{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T21:39:53Z","timestamp":1789421993650,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journal-of-hepatology.eu","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.jhep.2017.06.010","type":"journal-article","created":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T16:31:42Z","timestamp":1498062702000},"page":"940-949","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":104,"title":["Alfapump\u00ae system vs. large volume paracentesis for refractory ascites: A multicenter randomized controlled study"],"prefix":"10.1016","volume":"67","author":[{"given":"Christophe","family":"Bureau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Adebayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mael","family":"Chalret de Rieu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Elkrief","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Valla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Peck-Radosavljevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"McCune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Vargas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Macarena","family":"Simon-Talero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Cordoba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Angeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Rosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stewart","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Malago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Stepanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zobair M.","family":"Younossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Trepte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleg","family":"Borisenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Inhaber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Jalan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2017.06.010_b0005","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.cgh.2006.08.007","article-title":"Natural history of patients hospitalized for management of cirrhotic ascites","volume":"4","author":"Planas","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2017.06.010_b0010","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1002\/hep.22853","article-title":"Management of adult patients with ascites due to cirrhosis: an update","volume":"49","author":"Runyon","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2017.06.010_b0015","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/0016-5085(92)90203-B","article-title":"Arteriolar vasodilation and the pathogenesis of the hyperdynamic circulation and renal sodium and water retention in cirrhosis","volume":"102","author":"Arroyo","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2017.06.010_b0020","doi-asserted-by":"crossref","first-page":"vi1","DOI":"10.1136\/gut.2006.099580","article-title":"Guidelines on the management of ascites in cirrhosis","volume":"55","author":"Moore","year":"2006","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2017.06.010_b0025","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jhep.2010.05.004","article-title":"EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis","volume":"53","year":"2010","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2017.06.010_b0030","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/0016-5085(88)90691-9","article-title":"Randomized comparative study of therapeutic paracentesis with and without intravenous albumin in cirrhosis","volume":"94","author":"Gines","year":"1988","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2017.06.010_b0035","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.amjmed.2012.09.016","article-title":"Clinical outcomes after bedside and interventional radiology paracentesis procedures","volume":"126","author":"Barsuk","year":"2013","journal-title":"Am J Med"},{"key":"10.1016\/j.jhep.2017.06.010_b0040","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1002\/jhm.2153","article-title":"Specialties performing paracentesis procedures at university hospitals: implications for training and certification","volume":"9","author":"Barsuk","year":"2014","journal-title":"J Hosp Med"},{"key":"10.1016\/j.jhep.2017.06.010_b0045","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1053\/gast.2002.37073","article-title":"Transjugular intrahepatic portosystemic shunting vs. paracentesis plus albumin for refractory ascites in cirrhosis","volume":"123","author":"Gines","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2017.06.010_b0050","unstructured":"American College of Radiology, Society for Pediatric Radiology, and Society for Interventional Radiology, ACR-SIR-SPR practice parameter for the creation of a transjugular intrahepatic portosystemic shunt (TIPS), Amended 2014 (Resolution 39). Practice Parameters and Technical Standards, 2014: p. 1-22."},{"key":"10.1016\/j.jhep.2017.06.010_b0055","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1002\/hep.1840400409","article-title":"Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death","volume":"40","author":"Heuman","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2017.06.010_b0060","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/j.jhep.2012.12.020","article-title":"Automated low flow pump system for the treatment of refractory ascites: a multi-center safety and efficacy study","volume":"58","author":"Bellot","year":"2013","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2017.06.010_b0065","doi-asserted-by":"crossref","first-page":"650","DOI":"10.2471\/BLT.08.050955","article-title":"The Declaration of Helsinki and public health","volume":"86","author":"Williams","year":"2008","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.jhep.2017.06.010_b0070","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.jhep.2014.12.029","article-title":"Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites","volume":"62","author":"Angeli","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.jhep.2017.06.010_b0075","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1186\/cc5713","article-title":"Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury","volume":"11","author":"Mehta","year":"2007","journal-title":"Crit Care"},{"key":"10.1016\/j.jhep.2017.06.010_b0080","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1002\/hep.24786","article-title":"Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials","volume":"55","author":"Bernardi","year":"2012","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2017.06.010_b0085","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1002\/hep.21358","article-title":"Derivation and validation of a new global method for assessing nutritional status in patients with cirrhosis","volume":"44","author":"Morgan","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2017.06.010_b0090","series-title":"Medical statistics: a textbook for the health sciences","author":"Campbell","year":"2010"},{"key":"10.1016\/j.jhep.2017.06.010_b0095","series-title":"Economic evaluation in clinical trials","author":"Glick","year":"2014"},{"key":"10.1016\/j.jhep.2017.06.010_b0100","series-title":"British National Formulary (BNF) 70","author":"Joint Formulary Committee","year":"2015"},{"key":"10.1016\/j.jhep.2017.06.010_b0105","unstructured":"Department of Health UK. Drugs and pharmaceutical electronic market information (eMit). 2016 [cited 2016 February 30]; Available from: https:\/\/www.gov.uk\/government\/publications\/drugs-and-pharmaceutical-electronic-market-information-emit."},{"key":"10.1016\/j.jhep.2017.06.010_b0110","unstructured":"NHS Business Services Authority and NHS Prescription Services, National Health Service Drug Tariff for England and Wales, D.o. Health, Editor. 2016, Department of Health: London."},{"key":"10.1016\/j.jhep.2017.06.010_b0115","unstructured":"Personal Social Services Research Unit. Unit Costs of Health and Social Care 2014. 2014 2014 [cited 2016 February 2]; Available from:http:\/\/www.pssru.ac.uk\/project-pages\/unit-costs\/2014\/."},{"key":"10.1016\/j.jhep.2017.06.010_b0120","unstructured":"Department of Health. National Schedule of Reference Costs Year: 2014 \u2013 2015. 2016 2016 [cited 2017 February 2]; Available from: https:\/\/www.gov.uk\/government\/publications\/nhs-reference-costs-2014-to-2015."},{"key":"10.1016\/j.jhep.2017.06.010_b0125","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1136\/gut.45.2.295","article-title":"Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease","volume":"45","author":"Younossi","year":"1999","journal-title":"Gut"},{"key":"10.1016\/j.jhep.2017.06.010_b0130","unstructured":"Canadian Agency for Drugs and Technologies in Health. APPENDIX 5 VALIDITY OF OUTCOME MEASURES; Sofosbuvir (Sovaldi): Sofosbuvir is Indicated for the Treatment of Chronic Hepatitis C Virus (CHC) Infection in Adult Patients With Compensated Liver Disease, Including Cirrhosis 2014 [cited 2016 2 Dec]; Available from: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK253697\/."},{"key":"10.1016\/j.jhep.2017.06.010_b0135","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/lt.24763","article-title":"Effects of alfapump system on kidney and circulatory function in patients with cirrhosis and refractory ascites","volume":"23","author":"Sola","year":"2017","journal-title":"Liver Transpl"},{"key":"10.1016\/j.jhep.2017.06.010_b0140","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/0016-5085(91)80019-6","article-title":"Ascites increases the resting energy expenditure in liver cirrhosis","volume":"100","author":"Dolz","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2017.06.010_b0145","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/j.1478-3231.2011.02498.x","article-title":"Changes in body composition after transjugular intrahepatic portosystemic stent in cirrhosis: a critical review of literature","volume":"31","author":"Dasarathy","year":"2011","journal-title":"Liver Int"},{"key":"10.1016\/j.jhep.2017.06.010_b0150","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.jhep.2003.10.011","article-title":"Weight gain after transjugular intrahepatic portosystemic shunt is associated with improvement in body composition in malnourished patients with cirrhosis and hypermetabolism","volume":"40","author":"Plauth","year":"2004","journal-title":"J Hepatol"}],"updated-by":[{"DOI":"10.1016\/j.jhep.2017.12.017","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000}},{"DOI":"10.1016\/j.jhep.2019.11.023","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000}}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827817320809?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827817320809?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T14:57:08Z","timestamp":1535727428000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827817320809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S0168827817320809"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2017.06.010","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.jhep.2019.11.023","asserted-by":"object"},{"id-type":"doi","id":"10.1016\/j.jhep.2017.12.017","asserted-by":"object"}]},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alfapump\u00ae system vs. large volume paracentesis for refractory ascites: A multicenter randomized controlled study","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2017.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}