnamese women","volume":"9","author":"Ford","year":"2003","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib18","first-page":"844","article-title":"Study of mouse mammary tumour virus-like gene sequences expressing in breast tumours of Chinese women","volume":"37","author":"Luo","year":"2006","journal-title":"Sichuan Da Xue Xue Bao Yi Xue Ban"},{"key":"10.1016\/j.jhep.2008.10.026_bib19","first-page":"323","article-title":"Detection of murine mammary tumour virus (MMTV) env gene-like sequences in breast cancer from Argentine patients","volume":"62","author":"Melana","year":"2002","journal-title":"Medicina"},{"key":"10.1016\/j.jhep.2008.10.026_bib20","first-page":"2565","article-title":"Expression of mouse mammary tumour virus-like env gene sequences in human breast cancer","volume":"4","author":"Wang","year":"1998","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib21","first-page":"5173","article-title":"Detection of mammary tumour virus env gene-like sequences in human breast cancer","volume":"55","author":"Wang","year":"1995","journal-title":"Cancer Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib22","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s007050170201","article-title":"MMTV-like env gene sequences in human breast cancer","volume":"146","author":"Wang","year":"2001","journal-title":"Arch Virol"},{"key":"10.1016\/j.jhep.2008.10.026_bib23","first-page":"1041","article-title":"Detection of MMTV-like LTR and LTR-env gene sequences in human breast cancer","volume":"18","author":"Wang","year":"2001","journal-title":"Int J Oncol"},{"key":"10.1016\/j.jhep.2008.10.026_bib24","first-page":"1754","article-title":"Identification of a proviral structure in human breast cancer","volume":"61","author":"Liu","year":"2001","journal-title":"Cancer Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib25","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1385\/MO:20:3:233","article-title":"High prevalence of MMTV-like env gene sequences in gestational breast cancer","volume":"20","author":"Wang","year":"2003","journal-title":"Medical Oncol"},{"key":"10.1016\/j.jhep.2008.10.026_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1023\/B:BREA.0000041573.09142.00","article-title":"Elevated expression of the tumour suppressing protein p53 is associated with the presence of mouse mammary tumour-like env gene sequences (MMTV-like) in human breast cancer","volume":"87","author":"Lawson","year":"2004","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.jhep.2008.10.026_bib27","series-title":"Competitive PCR for quantitation of mRNA: PCR protocols: a guide to methods and applications","author":"Gilliland","year":"1990"},{"key":"10.1016\/j.jhep.2008.10.026_bib28","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1093\/molbev\/msm092","article-title":"MEGA 4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0","volume":"24","author":"Tamura","year":"2007","journal-title":"Mol Biol Evol"},{"key":"10.1016\/j.jhep.2008.10.026_bib29","unstructured":"SPSS for Windows. In. 14.0.0 ed. Chicago: SPSS Inc.; 2005."},{"key":"10.1016\/j.jhep.2008.10.026_bib30","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1053\/j.gastro.2004.05.033","article-title":"Lack of immunological or molecular evidence for a role of mouse mammary tumour retrovirus in primary biliary cirrhosis","volume":"127","author":"Selmi","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2008.10.026_bib31","first-page":"283","article-title":"Search for Mouse mammary tumour virus-like env sequences in cancer and normal breast from the same individuals","volume":"7","author":"Melana","year":"2001","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jhep.2008.10.026_bib32","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0022-4731(78)90154-1","article-title":"Estradiol receptors in human liver","volume":"9","author":"Duffy","year":"1978","journal-title":"J Steroid Biochem"},{"key":"10.1016\/j.jhep.2008.10.026_bib33","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1038\/modpathol.3800458","article-title":"p53, Ki-67 and serum alpha-feto-protein as predictors of hepatocellular carcinoma recurrence in liver transplant patients","volume":"18","author":"Guzman","year":"2005","journal-title":"Mod Pathol"},{"key":"10.1016\/j.jhep.2008.10.026_bib34","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1038\/sj.onc.1210279","article-title":"TP53 mutations and hepatocellular carcinoma: insights into the aetiology and pathogenesis of liver cancer","volume":"26","author":"Hussain","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.jhep.2008.10.026_bib35","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1038\/381643a0","article-title":"Cell cycle control and its watchman","volume":"381","author":"Jacks","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.jhep.2008.10.026_bib36","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1002\/1097-0142(19950515)75:10<2420::AID-CNCR2820751006>3.0.CO;2-6","article-title":"p53 expression in patients with and without hepatocellular carcinoma","volume":"75","author":"Livni","year":"1995","journal-title":"Cancer"},{"key":"10.1016\/j.jhep.2008.10.026_bib37","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1016\/j.bcp.2004.06.033","article-title":"Influence of p53 and caspase 3 activity on cell death and senescence in response to methotrexate in the breast tumour cell","volume":"68","author":"Hattangadi","year":"2004","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.jhep.2008.10.026_bib38","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1084\/jem.188.11.2033","article-title":"p53 activates the CD95 (APO-1\/Fas) gene in response to DNA damage by anticancer drugs","volume":"188","author":"Muller","year":"1998","journal-title":"J Exp Med"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016882780800799X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016882780800799X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T04:10:47Z","timestamp":1589429447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016882780800799X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S016882780800799X"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2008.10.026","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}