{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:11:45Z","timestamp":1793059905595,"version":"4.5.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.jhep.2013.03.035","type":"journal-article","created":{"date-parts":[[2013,4,8]],"date-time":"2013-04-08T19:16:17Z","timestamp":1365448577000},"page":"351-357","source":"Crossref","is-referenced-by-count":162,"title":["Sleep duration and quality in relation to non-alcoholic fatty liver disease in middle-aged workers and their spouses"],"prefix":"10.1016","volume":"59","author":[{"given":"Chan-Won","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung Eun","family":"Yun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Suk","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoosoo","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Suk","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Jung","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Hyun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eui Jeong","family":"Woo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan Hee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hocheol","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seungho","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2013.03.035_b0005","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1365-2869.2008.00627.x","article-title":"Trends in self-reported sleep duration and insomnia-related symptoms in Finland from 1972 to 2005: a comparative review and re-analysis of Finnish population samples","volume":"17","author":"Kronholm","year":"2008","journal-title":"J Sleep Res"},{"key":"10.1016\/j.jhep.2013.03.035_b0010","unstructured":"National Sleep Foundation. Summary of findings: 2008 sleep in America poll. [cited 2012 11 July]; available from: http:\/\/www.sleepfoundation.org\/sites\/default\/files\/2008%20POLL%20SOF.PDF."},{"key":"10.1016\/j.jhep.2013.03.035_b0015","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.beem.2010.07.001","article-title":"Sleep duration and cardiometabolic risk: a review of the epidemiologic evidence","volume":"24","author":"Knutson","year":"2010","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.jhep.2013.03.035_b0020","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/j.1365-2869.2008.00732.x","article-title":"Sleep duration and mortality: a systematic review and meta-analysis","volume":"18","author":"Gallicchio","year":"2009","journal-title":"J Sleep Res"},{"key":"10.1016\/j.jhep.2013.03.035_b0025","doi-asserted-by":"crossref","first-page":"414","DOI":"10.2337\/dc09-1124","article-title":"Quantity and quality of sleep and incidence of type 2 diabetes: a systematic review and meta-analysis","volume":"33","author":"Cappuccio","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jhep.2013.03.035_b0030","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.5665\/sleep.1382","article-title":"Sleep duration and sleep quality in relation to 12-year cardiovascular disease incidence: the MORGEN study","volume":"34","author":"Hoevenaar-Blom","year":"2011","journal-title":"Sleep"},{"key":"10.1016\/j.jhep.2013.03.035_b0035","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1365-2869.2011.00990.x","article-title":"Sleep disturbance is associated with cardiovascular and metabolic disorders","volume":"21","author":"Grandner","year":"2012","journal-title":"J Sleep Res"},{"key":"10.1016\/j.jhep.2013.03.035_b0040","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.jacc.2003.07.050","article-title":"Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk","volume":"43","author":"Meier-Ewert","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jhep.2013.03.035_b0045","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1055\/s-0028-1091978","article-title":"The epidemiology of nonalcoholic fatty liver disease: a global perspective","volume":"28","author":"Lazo","year":"2008","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.jhep.2013.03.035_b0050","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jhep.2004.09.012","article-title":"The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies","volume":"42","author":"Adams","year":"2005","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2013.03.035_b0055","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.jhep.2004.02.013","article-title":"The spectrum expanded: cryptogenic cirrhosis and the natural history of non-alcoholic fatty liver disease","volume":"40","author":"Caldwell","year":"2004","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2013.03.035_b0060","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1016\/j.jhep.2011.10.027","article-title":"Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace","volume":"56","author":"Baffy","year":"2012","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2013.03.035_b0065","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/ajg.2009.67","article-title":"NAFLD as a risk factor for the development of diabetes and the metabolic syndrome: an eleven-year follow-up study","volume":"104","author":"Adams","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jhep.2013.03.035_b0070","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1056\/NEJMra0912063","article-title":"Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease","volume":"363","author":"Targher","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jhep.2013.03.035_b0075","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.jhep.2010.04.030","article-title":"Prevalence of non-alcoholic fatty liver disease and its association with cardiovascular disease in patients with type 1 diabetes","volume":"53","author":"Targher","year":"2010","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2013.03.035_b0080","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1093\/eurheartj\/ehr453","article-title":"Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor?","volume":"33","author":"Bhatia","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jhep.2013.03.035_b0085","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.jhep.2011.12.011","article-title":"Predictors for incidence and remission of NAFLD in the general population during a seven-year prospective follow-up","volume":"56","author":"Zelber-Sagi","year":"2012","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2013.03.035_b0090","doi-asserted-by":"crossref","first-page":"16381","DOI":"10.1073\/pnas.1113359108","article-title":"Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease","volume":"108","author":"Kumashiro","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jhep.2013.03.035_b0095","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1053\/jhep.2003.50193","article-title":"Nonalcoholic steatohepatitis: summary of an AASLD single topic conference","volume":"37","author":"Neuschwander-Tetri","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2013.03.035_b0100","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.jhep.2013.03.035_b0105","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.diabres.2006.04.013","article-title":"Appropriate waist circumference cutoff points for central obesity in Korean adults","volume":"75","author":"Lee","year":"2007","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.jhep.2013.03.035_b0110","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1017\/S1368980008002802","article-title":"Are Asians at greater mortality risks for being overweight than Caucasians? Redefining obesity for Asians","volume":"12","author":"Wen","year":"2009","journal-title":"Public Health Nutr"},{"key":"10.1016\/j.jhep.2013.03.035_b0115","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.2337\/dc12-0515","article-title":"Fatty liver, insulin resistance, and features of metabolic syndrome: relationships with coronary artery calcium in 10,153 people","volume":"35","author":"Sung","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jhep.2013.03.035_b0120","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/S1590-8658(02)80111-6","article-title":"Increased liver echogenicity at ultrasound examination reflects degree of steatosis but not of fibrosis in asymptomatic patients with mild\/moderate abnormalities of liver transaminases","volume":"34","author":"Mathiesen","year":"2002","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.jhep.2013.03.035_b0125","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1471-230X-6-33","article-title":"The fatty liver index: a simple and accurate predictor of hepatic steatosis in the general population","volume":"6","author":"Bedogni","year":"2006","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.jhep.2013.03.035_b0130","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.2169\/internalmedicine.50.5844","article-title":"Association of short sleep duration with obesity, diabetes, fatty liver and behavioral factors in Japanese men","volume":"50","author":"Hsieh","year":"2011","journal-title":"Intern Med"},{"key":"10.1016\/j.jhep.2013.03.035_b0135","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/sleep\/28.10.1289","article-title":"Inadequate sleep as a risk factor for obesity: analyses of the NHANES I","volume":"28","author":"Gangwisch","year":"2005","journal-title":"Sleep"},{"key":"10.1016\/j.jhep.2013.03.035_b0140","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1093\/aje\/kwj280","article-title":"Association between reduced sleep and weight gain in women","volume":"164","author":"Patel","year":"2006","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jhep.2013.03.035_b0145","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/j.1440-1746.2010.06253.x","article-title":"A fresh look at NASH pathogenesis. Part 1: the metabolic movers","volume":"25","author":"Larter","year":"2010","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2013.03.035_b0150","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1136\/gut.2008.161885","article-title":"Weight gain within the normal weight range predicts ultrasonographically detected fatty liver in healthy Korean men","volume":"58","author":"Chang","year":"2009","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2013.03.035_b0155","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1056\/NEJMoa1014296","article-title":"Changes in diet and lifestyle and long-term weight gain in women and men","volume":"364","author":"Mozaffarian","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jhep.2013.03.035_b0160","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1210\/jc.2010-1978","article-title":"Twenty-four-hour profiles of acylated and total ghrelin: relationship with glucose levels and impact of time of day and sleep","volume":"96","author":"Spiegel","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jhep.2013.03.035_b0165","doi-asserted-by":"crossref","first-page":"5762","DOI":"10.1210\/jc.2004-1003","article-title":"Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin","volume":"89","author":"Spiegel","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jhep.2013.03.035_b0170","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1161\/HYPERTENSIONAHA.107.095471","article-title":"Gender-specific associations of short sleep duration with prevalent and incident hypertension: the Whitehall II Study","volume":"50","author":"Cappuccio","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.jhep.2013.03.035_b0175","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1097\/HJH.0b013e328335d076","article-title":"A population-based study of reduced sleep duration and hypertension: the strongest association may be in premenopausal women","volume":"28","author":"Stranges","year":"2010","journal-title":"J Hypertens"},{"key":"10.1016\/j.jhep.2013.03.035_b0180","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.sleep.2011.04.006","article-title":"Short sleep duration is associated with insulin resistance independent of adiposity in Chinese adult twins","volume":"12","author":"Liu","year":"2011","journal-title":"Sleep Med"},{"key":"10.1016\/j.jhep.2013.03.035_b0185","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.bbi.2008.01.011","article-title":"Self-reported symptoms of sleep disturbance and inflammation, coagulation, insulin resistance and psychosocial distress: evidence for gender disparity","volume":"22","author":"Suarez","year":"2008","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.jhep.2013.03.035_b0190","doi-asserted-by":"crossref","first-page":"e354","DOI":"10.1111\/j.1464-5491.2012.03711.x","article-title":"Sleep duration and sleep quality are associated differently with alterations of glucose homeostasis","volume":"29","author":"Byberg","year":"2012","journal-title":"Diabet Med"},{"key":"10.1016\/j.jhep.2013.03.035_b0195","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1111\/j.1464-5491.2011.03459.x","article-title":"Sleep disturbances and insulin resistance","volume":"28","author":"Van Cauter","year":"2011","journal-title":"Diabet Med"},{"key":"10.1016\/j.jhep.2013.03.035_b0200","doi-asserted-by":"crossref","first-page":"783","DOI":"10.5665\/sleep.1874","article-title":"Sleep is associated with the metabolic syndrome in a multi-ethnic cohort of midlife women: the SWAN Sleep Study","volume":"35","author":"Hall","year":"2012","journal-title":"Sleep"},{"key":"10.1016\/j.jhep.2013.03.035_b0205","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.annepidem.2010.05.002","article-title":"Short sleep duration is associated with the development of impaired fasting glucose: the Western New York Health Study","volume":"20","author":"Rafalson","year":"2010","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.jhep.2013.03.035_b0210","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2337\/dc11-1455","article-title":"Short sleep duration and poor sleep quality increase the risk of diabetes in Japanese workers with no family history of diabetes","volume":"35","author":"Kita","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jhep.2013.03.035_b0215","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1365-2036.2007.03586.x","article-title":"Adipokines and cytokines in non-alcoholic fatty liver disease","volume":"27","author":"Jarrar","year":"2008","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.jhep.2013.03.035_b0220","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1111\/j.1572-0241.2007.01774.x","article-title":"Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis","volume":"103","author":"Wieckowska","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jhep.2013.03.035_b0225","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.biopsycho.2009.04.008","article-title":"Normative variation in self-reported sleep quality and sleep debt is associated with stimulated pro-inflammatory cytokine production","volume":"82","author":"Prather","year":"2009","journal-title":"Biol Psychol"},{"key":"10.1016\/j.jhep.2013.03.035_b0230","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.tem.2006.08.003","article-title":"Importance of TNFalpha and neutral lipases in human adipose tissue lipolysis","volume":"17","author":"Langin","year":"2006","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.jhep.2013.03.035_b0235","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1210\/jcem.86.8.7778","article-title":"Chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis: clinical implications","volume":"86","author":"Vgontzas","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jhep.2013.03.035_b0240","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1365-2265.2006.02466.x","article-title":"Associations between liver histology and cortisol secretion in subjects with nonalcoholic fatty liver disease","volume":"64","author":"Targher","year":"2006","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.jhep.2013.03.035_b0245","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1046\/j.1365-2869.1999.00155.x","article-title":"Comparison between subjective and actigraphic measurement of sleep and sleep rhythms","volume":"8","author":"Lockley","year":"1999","journal-title":"J Sleep Res"},{"key":"10.1016\/j.jhep.2013.03.035_b0250","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1097\/01.GME.0000097741.18446.3E","article-title":"Self-reported sleep in postmenopausal women","volume":"11","author":"Regestein","year":"2004","journal-title":"Menopause"},{"key":"10.1016\/j.jhep.2013.03.035_b0255","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jhep.2011.04.022","article-title":"Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese","volume":"56","author":"Aron-Wisnewsky","year":"2012","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2013.03.035_b0260","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1164\/ajrccm.149.3.8118642","article-title":"Gender differences in sleep disordered breathing in a community-based sample","volume":"149","author":"Redline","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jhep.2013.03.035_b0265","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s11325-011-0523-z","article-title":"Age- and gender-related characteristics of obstructive sleep apnea","volume":"16","author":"Gabbay","year":"2012","journal-title":"Sleep Breath"},{"key":"10.1016\/j.jhep.2013.03.035_b0270","first-page":"539","article-title":"Diagnosis of fatty liver disease: is biopsy necessary?","volume":"15","author":"Joy","year":"2003","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2013.03.035_b0275","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1053\/gast.2002.36572","article-title":"AGA technical review on nonalcoholic fatty liver disease","volume":"123","author":"Sanyal","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2013.03.035_b0280","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1053\/gast.2003.50032","article-title":"Defining nonalcoholic fatty liver disease: implications for epidemiologic studies","volume":"124","author":"Clark","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2013.03.035_b0285","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0168-8278(01)00151-9","article-title":"The spectrum of liver disease in the general population: lesson from the Dionysos study","volume":"35","author":"Bellentani","year":"2001","journal-title":"J Hepatol"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827813002183?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827813002183?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,16]],"date-time":"2018-10-16T23:04:29Z","timestamp":1539731069000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827813002183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":57,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S0168827813002183"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2013.03.035","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]}}}