{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T20:10:16Z","timestamp":1759176616220,"version":"3.44.0"},"reference-count":6,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal-of-hepatology.eu","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Hepatology"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.jhep.2021.02.022","type":"journal-article","created":{"date-parts":[[2021,2,27]],"date-time":"2021-02-27T11:01:21Z","timestamp":1614423681000},"page":"1492-1493","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reply to: \u201cFailure to control variceal bleeding: Definition matters\u201d"],"prefix":"10.1016","volume":"74","author":[{"given":"Rahul","family":"Kumar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiv","family":"Jalan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jhep.2021.02.022_bib1","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.jhep.2021.01.012","article-title":"Failure to control variceal bleeding: definition matters","volume":"74","author":"Baiges","year":"2021","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2021.02.022_bib2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jhep.2020.06.010","article-title":"Determinants of mortality in patients with cirrhosis and uncontrolled variceal bleeding","volume":"74","author":"Kumar","year":"2021","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2021.02.022_bib3","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s13054-018-2156-0","article-title":"Validation of CLIF-C ACLF score to define a threshold for futility of intensive care support for patients with acute-on-chronic liver failure","volume":"22","author":"Engelmann","year":"2018","journal-title":"Crit Care"},{"key":"10.1016\/j.jhep.2021.02.022_bib4","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1056\/NEJMoa0910102","article-title":"Early use of TIPS in patients with cirrhosis and variceal bleeding","volume":"362","author":"Garcia-Pagan","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.jhep.2021.02.022_bib5","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.jhep.2020.04.024","article-title":"Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS","volume":"73","author":"Trebicka","year":"2020","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.jhep.2021.02.022_bib6","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/apt.15797","article-title":"Randomised clinical trial: standard of care versus early-transjugular intrahepatic porto-systemic shunt (TIPS) in patients with cirrhosis and oesophageal variceal bleeding","volume":"52","author":"Dunne","year":"2020","journal-title":"Aliment Pharmacol Ther"}],"container-title":["Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827821001562?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168827821001562?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T19:40:25Z","timestamp":1759174825000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168827821001562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S0168827821001562"],"URL":"https:\/\/doi.org\/10.1016\/j.jhep.2021.02.022","relation":{},"ISSN":["0168-8278"],"issn-type":[{"type":"print","value":"0168-8278"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reply to: \u201cFailure to control variceal bleeding: Definition matters\u201d","name":"articletitle","label":"Article Title"},{"value":"Journal of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2021.02.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2021.01.012","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"https:\/\/doi.org\/10.1016\/j.jhep.2020.06.010","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}