{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:00:30Z","timestamp":1792036830458,"version":"4.4.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.jhep.2020.09.034","type":"journal-article","created":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T12:34:24Z","timestamp":1602160464000},"page":"584-592","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":80,"title":["Baveno VI criteria and spleen stiffness measurement rule out high-risk varices in virally suppressed HBV-related cirrhosis"],"prefix":"10.1016","volume":"74","author":[{"given":"Haiyu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biao","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianyi","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaoping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqun","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuyuan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yabing","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yixiu","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qintao","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinjun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4275-9149","authenticated-orcid":false,"given":"Jinjun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlin","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2020.09.034_bib1","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.jhep.2015.05.022","article-title":"Expanding consensus in portal hypertension: report of the Baveno VI consensus workshop: stratifying risk and individualizing care for portal hypertension","volume":"63","author":"de Franchis","year":"2015","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib2","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.jhep.2010.06.004","article-title":"Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension","volume":"53","author":"de Franchis","year":"2010","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib3","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1002\/hep.28824","article-title":"Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: the \u201cAnticipate\u201d study","volume":"64","author":"Abraldes","year":"2016","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2020.09.034_bib4","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.jhep.2016.06.021","article-title":"Validation of the Baveno VI criteria to identify low risk cirrhotic patients not requiring endoscopic surveillance for varices","volume":"65","author":"Maurice","year":"2016","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib5","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1111\/liv.13379","article-title":"Validating, deconstructing and refining Baveno criteria for ruling out high-risk varices in patients with compensated cirrhosis","volume":"37","author":"Jangouk","year":"2017","journal-title":"Liver Int"},{"key":"10.1016\/j.jhep.2020.09.034_bib6","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1111\/jgh.13781","article-title":"Validation of noninvasive methods to predict the presence of gastroesophageal varices in a cohort of patients with compensated advanced chronic liver disease","volume":"32","author":"Llop","year":"2017","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib7","first-page":"825","article-title":"Consensus statements on the prevention and management of hepatitis B and hepatitis C in the Asia\u2013Pacific region","volume":"15","author":"Chen","year":"2001","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib8","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1002\/hep.29800","article-title":"Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance","volume":"67","author":"Terrault","year":"2018","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2020.09.034_bib9","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jhep.2018.03.024","article-title":"EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis","volume":"69","author":"Angeli","year":"2018","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib10","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.jhep.2017.03.021","article-title":"EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection","volume":"67","author":"Lampertico","year":"2017","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib11","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/hep.27950","article-title":"Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus","volume":"62","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2020.09.034_bib12","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.jhep.2012.07.037","article-title":"Hepatitis C infection, antiviral treatment and mental health: a European expert consensus statement","volume":"57","author":"Schaefer","year":"2012","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib13","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/jvh.12814","article-title":"Interpretation of liver stiffness measurement-based approach for the monitoring of hepatitis B patients with antiviral therapy: a 2-year prospective study","volume":"25","author":"Liang","year":"2018","journal-title":"J\u00a0Viral Hepat"},{"key":"10.1016\/j.jhep.2020.09.034_bib14","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1111\/liv.13623","article-title":"On-treatment changes of liver stiffness at week 26 could predict 2-year clinical outcomes in HBV-related compensated cirrhosis","volume":"38","author":"Wu","year":"2018","journal-title":"Liver Int"},{"key":"10.1016\/j.jhep.2020.09.034_bib15","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cgh.2017.04.038","article-title":"Magnitude and kinetics of decrease in liver stiffness after antiviral therapy in patients with chronic hepatitis C: a systematic review and meta-analysis","volume":"16","author":"Singh","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib16","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1053\/j.gastro.2018.11.053","article-title":"Validation of Baveno VI criteria for screening and surveillance of esophageal varices in patients with compensated cirrhosis and a sustained response to antiviral therapy","volume":"156","author":"Thabut","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jhep.2020.09.034_bib17","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1111\/liv.13560","article-title":"A\u00a0new screening strategy for varices by liver and spleen stiffness measurement (LSSM) in cirrhotic patients: a randomized trial","volume":"38","author":"Wong","year":"2018","journal-title":"Liver Int"},{"key":"10.1016\/j.jhep.2020.09.034_bib18","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1002\/hep.30522","article-title":"Low risk of variceal bleeding in patients with cirrhosis after variceal screening stratified by liver\/spleen stiffness","volume":"70","author":"Wong","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.jhep.2020.09.034_bib19","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jhep.2018.04.023","article-title":"A\u00a0combined model based on spleen stiffness measurement and Baveno VI criteria to rule out high-risk varices in advanced chronic liver disease","volume":"69","author":"Colecchia","year":"2018","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib20","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s12072-014-9580-2","article-title":"Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014","volume":"8","author":"Sarin","year":"2014","journal-title":"Hepatol Int"},{"key":"10.1016\/j.jhep.2020.09.034_bib21","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1016\/S0140-6736(14)60121-5","article-title":"Liver cirrhosis","volume":"383","author":"Tsochatzis","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.jhep.2020.09.034_bib22","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.dld.2011.08.004","article-title":"Improving transient elastography performance for detecting hepatitis B cirrhosis","volume":"44","author":"Chen","year":"2012","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.jhep.2020.09.034_bib23","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/j.1440-1746.2011.06889.x","article-title":"Is transient elastography valuable for high-risk esophageal varices prediction in patients with hepatitis-B-related cirrhosis?","volume":"27","author":"Chen","year":"2012","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib24","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1111\/liv.14108","article-title":"Impacts of cigarette smoking on liver fibrosis and its regression under therapy in male patients with chronic hepatitis B","volume":"39","author":"Xiong","year":"2019","journal-title":"Liver Int"},{"key":"10.1016\/j.jhep.2020.09.034_bib25","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1097\/MEG.0000000000000393","article-title":"Liver and spleen stiffness and other noninvasive methods to assess portal hypertension in cirrhotic patients: a review of the literature","volume":"27","author":"Colecchia","year":"2015","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib26","doi-asserted-by":"crossref","first-page":"13293","DOI":"10.3748\/wjg.v20.i37.13293","article-title":"Update on hepatitis B virus infection","volume":"20","author":"You","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.jhep.2020.09.034_bib27","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jhep.2012.02.010","article-title":"EASL clinical practice guidelines: management of chronic hepatitis B virus infection","volume":"57","year":"2012","journal-title":"J\u00a0Hepatol"},{"issue":"Suppl 1","key":"10.1016\/j.jhep.2020.09.034_bib28","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1440-1746.2010.06544.x","article-title":"Chronic hepatitis B in Asia-new insights from the past decade","volume":"26","author":"Chan","year":"2011","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib29","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1111\/j.1478-3231.2005.01134.x","article-title":"Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2005 update","volume":"25","author":"Liaw","year":"2005","journal-title":"Liver Int"},{"key":"10.1016\/j.jhep.2020.09.034_bib30","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1093\/infdis\/jiz326","article-title":"Longitudinal change of body mass index is associated with alanine aminotransferase elevation after complete viral suppression in chronic hepatitis B patients","volume":"220","author":"Wang","year":"2019","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.jhep.2020.09.034_bib31","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.jhep.2018.05.019","article-title":"Non-invasive prediction of esophageal varices by stiffness and platelet in non-alcoholic fatty liver disease cirrhosis","volume":"69","author":"Petta","year":"2018","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib32","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/liv.13945","article-title":"How to clarify the Baveno VI criteria for ruling out varices needing treatment by noninvasive tests","volume":"39","author":"Cales","year":"2019","journal-title":"Liver Int"},{"key":"10.1016\/j.jhep.2020.09.034_bib33","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/j.jhep.2014.06.012","article-title":"Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure","volume":"61","author":"Jalan","year":"2014","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib34","doi-asserted-by":"crossref","first-page":"731","DOI":"10.4254\/wjh.v10.i10.731","article-title":"Spleen stiffness mirrors changes in portal hypertension after successful interferon-free therapy in chronic-hepatitis C virus patients","volume":"10","author":"Ravaioli","year":"2018","journal-title":"World J Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib35","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1177\/1756283X17715198","article-title":"Rapid liver and spleen stiffness improvement in compensated advanced chronic liver disease patients treated with oral antivirals","volume":"10","author":"Pons","year":"2017","journal-title":"Therap Adv Gastroenterol"},{"key":"10.1016\/j.jhep.2020.09.034_bib36","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1002\/hep.28610","article-title":"Successful antiviral treatment of chronic hepatitis C leads to a rapid decline of liver stiffness without an early effect on spleen stiffness","volume":"64","author":"Verlinden","year":"2016","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.jhep.2020.09.034_bib37","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/j.jhep.2020.05.050","article-title":"Clinical outcome and hemodynamic changes following HCV eradication with oral antiviral therapy in patients with clinically significant portal hypertension","volume":"73","author":"Lens","year":"2020","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib38","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1016\/j.cgh.2019.04.062","article-title":"Performance of Baveno VI and expanded Baveno VI criteria for excluding high-risk varices in patients with chronic liver diseases: a systematic review and meta-analysis","volume":"17","author":"Stafylidou","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.jhep.2020.09.034_bib39","article-title":"Application of supersonic shear imaging to the Baveno VI criteria and a combination model with spleen stiffness measurement to rule out high-risk varices in compensated advanced chronic liver disease","author":"Cho","year":"2020","journal-title":"Ultraschall Med"},{"key":"10.1016\/j.jhep.2020.09.034_bib40","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1111\/jvh.12114","article-title":"Modified spleen stiffness measurement by transient elastography is associated with presence of large oesophageal varices in patients with compensated hepatitis C virus cirrhosis","volume":"20","author":"Calvaruso","year":"2013","journal-title":"J\u00a0Viral Hepat"},{"key":"10.1016\/j.jhep.2020.09.034_bib41","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/liv.14228","article-title":"A\u00a0novel spleen-dedicated stiffness measurement by FibroScan(R) improves the screening of high-risk oesophageal varices","volume":"40","author":"Stefanescu","year":"2020","journal-title":"Liver Int"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827820336783?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827820336783?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T19:40:16Z","timestamp":1759174816000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827820336783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S0168827820336783"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2020.09.034","relation":{},"ISSN":["0168-8278"],"issn-type":[{"value":"0168-8278","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Baveno VI criteria and spleen stiffness measurement rule out high-risk varices in virally suppressed HBV-related cirrhosis","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2020.09.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}