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The immunological basis for immunization series. In. Immunization vaccines and biologicals. 2010 ed: World Health Organization; 2010:39."},{"key":"10.1016\/j.jhep.2017.08.034_b0380","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/1476-072X-10-57","article-title":"Challenges to mapping the health risk of hepatitis A virus infection","volume":"10","author":"Mohd Hanafiah","year":"2011","journal-title":"Int J Health Geogr"},{"key":"10.1016\/j.jhep.2017.08.034_b0385","doi-asserted-by":"crossref","first-page":"6653","DOI":"10.1016\/j.vaccine.2010.08.037","article-title":"Hepatitis A virus seroprevalence by age and world region, 1990 and 2005","volume":"28","author":"Jacobsen","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.jhep.2017.08.034_b0390","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0140-6736(14)61682-2","article-title":"Causes of Death C. 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