{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T17:22:10Z","timestamp":1785864130509,"version":"3.56.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T00:00:00Z","timestamp":1488844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journal-of-hepatology.eu","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.jhep.2017.03.001","type":"journal-article","created":{"date-parts":[[2017,3,9]],"date-time":"2017-03-09T02:21:17Z","timestamp":1489026077000},"page":"47-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":122,"title":["Infusion of mesenchymal stromal cells after deceased liver transplantation: A phase I\u2013II, open-label, clinical study"],"prefix":"10.1016","volume":"67","author":[{"given":"Olivier","family":"Detry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan","family":"Vandermeulen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-H\u00e9l\u00e8ne","family":"Delbouille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Somja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noella","family":"Bletard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Briquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Lechanteur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Giet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Baudoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel","family":"Hannon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Baron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Beguin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2017.03.001_b0005","doi-asserted-by":"crossref","first-page":"S170","DOI":"10.1016\/j.jhep.2015.02.042","article-title":"From immunosuppression to tolerance","volume":"62","author":"Adams","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2017.03.001_b0010","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement","volume":"8","author":"Dominici","year":"2006","journal-title":"Cytotherapy"},{"key":"10.1016\/j.jhep.2017.03.001_b0015","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1432-2277.2008.00786.x","article-title":"Potential of mesenchymal stem cells as immune therapy in solid organ transplantation","volume":"22","author":"Crop","year":"2009","journal-title":"Transpl Int"},{"key":"10.1016\/j.jhep.2017.03.001_b0020","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1093\/ndt\/gft538","article-title":"Mesenchymal stromal cell therapy in conditions of renal ischaemia\/reperfusion","volume":"29","author":"Erpicum","year":"2014","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.jhep.2017.03.001_b0025","doi-asserted-by":"crossref","first-page":"602597","DOI":"10.1155\/2015\/602597","article-title":"Mesenchymal Stromal Cell Therapy in Ischaemia\/Reperfusion Injury","volume":"2015","author":"Rowart","year":"2015","journal-title":"J Immunol Res"},{"key":"10.1016\/j.jhep.2017.03.001_b0030","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/MOT.0b013e32835c5016","article-title":"Mesenchymal stromal cells to promote solid organ transplantation tolerance","volume":"18","author":"Casiraghi","year":"2013","journal-title":"Curr Opin Organ Transplant"},{"key":"10.1016\/j.jhep.2017.03.001_b0035","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/TP.0b013e318298f9fa","article-title":"Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials","volume":"96","author":"Franquesa","year":"2013","journal-title":"Transplantation"},{"key":"10.1016\/j.jhep.2017.03.001_b0040","doi-asserted-by":"crossref","first-page":"a015560","DOI":"10.1101\/cshperspect.a015560","article-title":"Mesenchymal stromal cells in transplantation rejection and tolerance","volume":"3","author":"English","year":"2013","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10.1016\/j.jhep.2017.03.001_b0045","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1001\/jama.2012.316","article-title":"Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial","volume":"307","author":"Tan","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jhep.2017.03.001_b0050","doi-asserted-by":"crossref","first-page":"16418","DOI":"10.3748\/wjg.v20.i44.16418","article-title":"Rationale for the potential use of mesenchymal stromal cells in liver transplantation","volume":"20","author":"Vandermeulen","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jhep.2017.03.001_b0055","doi-asserted-by":"crossref","first-page":"e47559","DOI":"10.1371\/journal.pone.0047559","article-title":"Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials","volume":"7","author":"Lalu","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jhep.2017.03.001_b0060","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.mvr.2009.02.001","article-title":"Is the intravascular administration of mesenchymal stem cells safe? Mesenchymal stem cells and intravital microscopy","volume":"77","author":"Furlani","year":"2009","journal-title":"Microvasc Res"},{"key":"10.1016\/j.jhep.2017.03.001_b0065","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1186\/1745-6215-13-211","article-title":"Treatment-emergent adverse events after infusion of adherent stem cells: the MiSOT-I score for solid organ transplantation","volume":"13","author":"Dillmann","year":"2012","journal-title":"Trials"},{"key":"10.1016\/j.jhep.2017.03.001_b0070","doi-asserted-by":"crossref","first-page":"412","DOI":"10.2215\/CJN.04950610","article-title":"Autologous mesenchymal stromal cells and kidney transplantation: a pilot study of safety and clinical feasibility","volume":"6","author":"Perico","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.jhep.2017.03.001_b0075","doi-asserted-by":"crossref","first-page":"107","DOI":"10.5966\/sctm.2012-0114","article-title":"Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I study","volume":"2","author":"Reinders","year":"2013","journal-title":"Stem Cells Trans Med"},{"key":"10.1016\/j.jhep.2017.03.001_b0080","doi-asserted-by":"crossref","first-page":"e6657","DOI":"10.1371\/journal.pone.0006657","article-title":"Fibrogenic potential of human multipotent mesenchymal stromal celles in injured liver","volume":"4","author":"Baerschiger","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jhep.2017.03.001_b0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/tri.12415","article-title":"Caveats of mesenchymal stem cell therapy in solid organ transplantation","volume":"28","author":"Haarer","year":"2015","journal-title":"Transpl Int"},{"key":"10.1016\/j.jhep.2017.03.001_b0090","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.jcyt.2013.03.005","article-title":"Risk of tumorigenicity in mesenchymal stromal cell-based therapies\u2013bridging scientific observations and regulatory viewpoints","volume":"15","author":"Barkholt","year":"2013","journal-title":"Cytotherapy"},{"key":"10.1016\/j.jhep.2017.03.001_b0095","doi-asserted-by":"crossref","first-page":"2789","DOI":"10.1111\/j.1600-6143.2012.04195.x","article-title":"The Eurotransplant donor risk index in liver transplantation: ET-DRI","volume":"12","author":"Braat","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1016\/j.jhep.2017.03.001_b0100","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/bjs.9488","article-title":"Donor age as a risk factor in donation after circulatory death liver transplantation in a controlled withdrawal protocol programme","volume":"101","author":"Detry","year":"2014","journal-title":"Br J Surg"},{"key":"10.1016\/j.jhep.2017.03.001_b0105","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0002-9610(99)80151-2","article-title":"Temporary portocaval anastomosis with preservation of caval flow during orthotopic liver transplantation","volume":"169","author":"Belghiti","year":"1995","journal-title":"Am J Surg"},{"key":"10.1016\/j.jhep.2017.03.001_b0110","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s12967-016-0892-y","article-title":"Clinical-scale expansion of mesenchymal stromal cells: a large banking experience","volume":"14","author":"Lechanteur","year":"2016","journal-title":"J Transl Med"},{"key":"10.1016\/j.jhep.2017.03.001_b0115","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.bbmt.2010.01.011","article-title":"Cotransplantation of mesenchymal stem cells might prevent death from graft-vs.-host disease (GVHD) without abrogating graft-vs.-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning","volume":"16","author":"Baron","year":"2010","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.jhep.2017.03.001_b0120","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1002\/hep.510250328","article-title":"An international consensus document","volume":"25","author":"Banff schema for grading liver allograft rejection","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2017.03.001_b0125","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.1158\/1078-0432.CCR-14-3374","article-title":"Immune Recovery after Allogeneic Hematopoietic Stem Cell Transplantation Following Flu-TBI vs. TLI-ATG Conditioning","volume":"21","author":"Hannon","year":"2015","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.jhep.2017.03.001_b0130","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1038\/leu.2014.127","article-title":"Mesenchymal stromal cells in the antimicrobial host response of hematopoietic stem cell recipients with graft-vs.-host disease\u2013friends or foes?","volume":"28","author":"Balan","year":"2014","journal-title":"Leukemia"},{"key":"10.1016\/j.jhep.2017.03.001_b0135","doi-asserted-by":"crossref","first-page":"43255","DOI":"10.18632\/oncotarget.6486","article-title":"Validation of a multicolor staining to monitor phosphoSTAT5 levels in regulatory T cell subsets","volume":"6","author":"Ehx","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.jhep.2017.03.001_b0140","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/TP.0000000000000068","article-title":"Impact of cotransplantation of mesenchymal stem cells on lung function after unrelated allogeneic hematopoietic stem cell transplantation following non-myeloablative conditioning","volume":"98","author":"Moermans","year":"2014","journal-title":"Transplantation"},{"key":"10.1016\/j.jhep.2017.03.001_b0145","doi-asserted-by":"crossref","first-page":"148","DOI":"10.3389\/fimmu.2014.00148","article-title":"The life and fate of mesenchymal stem cells","volume":"5","author":"Eggenhofer","year":"2014","journal-title":"Front Immunol"},{"key":"10.1016\/j.jhep.2017.03.001_b0150","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.4049\/jimmunol.181.6.3933","article-title":"Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells","volume":"181","author":"Casiraghi","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.jhep.2017.03.001_b0155","doi-asserted-by":"crossref","first-page":"3347","DOI":"10.1016\/j.transproceed.2009.08.030","article-title":"Human mesenchymal stem cells and immunosuppressive drug interactions in allogeneic responses: an in vitro study using human cells","volume":"41","author":"Buron","year":"2009","journal-title":"Transplant Proc"},{"key":"10.1016\/j.jhep.2017.03.001_b0160","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1097\/TP.0b013e31818aa536","article-title":"Susceptibility of human mesenchymal stem cells to tacrolimus, mycophenolic acid, and rapamycin","volume":"86","author":"Hoogduijn","year":"2008","journal-title":"Transplantation"},{"key":"10.1016\/j.jhep.2017.03.001_b0165","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.trim.2008.08.004","article-title":"Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate","volume":"20","author":"Popp","year":"2008","journal-title":"Transpl Immunol"},{"key":"10.1016\/j.jhep.2017.03.001_b0170","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1111\/ajt.12934","article-title":"Superiority of rapamycin over tacrolimus in preserving nonhuman primate Treg half-life and phenotype after adoptive transfer","volume":"14","author":"Singh","year":"2014","journal-title":"Am J Transplant"},{"key":"10.1016\/j.jhep.2017.03.001_b0175","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1111\/ajt.13617","article-title":"Hepatic Infiltrates in Operational Tolerant Patients After Liver Transplantation Show Enrichment of Regulatory T Cells Before Proinflammatory Genes Are Downregulated","volume":"16","author":"Taubert","year":"2016","journal-title":"Am J Transplant"},{"key":"10.1016\/j.jhep.2017.03.001_b0180","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1002\/hep.28459","article-title":"A Pilot Study of Operational Tolerance with a Regulatory T Cell-Based Cell Therapy in Living Donor Liver Transplantation","volume":"64","author":"Todo","year":"2016","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2017.03.001_b0185","doi-asserted-by":"crossref","first-page":"214","DOI":"10.3109\/08820139.2011.619022","article-title":"Mesenchymal stem cell-mediated immature dendritic cells induce regulatory T cell-based immunosuppressive effect","volume":"41","author":"Choi","year":"2012","journal-title":"Immunol Invest"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827817301319?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827817301319?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T03:15:16Z","timestamp":1536290116000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827817301319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["S0168827817301319"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2017.03.001","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Infusion of mesenchymal stromal cells after deceased liver transplantation: A phase I\u2013II, open-label, clinical study","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2017.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 European Association for the Study of the Liver. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}